Process for producing glycoprotein composition
    51.
    发明申请
    Process for producing glycoprotein composition 审中-公开
    糖蛋白组合物的制备方法

    公开(公告)号:US20060223147A1

    公开(公告)日:2006-10-05

    申请号:US11196503

    申请日:2005-08-04

    摘要: The present invention relates to a cell into which an RNA capable of suppressing the function of an enzyme catalyzing a reaction which converts GDP-mannose into GDP-4-keto,6-deoxy-GDP-mannose is introduced; a process for producing a glycoprotein using the cell; a cell into which an RNA capable of suppressing the function of an enzyme relating to modification of a sugar chain in which 1-position of fucose is bound to 6-position of N-acetylglucosamine in the reducing end through α-bond in the complex type N-glycoside-linked sugar chain, and an RNA capable of suppressing the function of an enzyme relating to synthesis of an intracellular sugar nucleotide, GDP-fucose, or an RNA capable of suppressing the function of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body are introduced; a process for producing a glycoprotein composition using the cell; and the like.

    摘要翻译: 本发明涉及能够抑制催化将GDP-甘露糖转化成GDP-4-酮,6-脱氧-GG-甘露糖的反应的酶的功能的RNA的细胞; 使用该细胞产生糖蛋白的方法; 能够抑制与糖链的修饰相关的酶的功能的RNA的细胞,其中岩藻糖的1位通过复合型中的α-键与还原末端的N-乙酰葡糖胺的6-位结合 N-糖苷连接的糖链,以及能够抑制与胞内糖核苷酸GDP-岩藻糖合成相关的酶的功能的RNA,或能够抑制与细胞内糖的运输有关的蛋白质的功能的RNA 核苷酸,GDP-岩藻糖,到高尔基体; 使用该细胞产生糖蛋白组合物的方法; 等等。

    Polymerizable sulfur-containing (meth) acrylate, polymerizable composition and optical lens
    52.
    发明授权
    Polymerizable sulfur-containing (meth) acrylate, polymerizable composition and optical lens 失效
    可聚合的含硫(甲基)丙烯酸酯,可聚合组合物和光学透镜

    公开(公告)号:US06528601B1

    公开(公告)日:2003-03-04

    申请号:US09645363

    申请日:2000-08-25

    IPC分类号: C08F2806

    摘要: There is disclosed a polymerizable sulfur-containing (meth)acrylate, it has a high refractive index, a great Abbe's number and excellent light resistance and is suitable for the production of a transparent resin which rarely smells at the time of molding and is further excellent in storage stability. A polymerizable composition containing the (meth)acrylate and an optical lens which is a cured product of the composition are also disclosed.

    摘要翻译: 公开了一种可聚合的含硫(甲基)丙烯酸酯,其折射率高,阿贝数大,耐光性优异,适用于制造在成型时很少闻到的透明树脂,并且更优异 在储存稳定性。 还公开了含有(甲基)丙烯酸酯和作为该组合物的固化物的光学透镜的可聚合组合物。

    Heat exchanger
    53.
    发明授权
    Heat exchanger 失效
    热交换器

    公开(公告)号:US4691761A

    公开(公告)日:1987-09-08

    申请号:US853694

    申请日:1986-04-18

    摘要: A heat exchanger which includes a turbulence promoter interposed between inlet and outlet ports of the heat exchanger and spring means made of a memory alloy for moving the turbulence promoter in a predetermined direction. The area of the heat transfer surface in which the heat transfer coefficient or the unit thermal conductance is increased by the turbulence promoter is changed in accordance with movement of the turbulence promoter. As a result, the heat exchanger effectiveness or temperature effectiveness is intentionally changed and the temperature at the outlet port of the heat exchanger is maintained within a certain range of temperature.

    摘要翻译: 一种热交换器,其包括置于热交换器的入口和出口之间的湍流促进器以及由用于沿预定方向移动湍流促进剂的记忆合金制成的弹簧装置。 根据湍流促进剂的移动,传热系数或单位热传导率由湍流促进剂增加的传热面的面积发生变化。 因此,热交换器的有效性或温度效能有意地改变,并且热交换器的出口处的温度保持在一定温度范围内。

    Heated toilet seat
    54.
    发明授权
    Heated toilet seat 失效
    加热马桶座

    公开(公告)号:US4446584A

    公开(公告)日:1984-05-08

    申请号:US435465

    申请日:1982-10-20

    IPC分类号: A47K13/30

    摘要: An apparatus for accommodating an electrical cord in a heated toilet seat having a toilet seat body and a base cover pivotally connected to each other, wherein an electrical cord adapted for electrical connection between a heater mounted within the toilet seat body and a controller therefore is secured at one by a grommet provided on the base cover and at the other end by a cord fastener in the toilet seat body. Sufficient cord slack is provided in the toilet seat body so that the cord may be retracted or extended during the pivoting of the toilet seat body. The cord slack is in the shape of a loop, and a guide stopper is positioned within the loop to guide the cord during extension and retraction and limit the maximum extension of the cord.

    摘要翻译: 一种用于将电线容纳在加热马桶座中的装置,其具有可枢转地彼此连接的马桶座体和基座盖,其中适于在安装在马桶座体内的加热器与控制器之间的电连接的电线被固定 在一个通过设置在基座盖上的索环,另一端由马桶座体内的绳索紧固件。 在马桶座椅主体中设置足够的帘线松弛,使得在马桶座椅本体的枢转期间,绳索可以缩回或延伸。 绳索松弛呈环形,并且引导止动器定位在环中以在伸出和缩回期间引导绳索,并限制绳索的最大延伸。

    Photochromic composition
    56.
    发明授权
    Photochromic composition 有权
    光致变色组合物

    公开(公告)号:US09234984B2

    公开(公告)日:2016-01-12

    申请号:US13814254

    申请日:2011-08-04

    摘要: A photochromic composition, which can function as an adhesive layer for bonding optical sheets made from a polycarbonate resin, may include a polyurethane-urea resin (A) obtained by reacting a polyol compound (A1), a polyisocyanate compound (A2) that has two or more isocyanato groups in the molecule, and an amino-containing compound (A3) that contains two or more isocyanato-reactive groups in the molecule, with at least one of the isocyanato-reactive groups being an amino group; and a photochromic compound (B).

    摘要翻译: 作为用于粘合由聚碳酸酯树脂制成的光学片的粘合剂层的光致变色组合物可以包括通过多元醇化合物(A1),多异氰酸酯化合物(A2)与二 或更多的分子中的异氰酸根合基团,和分子中含有两个或多个异氰酸酯基反应性基团的含氨基化合物(A3),其中至少一个异氰酸酯基反应性基团是氨基; 和光致变色化合物(B)。

    Anti-CD27 antibody
    57.
    发明授权
    Anti-CD27 antibody 有权
    抗CD27抗体

    公开(公告)号:US09023999B2

    公开(公告)日:2015-05-05

    申请号:US12494827

    申请日:2009-06-30

    摘要: The present invention provides a monoclonal antibody which specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to its extracellular region, or a method for using the same.The present invention can provide a monoclonal antibody or an antibody fragment thereof, which specifically recognizes a polypeptide encoded by CD27 gene containing an O-linked sugar chain to which galactose is not bound, and binds to its extracellular region; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which comprises the DNA; a transformant obtainable by transforming the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a diagnostic agent or a therapeutic agent comprising the antibody or the antibody fragment thereof as an active ingredient.

    摘要翻译: 本发明提供一种单克隆抗体,其特异性识别含有O-连接的糖链的CD27,其中半乳糖不结合并结合到其胞外区域,或其使用方法。 本发明可以提供一种单克隆抗体或其抗体片段,该单克隆抗体或其抗体片段特异性识别由含有O-连接的糖链的CD27基因编码的多肽,其中半乳糖未结合到其上并结合其胞外区域; 产生抗体的杂交瘤; 编码抗体的DNA; 包含DNA的载体; 通过转化载体可获得的转化体; 使用杂交瘤或转化体生产抗体或其抗体片段的方法; 以及包含该抗体或其抗体片段作为有效成分的诊断剂或治疗剂。

    Photochromic optical element
    59.
    发明授权
    Photochromic optical element 失效
    光致变色光学元件

    公开(公告)号:US08557377B2

    公开(公告)日:2013-10-15

    申请号:US12223116

    申请日:2007-01-19

    IPC分类号: B32B9/04 G02B1/10 B05D5/06

    摘要: A photochromic optical element comprising an optical substrate, a photochromic coat layer, and a hard coat layer that are laminated in this order, wherein (I) the photochromic coat layer comprising an alkylamino group-containing photochromic compound and/or a dialkylamino group-containing photochromic compound in a total amount of 0.1 to 10.0% by mass, and (II) the hard coat layer is obtained by curing a hard coat agent comprising metal oxide fine particles and an organosilicon compound, the hard coat agent containing as the organosilicon compound at least one selected from the group consisting of a tetraalkoxy silane, a methyl trialkoxy silane, and partial hydrolysates thereof in an amount of 10 to 60% by mass based on the total mass of the metal oxide fine particles and the organosilicon compound.

    摘要翻译: 1.一种光致变色光学元件,其特征在于,含有依次层叠的光学基板,光致变色涂层和硬涂层,其中,(I)含有含有烷基氨基的光致变色化合物和/或含二烷基氨基的光致变色涂层 光致变色化合物的总量为0.1〜10.0质量%,(II)硬涂层是通过将包含金属氧化物微粒和有机硅化合物的硬涂层固化而得到的,所述硬涂层包含作为有机硅化合物的硬涂层 基于金属氧化物微粒和有机硅化合物的总质量,选自由四烷氧基硅烷,甲基三烷氧基硅烷及其部分水解产物组成的组中的至少一种为10〜60质量%。

    PRIMER COMPOSITION FOR OPTICAL ARTICLES AND OPTICAL ARTICLES
    60.
    发明申请
    PRIMER COMPOSITION FOR OPTICAL ARTICLES AND OPTICAL ARTICLES 有权
    光学文章和光学文章的主要组成

    公开(公告)号:US20120019888A1

    公开(公告)日:2012-01-26

    申请号:US13260600

    申请日:2010-03-25

    IPC分类号: G02B1/10 C09D175/04 C09D7/12

    摘要: A primer coating composition is provided for an optical article capable of forming a coating layer having excellent impact resistance, abrasion resistance, and adhesion to various kinds of plastic materials without occurring of appearance faulty for an optical base material, for example, a plastic lens for an eyeglass. A primer composition for an optical article comprises; (A) aqueous dispersion of urethane resin having a polycarbonate-derived skeleton and the elongation of 200˜1000%; (B) an organic solvent having 3˜9 carbon atoms and having an ether bond or carbonyl bond and one hydroxyl group in a molecule; and (C) lower alcohol having 1˜4 carbon atoms, wherein the weight ratio of said organic solvent to said lower alcohol is from 0.01 to less than 2.00.

    摘要翻译: 提供一种底漆涂料组合物,用于能够形成具有优异的耐冲击性,耐磨性和对各种塑料材料的粘附性的涂层的光学制品,而不会出现光学基材的外观缺陷,例如塑料透镜 一个眼镜。 用于光学制品的底漆组合物包括: (A)具有聚碳酸酯衍生骨架的聚氨酯树脂的水分散体,伸长率为200〜1000%。 (B)分子中具有3〜9个碳原子并具有醚键或羰基键和1个羟基的有机溶剂; 和(C)具有1〜4个碳原子的低级醇,其中所述有机溶剂与所述低级醇的重量比为0.01至小于2.00。