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公开(公告)号:US20160368266A1
公开(公告)日:2016-12-22
申请号:US15252433
申请日:2016-08-31
IPC分类号: B41J2/14
CPC分类号: B41J2/17596 , B41J2/1404 , B41J2/14145 , B41J2/1433 , B41J2/15 , B41J2/175 , B41J2002/14387 , B41J2002/14467 , B41J2202/12
摘要: In an embodiment, a fluid ejection device includes a die substrate having first and second fluid slots along opposite substrate sides and separated by a substrate central region. First and second internal columns of closed chambers are associated with the first and second slots, respectively, and the internal columns are separated by the central region. Fluidic channels extending across the central region fluidically couple closed chambers from the first internal column with closed chambers from the second internal column. Pump actuators in each closed chamber pump fluid through the channels from slot to slot.
摘要翻译: 在一个实施例中,流体喷射装置包括具有沿着相对基板侧并且被基板中心区分开的第一和第二流体槽的管芯基板。 封闭腔室的第一和第二内部柱分别与第一和第二狭槽相关联,并且内部柱由中心区域分开。 延伸穿过中心区域的流体通道使来自第一内部柱的封闭腔室与来自第二内部柱的闭合腔室流体耦合。 每个封闭腔室中的泵执行器通过通道从槽到槽泵送流体。
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公开(公告)号:US20150190767A1
公开(公告)日:2015-07-09
申请号:US14407005
申请日:2012-09-24
CPC分类号: B01F5/12 , B01F11/0071 , B01F13/0059 , B01F15/00493 , B01L3/50273 , B01L2300/0867 , B01L2300/0883 , B01L2400/0433 , B01L2400/0442 , B01L2400/0487
摘要: In one embodiment, a microfluidic mixing device includes a mixing channel, a fluid inlet chamber to pass fluids into the mixing channel, an axis-asymmetric mixing actuator integrated within the channel to cause fluid displacements that mix the fluids as they flow through the channel, and an outlet chamber to receive the mixed fluids.
摘要翻译: 在一个实施例中,微流体混合装置包括混合通道,用于将流体输送到混合通道中的流体入口室,集成在通道内的轴对称混合致动器,以引起当流体流过通道时混合流体的流体位移, 以及用于接收混合流体的出口室。
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公开(公告)号:US08939542B2
公开(公告)日:2015-01-27
申请号:US13925517
申请日:2013-06-24
IPC分类号: B41J29/393 , B41J2/045
CPC分类号: B41J2/0456 , B41J2/0451 , B41J2/04561 , B41J2/0458 , B41J2/04581 , B41J2/2142
摘要: A method of detecting a defective nozzle within a nozzle array, may comprise grouping each nozzle with a number of other nozzles within the nozzle array, measuring fluid output from each group of nozzles with a fluid detector, individually regrouping each nozzle within a group of nozzles whose fluid output is detected as not being commensurate with the amount of fluid that should be ejected from that group with a number of known non-defective nozzles to form a number of subsequent groups, and measuring fluid output from the subsequent groups of nozzles to determine which nozzle among the subsequent groups of nozzles is defective.
摘要翻译: 一种检测喷嘴阵列内的有缺陷的喷嘴的方法可以包括将每个喷嘴与喷嘴阵列内的多个其它喷嘴分组,用流体检测器测量来自每组喷嘴的流体输出,将一组喷嘴中的每个喷嘴分别重组 其流体输出被检测为不与应该用许多已知的无缺陷喷嘴从该组喷出的流体的量相匹配以形成多个随后的组,并且测量后续喷嘴组的流体输出以确定 后续喷嘴组中的哪个喷嘴有缺陷。
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公开(公告)号:US12031915B2
公开(公告)日:2024-07-09
申请号:US17417533
申请日:2019-04-30
IPC分类号: G01N21/64
CPC分类号: G01N21/6486 , G01N21/6454 , G01N2021/6421
摘要: An example device includes an array of sensor modules. A sensor module includes a body to be positioned in alignment with a planar target, a light source coupled to the body to emit light to the planar target along a source optical path, and a plurality of light sensors coupled to the body. Each light sensor is to sense a different wavelength of light received from the planar target along a sensor optical path. The sensor optical path is different from the source optical path. The bodies of the array of sensor modules are arranged in a planar tiling pattern with respect to a longitudinal axis of the planar target.
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公开(公告)号:US11807019B2
公开(公告)日:2023-11-07
申请号:US17312366
申请日:2019-07-31
发明人: Ronald Albert Askeland , Blair A. Butler , Ronald J. Ender , Craig L. Malik , Daniel D. Dowell , Seth Stephen Haddix , Si-Lam J. Choy , Alexander Govyadinov
IPC分类号: B41J2/175
CPC分类号: B41J2/17596
摘要: A printing fluid pen includes a plurality of fluid ports, a pressure regulator in fluid communication with a first fluid port, and a valve in fluid communication with a second fluid port. The first fluid port is to deliver printing fluid to a fluid ejection device, and the second fluid port is to direct printing fluid out of the pen. In response to negative pressure, the valve is to open to enable fluids within the pen to exit via the second port.
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公开(公告)号:US20230303996A1
公开(公告)日:2023-09-28
申请号:US18023316
申请日:2020-08-28
发明人: Jacob Shane Sasser , Alexander Govyadinov , Brian J. Keefe , David S. Clague , Natalie Taylor Weisenburger , Nicolas Robert Medjo
CPC分类号: C12N15/1006 , B01L3/502761 , B01L2400/086 , B01L2200/0652
摘要: In one example in accordance with the present disclosure, a fluid manipulation system is described. The fluid manipulation system includes a microfluidic channel through which fluid is to flow. The fluid includes biomolecules to be separated. The fluid manipulation system also includes at least one array of biomolecule-capturing pillars disposed within the microfluidic channel to capture biomolecules from the fluid. Barriers rise from a surface of the microfluidic channel. The barriers span a width of the microfluidic channel orthogonal to a flow of the fluid to induce vortices in the fluid flow.
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公开(公告)号:US20230287479A1
公开(公告)日:2023-09-14
申请号:US18016860
申请日:2020-07-21
IPC分类号: C12Q1/6823 , B01L3/00 , B01L7/00
CPC分类号: C12Q1/6823 , B01L3/502761 , B01L7/00 , B01L2200/0652 , B01L2200/16 , B01L2300/0654 , B01L2400/0487 , B01L2300/088 , B01L2300/1805
摘要: An example method, consistent with the present disclosure, includes receiving in a microfluidic channel, a fluid sample and a reagent, where the reagent includes a reporter nucleic acid labeled with a detectable ligand. The method further includes identifying a target nucleic acid in the fluid sample using a guide ribonucleic acid (gRNA) and a programmable nuclease immobilized in a side channel fluidically coupled to the microfluidic channel. Responsive to identifying the target nucleic acid in the fluid sample, the method includes causing cleavage of the detectable ligand, and detecting the detectable ligand from the cleaved reporter nucleic acid in the side channel.
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公开(公告)号:US11686327B2
公开(公告)日:2023-06-27
申请号:US16493344
申请日:2017-04-07
CPC分类号: F04F7/00 , B01L3/50273 , B01L3/502738 , B81B1/006 , F04B53/10 , B01L2200/141 , B01L2200/16 , B01L2400/0605 , B81B2201/051 , B81B2203/0338
摘要: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.
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公开(公告)号:US20230131266A1
公开(公告)日:2023-04-27
申请号:US17507152
申请日:2021-10-21
摘要: A method of alignment and fusion of cells with an electrical field includes firing a first fluid dispenser of an electrofusion device until a first impedance sensor in a first microfluidic channel of the electrofusion device detects a presence of a first cell. The method includes firing a second fluid dispenser of the electrofusion device until a second impedance sensor in a second microfluidic channel of the electrofusion device detects a presence of a second cell. The method includes moving the first cell and the second cell into a merging chamber of the electrofusion device by firing a third fluid dispenser of the electrofusion device, in response to alignment of the first cell in the first microfluidic channel with the second cell in the second microfluidic channel. The method further includes fusing the first cell and the second cell in the merging chamber by creating an electrical field in the merging chamber.
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公开(公告)号:US20230123792A1
公开(公告)日:2023-04-20
申请号:US17910130
申请日:2020-03-31
发明人: Alexander Govyadinov , Dennis M. LAZAROFF , Brett E. DAHLGREN , Stefan Enr LUCCHINI , Tod WOODFORD
摘要: The present disclosure is drawn to microfluidic devices. The microfluidic device includes a microfluidic well, a layered composite stack, and an optical sensor. The layered composite stack includes an optical filter composited with an etch-stopping layer. The optical filter defines the microfluidic well. The optical sensor is associated with the microfluidic well and has the optical filter positioned therebetween.
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