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    Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    54.
    发明申请
    Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides 审中-公开
    与干细胞生长因子样多肽和多核苷酸相关的方法和材料

    公开(公告)号：US20060074044A1

    公开(公告)日：2006-04-06

    申请号：US11283290

    申请日：2005-11-18

    申请人： Ivan Labat ,  Y. Tang ,  Radoje Drmanac ,  Chenghua Liu ,  Juhi Lee ,  Nancy Mize ,  John Childs ,  Cheng-Chi Chao

    发明人： Ivan Labat ,  Y. Tang ,  Radoje Drmanac ,  Chenghua Liu ,  Juhi Lee ,  Nancy Mize ,  John Childs ,  Cheng-Chi Chao

    IPC分类号： A61K48/00 ,  C07H21/04 ,  C12P21/06 ,  C07K14/475

    CPC分类号： C07K14/475 ,  A61K38/00

    摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof the correspond to a novel human secreted stem cell growth factor-like polypeptide. These polypeptides comprise nucleic acid sequences isolated from cDNA libraries prepared from human fetal liver spleen, ovary, adult brain, lung tumor, spinal cord, cervix, ovary, endothelial cells, umbilical cord, lymphocyte, lung fibroblast, fetal brain, and testis. Other aspects of the invertion include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.

    摘要翻译： 本发明提供了由这样的多核苷酸编码的新型多核苷酸和多肽，其突变体或变体对应于新的人分泌的干细胞生长因子样多肽。 这些多肽包含从人胎肝脾，卵巢，成人脑，肺肿瘤，脊髓，子宫颈，卵巢，内皮细胞，脐带，淋巴细胞，肺成纤维细胞，胎儿脑和睾丸制备的cDNA文库中分离的核酸序列。 逆转的其他方面包括含有产生新的人分泌干细胞生长因子样多肽的方法的载体和对这些多肽特异的抗体。

    Stem cell growth factor-like polypeptides
    58.
    发明申请
    Stem cell growth factor-like polypeptides 审中-公开
    干细胞生长因子样多肽

    公开(公告)号：US20060263803A1

    公开(公告)日：2006-11-23

    申请号：US11368304

    申请日：2006-03-03

    申请人： Y. Tang

    发明人： Y. Tang

    IPC分类号： C12Q1/68 ,  C07H21/04 ,  C07K14/475

    CPC分类号： C12Q1/6888 ,  A61K38/16 ,  C07K14/47 ,  C07K14/475 ,  C12Q2600/156 ,  C12Q2600/158

    摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. In particular, the invention relates to novel stem cell growth factor-like polypeptides, including novel proteins named SCGF3248Fk081_aa2, SCGF3248Fk081_aa1, SCGFFk081_aa3, and SCGF323401Fe131_aa1. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.

    摘要翻译： 本发明提供了由对应于新型人分泌的干细胞生长因子样多肽的这种多核苷酸及其突变体或变体编码的新型多核苷酸和多肽。 特别地，本发明涉及新型干细胞生长因子样多肽，包括名为SCGF3248Fk081_aa2，SCGF3248Fk081_aa1，SCGFFk081_aa3和SCGF323401Fe131_aa1的新型蛋白质。 本发明的其它方面包括含有用于产生新的人分泌的干细胞生长因子样多肽的方法的载体和对这些多肽特异的抗体。