公开(公告)号：US08704170B2

公开(公告)日：2014-04-22

申请号：US13634190

申请日：2011-04-22

Applicant: Sumio Kumashiro ,  Wenjian Sun ,  Li Ding

Inventor： Sumio Kumashiro ,  Wenjian Sun ,  Li Ding

IPC: H01J49/00 ,  H01J49/10 ,  H01J49/24 ,  H01J49/16

CPC classification number: H01J49/10 ,  G01N27/622 ,  H01J49/066 ,  H01J49/161 ,  H01J49/164 ,  H01J49/165 ,  H01J49/24

Abstract: The current invention involves a method and a device for generating and analyzing ions in order to analyze samples directly without sample preparation. The gaseous neutral molecules are desorbed under atmospheric pressure by a desorption method. The desorbed neutral molecules are then transferred into a low pressure region where they are post-ionized by a mist from an electrospray probe tip or by photons from a vacuum UV source. The generated ions are then focused in a time varying electric field in the low pressure chamber before they are transferred into a mass spectrometer or ion mobility spectrometer for further analysis.

Abstract translation: 本发明涉及用于生成和分析离子的方法和装置，以便在不进行样品制备的情况下直接分析样品。 气态中性分子通过解吸法在大气压下解吸。 然后将解吸的中性分子转移到低压区域，在那里它们被来自电喷雾探针尖端的雾或者来自真空UV源的光子后离子化。 然后将所产生的离子聚焦在低压室中的时变电场中，然后将其转移到用于进一步分析的质谱仪或离子迁移谱仪中。

公开(公告)号：US20130335424A1

公开(公告)日：2013-12-19

申请号：US13985834

申请日：2012-12-20

Applicant: Xiaolei Wang ,  Lei Zhang ,  Li Ding

Inventor： Xiaolei Wang ,  Lei Zhang ,  Li Ding

IPC: G06T11/60

CPC classification number: G06T11/60 ,  G06T11/203 ,  G09G5/28 ,  G09G2320/02 ,  G09G2360/16

Abstract: A character display technique relating to computer information processing to improve the display of characters. Whether a thickening process on a glyph outline corresponding to a character to be displayed is needed is determined by calculating a mean grayscale value of pixels of a grayscale bitmap of the glyph outline. if thickening is to be performed, the thickening amount is determined on the basis of the mean grayscale value of pixels, and the thickened glyph outline is output for display, thereby minimizing problems of fading of the displayed color, fuzzy strokes and the like due to strokes that are too narrow, and thus improving the character display effect.

Abstract translation: 与计算机信息处理相关的字符显示技术，以改善字符的显示。 通过计算字形轮廓的灰度位图的像素的平均灰度值来确定是否需要对应于要显示的字符的字形轮廓上的增稠处理。 如果要进行增厚，则基于像素的平均灰度值来确定增厚量，并且输出加粗的字形轮廓以进行显示，从而最小化由于显示的颜色，模糊笔画等引起的褪色的问题 笔画太窄，从而改善了人物的显示效果。

公开(公告)号：US20120310340A1

公开(公告)日：2012-12-06

申请号：US13238143

申请日：2011-09-21

Applicant: Wayne H. Knox ,  Thomas Smith ,  Dharmendra Jani ,  Li Ding

Inventor： Wayne H. Knox ,  Thomas Smith ,  Dharmendra Jani ,  Li Ding

IPC: A61F2/16 ,  B29D11/00

CPC classification number: G02B3/0087 ,  A61F2/1618 ,  A61F2/1627 ,  A61F9/00834 ,  A61L27/16 ,  A61L27/50 ,  A61L27/52 ,  A61L2400/18 ,  A61L2430/16 ,  G02B2003/0093 ,  G02C2202/12 ,  G02C2202/14 ,  C08L33/10

Abstract: A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis, and further characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.

Abstract translation: 一种用于改变光学聚合物材料的折射率的方法。 该方法包括用飞秒激光脉冲连续照射光学聚合材料的预定区域，以在材料内形成梯度折射率折射结构。 光学装置包括具有前表面和后表面的光学聚合物透镜材料和与表面相交的光轴以及设置在前表面和后表面之间并且沿着第一轴线45布置的至少一个激光修饰的GRIN层 °至90°，并且进一步的特征在于，相邻段的至少一部分中的至少一个和沿着每个段的折射率的变化。

公开(公告)号：US08242459B2

公开(公告)日：2012-08-14

申请号：US13141864

申请日：2009-12-29

Applicant: Wenjian Sun ,  Xiaohui Yang ,  Li Ding

Inventor： Wenjian Sun ,  Xiaohui Yang ,  Li Ding

IPC: H01J27/08 ,  H01J49/04 ,  H05H1/24

CPC classification number: H01J49/168

Abstract: The current invention involves a desorption corona beam ionization source/device for analyzing samples under atmospheric pressure without sample pretreatment. It includes a gas source, a gas flow tube, a gas flow heater, a metal tube, a DC power supply and a sample support/holder for placing the samples. A visible corona beam is formed at a sharply pointed tip at the exit of the metal tube when a stream of inert gas flows through the metal tube that is applied with a high DC voltage. The gas is heated for desorbing the analyte from solid samples and the desorbed species are ionized by the energized particles embedded in the corona beam. The ions formed are then transferred through an adjacent inlet into a mass spectrometer or other devices capable of analyzing ions. Visibility of the corona beam in the current invention greatly facilitates pinpointing a sampling area on the analyte and also makes profiling of sample surfaces possible.

Abstract translation: 本发明涉及一种解吸电晕束电离源/装置，用于在大气压力下分析样品而无需样品预处理。 其包括气体源，气体流管，气流加热器，金属管，直流电源和用于放置样品的样品支撑/保持器。 当惰性气体流过施加有高直流电压的金属管时，在金属管的出口处的尖锐尖端处形成可见的电晕束。 加热气体以从固体样品中解吸分析物，并且解吸物质被嵌入电晕束中的通电颗粒电离。 所形成的离子然后通过相邻入口转移到质谱仪或其他能够分析离子的装置中。 本发明中电晕束的可见性大大有助于精确分析分析物上的采样区域，并且还使得样品表面的轮廓成为可能。

公开(公告)号：US20110220790A1

公开(公告)日：2011-09-15

申请号：US13130254

申请日：2009-11-26

Applicant: Wenjian Sun ,  Li Ding

Inventor： Wenjian Sun ,  Li Ding

IPC: H01J49/22

CPC classification number: G01N27/622 ,  G01N15/0266

Abstract: A device for separating, enriching and detecting ions comprises: a gas tube, in which a carrier gas flows at a uniform rate; an ion source; multiple electrodes provided in the gas tube and applied with electric voltages respectively, so that at least an electric field is produced along the axis of the gas tube; an ion detector; and an ion extraction channel, by which specific enriched ions will be guided across the side wall of the gas tube toward the ion detector and be analyzed. The device enriches ions utilizing the following characteristic: compound ions with specific ion mobility maintain a dynamic balance for a period of time in a flow field under the combination of a carrier gas and a suitable electrical field against the direction of the carrier gas. Simultaneously, multiple compound particles with different ion motilities can be separated and enriched at positions with different electrical field intensities in a flow field in the same manner. The device also comprises synchronously export latitudinally enriched ions at different positions in a flow field, and performs later mass analysis using a mass spectrometer.

Abstract translation: 用于分离，富集和检测离子的装置包括：气体管，其中载气以均匀的速率流动; 离子源; 设置在气体管中并分别施加电压的多个电极，使得沿着气体管的轴线产生至少一个电场; 离子检测器 和离子提取通道，通过该离子提取通道将特定的富集离子引导穿过气体管的侧壁朝离子检测器进行分析。 该装置利用以下特征丰富离子：具有特定离子迁移率的复合离子在载气和合适的电场相对于载气方向的组合下在流场中保持动态平衡一段时间。 同时，具有不同离子运动的多种化合物颗粒可以以相同的方式在流场中分离富集在具有不同电场强度的位置。 该装置还包括在流场中同步输出纬向富集的离子，并使用质谱仪进行质量分析。

公开(公告)号：US07949994B2

公开(公告)日：2011-05-24

申请号：US11844121

申请日：2007-08-23

Applicant: Li Ding ,  Donald J. Yantzi

Inventor： Li Ding ,  Donald J. Yantzi

IPC: G06F9/44

CPC classification number: G06F8/00

Abstract: A method and computer program product of incrementally visualizing graphical extensible models for legacy software applications via a user interface are provided. A graph of nodes and connections showing only the highest level of details are presented. Each node that contains additional, lower level, details is shown with an expansion icon that may be selected to see additional levels of detail for the node. When selected, the user interface drills down to show the next lowest level of details for that artifact within a visual boundary of the original artifact that was expanded. Because of the nested, hierarchical nature of the model, relationships between higher level artifacts can be inferred from explicit relationships between lower level artifacts. When the node is expanded, any connections that previously connected to the higher level artifact are updated to connect to the appropriate artifact in the lower level details.

Abstract translation: 提供了一种通过用户界面逐步可视化传统软件应用程序的图形可扩展模型的方法和计算机程序产品。 提出了仅显示最高级别细节的节点和连接图。 包含附加，较低级别的详细信息的每个节点都会显示一个扩展图标，该图标可能被选择以查看该节点的附加级别的详细信息。 当选择时，用户界面向下钻取，以便在扩展的原始工件的视觉边界内显示该工件的下一个最低级别的细节。 由于模型的嵌套层次性，可以从较低级别的工件之间的显式关系推断出较高级的工件之间的关系。 当节点扩展时，先前连接到较高级别工件的任何连接都将被更新，以连接到较低级别详细信息中的相应工件。

公开(公告)号：US07861198B2

公开(公告)日：2010-12-28

申请号：US11863252

申请日：2007-09-28

Applicant: Li Ding ,  Peivand Tehrani ,  Jindrich Zejda ,  Alireza Kasnavi

Inventor： Li Ding ,  Peivand Tehrani ,  Jindrich Zejda ,  Alireza Kasnavi

IPC: G06F17/50

CPC classification number: G06F17/5031

Abstract: A method to perform timing analysis for a complex logic cell with distorted input waveform and coupled load networks is presented. Timing arc based models are used in conjunction with CCB based current models of portions of the logic cell to compute the output signal of the logic cell. For example, an intermediary signal is generated using a first timing arc based model and an equivalent coupled network output signal is generated using a channel connected block (CCB) based current model.

Abstract translation: 提出了一种对具有失真输入波形和耦合负载网络的复杂逻辑单元执行定时分析的方法。 基于时间弧的模型与基于CCB的当前模型的逻辑单元的部分结合使用以计算逻辑单元的输出信号。 例如，使用基于第一定时弧的模型生成中间信号，并且使用基于信道连接块（CCB）的当前模型生成等效的耦合网络输出信号。

公开(公告)号：US20100325605A1

公开(公告)日：2010-12-23

申请号：US12815375

申请日：2010-06-14

Applicant: Li Ding ,  Diana H. Lau ,  Elena H. Litani ,  Joanna W. Ng ,  Leho Nigul

Inventor： Li Ding ,  Diana H. Lau ,  Elena H. Litani ,  Joanna W. Ng ,  Leho Nigul

IPC: G06F9/44

Abstract: A method for implementing a graphical modeling tool in a web-based environment is disclosed herein. In one embodiment, such a method may include enabling a user to import, into a web-based environment, a domain meta model comprising a number of meta model elements. The method may further enable the user to associate the meta model elements with graphical representations in the web-based environment, thereby allowing the user to create palette elements. The user may then assemble the palette elements on a canvas to create a diagram. This diagram may be converted into an instance of the domain meta model. This instance may be validated for conformance with the rules and constraints associated with the domain meta model. A corresponding apparatus and computer program product are also disclosed and claimed herein.

Abstract translation: 本文公开了一种在基于Web的环境中实现图形建模工具的方法。 在一个实施例中，这样的方法可以包括使得用户能够将基于web的环境导入包括多个元模型元素的域元模型。 该方法还可以使用户能够将元模型元素与基于web的环境中的图形表示相关联，从而允许用户创建调色板元素。 然后，用户可以在画布上组装调色板元素以创建图。 该图可以转换成域元模型的实例。 可以验证该实例以符合与域元模型相关联的规则和约束。 本文还公开并要求对应的装置和计算机程序产品。

公开(公告)号：US07755034B2

公开(公告)日：2010-07-13

申请号：US10598185

申请日：2005-02-23

Applicant: Li Ding

Inventor： Li Ding

IPC: B01D59/44

CPC classification number: H01J49/42 ,  H01J49/0054

Abstract: A quadrupole ion trap includes a switch 3 for switching a trapping voltage between discrete voltage levels VH, VL. This creates a digital trapping field for trapping precursor ions and product ions in a trapping region of the ion trap. A gating voltage is applied to a gate electrode 12 to control injection of source electrons into the ion trap. Application of the gating voltage is synchronised with the switching so that electrons are injected into the trapping region while the trapping voltage is at a selected one of the voltage levels and can reach the trapping region with a kinetic energy suitable for electron capture dissociation to take place.

Abstract translation: 四极离子阱包括用于在离散电压电平VH，VL之间切换捕获电压的开关3。 这产生了用于在离子阱的捕获区捕获前体离子和产物离子的数字捕获场。 施加门极电压到栅电极12以控制将源电子注入到离子阱中。 门控电压的施加与开关同步，使得电子注入捕获区域，同时捕获电压处于选定的一个电压电平并且可以以适合于电子捕获解离的动能达到捕获区域发生 。

公开(公告)号：US07581211B2

公开(公告)日：2009-08-25

申请号：US10890665

申请日：2004-07-14

Applicant: Sean Eric Babineau ,  Vadim Berestetsky ,  Xuan Zhang Chen ,  Li Ding

Inventor： Sean Eric Babineau ,  Vadim Berestetsky ,  Xuan Zhang Chen ,  Li Ding

IPC: G06F9/44

CPC classification number: G06F11/3636

Abstract: On demand tracking of applications is provided by a mechanism of the present invention. After a user selects one or more units of execution of interest, a marker is assigned to each target object. Upon invocation of an application, an event is sent to an event handler if at least one target object is executed. The event handler gathers a process identifier and initiates a debugging, tracing or logging of the process on a target system.

Abstract translation: 通过本发明的机构提供应用的点播跟踪。 在用户选择一个或多个感兴趣的执行单元之后，将标记分配给每个目标对象。 在调用应用程序时，如果执行了至少一个目标对象，则会将事件发送到事件处理程序。 事件处理程序收集进程标识符，并在目标系统上启动调试，跟踪或记录进程。