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公开(公告)号：US20120134948A1
公开(公告)日：2012-05-31
申请号：US13389115
申请日：2010-07-19
申请人： Oliver Springer , Peter Muss , Peter Lersch , Ursula Maczkiewitz , Mike Farwick
发明人： Oliver Springer , Peter Muss , Peter Lersch , Ursula Maczkiewitz , Mike Farwick
IPC分类号： A61K8/43 , A61K31/155 , A61Q15/00 , A01P1/00 , A61P31/00 , A61P31/04 , A01N37/52 , C07C279/08 , A61P17/10
CPC分类号： A61K31/155 , A01N47/44 , A61K8/43 , A61K9/0014 , A61Q15/00 , A61Q17/005 , A01N31/02 , A01N33/12 , A01N43/90 , A01N59/16 , A01N2300/00
摘要： The present invention relates to the use of at least one ether guanidine of the general formula (I) and/or of a salt or hydrate thereof, in which R1═—CH2—CH2—CH2—O—R3, where R3 is a linear or branched hydrocarbon radical having 6 to 22 carbon atoms, and R2═H or an optionally branched hydrocarbon radical which has 1 to 22 C atoms and which optionally comprises double bonds, for reducing the growth of microorganisms, and to cosmetic and pharmaceutical formulations comprising at least one ether guanidine of the general formulae (I).
摘要翻译： 本发明涉及至少一种通式（I）和/或其盐或水合物的醚胍，其中R 1 = -CH 2 -CH 2 -CH 2 -O-R 3，其中R 3是直链的 或具有6至22个碳原子的支链烃基，以及R2 = H或具有1至22个C原子且任选包含双键的任选支化的烃基，用于减少微生物的生长，以及包含在 至少一种通式（I）的醚胍。
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公开(公告)号：US20100184733A1
公开(公告)日：2010-07-22
申请号：US12445365
申请日：2006-10-13
申请人： Cornelis Gerrit Nijs Korevaar , Mike Farwick , Juergen Meyer , Peter Lersch , Wilma Reidick , Christian Weitemeyer
发明人： Cornelis Gerrit Nijs Korevaar , Mike Farwick , Juergen Meyer , Peter Lersch , Wilma Reidick , Christian Weitemeyer
IPC分类号： A61K31/575 , A61P17/02
摘要： The invention discloses skin treatment compositions consisting essentially of a mixture of ceramides, cholesterol, free fatty acids—the mixture being able to mimic skin identical lamellar structures—and nonionic emulsifiers. These compositions are liquid and pumpable at room temperature which means that they can be incorporated easily into cosmetic formulations with no need for heating. Furthermore, the skin treatment compositions allow the stable inclusion of long-chain ceramides into oil-in-water emulsions as well as into water-in-oil emulsions. Inclusion of short chain ceramides that can act as dermatological regulators did not affect the lamellar lipid organization. The skin treatment compositions are claimed as well as their use in cosmetic and dermatological formulations.
摘要翻译： 本发明公开了皮肤治疗组合物，其基本上由神经酰胺，胆固醇，游离脂肪酸的混合物组成 - 混合物能够模拟皮肤相同的层状结构 - 和非离子乳化剂。 这些组合物在室温下是液体和可泵送的，这意味着它们可以容易地并入化妆品配方中而不需要加热。 此外，皮肤处理组合物允许将长链神经酰胺稳定地包含在水包油乳液中以及油包水乳液中。 包含可用作皮肤调节剂的短链神经酰胺不影响层状脂质组织。 要求皮肤治疗组合物以及它们在化妆品和皮肤病学制剂中的用途。
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63.发明申请公开(公告)号：US20100136130A1
公开(公告)日：2010-06-03
申请号：US12596401
申请日：2008-04-15
申请人： Matthias Seiler , Martin Haneke , Henning Marckmann , Stephan Pilz , Muhammad Irfan , Saskia Klee-Laquai , Geoffrey Hills , Mike Farwick , Peter Lersch , Axel Kobus
发明人： Matthias Seiler , Martin Haneke , Henning Marckmann , Stephan Pilz , Muhammad Irfan , Saskia Klee-Laquai , Geoffrey Hills , Mike Farwick , Peter Lersch , Axel Kobus
IPC分类号： A61K36/736 , A61K9/14 , A61P43/00
CPC分类号： A61K36/00
摘要： The present invention relates to a preparation comprising at least one encapsulation material and at least one bioactive natural substance, which bioactive natural substance can be released from the preparation in a controlled manner, wherein the encapsulation material comprises at least one glyceride with a melting point of at least 35° C. and additionally at least one polymer with polyester units, which has a melting temperature of at least 30° C. and a viscosity in the range from 50 mPa*s to 250 Pa*s, measured by means of rotational viscometry at 110° C. The present invention further describes processes for producing the preparation of the invention, as well as preferred uses.
摘要翻译： 本发明涉及包含至少一种包封材料和至少一种生物活性天然物质的制剂，所述生物活性天然物质可以以受控的方式从所述制剂中释放，其中所述包封材料包含至少一种甘油酯，其熔点为 至少35℃，另外具有至少一种具有聚酯单元的聚合物，其具有至少30℃的熔融温度和在50mPa * s至250Pa * s范围内的粘度，其通过旋转 本发明还描述了制备本发明制剂的方法以及优选的用途。
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公开(公告)号：US20080249073A1
公开(公告)日：2008-10-09
申请号：US12135462
申请日：2008-06-09
申请人： Mike Farwick , Anthony V. Rawlings
发明人： Mike Farwick , Anthony V. Rawlings
IPC分类号： A61K31/606 , A61P17/00
摘要： This invention relates to a cosmetic composition comprising: a) Salicyloyl-sphingoidbases and/or derivatives thereof and b) a dermatologically acceptable carrier for treating and/or preventing cellulitic skin by increasing dermal structural proteins (collagen and fibrillin) and reducing the levels of MMP-1 activity.
摘要翻译： 本发明涉及化妆品组合物，其包含：a）水杨基 - 类鞘氨醇碱和/或其衍生物，和b）通过增加皮肤结构蛋白（胶原和纤维蛋白）并降低MMP的水平来治疗和/或预防纤维素皮肤的皮肤病学可接受的载体 -1活动。
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公开(公告)号：US20080145320A1
公开(公告)日：2008-06-19
申请号：US11939876
申请日：2007-11-14
IPC分类号： A61K8/44 , C07C235/00 , A01N37/18 , A61Q15/00 , A61P17/10 , A61Q11/00 , A01P1/00 , A61K31/164
CPC分类号： A61Q11/00 , A01N37/36 , A61K8/42 , A61K8/45 , A61K8/86 , A61Q5/006 , A61Q15/00 , A61Q19/00 , C07C235/06
摘要： Compounds of the general formula and to the use thereof for controlling microorganisms are provided.
摘要翻译： 提供通式的化合物及其用于控制微生物的用途。
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公开(公告)号：US20070003509A1
公开(公告)日：2007-01-04
申请号：US11479237
申请日：2006-06-30
申请人： Mike Farwick , Anthony Rawlings
发明人： Mike Farwick , Anthony Rawlings
IPC分类号： A61K8/42
摘要： This invention relates to a cosmetic composition comprising: a) Salicyloyl-sphingoidbases and/or derivatives thereof, and b) a dermatologically acceptable carrier for treating and/or preventing cellulitic skin by increasing dermal structural proteins (collagen and fibrillin) and reducing the levels of MMP-1 activity.
摘要翻译： 本发明涉及一种化妆品组合物，其包含：a）油酰基 - 类鞘氨醇碱和/或其衍生物，和b）皮肤病学上可接受的载体，用于通过增加皮肤结构蛋白（胶原和纤维蛋白）和降低纤维蛋白原的水平来治疗和/或预防纤维素皮肤 MMP-1活性。
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公开(公告)号：US09655934B2
公开(公告)日：2017-05-23
申请号：US14128244
申请日：2012-06-14
申请人： Yvonne Schiemann , Mike Farwick , Thomas Haas , Mirja Wessel
发明人： Yvonne Schiemann , Mike Farwick , Thomas Haas , Mirja Wessel
IPC分类号： A61K36/06 , A61K36/062 , A61K36/064 , A61K8/99 , A61Q19/00 , C12P1/02 , A23L33/145
CPC分类号： A61K36/064 , A23L33/145 , A23V2002/00 , A61K8/99 , A61K36/06 , A61Q19/00 , C12P1/02 , A23V2200/318 , A23V2250/218
摘要： The invention relates to a method for producing a dermatologically active yeast extract, comprising the following steps: providing a preculture of the yeast cells, culturing the cells for at least fifteen minutes at a pH of 1.8-4, harvesting the cells and lysing the cells, and a yeast extract produced thereby and products comprising said yeast extract.
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公开(公告)号：US09610232B2
公开(公告)日：2017-04-04
申请号：US14236696
申请日：2012-07-04
申请人： Mike Farwick , Tim Koehler , Matthias Mentel
发明人： Mike Farwick , Tim Koehler , Matthias Mentel
IPC分类号： A61K8/41 , A61K8/34 , A61Q19/00 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q11/00 , A61Q17/04 , A61Q19/10
CPC分类号： A61K8/41 , A61Q5/00 , A61Q5/002 , A61Q5/006 , A61Q5/02 , A61Q5/12 , A61Q11/00 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/008 , A61Q19/10
摘要： The invention relates to the use of sphinganine for improving the visual appearance of skin and hair, for caring for, for protecting and/or for stimulating the growth of skin and hair.
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公开(公告)号：US20160184204A1
公开(公告)日：2016-06-30
申请号：US14908195
申请日：2014-07-01
申请人： Tim KÖHLER , Mike FARWICK , Matthias MENTEL , Peter LERSCH
发明人： Tim Kohler , Mike Farwick , Matthias Mentel , Peter Lersch
CPC分类号： A61K8/41 , A61K8/361 , A61K8/44 , A61K8/4946 , A61K8/4953 , A61K8/63 , A61K8/673 , A61K31/133 , A61K31/191 , A61K31/198 , A61K31/201 , A61K31/205 , A61K31/4168 , A61K31/4188 , A61K31/506 , A61K31/522 , A61Q5/12 , A61Q7/00 , A61K2300/00
摘要： The present invention relates to formulations comprising A) sphinganine and B) at least one active ingredient selected from the group creatine, creatinine, caffeine, carnitine, biotin, arjunolic acid, xymenynic acid, minoxidil, arginine and derivatives thereof.
摘要翻译： 本发明涉及包含A）鞘氨醇和B）至少一种选自肌酸，肌酸酐，咖啡因，肉毒碱，生物素，丙二酸，肉豆蔻酸，米诺地尔，精氨酸及其衍生物的活性成分的制剂。
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公开(公告)号：US20140127257A1
公开(公告)日：2014-05-08
申请号：US14128244
申请日：2012-06-14
申请人： Yvonne Schiemann , Mike Farwick , Thomas Haas , Mirja Wessel
发明人： Yvonne Schiemann , Mike Farwick , Thomas Haas , Mirja Wessel
IPC分类号： A61K36/064 , C12P1/02 , A61K36/06
CPC分类号： A61K36/064 , A23L33/145 , A23V2002/00 , A61K8/99 , A61K36/06 , A61Q19/00 , C12P1/02 , A23V2200/318 , A23V2250/218
摘要： The invention relates to a method for producing a dermatologically active yeast extract, comprising the following steps: providing a preculture of the yeast cells, culturing the cells for at least fifteen minutes at a pH of 1.8-4, harvesting the cells and lysing the cells, and a yeast extract produced thereby and products comprising said yeast extract.
摘要翻译： 本发明涉及一种生产皮肤病学活性酵母提取物的方法，包括以下步骤：提供酵母细胞的预培养，在1.8-4的pH下培养细胞至少15分钟，收获细胞并裂解细胞 ，以及由此产生的酵母提取物和包含所述酵母提取物的产品。
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