公开(公告)号：US09029132B2

公开(公告)日：2015-05-12

申请号：US12537063

申请日：2009-08-06

申请人： Marwan H. Khater ,  Tak H. Ning ,  Lidija Sekaric ,  Sufi Zafar

发明人： Marwan H. Khater ,  Tak H. Ning ,  Lidija Sekaric ,  Sufi Zafar

IPC分类号： C12M1/34 ,  G01N33/551 ,  G01N33/543 ,  B82Y10/00 ,  G01N27/327 ,  H01L29/78

CPC分类号： G01N33/54373 ,  B82Y10/00 ,  G01N27/3276 ,  G01N27/4145 ,  G01N33/543 ,  H01L29/785 ,  Y10S977/721 ,  Y10S977/92 ,  Y10S977/953

摘要： A sensor for biomolecules includes a silicon fin comprising undoped silicon; a source region adjacent to the silicon fin, the source region comprising heavily doped silicon; a drain region adjacent to the silicon fin, the drain region comprising heavily doped silicon of a doping type that is the same doping type as that of the source region; and a layer of a gate dielectric covering an exterior portion of the silicon fin between the source region and the drain region, the gate dielectric comprising a plurality of antibodies, the plurality of antibodies configured to bind with the biomolecules, such that a drain current flowing between the source region and the drain region varies when the biomolecules bind with the antibodies.

摘要翻译： 用于生物分子的传感器包括包含未掺杂硅的硅片; 与硅鳍片相邻的源极区域，源极区域包括重掺杂的硅; 与所述硅鳍片相邻的漏极区域，所述漏极区域包括掺杂类型的与所述源极区域相同的掺杂类型的重掺杂硅; 以及覆盖源极区域和漏极区域之间的硅鳍片的外部部分的栅极电介质层，所述栅极电介质包括多个抗体，所述多个抗体被配置为与所述生物分子结合，使得漏极电流流动 当生物分子与抗体结合时，在源区和漏区之间变化。

公开(公告)号：US20120282596A1

公开(公告)日：2012-11-08

申请号：US13552727

申请日：2012-07-19

申请人： Marwan H. Khater ,  Tak H. Ning ,  Lidija Sekaric ,  Sufi Zafar

发明人： Marwan H. Khater ,  Tak H. Ning ,  Lidija Sekaric ,  Sufi Zafar

IPC分类号： G01N27/26

CPC分类号： G01N33/54373 ,  B82Y10/00 ,  G01N27/3276 ,  G01N27/4145 ,  G01N33/543 ,  H01L29/785 ,  Y10S977/721 ,  Y10S977/92 ,  Y10S977/953

摘要： A method for sensing biomolecules in an electrolyte includes exposing a gate dielectric surface of a sensor comprising a silicon fin to the electrolyte, wherein the gate dielectric surface comprises a dielectric material and antibodies configured to bind with the biomolecules; applying a gate voltage to an electrode immersed in the electrolyte; and measuring a change in a drain current flowing in the silicon fin; and determining an amount of the biomolecules that are present in the electrolyte based on the change in the drain current.

摘要翻译： 用于感测电解质中的生物分子的方法包括将包含硅翅片的传感器的栅极电介质表面暴露于电解质，其中所述栅极电介质表面包括电介质材料和被配置为与所述生物分子结合的抗体; 对浸在电解质中的电极施加栅极电压; 并测量在硅片中流动的漏极电流的变化; 以及基于漏极电流的变化确定存在于电解质中的生物分子的量。

公开(公告)号：US20110279125A1

公开(公告)日：2011-11-17

申请号：US12781514

申请日：2010-05-17

申请人： Stephen W. Bedell ,  Christopher D' Emic ,  Hongbo Peng ,  Sufi Zafar

发明人： Stephen W. Bedell ,  Christopher D' Emic ,  Hongbo Peng ,  Sufi Zafar

IPC分类号： G01N27/06 ,  H01L21/02

CPC分类号： B82Y15/00 ,  G01N27/02 ,  G01N27/4145 ,  G01N33/48721

摘要： A method of using a sensor comprising a field effect transistor (FET) embedded in a nanopore includes placing the sensor in an electrolyte comprising at least one of biomolecules and deoxyribonucleic acid (DNA); placing an electrode in the electrolyte; applying a gate voltage in the sub-threshold regime to the electrode; applying a drain voltage to a drain of the FET; applying a source voltage to a source of the FET; detecting a change in a drain current in the sensor in response to the at least one of biomolecules and DNA passing through the nanopore.

摘要翻译： 使用包含嵌入在纳米孔中的场效应晶体管（FET）的传感器的方法包括将传感器放置在包含生物分子和脱氧核糖核酸（DNA）中的至少一种的电解质中; 将电极放置在电解质中; 将所述子阈值状态中的栅极电压施加到所述电极; 将漏极电压施加到FET的漏极; 将源电压施加到FET的源极; 响应于生物分子和通过纳米孔的DNA中的至少一个，检测传感器中的漏极电流的变化。

公开(公告)号：US20110247946A1

公开(公告)日：2011-10-13

申请号：US12756628

申请日：2010-04-08

申请人： Donald Dorman ,  Tak Ning ,  Sufi Zafar

发明人： Donald Dorman ,  Tak Ning ,  Sufi Zafar

IPC分类号： G01N27/26 ,  G01N33/487

CPC分类号： G01N27/4145 ,  G01N27/3271 ,  G01N27/3335 ,  G01N27/414

摘要： A sensor for biomolecules or charged ions includes a substrate; a first node, a second node, and a third node located in the substrate; a gate dielectric located over the substrate, the first node, the second node, and the third node; a first field effect transistor (FET), the first FET comprising a control gate located on the gate dielectric, and the first node and the second node; and a second FET, the second FET comprising a sensing surface located on the gate dielectric, and the second node and the third node, wherein the sensing surface is configured to specifically bind the biomolecules or charged ions that are to be detected.

摘要翻译： 用于生物分子或带电离子的传感器包括基底; 第一节点，第二节点和位于所述衬底中的第三节点; 位于所述衬底，所述第一节点，所述第二节点和所述第三节点之上的栅极电介质; 第一场效应晶体管（FET），所述第一FET包括位于所述栅极电介质上的控制栅极，以及所述第一节点和所述第二节点; 以及第二FET，所述第二FET包括位于所述栅极电介质上的感测表面以及所述第二节点和所述第三节点，其中所述感测表面被配置为特异性地结合待检测的生物分子或带电离子。

公开(公告)号：US07776701B2

公开(公告)日：2010-08-17

申请号：US12190129

申请日：2008-08-12

申请人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Vijay Narayanan ,  Vamsi K. Paruchuri ,  Sufi Zafar

发明人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Vijay Narayanan ,  Vamsi K. Paruchuri ,  Sufi Zafar

IPC分类号： H01L21/336 ,  H01L21/3205 ,  H01L21/469 ,  H01L21/31 ,  H01L21/8234

CPC分类号： H01L21/28088 ,  H01L21/823828 ,  H01L29/4908 ,  H01L29/4966 ,  H01L29/513 ,  H01L29/517 ,  H01L29/518

摘要： A compound metal comprising MOxNy which is a p-type metal having a workfunction of about 4.75 to about 5.3, preferably about 5, eV that is thermally stable on a gate stack comprising a high k dielectric and an interfacial layer is provided as well as a method of fabricating the MOxNy compound metal. Furthermore, the MOxNy metal compound of the present invention is a very efficient oxygen diffusion barrier at 1000° C. allowing very aggressive equivalent oxide thickness (EOT) and inversion layer thickness scaling below 14 Å in a p-metal oxide semiconductor (pMOS) device. In the above formula, M is a metal selected from Group IVB, VB, VIB or VIIB of the Periodic Table of Elements, x is from about 5 to about 40 atomic % and y is from about 5 to about 40 atomic %.

摘要翻译： 包含MoxNy的复合金属是具有在包括高k电介质和界面层的栅叠层上热稳定的功函数为约4.75至约5.3，优选约5e的功函数的p型金属，以及 制造MOxNy复合金属的方法。 此外，本发明的MOxNy金属化合物在1000℃下是非常有效的氧扩散阻挡层，允许在p金属氧化物半导体（pMOS）器件中非常有侵蚀性的等效氧化物厚度（EOT）和低于14的反型层厚度标度 。 在上式中，M是选自元素周期表第IVB，VB，VIB或VIIB族的金属，x为约5至约40原子％，y为约5至约40原子％。

公开(公告)号：US07667277B2

公开(公告)日：2010-02-23

申请号：US11034597

申请日：2005-01-13

申请人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Dianne L. Lacey ,  Fenton R. McFeely ,  Katherine L. Saenger ,  Sufi Zafar

发明人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Dianne L. Lacey ,  Fenton R. McFeely ,  Katherine L. Saenger ,  Sufi Zafar

IPC分类号： H01L29/76

CPC分类号： H01L29/4966 ,  C23C14/0036 ,  C23C14/0635 ,  H01L21/28088 ,  H01L29/513 ,  H01L29/517 ,  H01L29/665

摘要： A compound metal comprising TiC which is a p-type metal having a workfunction of about 4.75 to about 5.3, preferably about 5, eV that is thermally stable on a gate stack comprising a high k dielectric and an interfacial layer is provided as well as a method of fabricating the TiC compound metal. Furthermore, the TiC metal compound of the present invention is a very efficient oxygen diffusion barrier at 1000° C. allowing very aggressive equivalent oxide thickness (EOT) and inversion layer thickness scaling below 14 Å in a p-metal oxide semiconductor (pMOS) device.

摘要翻译： 提供了包含TiC的复合金属，其是在包括高k电介质和界面层的栅极堆叠上具有约4.75至约5.3，优选约5e的功函数的功函数的热电稳定的p型金属，以及 制造TiC复合金属的方法。 此外，本发明的TiC金属化合物在1000℃下是非常有效的氧扩散阻挡层，允许在p金属氧化物半导体（pMOS）器件中非常有侵蚀性的等效氧化物厚度（EOT）和反型层厚度缩小至低于Å 。

公开(公告)号：US20100015790A1

公开(公告)日：2010-01-21

申请号：US12541575

申请日：2009-08-14

申请人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Dianne L. Lacey ,  Fenton R. McFeely ,  Katherine L. Saenger ,  Sufi Zafar

发明人： Alessandro C. Callegari ,  Michael A. Gribelyuk ,  Dianne L. Lacey ,  Fenton R. McFeely ,  Katherine L. Saenger ,  Sufi Zafar

IPC分类号： H01L21/28 ,  C23C14/34

CPC分类号： H01L29/4966 ,  C23C14/0036 ,  C23C14/0635 ,  H01L21/28088 ,  H01L29/513 ,  H01L29/517 ,  H01L29/665

摘要： A compound metal comprising TiC which is a p-type metal having a workfunction of about 4.75 to about 5.3, preferably about 5, eV that is thermally stable on a gate stack comprising a high k dielectric and an interfacial layer is provided as well as a method of fabricating the TiC compound metal. Furthermore, the TiC metal compound of the present invention is a very efficient oxygen diffusion barrier at 1000° C. allowing very aggressive equivalent oxide thickness (EOT) and inversion layer thickness scaling below 14 Å in a p-metal oxide semiconductor (pMOS) device.

摘要翻译： 提供了包含TiC的复合金属，其是在包括高k电介质和界面层的栅极堆叠上具有约4.75至约5.3，优选约5e的功函数的功函数的热电稳定的p型金属，以及 制造TiC复合金属的方法。 此外，本发明的TiC金属化合物在1000℃下是非常有效的氧扩散阻挡层，允许在p金属氧化物半导体（pMOS）器件中非常有侵蚀性的等效氧化物厚度（EOT）和反型层厚度缩小至低于Å 。