摘要:
Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs.
摘要:
A separating plate for a fuel cell includes first and second plates, each provided with a hydrogen channel, an oxygen channel, and a coolant channel. The first and second plates are attached to one another to form a main plate such that the first and second hydrogen, oxygen, and coolant channels compose main hydrogen, oxygen, and coolant channels, respectively. The main hydrogen and oxygen channels are fluidly isolated from each other. Distal ends of the main channels each communicate with a manifold through a communication passageway configured to supply hydrogen, oxygen, or coolant to a corresponding one of the main channels.
摘要:
The present invention provides a method for accelerating activation of a fuel cell, which can significantly reduce the time required for the activation of the fuel cell and the amount of hydrogen used and facilitate the activation of the fuel cell.
摘要:
The present invention relates to a droplet jetting apparatus using electrostatic force, a manufacturing method thereof and an ink providing method thereof. The droplet jetting apparatus using electrostatic force includes a lower electrode unit in which a nozzle and a lower electrode positioned in the nozzle equipped in the upper part of a first substrate, and an ink inflow channel equipped in the lower part of the first substrate are integrally formed; an upper electrode unit having an upper electrode formed on the top surface of a second substrate and an ink discharge hole formed by being penetrated to the upper electrode from the bottom surface of the second substrate; and a bonding layer for bonding the lower electrode unit and the upper electrode unit with each other so that the nozzle is vertically aligned with the ink discharge hole. According to this configuration, the ink used in the droplet jetting apparatus is easy to select, the electrostatic force can be efficiently concentrated and manufacturing processes of the droplet jetting apparatus can be simplified.
摘要:
Disclosed are an Fc fragment modified by a non-peptide polymer, a pharmaceutical composition comprising the Fc fragment modified by the non-peptide polymer as a carrier, a complex of the Fc fragment and a drug via a linker and a pharmaceutical composition comprising such a complex. The Fc fragment modified by a non-peptide peptide according to the present invention lacks immunogenicity and effector functions. Due to these properties, the Fc fragment maintains the in vivo activity of a drug conjugated thereto in high levels, remarkably increases the serum half-life of the drug, and remarkably reduces the risk of inducing immune responses.
摘要:
The invention provides a method for fabricating a superlattice semiconductor structure capable of achieving excellent interfacial properties and uniformity. For the superlattice semiconductor structure according to the invention, a substrate is mounted on a susceptor within a process chamber. First and second source gases are supplied simultaneously to two different areas on the susceptor within the chamber to form first and second source gas areas separate from each other. The susceptor is rotated to revolve the substrate through the first and second source gas areas.
摘要:
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and a carrier substance, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
摘要:
The present disclosure relates to a method of manufacturing a multipurpose safety glove and a multipurpose safety glove manufactured thereby, and, more particularly, the present disclosure relates to a method of manufacturing a multipurpose safety glove and a multipurpose safety glove manufactured thereby in which a breakaway portion is not easily broken when general work is performed, so that a worker may be able to easily perform work tasks while wearing the safety glove. At the same time, safety requirements for the glove to be easily broken away from the hand in the case of danger are met, whereby a worker's body can be protected while maintaining working efficiency.
摘要:
Acrylic pressure-sensitive adhesive including an acrylic copolymer formed by copolymerizing: i) 81 to 96% by weight of an alkyl (meth) acrylic acid ester monomer having a carbon number of an alkyl group of 2 to 14; ii) 1 to 10% by weight of at least one monomer selected from the group consisting of an allyl ester, a vinyl ester and an unsaturated acetate; iii) 1 to 10% by weight of an acrylonitrile monomer; and iv) 0.1 to 2% by weight of a crosslinker including 5 to 15 of an alkylene oxide group, and having two or more groups of an acrylate group, a vinyl group or the combination thereof, and a surface finishing material comprising the same, which is environmentally friendly, has an excellent room temperature and an aging adhesive property, and has an excellent constructability.
摘要:
An electrolysis device with a rectifier comprises: an electrolytic cell; a joint panel with a first surface joined to the electrolytic cell; an electrode module comprising a housing, a plurality of electrodes provided inside the housing, and an auxiliary panel joined to a second surface of the joint panel, the auxiliary panel having a first end installed in the electrolytic cell and a second end perpendicularly protruding from an external periphery of a second end of the housing; a rectifier module having a second side surface from which an electrode protrudes; an L-shaped panel joined to second surface of the joint panel and any side surface of the rectifier module; and a bus bar that connects the electrode of the electrode module to the electrode of the rectifier module.