公开(公告)号：US08722646B2

公开(公告)日：2014-05-13

申请号：US12680527

申请日：2008-09-26

申请人： Eric Hsu ,  Carlos Fleet ,  Anthony Cheung ,  Jun Gao

发明人： Eric Hsu ,  Carlos Fleet ,  Anthony Cheung ,  Jun Gao

IPC分类号： A61K31/722 ,  A61K48/00 ,  C07H21/04

CPC分类号： C08B37/0063 ,  A61K31/7088 ,  C07H17/02 ,  C12N15/87 ,  Y10T428/2982

摘要： The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provided are methods for altering the diameter of chitosan-nucleic acid polyplexes.

摘要翻译： 本发明提供高度浓缩的壳聚糖 - 核酸复合物组合物和分散体，以及用于制备组合物和分散体的方法。 混合壳聚糖 - 核酸复合物的方法包括壳聚糖溶液和核酸溶液的在线混合，随后进一步浓缩壳聚糖 - 核酸复合物的分散体，任选地与聚集抑制剂。 还提供了改变壳聚糖 - 核酸复合物直径的方法。

公开(公告)号：US20130287812A1

公开(公告)日：2013-10-31

申请号：US13504210

申请日：2011-11-11

申请人： Jun Gao ,  Weicheng Zhao ,  Zhumu Bai ,  Huilin Zhao ,  Qingyi Zhang ,  Haichun Yu ,  Junwei Yang ,  Feifei Sun

发明人： Jun Gao ,  Weicheng Zhao ,  Zhumu Bai ,  Huilin Zhao ,  Qingyi Zhang ,  Haichun Yu ,  Junwei Yang ,  Feifei Sun

IPC分类号： A61K39/205

CPC分类号： A61K39/205 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/541 ,  A61K2039/55505 ,  A61K2039/585 ,  A61K2039/70 ,  C12N2710/20034 ,  C12N2760/20134

摘要： This invention disclosed an anti-HPV drug and its applications in preparing medicines for treatment of HPV (human papilloma virus) infection. This drug was characterized by using human rabies vaccine as its active ingredient and being produced by adding pharmacologically acceptable carriers. This invention also disclosed drug applications in preparing medicines for treatment of HPV infection, i.e. new applications of human rabies vaccines for preparing medicines against HPV infection. The anti-HPV drug described in this invention (i.e. human rabies vaccine) had obvious treatment effects on HPV infection. According to the animal tests and preclinical observation, this drug provided satisfactory and beneficial effects and had the characteristics of safety, effectiveness and nearly no recurrence after treatment; the negative-conversion rate in patients with positive HPV-infection reached 90% after treatment.

摘要翻译： 本发明公开了一种抗HPV药物及其在制备用于治疗HPV（人乳头瘤病毒）感染的药物中的应用。 该药物的特征在于使用人狂犬病疫苗作为其活性成分，并通过加入药理学上可接受的载体产生。 本发明还公开了用于制备用于治疗HPV感染的药物的药物应用，即用于制备针对HPV感染的药物的人类狂犬病疫苗的新应用。 本发明所述的抗HPV药物（即人狂犬病疫苗）对HPV感染具有明显的治疗效果。 根据动物试验和临床前观察，该药提供了令人满意的有益效果，治疗后具有安全性，有效性和几乎无复发的特点。 治疗后HPV感染阳性患者的阴性转化率达到90％。

公开(公告)号：US08532338B2

公开(公告)日：2013-09-10

申请号：US10883846

申请日：2004-07-06

申请人： Raymond G. Beausoleil, Jr. ,  Jun Gao ,  Carl E. Picciotto

发明人： Raymond G. Beausoleil, Jr. ,  Jun Gao ,  Carl E. Picciotto

IPC分类号： G06K9/00

CPC分类号： G06T5/003 ,  G06T5/50 ,  G06T7/254 ,  G06T2207/20201

摘要： A method and system for compensating for motion blur in optical navigation adds a correction offset to an image navigation value to adjust for varying velocities along a moving web. Reference and comparison images are acquired at different times from a moving web. An optical navigation value is computed representative of the movement of the web from the reference image to the comparison image. Blur distances for the two images can be calculated. A navigation error correction value is computed as one-half the difference between the reference blur distance and the comparison blur distance. A compensated navigation value is computed by adding the error correction value to the computed navigation value to compensate for varying web velocities.

摘要翻译： 用于补偿光学导航中的运动模糊的方法和系统为图像导航值增加了校正偏移量，以便根据移动的网络对变化的速度进行调整。 参考和比较图像在不同的时间从移动的网络获取。 计算光学导航值，代表网络从参考图像到比较图像的移动。 可以计算两个图像的模糊距离。 导航误差校正值被计算为参考模糊距离和比较模糊距离之差的二分之一。 通过将误差校正值与计算的导航值相加来补偿补偿导航值，以补偿不同的速度。

公开(公告)号：US20130178516A1

公开(公告)日：2013-07-11

申请号：US13725265

申请日：2012-12-21

申请人： Feng Wei ,  Zhengliang Ye ,  Jun Gao ,  Chongnian Luo ,  Dekun Li ,  Jianming Chen ,  Yonghong Zhu ,  Junfeng Xiong ,  Xiaoli Zheng ,  Guangming Zhang ,  Ying Zhao

发明人： Feng Wei ,  Zhengliang Ye ,  Jun Gao ,  Chongnian Luo ,  Dekun Li ,  Jianming Chen ,  Yonghong Zhu ,  Junfeng Xiong ,  Xiaoli Zheng ,  Guangming Zhang ,  Ying Zhao

IPC分类号： A61K31/357 ,  A61K31/015

CPC分类号： A61K31/357 ,  A61K9/0095 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/2846 ,  A61K9/2866 ,  A61K9/4866 ,  A61K31/01 ,  A61K31/015 ,  A61K36/185 ,  A61K47/06 ,  A61K47/10 ,  A61K47/14 ,  A61K47/24 ,  A61K47/26 ,  A61K47/44

摘要： The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori -induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.

摘要翻译： 本发明涉及植物提取物，具体涉及中药藜藜提取物及其组合物。 中药藜藜提取物通过常规挥发油提取方法制备，可用于治疗幽门螺杆菌诱导的胃炎，胃溃疡等消化系统疾病，易于获得 原料，制剂简单，效果突出，副作用少。

公开(公告)号：US20120145048A1

公开(公告)日：2012-06-14

申请号：US13046799

申请日：2011-03-14

申请人： Jun Gao

发明人： Jun Gao

IPC分类号： A47B21/00

CPC分类号： A47B3/06 ,  A47B21/00

摘要： A collapsible computer desk includes a desktop, a left frame, a right frame, two inner side-plates, a lower frame, plural middle support plates, a back plate and a drawer. The inner side-plates are secured to the desktop and also secured to the both ends of the lower frame. The back plate is connected to the back portion of the lower frame and the bottom surface of the desktop. Further comprised is a plurality of assembled closures. Each assembled closure is constructed of a male closure and a female closure. The male closures of the plurality of the closures are fixedly secured onto vertical plates of the left and right frames respectively, while the female closures are fixedly secured onto the both ends of the lower frame respectively. Each male closure detachably engages the corresponding female closure.

摘要翻译： 可折叠的计算机桌面包括桌面，左框架，右框架，两个内侧板，下框架，多个中间支撑板，后板和抽屉。 内侧板固定在桌面上并固定在下框架的两端。 背板连接到下框架的后部和桌面的底面。 还包括多个组装的封闭件。 每个装配的封闭物由阳性封闭物和阴型封闭物构成。 多个封闭件的阳闭合分别牢固地固定在左框架和右框架的垂直板上，而阴盖分别牢固地固定在下框架的两端。 每个男性封闭件可拆卸地接合相应的阴盖。

公开(公告)号：US07734084B2

公开(公告)日：2010-06-08

申请号：US11584074

申请日：2006-10-20

申请人： Duncan Stewart ,  Carl Picciotto ,  Jun Gao

发明人： Duncan Stewart ,  Carl Picciotto ,  Jun Gao

IPC分类号： G06K9/00

CPC分类号： G06K9/3216 ,  G06K2009/3225 ,  G06K2209/19 ,  G06T7/33 ,  G06T2207/30148

摘要： A method for determining an offset vector. The method includes obtaining an image of a first feature. An image of a second feature is also obtained. Also, a combination image of the first feature and the second feature is obtained. A plurality of composite images is utilized to determine an accurate offset vector between the first feature and the second feature in the combination image. The plurality of composite images is based on the image of the first feature and the image of the second feature.

摘要翻译： 一种用于确定偏移矢量的方法。 该方法包括获得第一特征的图像。 还获得第二特征的图像。 此外，获得第一特征和第二特征的组合图像。 使用多个合成图像来确定组合图像中第一特征和第二特征之间的精确偏移矢量。 多个合成图像基于第一特征的图像和第二特征的图像。

公开(公告)号：US20090079780A1

公开(公告)日：2009-03-26

申请号：US11860507

申请日：2007-09-24

申请人： Carl E. Picciotto ,  Jun Gao

发明人： Carl E. Picciotto ,  Jun Gao

IPC分类号： G03G21/00 ,  B41J29/38 ,  B41J29/393

CPC分类号： B41J29/393 ,  G03G15/5062 ,  G03G2215/0059 ,  G03G2215/00776 ,  G03G2215/0158

摘要： A reference image of an area of a print media is captured at approximately a first time by an image acquisition system. A first application of ink is applied onto the print media area by a printing assembly at the first time. A comparison image of the print media area is captured at a second time by the image acquisition system subsequent to the first application of ink onto the print media area. The reference image and the comparison image are processed to determine a relative displacement of a feature pattern on the print media between approximately the first time and the second time. A second application of ink from the printing assembly onto the print media is adjusted based on the determination.

摘要翻译： 由图像采集系统在大约第一时间捕获打印介质的区域的参考图像。 第一次使用墨水通过印刷组件在印刷介质区域上施加。 在将墨水首次施加到打印介质区域之后，由图像采集系统第二次捕获打印介质区域的比较图像。 处理参考图像和比较图像以在大约第一时间和第二时间之间确定打印介质上的特征图案的相对位移。 基于该确定来调整从打印组件到打印介质的墨水的第二次应用。

公开(公告)号：US20080094629A1

公开(公告)日：2008-04-24

申请号：US11584461

申请日：2006-10-20

申请人： Wei Wu ,  Warren Robinett ,  Shih-Yuan Wang ,  Jun Gao ,  Zhaoning Yu

发明人： Wei Wu ,  Warren Robinett ,  Shih-Yuan Wang ,  Jun Gao ,  Zhaoning Yu

IPC分类号： G01B11/00

CPC分类号： G03F9/7049 ,  G03F9/7003

摘要： Lithography tools and substrates are aligned by generating geometric interference patterns using optical gratings associated with the lithography tools and substrates. In some embodiments, the relative position between a substrate and lithography tool is adjusted to cause at least one geometric shape to have a predetermined size or shape representing acceptable alignment. In additional embodiments, Moiré patterns that exhibit varying sensitivity are used to align substrates and lithography tools. Furthermore, lithography tools and substrates are aligned by causing radiation to interact with optical gratings positioned between the lithography tools and substrates. Lithography tools include an optical grating configured to generate a portion of an interference pattern that exhibits a sensitivity that increases as the relative position between the tools and a substrate moves towards a predetermined alignment position.

摘要翻译： 通过使用与光刻工具和衬底相关的光栅产生几何干涉图案来对准平版印刷工具和衬底。 在一些实施例中，调整衬底和光刻工具之间的相对位置以使得至少一个几何形状具有表示可接受对准的预定尺寸或形状。 在另外的实施例中，使用呈现不同灵敏度的莫尔图案来对准衬底和光刻工具。 此外，光刻工具和衬底通过使辐射与位于光刻工具和衬底之间的光栅相互作用来对准。 平版印刷工具包括光栅，其被配置为产生表现出灵敏度的一部分干涉图案，该灵敏度随着工具和基板之间的相对位置朝向预定对准位置移动而增加。

公开(公告)号：US20080084006A1

公开(公告)日：2008-04-10

申请号：US11548216

申请日：2006-10-10

申请人： Jun Gao ,  Wei Wu ,  Carl Picciotto

发明人： Jun Gao ,  Wei Wu ,  Carl Picciotto

IPC分类号： B29C59/00

CPC分类号： G03F7/2014 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

摘要： A contact lithography apparatus, system and method use a hydraulic deformation to facilitate pattern transfer. The apparatus, system and method include a spacer that provides a spaced apart proximal orientation of lithographic elements, and a hydraulic force member that provides the hydraulic deformation. One or more of the lithographic elements and the spacer is deformable, such that hydraulic deformation thereof facilitates the pattern transfer.

摘要翻译： 接触式光刻设备，系统和方法使用液压变形来促进图案转印。 装置，系统和方法包括提供光刻元件的间隔开的近端取向的间隔件，以及提供液压变形的液压力构件。 一个或多个光刻元件和间隔件是可变形的，使得其液压变形有利于图案转印。

公开(公告)号：US20080026305A1

公开(公告)日：2008-01-31

申请号：US11492838

申请日：2006-07-26

申请人： Wei Wu ,  William M. Tong ,  Jun Gao ,  Carl Picciotto

发明人： Wei Wu ,  William M. Tong ,  Jun Gao ,  Carl Picciotto

IPC分类号： G03F9/00 ,  G03B27/42 ,  G03C5/00

CPC分类号： G03F9/7069 ,  G03F9/7065 ,  G03F9/7088

摘要： A method and system are disclosed for aligning a lithography template having a pattern with a substrate in preparation for transferring the pattern to a surface of the substrate. The system includes an optical imaging system adapted to image a first alignment structure formed on a top surface of the template using light of a first wavelength and a second alignment structure formed on a top surface of the substrate using light of a second wavelength.

摘要翻译： 公开了一种方法和系统，用于将具有图案的光刻模板与衬底对准以准备将图案转移到衬底的表面。 该系统包括光学成像系统，其适于使用第二波长的光形成在基板的顶表面上的第一波长的光和形成在第二对准结构上的形成在模板的顶表面上的第一对准结构。