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    Process for preparing silk polypeptide in a controllable particle size
    51.
    发明申请
    Process for preparing silk polypeptide in a controllable particle size 有权
    制备可控粒度的丝多肽的方法

    公开(公告)号：US20080141792A1

    公开(公告)日：2008-06-19

    申请号：US11638505

    申请日：2006-12-14

    申请人： Yi Li ,  Lok Yuen Lo ,  Jun Yan Hu

    发明人： Yi Li ,  Lok Yuen Lo ,  Jun Yan Hu

    IPC分类号： G01N15/02

    CPC分类号： A61Q19/00 ,  A61K8/64 ,  A61K9/1617 ,  A61K2800/413 ,  B82Y5/00

    摘要： The present invention relates to a process for controllably producing silk particles including the steps of designing a particle size, setting parameters to create the particle size except one unknown parameter, calculating the unknown parameter using algorithm, dissolving a silk peptide in a solvent, adding a cleavage agent, and hydrolyzing the peptide to produce the particle in the desired size.

    摘要翻译： 本发明涉及一种可控制造蚕丝颗粒的方法，包括以下步骤：设计粒径，设定参数以产生除一个未知参数之外的粒度，使用算法计算未知参数，将丝肽溶解在溶剂中，加入 裂解剂，并水解该肽以产生所需大小的颗粒。

    Data acquisition source management method and system
    54.
    发明申请
    Data acquisition source management method and system 审中-公开
    数据采集​​源管理方法和系统

    公开(公告)号：US20060143281A1

    公开(公告)日：2006-06-29

    申请号：US10531942

    申请日：2003-09-12

    申请人： Yi Li

    发明人： Yi Li

    IPC分类号： G06F15/16

    CPC分类号： H04L65/4007 ,  H04L29/06 ,  H04L29/06027 ,  H04L67/1002 ,  H04L67/1029 ,  H04L67/1038 ,  H04L2029/06054 ,  H04N21/2743

    摘要： A data acquisition source management system for providing centralized management of multimedia acquisition sources and distribution of multimedia data acquired in real-time from the sources over various channels and bearers including cellular Multimedia Messaging Service (MMS) and the Internet is disclosed according to an embodiment of the invention. The data acquisition source management system and 10 method for implementing thereof, allows multimedia acquisition sources, independent of fixed-line or wireless connectivity to the Internet or an Internet protocols-enabled network, to register with a server as an acquisition source. This enables the server to monitor the acquisition source's availability with minimal setup and configuration. The server will distribute a list of available acquisition sources to users for the users to be able to request for real-time data to be captured by the acquisition sources for the data to be transmitted to the user, thereby facilitating optimal utilization of bandwidth.

    摘要翻译： 一种数据采集源管理系统，用于提供多媒体获取源的集中管理，并且通过包括蜂窝式多媒体消息服务（MMS）和因特网在内的各种信道和承载从源实时获取的多媒体数据的分发。 本发明。 数据采集​​源管理系统及其实施方式10，独立于互联网或启用因特网协议的网络的固定线路或无线连接的多媒体采集源向服务器注册为采集源。 这使得服务器能够以最小的设置和配置来监视采集源的可用性。 服务器将向用户分发可用采集源的列表，以便用户能够请求由采集源捕获的实时数据以供发送给用户的数据，从而有助于带宽的最佳利用。

    Human G-protein coupled receptor (HETGQ23)
    55.
    发明申请
    Human G-protein coupled receptor (HETGQ23) 审中-公开
    人G蛋白偶联受体（HETGQ23）

    公开(公告)号：US20060140942A1

    公开(公告)日：2006-06-29

    申请号：US11357204

    申请日：2006-02-21

    申请人： Daniel Soppet ,  Yi Li ,  Craig Rosen ,  Steven Ruben

    发明人： Daniel Soppet ,  Yi Li ,  Craig Rosen ,  Steven Ruben

    IPC分类号： A61K39/395 ,  C07H21/04 ,  C12P21/06 ,  C07K14/705

    CPC分类号： C07K14/705

    摘要： Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed were methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.

    摘要翻译： 公开了人G-蛋白偶联受体多肽和编码此类多肽的DNA（RNA）以及通过重组技术产生此类多肽的方法。 还公开了利用这些多肽来鉴定此类多肽的拮抗剂和激动剂的方法，以及分别在治疗上使用激动剂和拮抗剂治疗与G蛋白偶联受体多肽的低表达和过表达相关的病症的方法。 还公开了用于检测G蛋白偶联受体核酸序列中的突变和受体的可溶形式的改变水平的诊断方法。

    Human amine receptor
    59.
    发明申请
    Human amine receptor 审中-公开
    人类胺受体

    公开(公告)号：US20050266522A1

    公开(公告)日：2005-12-01

    申请号：US10875716

    申请日：2004-06-25

    申请人： Yi Li ,  Steven Ruben

    发明人： Yi Li ,  Steven Ruben

    IPC分类号： C07H21/04 ,  C07K14/705 ,  C12N15/12 ,  C12P21/06

    CPC分类号： C07K14/705

    摘要： A Human amine receptor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also provided are methods for detecting compounds which bind to and activate and bind to and inhibit such polypeptide and the use of compounds for treating diseases related to the under-expression and over-expression of the Human amine receptor of the present invention. Also disclosed are methods for detecting mutations in the nucleic acid sequence encoding the polypeptide and for detecting altered levels of the soluble form of the polypeptide.

    摘要翻译： 公开了人类胺受体多肽和编码这种多肽的DNA（RNA）以及通过重组技术产生这种多肽的方法。 还提供了用于检测结合并活化并结合并抑制这种多肽的化合物的方法以及用于治疗与本发明的人胺受体的低表达和过表达有关的疾病的化合物的用途。 还公开了用于检测编码多肽的核酸序列中的突变并检测多肽可溶形式的改变水平的方法。