公开(公告)号：US20180199843A1

公开(公告)日：2018-07-19

申请号：US15920080

申请日：2018-03-13

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey Gillberg

IPC: A61B5/044 ,  A61N1/372 ,  A61N1/362 ,  A61N1/37 ,  A61N1/08

CPC classification number: A61B5/044 ,  A61N1/362 ,  A61N1/371 ,  A61N1/37247 ,  A61N2001/083

Abstract: Systems, methods, and interfaces are described herein for identification of effective electrodes to be used in sensing and/or therapy. Two or more portions of a signal monitored using an electrode may be compared to determine whether the electrode is effective. The two or more portions may correspond to the same portion or window of a cardiac cycle. Further, signals from a first electrode and from a second electrode located proximate the first electrode may be compared to determine whether one or both of the electrodes are effective.

公开(公告)号：US10004906B2

公开(公告)日：2018-06-26

申请号：US14801049

申请日：2015-07-16

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Juan Du ,  Saul E Greenhut ,  Michael T Hemming

IPC: A61B5/00 ,  A61N1/368 ,  A61B5/0452 ,  A61N1/375 ,  A61N1/365 ,  A61B5/042 ,  A61N1/362

CPC classification number: A61N1/3682 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/04525 ,  A61B5/7246 ,  A61B5/7285 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/3756

Abstract: A medical device and medical device system for controlling delivery of therapeutic stimulation pulses that includes a sensing device to sense a cardiac signal and emit a trigger signal in response to the sensed cardiac signal, a therapy delivery device to receive the trigger signal and deliver therapy to the patient in response to the emitted trigger signal, and a processor positioned within the sensing device, the processor configured to determine whether the sensed cardiac signal exceeds a possible P-wave threshold, compare a portion of the sensed cardiac signal to a P-wave template having a sensing window having a length less than a width of the P-wave, confirm an occurrence of a P-wave signal in response to the comparing, emit the trigger signal in response to the occurrence of a P-wave signal being confirmed, and inhibit delivery of the emitting signal in response to the occurrence of a P-wave signal not being confirmed.

公开(公告)号：US09981136B2

公开(公告)日：2018-05-29

申请号：US14216100

申请日：2014-03-17

Applicant: Medtronic, Inc.

Inventor： Robert W Stadler ,  Subham Ghosh

IPC: A61N1/00 ,  A61N1/37 ,  A61B5/046 ,  A61N1/368 ,  A61N1/362

CPC classification number: A61N1/371 ,  A61B5/046 ,  A61N1/3622 ,  A61N1/3624 ,  A61N1/3684 ,  A61N1/3716

Abstract: The present disclosure relates to cardiac evoked response detection and, more particularly, reducing polarization effects in order to detect an evoked response following delivery of a stimulation pulse. An implantable medical device (IMD) is configured to deliver a ventricular pacing pulse. A signal is sensed in response to the ventricular pacing stimulus. A window is placed over the sensed signal to obtain a set of data from the signal after a paced event. The set of data extracted from the sensed signal comprises a maximum amplitude, a maximum time associated with the maximum amplitude, a minimum amplitude, and a minimum time associated with the minimum amplitude. Responsive to processing the extracted data, the window is delayed to avoid polarization effects. A determination is then made as to whether the ventricular pacing stimulus is capturing the paced ventricle in response to determining whether the maximum time is greater than the minimum time.

公开(公告)号：US09974457B2

公开(公告)日：2018-05-22

申请号：US14635498

申请日：2015-03-02

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey M. Gillberg ,  Robert W. Stadler

IPC: G06G7/48 ,  A61B5/04 ,  A61B5/0452 ,  A61B5/05 ,  A61B5/02 ,  A61B5/0402 ,  A61B5/0408 ,  A61N1/04 ,  A61N1/362 ,  A61N1/368 ,  A61B5/00 ,  A61B5/044

CPC classification number: A61B5/04012 ,  A61B5/02 ,  A61B5/0402 ,  A61B5/04085 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/05 ,  A61B5/742 ,  A61N1/0476 ,  A61N1/0484 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684

Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.

公开(公告)号：US09877789B2

公开(公告)日：2018-01-30

申请号：US13916353

申请日：2013-06-12

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61B5/00 ,  A61B19/00 ,  A61B6/00 ,  A61N1/372 ,  A61B6/12 ,  A61B5/0408 ,  A61N1/362 ,  A61N1/04 ,  A61N1/368 ,  A61B5/0452 ,  A61B5/04 ,  A61B5/044 ,  A61B5/042 ,  A61B5/055 ,  A61B90/00

CPC classification number: A61B34/10 ,  A61B5/0044 ,  A61B5/04012 ,  A61B5/04085 ,  A61B5/0422 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/055 ,  A61B5/489 ,  A61B5/6805 ,  A61B5/6823 ,  A61B5/686 ,  A61B5/743 ,  A61B5/7435 ,  A61B6/12 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/481 ,  A61B6/486 ,  A61B6/503 ,  A61B6/504 ,  A61B2090/3966 ,  A61B2562/043 ,  A61B2562/046 ,  A61B2576/023 ,  A61N1/0484 ,  A61N1/3627 ,  A61N1/368 ,  A61N1/372 ,  A61N1/37247

Abstract: Systems, methods, and interfaces are described herein for assisting in noninvasive location selection for an implantable electrode for use in cardiac therapy. Mechanical motion information and surrogate electrical activation times may be used to identify one or more candidate site regions.

公开(公告)号：US20170326368A1

公开(公告)日：2017-11-16

申请号：US15668945

申请日：2017-08-04

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Robert W. Stadler

IPC: A61N1/368 ,  A61N1/362 ,  A61N1/365

CPC classification number: A61N1/3682 ,  A61N1/3622 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/36592 ,  A61N1/3684

Abstract: Methods and/or devices may be configured to monitor ventricular activation times and modify an atrioventricular delay (AV delay) based on the monitored ventricular activation times. Further, the methods and/or devices may determine whether the AV delay should be modified based on the measured activation times before modifying the AV delay.

公开(公告)号：US09782094B2

公开(公告)日：2017-10-10

申请号：US14815478

申请日：2015-07-31

Applicant: Medtronic, Inc.

Inventor： Juan Du ,  Subham Ghosh ,  Jeffrey M Gillberg

IPC: A61B5/00 ,  A61B5/04 ,  A61B5/0408 ,  A61B5/0456 ,  A61N1/365

CPC classification number: A61B5/04012 ,  A61B5/04085 ,  A61B5/0456 ,  A61B5/6823 ,  A61B5/7221 ,  A61B5/7239 ,  A61B5/7435 ,  A61N1/36507

Abstract: A system and associated method is disclosed for determining whether a signal is ambiguous. The system comprises a plurality of electrodes configured to be located proximate tissue of a patient. A display apparatus comprises a graphical user interface configured to present information to a user. A computing apparatus is coupled to the electrode apparatus. The computing apparatus is configured to calculate a first derivative of a signal acquired from the electrodes, determine a first minimum from the first derivative, determine a second minimum from the second derivative and a second index within a window, calculate a ratio of the first and second derivatives, calculate a difference between a first and second index. In response to determining the ratio and the difference between the first and second index, the display apparatus displays whether the signal is ambiguous.

公开(公告)号：US09776009B2

公开(公告)日：2017-10-03

申请号：US14220733

申请日：2014-03-20

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Vincent Splett

IPC: A61N1/00 ,  A61N1/37 ,  A61B5/04 ,  A61B5/11 ,  A61N1/372 ,  A61B5/00 ,  A61B5/0408

CPC classification number: A61N1/3702 ,  A61B5/04001 ,  A61B5/04012 ,  A61B5/04085 ,  A61B5/1107 ,  A61B5/6823 ,  A61B5/7235 ,  A61B5/7267 ,  A61B5/743 ,  A61N1/37247

Abstract: Systems, methods, and graphical user interfaces are described herein for non-invasively detecting phrenic nerve stimulation during cardiac pacing therapy. Phrenic nerve stimulation information may be generated for one or more electrical pacing vectors at one or more power configurations. The phrenic nerve stimulation information may be displayed to a user for use in configuring and/or evaluating cardiac pacing therapy.

公开(公告)号：US09764143B2

公开(公告)日：2017-09-19

申请号：US14703348

申请日：2015-05-04

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey Gillberg

IPC: A61N1/36 ,  A61N1/368 ,  A61N1/372 ,  A61B5/00 ,  A61B5/0408 ,  A61B5/0452 ,  A61N1/365

CPC classification number: A61N1/3684 ,  A61B5/04085 ,  A61B5/0452 ,  A61B5/6805 ,  A61B5/7282 ,  A61N1/36514 ,  A61N1/3682 ,  A61N1/37247

Abstract: Systems and methods are described herein for assisting a user in identification of interventricular (V-V) delay for cardiac therapy. The systems and methods may monitor electrical activity of a patient using external electrode apparatus to provide electrical heterogeneity information for a plurality of different V-V intervals and may identify a V-V interval based on the electrical heterogeneity information.

公开(公告)号：US09757567B2

公开(公告)日：2017-09-12

申请号：US15176958

申请日：2016-06-08

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Robert W Stadler

IPC: A61N1/365 ,  A61N1/368 ,  A61N1/362

CPC classification number: A61N1/3682 ,  A61N1/3622 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/36592 ,  A61N1/3684

Abstract: Methods and/or devices may be configured to monitor ventricular activation times and modify an atrioventricular delay (AV delay) based on the monitored ventricular activation times. Further, the methods and/or devices may determine whether the AV delay should be modified based on the measured activation times before modifying the AV delay.