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286 条记录 (耗时 0.036 秒)

    Nano-scale magnetic solid base catalyst and its preparatiion method
    62.
    发明申请
    Nano-scale magnetic solid base catalyst and its preparatiion method 失效
    纳米级磁性固体碱催化剂及其制备方法

    公开(公告)号：US20050130838A1

    公开(公告)日：2005-06-16

    申请号：US11040408

    申请日：2005-01-21

    申请人： Xue Duan ,  Hui Zhang ,  Rong Qi

    发明人： Xue Duan ,  Hui Zhang ,  Rong Qi

    IPC分类号： B01J23/00 ,  B01J23/74 ,  B01J35/00 ,  B01J37/00 ,  B01J37/03 ,  B01J23/78

    CPC分类号： B01J37/03 ,  B01J23/002 ,  B01J23/74 ,  B01J35/0013 ,  B01J35/0033 ,  B01J37/0036 ,  B01J2523/00 ,  Y10S502/524 ,  Y10T428/2993 ,  B01J2523/22 ,  B01J2523/31 ,  B01J2523/842 ,  B01J2523/847 ,  B01J2523/27

    摘要： This invention describes a nano-scale magnetic solid base catalyst and its preparation method. The catalyst involves a magnetic core coated with a solid base active layer. The synthesis of the nano-scale magnetic cores was first carried out using a rapid nucleation method in a colloid mill reactor using a liquid-liquid reaction. The nano-scale magnetic cores were mixed with a mixed salt solution. The LDH-containing magnetic cores were prepared in a colloid mill reactor by a rapid nucleation method, and subsequently calcined to give a solid base mixed oxides coated on magnetic cores. The characteristics of this catalyst are: nano-scale, high surface area and high activity and selectivity in base-catalyzed reactions. The highly dispersed catalyst can be easily reclaimed using an external magnetic field because of its magnetism. The catalyst can be utilized in base catalysis in organic reactions such as glycol ether synthesis, ester exchange, aldol condensation, etc.

    摘要翻译： 本发明描述了一种纳米级磁性固体碱催化剂及其制备方法。 催化剂包括涂覆有固体碱性活性层的磁芯。 首先使用液 - 液反应在胶体磨反应器中使用快速成核法进行纳米级磁芯的合成。 将纳米级磁芯与混合盐溶液混合。 通过快速成核法在胶体磨反应器中制备含LDH的磁芯，随后煅烧，得到涂覆在磁芯上的固体基础混合氧化物。 该催化剂的特征是：纳米级，高表面积，碱催化反应中的高活性和选择性。 高度分散的催化剂由于其磁性而可以使用外部磁场容易地回收。 催化剂可用于有机反应的碱催化，如二醇醚合成，酯交换，醛醇缩合等。

    Apparatus for volumetric metering of small quantity of powder from fluidized beds
    63.
    发明授权
    Apparatus for volumetric metering of small quantity of powder from fluidized beds 失效
    用于从流化床容积计量少量粉末的装置

    公开(公告)号：US06684917B2

    公开(公告)日：2004-02-03

    申请号：US10016129

    申请日：2001-12-17

    申请人： Jesse Zhu ,  Jianzhang Wen ,  Ying Liang Ma ,  Hui Zhang

    发明人： Jesse Zhu ,  Jianzhang Wen ,  Ying Liang Ma ,  Hui Zhang

    IPC分类号： B65B3100

    CPC分类号： B01J8/0035 ,  B01J8/0015 ,  B01J8/004 ,  B01J8/1809 ,  B01J8/382 ,  B01J2208/00681 ,  B01J2208/00761 ,  B01J2219/182

    摘要： The present invention provides a fluidized bed for dispensing small quantities of powders. The fluidized bed is made using a porous housing to permit injection and removal of fluid through the surrounding walls to improve the operation of the bed particularly for small particles of the group C size, including significantly reducing powder adhesion to the walls. In one aspect of the invention the fluidized bed housing is rotated about its longitudinal axis, which may be oriented at any suitable angle. A system for changing the volume of the bed is described as is a system for incorporating injection nozzles within the bed for constant agitation and prevention of powder adhering to the walls of the housing.

    摘要翻译： 本发明提供一种用于分配少量粉末的流化床。 流化床使用多孔壳体制成，以允许通过周围壁注入和除去流体，以改善床的操作，特别是对于C组尺寸的小颗粒，包括显着降低对壁的粉末附着力。 在本发明的一个方面，流化床壳体围绕其纵向轴线旋转，其可以以任何合适的角度定向。 描述了用于改变床的体积的系统，其是在床内引入注射喷嘴的系统，用于恒定搅拌并防止附着在壳体壁上的粉末。

    Cyclin/CDK associated proteins, and uses related thereto
    64.
    发明授权
    Cyclin/CDK associated proteins, and uses related thereto 失效
    细胞周期蛋白/ CDK相关蛋白及其相关用途

    公开(公告)号：US5981702A

    公开(公告)日：1999-11-09

    申请号：US531439

    申请日：1995-09-21

    申请人： Hui Zhang ,  David Beach

    发明人： Hui Zhang ,  David Beach

    IPC分类号： A61K48/00 ,  C07K14/47 ,  C12N15/12 ,  C06K1/00

    CPC分类号： C07K14/4738 ,  A01K2217/05 ,  A61K48/00 ,  C07K2319/00

    摘要： The present invention relates to the discovery in mammalian cells, particularly human cells, of novel S-phase kinase associated proteins, p19 and p45, referred to herein as "Skp". As described herein, these proteins are components of the tumor cell-specific cyclin A/CDK2 complex and function to facilitate DNA replication. Interference with p45 function in vivo prevented entry into S-phase in both normal and transformed cells. Binding data indicated that p45 and p19 associate with each other in a binary complex. Moreover, p45 is required for p19 binding to cyclin A/CDK2.

    摘要翻译： 本发明涉及在哺乳动物细胞，特别是人类细胞中发现的新型S期激酶相关蛋白p19和p45，在本文中称为“Skp”。 如本文所述，这些蛋白质是肿瘤细胞特异性细胞周期蛋白A / CDK2复合物的组分，并且有助于DNA复制。 与体内p45功能的干扰阻止了在正常细胞和转化细胞中进入S期。 绑定数据表明p45和p19在二元复合体中彼此相关联。 此外，p19是p19与细胞周期蛋白A / CDK2结合所必需的。

    Process of melt-spinning polyacrylonitrile fiber
    68.
    发明授权
    Process of melt-spinning polyacrylonitrile fiber 有权
    熔融纺丝聚丙烯腈纤维的工艺

    公开(公告)号：US08906278B2

    公开(公告)日：2014-12-09

    申请号：US13262620

    申请日：2010-01-11

    申请人： Muhuo Yu ,  Huaiping Rong ,  Keqing Han ,  Zhaohua Wang ,  Yiwei Zhang ,  Yincai Tian ,  Qinli Dong ,  Xi Zhao ,  Hui Zhang

    发明人： Muhuo Yu ,  Huaiping Rong ,  Keqing Han ,  Zhaohua Wang ,  Yiwei Zhang ,  Yincai Tian ,  Qinli Dong ,  Xi Zhao ,  Hui Zhang

    IPC分类号： D01D5/12 ,  D01D7/00 ,  D01D10/06 ,  B82Y30/00 ,  D02J1/22 ,  D01D5/06 ,  D01F1/02 ,  D01F6/18 ,  D01F9/22

    CPC分类号： B82Y30/00 ,  B29C47/0014 ,  B29C47/8895 ,  D01D5/06 ,  D01F1/02 ,  D01F6/18 ,  D01F9/22 ,  D02J1/222

    摘要： Processes for producing carbon fiber, the filament thereof and pre-oxidized fiber are provided. In one embodiment, the gel spinning of polyacrylonitrile filament is achieved by using small-molecule gelling agent, and the carbon fiber obtained thereby is increased by 15% to 40% in tensile strength and by 20% to 35% in toughness. In another embodiment, the melt spinning process of polyacrylonitrile is conducted by using imidazole type ion liquid as plasticizer, the process reduces environment pollution, is suitable for industrial production and the fiber produced thereby is improved in its strength. In yet another embodiment, polyacrylonitrile pre-oxidized fiber is produced by melt spinning, so low cost and controllable pre-oxidization of polyacrylonitrile can be achieved. In a further embodiment, high strength carbon fiber is manufactured by using polymer thickening agent. In another further embodiment, low cost and controllable pre-oxidization of polyacrylonitrile is achieved by conducting pre-oxidization before spinning, minimizing skin-core structure, so as to produce high performance carbon fiber, and reduce the production cost of carbon fiber greatly.

    摘要翻译： 提供了生产碳纤维，其长丝和预氧化纤维的方法。 在一个实施方案中，通过使用小分子胶凝剂来实现聚丙烯腈长丝的凝胶纺丝，并且由此获得的碳纤维的拉伸强度增加15％至40％，韧性增加20％至35％。 在另一个实施方案中，聚丙烯腈的熔融纺丝过程是通过使用咪唑型离子液体作为增塑剂进行的，该方法减少了环境污染，适用于工业生产，其生产的纤维的强度提高。 在另一个实施方案中，通过熔融纺丝制备聚丙烯腈预氧化纤维，因此可以实现聚丙烯腈的低成本和可控的预氧化。 在另一个实施方案中，通过使用聚合物增稠剂制造高强度碳纤维。 在另一个实施方案中，聚丙烯腈的低成本和可控的预氧化通过在纺丝之前进行预氧化，使皮芯结构最小化，从而生产高性能碳纤维，并大大降低碳纤维的生产成本来实现。

    GLYCAN AND GLYCOPEPTIDE CAPTURE AND RELEASE USING REVERSIBLE HYDRAZONE-BASED METHOD
    70.
    发明申请
    GLYCAN AND GLYCOPEPTIDE CAPTURE AND RELEASE USING REVERSIBLE HYDRAZONE-BASED METHOD 审中-公开
    使用可逆的基于水力学方法的GLYCAN和GLYCOPEPTIDE捕获和释放

    公开(公告)号：US20140135235A1

    公开(公告)日：2014-05-15

    申请号：US14124288

    申请日：2012-06-06

    申请人： Hui Zhang ,  Shuang Yang

    发明人： Hui Zhang ,  Shuang Yang

    IPC分类号： G01N33/68

    CPC分类号： G01N33/6842 ,  C07B2200/11 ,  C07K1/22 ,  C07K9/00 ,  C07K14/4725 ,  C08B37/00 ,  C08B37/0003 ,  C08H1/00 ,  C40B40/12 ,  C40B50/18 ,  G01N2400/10 ,  Y10T436/143333

    摘要： Highly specific and novel methods for reversible hydrazone solid-phase extraction (rHSPE) are provided for glycan or glycopeptide isolation from proteins, peptides, and other contaminants for glycan and glycopeptide analysis. Glycans or glycopeptides in complex mixtures can be conjugated onto solid support or affinity or chemical tags via reversible hydrazone bond. The conjugation methods of the present invention are chemically specific and provide unique means for the removal of other non-glycan containing molecules in the complex sample before the glycans or glycopeptides are hydrolyzed and recovered for analysis. The hydrazone formation and hydrolysis of the novel methods allows for the analysis of glycans and glycopeptides. The hydrazide coating on the solid-phase surfaces are useful for surface glycan capture and on target glycan analysis. Uses of the information generated by the inventive methods for diagnosis and treatment are also disclosed.

    摘要翻译： 提供用于可逆腙固相萃取（rHSPE）的高度特异性和新颖的方法，用于从聚糖和糖肽分析的蛋白质，肽和其他污染物中分离聚糖或糖肽。 复合混合物中的糖或糖肽可以通过可逆的腙键缀合到固体支持物或亲和力或化学标签上。 本发明的缀合方法是化学特异性的，并且在聚糖或糖肽被水解和回收用于分析之前提供用于去除复合物样品中其它非聚糖聚合分子的独特手段。 腙的形成和水解的新方法允许分析聚糖和糖肽。 固相表面上的酰肼涂层可用于表面聚糖捕获和目标聚糖分析。 还公开了通过本发明的诊断和治疗方法产生的信息的使用。