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116 条记录 (耗时 0.047 秒)

    Leukocyte regulatory factors 1 and 2
    62.
    发明申请
    Leukocyte regulatory factors 1 and 2 审中-公开
    白细胞调节因子1和2

    公开(公告)号：US20060063924A1

    公开(公告)日：2006-03-23

    申请号：US11272833

    申请日：2005-11-15

    申请人： Jian Ni ,  Jing-Shan Hu ,  Steven Ruben ,  Reiner Gentz

    发明人： Jian Ni ,  Jing-Shan Hu ,  Steven Ruben ,  Reiner Gentz

    IPC分类号： C07K14/475 ,  C07H21/02 ,  C12P21/06

    CPC分类号： C07K14/4702

    摘要： The present invention relates to novel LRF-1 and LRF-2 proteins which are related to the CRISP family and a protein called “Neutrophil Inhibitory Factor (NIF)” isolated from the canine hookworm (Ancylostoma caninum) that potently inhibits CD11/CD18-dependent neutrophil function. In particular, isolated nucleic acid molecules are provided encoding the human LRF-1 and LRF-2 proteins. LRF-1 and LRF-2 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of LRF-1 or LRF-2 activity. Also provided are diagnostic methods for detecting immune system or other LRF-1- or LRF-2-related disorders and therapeutic methods for treating such disorders.

    摘要翻译： 本发明涉及与CRISP家族相关的新型LRF-1和LRF-2蛋白质，以及从犬钩虫（Ancylostoma caninum）中分离的称为“中性嗜中性粒细胞抑制因子（NIF）”的蛋白质，其有效抑制CD11 / CD18依赖性 中性粒细胞功能。 特别地，提供编码人LRF-1和LRF-2蛋白的分离的核酸分子。 还提供了LRF-1和LRF-2多肽，载体，宿主细胞以及用于制备它们的重组方法也是如此。 本发明还涉及用于鉴定LRF-1或LRF-2活性的激动剂和拮抗剂的筛选方法。 还提供了用于检测免疫系统或其他LRF-1或LRF-2相关疾病的诊断方法以及用于治疗这种疾病的治疗方法。

    Mobile communication device
    68.
    发明授权
    Mobile communication device 有权
    移动通信设备

    公开(公告)号：US08494597B2

    公开(公告)日：2013-07-23

    申请号：US12774835

    申请日：2010-05-06

    申请人： Kun-Tsan Wu ,  Wei-Shan Hu

    发明人： Kun-Tsan Wu ,  Wei-Shan Hu

    IPC分类号： H04M1/00

    CPC分类号： H04M1/0208 ,  H04M1/0216 ,  H04M1/0237

    摘要： A mobile communication device having a first side and an opposite second side, comprising a lower housing, an upper housing, a bracket and a biasing assembly. The upper housing stacked on the lower housing, the upper housing comprising a first edge located at the first side and a second edge located at the second side. The bracket is pivotably connected between the lower housing and the upper housing, to tilt the first edge of the upper housing away from the lower housing. The biasing assembly is connected between the lower housing and the upper housing, to exert a force between the lower housing and the upper housing so that the bracket rotates to tilt the first edge of the upper housing away from the lower housing.

    摘要翻译： 一种具有第一侧和相对的第二侧的移动通信装置，包括下壳体，上壳体，支架和偏置组件。 上壳体堆叠在下壳体上，上壳体包括位于第一侧的第一边缘和位于第二侧的第二边缘。 支架可枢转地连接在下壳体和上壳体之间，以使上壳体的第一边缘远离下壳体倾斜。 偏置组件连接在下壳体和上壳体之间，以在下壳体和上壳体之间施加力，使得支架旋转以使上壳体的第一边缘远离下壳体倾斜。

    Tilting portable electronic device
    69.
    发明授权
    Tilting portable electronic device 有权
    倾斜便携式电子设备

    公开(公告)号：US08442214B2

    公开(公告)日：2013-05-14

    申请号：US12825483

    申请日：2010-06-29

    申请人： Kun-Tsan Wu ,  Wei-Shan Hu

    发明人： Kun-Tsan Wu ,  Wei-Shan Hu

    IPC分类号： H04M1/00

    CPC分类号： H04M1/0237 ,  G06F1/1624 ,  G06F1/1679 ,  H04M1/0216

    摘要： A tilting portable electronic device includes a base, a cover, at least one connecting bar, a swinging plate and an elastic member. The connecting bar and the swinging plate respectively rotatably connect to the base and the cover. The elastic member is secured with the swinging plate and has an end portion slidably resisting against the cover. when the cover is opened relative to the base, the connecting bar and the swinging plate rotate to support one end of the cover in a slanted position relative to the base, the elastic member is compressed, the end portion slides and resists the cover to make the cover sliding automatically after the cover slides a predetermined distance.

    摘要翻译： 倾斜便携式电子设备包括基座，盖，至少一个连接杆，摆动板和弹性构件。 连接杆和摆动板分别可旋转地连接到基座和盖。 弹性构件用摆动板固定，并且具有可滑动地抵靠盖的端部。 当盖相对于基座打开时，连接杆和摆动板旋转以支撑盖的一端相对于基座倾斜的位置，弹性构件被压缩，端部滑动并抵抗盖以使 盖子滑动预定距离后自动滑动盖子。

    Tilting portable electronic device
    70.
    发明授权
    Tilting portable electronic device 有权
    倾斜便携式电子设备

    公开(公告)号：US08433062B2

    公开(公告)日：2013-04-30

    申请号：US12825477

    申请日：2010-06-29

    申请人： Kun-Tsan Wu ,  Wei-Shan Hu

    发明人： Kun-Tsan Wu ,  Wei-Shan Hu

    IPC分类号： H04M1/00

    CPC分类号： H04M1/0237 ,  H04M1/0216

    摘要： A tilting portable electronic device includes a housing, a cover, a sliding mechanism connecting to the housing and the cover, and at least one swing rod rotatably connecting to the cover and the housing. The sliding mechanism includes a fixing plate, a sliding plate, and an elastic member connecting the fixing plate and the sliding plate. The fixing plate is secured to the housing, the sliding plate rotatably connects to an end of the cover, the cover is pushed, the sliding plate slides to the end of the cover, the swing rod rotates to lift the other end of the cover, after the sliding plate slides over a predetermined distance. The elastic member releases energy to drive the sliding plate slide automatically, and the cover opens slantingly relative to the housing.

    摘要翻译： 倾斜便携式电子设备包括壳体，盖，连接到壳体和盖的滑动机构，以及至少一个可旋转地连接到盖和壳体的摆杆。 滑动机构包括固定板，滑板和连接固定板和滑板的弹性构件。 固定板固定在壳体上，滑动板可旋转地连接到盖的端部，盖被推动，滑板滑动到盖的端部，摆杆旋转以提升盖的另一端， 在滑板滑动预定距离之后。 弹性构件释放能量以自动地驱动滑板滑块，并且盖相对于壳体倾斜地打开。