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    Triggerable passive valve for use in controlling the flow of fluid
    53.
    发明申请
    Triggerable passive valve for use in controlling the flow of fluid 有权
    可触发的被动阀，用于控制流体的流动

    公开(公告)号：US20050217743A1

    公开(公告)日：2005-10-06

    申请号：US11096036

    申请日：2005-03-30

    申请人： Sebastian Bohm

    发明人： Sebastian Bohm

    IPC分类号： G05D7/06

    CPC分类号： G05D7/0694 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150946 ,  F16K99/00 ,  Y10T137/2196 ,  Y10T137/2224

    摘要： The present invention is directed to valves for use in controlling the flow of fluid and, more particularly, to a triggerable passive valve for use in controlling the flow of fluid. In one embodiment, a fluid delivery channel is connected to a flow restrictor and a passive valve positioned in the fluid delivery channel downstream from the flow restrictor. The first passive valve prevents fluid from moving through the channel when the pressure exerted by the fluid on the first passive valve is below the burst pressure. A pneumatic actuator actuates the valve by forcing fluid through the passive valve.

    摘要翻译： 本发明涉及用于控制流体流动的阀门，更具体地，涉及用于控制流体流动的可触发的被动阀。 在一个实施例中，流体输送通道连接到限流器和被定位在流体输送通道中的被动阀，其位于流量限制器的下游。 当第一被动阀上的流体施加的压力低于爆破压力时，第一被动阀防止流体流过通道。 气动执行器通过迫使流体通过被动阀来致动阀。

    Latching micro-regulator
    54.
    发明申请
    Latching micro-regulator 有权
    闭锁微调节器

    公开(公告)号：US20050166975A1

    公开(公告)日：2005-08-04

    申请号：US11099014

    申请日：2005-04-04

    申请人： John Gilbert ,  Bernard Bunner ,  Sebastian Bohm ,  Manish Deshpande

    发明人： John Gilbert ,  Bernard Bunner ,  Sebastian Bohm ,  Manish Deshpande

    IPC分类号： F15C5/00 ,  F16K99/00 ,  G05D7/06

    CPC分类号： F16K99/0001 ,  F15C5/00 ,  F16K99/0005 ,  F16K99/0007 ,  F16K99/0009 ,  F16K99/0015 ,  F16K99/0046 ,  F16K99/0048 ,  F16K2099/0069 ,  F16K2099/0071 ,  F16K2099/0074 ,  F16K2099/0076 ,  F16K2099/008 ,  F16K2099/0084 ,  G05D7/0694 ,  Y10T29/49412 ,  Y10T137/87314

    摘要： A latching microregulator for regulating liquid flow on micro-scale levels comprises a substrate having an inlet port and an outlet port, a valve element defining a valve chamber for opening and closing the inlet port, and an actuator assembly for actuating the valve element. The valve chamber is configured to contain a volume of fluid, and the inlet port and the outlet port are in fluid communication with the valve chamber to provide a liquid flow path through the chamber. The actuator assembly comprises a cantilever beam for moving the valve element between an open position and a closed position, an actuator, such as a piezoelectric element, for moving the cantilever beam, and a latch, such as a permanent magnet, for securing the cantilever beam in the closed position. A flow regulation system comprises a plurality of fluid channels of varied flow conductance and a plurality of latching microregulators for selectively blocking or allowing flow through each of the fluid channels.

    摘要翻译： 用于调节微量级液体流动的闭锁微调节器包括具有入口端口和出口端口的基板，限定用于打开和关闭入口端口的阀室的阀元件以及用于致动阀元件的致动器组件。 阀室被构造成容纳一定体积的流体，并且入口端口和出口端口与阀室流体连通以提供通过该腔室的液体流动路径。 致动器组件包括用于在打开位置和关闭位置之间移动阀元件的悬臂梁，用于移动悬臂梁的致动器（例如压电元件）以及用于固定悬臂的闩锁（例如永磁体） 梁处于关闭位置。 流量调节系统包括多个不同流量的流体通道和多个用于选择性地阻塞或允许流过每个流体通道的闭锁微调节器。

    Microdialysis-probe integrated with a si-chip
    55.
    发明授权
    Microdialysis-probe integrated with a si-chip 失效
    微透析探针与si芯片集成

    公开(公告)号：US06463312B1

    公开(公告)日：2002-10-08

    申请号：US09601873

    申请日：2000-09-12

    申请人： Piet Bergveld ,  Sebastian Bohm ,  Wouter Olthuis

    发明人： Piet Bergveld ,  Sebastian Bohm ,  Wouter Olthuis

    IPC分类号： A61B505

    CPC分类号： A61B5/14528

    摘要： Microdialysis device (10), comprising at least a probe (1) provided with an inlet (2) and an outlet (3) for bringing a perfusion fluid into contact with a bodily fluid in a part of a living organism and causing constituents from this fluid to be taken up by this perfusion fluid, whereby the perfusion fluid is enriched to dialysate, wherein the outlet (3) is integrally received in a silicon chip (5) and debouches in a first fluid channel (6) formed in this silicon chip (5) and wherein further at least one analysis means, for instance an ISFET (17, 18), for analysing constituents of the bodily fluid taken up by the perfusion fluid is integrally received in the silicon chip (5) in a manner such that dialysate flowing from the outlet (3) comes into contact with said analysis means in the first fluid channel (6), and wherein the silicon chip (5) is further optionally provided with pumping means (50) or dosing means.

    摘要翻译： 微透析装置（10）包括至少一个设置有入口（2）和出口（3）的探针（1），用于使灌注流体与生物体的一部分中的体液接触并引起来自该生物体的成分 流体被该灌注流体吸收，从而使灌注流体富集成透析液，其中出口（3）整体地容纳在硅芯片（5）中，并且在形成于该硅芯片中的第一流体通道（6）中脱模 （5），并且其中另外至少一个分析装置，例如用于分析由灌注流体吸收的体液的成分的ISFET（17,18）以这样的方式被一体地接收在硅芯片（5）中： 从出口（3）流出的透析液与第一流体通道（6）中的分析装置接触，并且其中硅芯片（5）还可选地设置有泵送装置（50）或给料装置。