公开(公告)号：US20200030791A1

公开(公告)日：2020-01-30

申请号：US16095371

申请日：2016-05-31

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Shameed Sait M.A. ,  Manish Giri

IPC: B01L3/00 ,  A61B5/026

Abstract: A method for handling multimode microfluidic data may output first signals from a first sensor on a microfluidic chip, may output second signals from a second sensor on the microfluidic chip and may output a single data stream from the microfluidic chip. The single data stream may include the first signals from the first sensor and the second signals from the second sensor. The method may further receive the single data stream from the microfluidic chip, route the first signals from the first sensor to a first data processing thread and route the second signals from the second sensor to a second data processing thread.

公开(公告)号：US10399079B2

公开(公告)日：2019-09-03

申请号：US15546735

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas McGuinness ,  Chantelle Domingue ,  Manish Giri ,  Jeremy Sells

IPC: B01L3/00 ,  G01N27/07 ,  G01N33/487

Abstract: A microfluidic diagnostic device may comprise a fluid inlet to receive a fluid from a fluidic slot, a main microfluidic channel fluidly coupled to the fluid inlet, and a main microfluidic pump interposed between the fluid inlet and the main microfluidic channel to continuously circulate a fluid through the fluidic slot, fluid inlet, and main microfluidic channel wherein the width of the fluid inlet is different from the width of the main microfluidic channel. A diagnostic device, comprising a fluidic slot, a fluid inlet fluidly coupled to the fluidic slot, a main channel fluidly coupled to the fluid inlet, and an inlet pump interposed between the fluid inlet and channel wherein the cross-sectional area of the fluid inlet is relatively larger at least one point than the cross-sectional area of the channel.

公开(公告)号：US20180321263A1

公开(公告)日：2018-11-08

申请号：US15749006

申请日：2016-03-07

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Rachel M. White ,  Manish Giri ,  Chantelle Domingue ,  Joshua M. Yu ,  Matthew David Smith ,  Sait M A Shameed

IPC: G01N33/86 ,  B01L3/00

CPC classification number: G01N33/86 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2400/0406 ,  B01L2400/0442 ,  B01L2400/0487 ,  G01N33/49 ,  G01N33/6893

Abstract: Examples herein provide a device. The device includes a testing cassette including: a microfluidic channel connecting an input port at a first end to at least one sensor area at a second end, the channel is to allow a blood sample to flow from the input port to the at least one sensor area; at least two electrodes; and a micro-fabricated integrated sensor, wherein when an electrical potential difference is applied over the blood sample, the sensor is to measure, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from the input port to the at least one sensor area and begin to coagulate, thereby obtaining a measurement function as a function of time. The device includes a processor to correlate the measurement function to a characteristic of the blood sample.

公开(公告)号：US20180214867A1

公开(公告)日：2018-08-02

申请号：US15748535

申请日：2016-01-29

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Matthew David Smith ,  Manish Giri ,  Chantelle Domingue

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L2300/0627 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0442 ,  C12M23/16 ,  G11C19/28 ,  G16H40/63 ,  G16H50/20

Abstract: Provided herein are a system and method for using a microfluidics device. The system includes: a plurality of pumps and a plurality of sensors; a first communication line to select a pump from the plurality of pumps and select a sensor from the plurality of sensors; a second communication line selectively connected to the selected pump; and a third communication line selectively connected to the selected sensor.

公开(公告)号：US20180021777A1

公开(公告)日：2018-01-25

申请号：US15546742

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Manish Giri ,  Chantelle E. Domingue ,  Robert J. Moline

IPC: B01L3/00 ,  G01N15/10 ,  G01N33/86 ,  G01N15/02

CPC classification number: B01L3/502715 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2300/044 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/088 ,  B01L2300/0883 ,  B01L2400/0406 ,  B01L2400/0439 ,  B01L2400/0442 ,  B01L2400/086 ,  G01N15/0266 ,  G01N15/1031 ,  G01N15/1056 ,  G01N33/86 ,  G01N2015/0065

Abstract: A fluid testing cassette may comprise a microfluidic channel extending having a constriction and a micro-fabricated integrated sensor within the constriction. In one implementation, the constriction is less than or equal to 30 μm. In one implementation, the cassette further comprises a nozzle connecting the microfluidic channel to the discharge reservoir, wherein a thermal resistor expels fluid within the microfluidic channel into the discharge reservoir.

公开(公告)号：US20180021776A1

公开(公告)日：2018-01-25

申请号：US15546498

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Manish Giri ,  Melinda M. Valencia ,  Matthew David Smith ,  Sirena Lu ,  Joshua M Yu ,  Sadig Bengali

IPC: B01L3/00 ,  H02M3/155

CPC classification number: B01L3/502715 ,  B01L3/5027 ,  B01L3/50273 ,  B01L3/502753 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2200/143 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/027 ,  B01L2300/0663 ,  B01L2300/088 ,  B01L2400/046 ,  B01L2400/0475 ,  G01N33/48714 ,  H02M3/155

Abstract: A system may comprise a voltage upconverter, a universal serial bus (USB) connector to receive an input voltage from a USB port on a computing device, and a microfluidic diagnostic chip communication link to electrically couple the voltage upconverter to a microfluidic diagnostic chip wherein the voltage upconverter is to convert the input voltage to be received by the USB connector to an output voltage sufficient to drive a pump on the microfluidic diagnostic chip. A diagnostic system may comprise a microfluidic diagnostic chip comprising a pump and a voltage upconverter to receive an input voltage from a universal serial bus (USB) port of a computing device and to convert the input voltage into an output voltage that powers activation of the pump.

公开(公告)号：US20180015461A1

公开(公告)日：2018-01-18

申请号：US15546483

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Manish Giri ,  Melinda M. Valencia ,  Matthew David Smith ,  Sirena Lu ,  Joshua M Yu ,  Sadig Bengali

IPC: B01L3/00 ,  H02M3/155

CPC classification number: B01L3/502715 ,  B01L2300/023 ,  B01L2400/0475 ,  H02J1/00 ,  H02J2001/008 ,  H02M3/155 ,  H02M3/156

Abstract: A system may comprise a voltage upconverter, a universal serial bus (USB) connector to receive an input voltage from a USB port on a computing device, and a microfluidic diagnostic chip communication link to electrically couple the voltage upconverter to a microfluidic diagnostic chip wherein the voltage upconverter is to convert the input voltage to be received by the USB connector to an output voltage sufficient to drive a pump on the microfluidic diagnostic chip. A diagnostic system may comprise a microfluidic diagnostic chip comprising a pump and a voltage upconverter to receive an input voltage from a universal serial bus (USB) port of a computing device and to convert the input voltage into an output voltage that powers activation of the pump.