Dual pawl ratchet mechanism and reversing method
    51.
    发明申请
    Dual pawl ratchet mechanism and reversing method 有权
    双爪棘轮机构和倒档方法

    公开(公告)号:US20080229887A1

    公开(公告)日:2008-09-25

    申请号:US11726263

    申请日:2007-03-21

    IPC分类号: B25B13/46

    CPC分类号: B25B13/463

    摘要: A dual-pawl ratchet wrench mechanism is disclosed having a stop mechanism for limiting over-travel of a reversing lever for selecting drive directions. The stop mechanism is formed on a disc is selectively engageable with first and second pawls to move the pawls into and out of engagement with a ratchet gear to determine a torque drive direction, the ratchet gear capable of providing torque to a working piece in the selected drive direction. The design simplifies manufacturing. Additionally, the reversing lever is assembled with the mechanism in a manner to improve sealing.

    摘要翻译: 公开了一种双棘爪棘轮扳手机构,其具有用于限制用于选择驱动方向的换向杆的超行程的停止机构。 止动机构形成在盘上,其可选择性地与第一爪和第二爪接合,以将棘爪移动到与棘轮啮合的啮合中,以确定扭矩驱动方向,该棘轮能够向所选择的工件中的工件提供扭矩 驱动方向。 该设计简化了制造。 此外,换向杆与机构组装以提高密封性。

    Mounting system and method for mounting an air conditioner

    公开(公告)号:US20070068185A1

    公开(公告)日:2007-03-29

    申请号:US11239560

    申请日:2005-09-29

    IPC分类号: F25D23/12 F25D19/00

    CPC分类号: F24F1/027 F24F13/32

    摘要: A mounting system is provided for mounting an air conditioner on the exterior of a building adjacent to a window with an opening defined by a window frame having a lower sill and a height to an upper horizontal frame member. The air conditioner includes a main cabinet and a removable air duct. The mounting system includes two mounting arms, each arm being attached at a first point to a wall of the main cabinet and at a second point being engaged to the frame of the window. The main cabinet is suspended from the two mounting arms such that when mounted, a top surface of the main cabinet is positioned at a height of no more than 10% of the height of the window opening above the sill. The mounting system may provide support for the air conditioner at three points, namely, the sill of the window, an inside casing of the window and an exterior surface of the building, without requiring any fasteners to be driven into any of these points.

    Apparatus and methods for treating sleep apnea
    53.
    发明申请
    Apparatus and methods for treating sleep apnea 有权
    用于治疗睡眠呼吸暂停的装置和方法

    公开(公告)号:US20060157055A1

    公开(公告)日:2006-07-20

    申请号:US10541255

    申请日:2003-12-30

    IPC分类号: A62B7/00 A61M16/00 A62B9/00

    摘要: An apparatus and method for treating sleep apnea and/or snoring is provided. The apparatus includes an appliance sized and structured to be placed in the pharyngeal region of a human or animal and being effective in treating sleep apnea and/or snoring, for example in maintaining openness of an oropharyngeal region of a human or animal during natural sleep, advantageously while not interfering with normal functioning of the epiglottis. The appliance may be made of a super elastic material, for example, Nitinol, and may be submucossally implanted in the pharyngeal walls.

    摘要翻译: 提供了一种治疗睡眠呼吸暂停和/或打鼾的装置和方法。 该装置包括尺寸和构造为放置在人或动物的咽部区域中并且有效治疗睡眠呼吸暂停和/或打鼾的装置,例如在自然睡眠期间维持人或动物的口咽部区域的开放性, 有利地同时不妨碍会厌的正常功能。 该器具可以由超弹性材料制成,例如镍钛诺蛋白,并可以粘膜下植入咽壁。

    Apparatus and methods for treating sleep apnea
    55.
    发明申请
    Apparatus and methods for treating sleep apnea 有权
    用于治疗睡眠呼吸暂停的装置和方法

    公开(公告)号:US20050199248A1

    公开(公告)日:2005-09-15

    申请号:US11126649

    申请日:2005-05-10

    摘要: An apparatus and method for treating sleep apnea and/or snoring is provided. The apparatus includes an appliance sized and structured to be placed in the pharyngeal region of a human or animal and being effective in treating sleep apnea and/or snoring, for example in maintaining openness of an oropharyngeal region of a human or animal during natural sleep, advantageously while not interfering with normal functioning of the epiglottis. Preferably, the appliance is non-circumferential in form and includes rounded, spaced apart end portions.

    摘要翻译: 提供了一种治疗睡眠呼吸暂停和/或打鼾的装置和方法。 该装置包括尺寸和构造为放置在人或动物的咽部区域中并且有效治疗睡眠呼吸暂停和/或打鼾的装置,例如在自然睡眠期间保持人或动物的口咽部区域的开放性, 有利地同时不妨碍会厌的正常功能。 优选地,该器具是非圆周形的并且包括圆形的间隔开的端部。

    Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
    56.
    发明申请
    Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same 失效
    糖肽抗生素,糖肽抗生素组合文库及其生产方法

    公开(公告)号:US20050075483A1

    公开(公告)日:2005-04-07

    申请号:US10676391

    申请日:2003-10-01

    摘要: A glycopeptide of the formula A1-A2-A3-A4-A5-A6-A7, in which each dash represents a covalent bond; wherein A1 comprises a modified or unmodified α-amino acid residue, alkyl, aryl, aralkyl, alkanoyl, aroyl, aralkanoyl, heterocyclic, heterocyclic-carbonyl, heterocyclic-alkyl, heterocyclic-alkyl-carbonyl, alkylsulfonyl, arylsulfonyl, guanidinyl, carbamoyl, or xanthyl; wherein each of A2 to A7 comprises a modified or unmodified α-amino acid residue, whereby (i) A1 is linked to an amino group on A2, (ii) each of A2, A4 and A6 bears an aromatic side chain, which aromatic side chains are cross-linked together by two or more covalent bonds, and (iii) A7 bears a terminal carboxyl, ester, amide, or N-substituted amide group; and wherein one or more of A1 to A7 is linked via a glycosidic bond to one or more glycosidic groups each having one or more sugar residues, at least one of the sugar residues bearing one or more substituents of the formula YXR, N+(R1)═CR2R3, N═PR1R2R3, N+R1R2R3 or P+R1R2R3 in which Y is a single bond, O, NR1 or S; X is O, NR1, S, SO2, C(O)O, C(O)S, C(S)O, C(S)S, C(NR1)O, C(O)NR1, or halo (in which case Y and R are absent). A chemical library comprising a plurality of the glycopeptides of the invention. A method for preparing a glycopeptide by glycosylation of an aglycone derived from a glycopeptide antibiotic. A method for preparing a glycopeptide by preparing a pseudoaglycone from a glycopeptide antibiotic and glycosylating the pseudoaglycone.

    摘要翻译: 式A1-A2-A3-A4-A5-A6-A7的糖肽,其中每个短划线代表共价键; 其中A1包含经修饰或未修饰的α-氨基酸残基,烷基,芳基,芳烷基,烷酰基,芳酰基,芳烷酰基,杂环,杂环羰基,杂环烷基,杂环 - 烷基 - 羰基,烷基磺酰基,芳基磺酰基,胍基,氨基甲酰基或 呫吨 其中A2至A7各自包含经修饰或未修饰的α-氨基酸残基,由此(i)A1与A2上的氨基连接,(ii)每个A2,A4和A6均带有芳香侧链,该芳族侧 链通过两个或更多个共价键交联在一起,和(iii)A7具有末端羧基,酯,酰胺或N-取代的酰胺基; 并且其中A1至A7中的一个或多个通过糖苷键连接至每个具有一个或多个糖残基的一个或多个糖苷基,至少一个含有一个或多个式YXR,N + (R1)= CR2R3,N = PR1R2R3,N + R1R2R3或P + R1R2R3,其中Y为单键,O,NR1或S; X是O,NR1,S,SO2,C(O)O,C(O)S,C(S)O,C(S)S,C(NR1)O,C(O)NR1或卤素 哪种情况下Y和R不存在)。 包含本发明多种糖肽的化学文库。 通过糖衍生自糖肽抗生素的糖苷配基制备糖肽的方法。 一种通过从糖肽抗生素制备假糖苷配基并糖基化假糖苷配基来制备糖肽的方法。

    Knowledge management system and method
    57.
    发明授权
    Knowledge management system and method 有权
    知识管理系统与方法

    公开(公告)号:US06873430B2

    公开(公告)日:2005-03-29

    申请号:US09746913

    申请日:2000-12-22

    IPC分类号: G06F17/30 G06K15/00 G06K9/64

    CPC分类号: G06F17/30011

    摘要: A knowledge management system according to the invention uses print cover sheets to connect users to knowledge relevant both to the user and the communities to which they belong by making use of the declaration of relevance implicit in the print process. The cover sheet becomes an input, output and surrogate document mechanism enabling access to both document repositories and associated knowledge management services, such as for example, document related services and a recommender service.

    摘要翻译: 根据本发明的知识管理系统使用打印封面来通过利用印刷过程中隐含的相关声明来将用户连接到与用户及其所属社区相关的知识。 封面成为输入,输出和代理文档机制,能够访问文档存储库和相关知识管理服务,例如文档相关服务和推荐器服务。