公开(公告)号：US20110257751A1

公开(公告)日：2011-10-20

申请号：US13153136

申请日：2011-06-03

申请人： Michael C. Sherman ,  Samuel M. Shaolian

发明人： Michael C. Sherman ,  Samuel M. Shaolian

IPC分类号： A61F2/44

CPC分类号： A61F2/44 ,  A61F2/30965 ,  A61F2/4465 ,  A61F2/4684 ,  A61F2002/3008 ,  A61F2002/30369 ,  A61F2002/30411 ,  A61F2002/30507 ,  A61F2002/30525 ,  A61F2002/3055 ,  A61F2002/30596 ,  A61F2002/30601 ,  A61F2002/30677 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30843 ,  A61F2002/30845 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2250/0098 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00179 ,  A61F2310/00329

摘要： Embodiments of the invention include expandable, implantable devices and methods having internally contained expansion mechanisms. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

摘要翻译： 本发明的实施例包括具有内部包含的扩张机构的可扩展的可植入装置和方法。 设备线性扩展以在解剖结构之间或之间提供牢固的固定。 在一些实施例中，植入物代替脊柱的一个或多个椎体。

公开(公告)号：US08012187B2

公开(公告)日：2011-09-06

申请号：US11377991

申请日：2006-03-17

申请人： Michael C. Sherman ,  Fred J. Molz, IV

发明人： Michael C. Sherman ,  Fred J. Molz, IV

IPC分类号： A61B17/56

CPC分类号： A61B17/70 ,  A61B17/025 ,  A61B17/7035 ,  A61B17/7089 ,  A61B17/866 ,  A61B2017/0256 ,  A61B2017/3447 ,  A61B2017/564 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/4455

摘要： Techniques for spinal surgery include accessing at least one vertebral element of the spinal column. At least one loading member is engaged to the at least one vertebral element. The loading member is allowed to integrate with the bony structure of the vertebral element over time. The integrated loading member is accessed in a second surgical procedure, and can be loaded and/or attached to a construct.

摘要翻译： 用于脊柱手术的技术包括进入脊柱的至少一个椎体元件。 至少一个装载构件接合到所述至少一个椎骨元件。 随着时间的推移，允许装载构件与椎骨元件的骨结构整合。 在第二外科手术中访问整合的加载构件，并且可以将其加载和/或附接到构造。

公开(公告)号：US20110202091A1

公开(公告)日：2011-08-18

申请号：US13097622

申请日：2011-04-29

申请人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

发明人： Hai H. Trieu ,  Jeff R. Justis ,  Troy D. Drewry ,  Michael C. Sherman ,  Bradley J. Coates ,  Bradley T. Estes

IPC分类号： A61B17/88 ,  A61B17/80

CPC分类号： A61B17/8042 ,  A61B17/7059 ,  A61B17/8052 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0811

摘要： This invention relates to orthopedic implants and to methods of treating bone defects. More specifically, but not exclusively, the present invention is directed to non-metallic implants and to methods for intra-operative assembly and fixation of orthopedic implants to facilitate medical treatment. The non-metallic implant assembly can be secured to underlying tissue by a fastener, such as a bone screw, that is capable of swelling on contact with fluid in the underlying tissue. Alternatively, the non-metallic implant assembly can be assembled intra-operatively using a fastener that is adhesively bonded to a bone plate or the bone plate can be deformed using heat, force, or solvents to inhibit withdrawal of the fastener. In preferred embodiments, both the fastener and the bone plate are formed of biodegradable material.

摘要翻译： 本发明涉及矫形植入物和治疗骨缺损的方法。 更具体地但非唯一地，本发明涉及非金属植入物以及用于手术中组装和固定矫形植入物以方便医疗的方法。 非金属植入物组件可以通过紧固件（例如骨螺钉）固定到下面的组织上，该紧固件能够在与下面的组织中的流体接触时膨胀。 或者，非金属植入物组件可以使用粘合剂粘合到骨板上的紧固件在手术中组装，或者骨板可以使用热，力或溶剂变形以阻止紧固件的拉出。 在优选实施例中，紧固件和骨板都是由可生物降解的材料形成的。

公开(公告)号：US07771476B2

公开(公告)日：2010-08-10

申请号：US11643489

申请日：2006-12-21

申请人： Jeff R. Justis ,  Hai H. Trieu ,  Dimitri Protopsaltis ,  Michael C. Sherman

发明人： Jeff R. Justis ,  Hai H. Trieu ,  Dimitri Protopsaltis ,  Michael C. Sherman

IPC分类号： A61F2/44

CPC分类号： A61B17/866 ,  A61B17/7013 ,  A61B17/7032 ,  A61B17/7049 ,  A61B17/80 ,  A61B17/8605 ,  A61B17/8625 ,  A61F2/441 ,  A61F2/4425 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/302 ,  A61F2002/30225 ,  A61F2002/30545 ,  A61F2002/30556 ,  A61F2002/30583 ,  A61F2002/30677 ,  A61F2002/30884 ,  A61F2002/3092 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/465 ,  A61F2210/0004 ,  A61F2210/0085 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2250/0009 ,  A61F2250/001

摘要： An orthopedic implant device is non-rigid, i.e., flexible and/or malleable, in a first form for insertion into a desired in vivo site, and then transformable into a rigid, or hardened, form for providing a load-bearing function or providing other structural and/or mechanical function after implant. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after insertion to an in vivo location as a result of application of a cure-initiating energy to the material prior to insertion. Related methods and kits are also provided.

摘要翻译： 整形外科植入物装置是非刚性的，即柔性和/或可延展的，以第一形式插入所需的体内部位，然后可变形成刚性或硬化的形式，以提供承载功能或提供 植入后的其他结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在插入到体内位置之后以第二种形式刚性化，这是由于在插入之前向该材料施加固化引发能量。 还提供了相关方法和试剂盒。

公开(公告)号：US07699879B2

公开(公告)日：2010-04-20

申请号：US10689961

申请日：2003-10-21

申请人： Michael C. Sherman ,  Jeff R. Justis

发明人： Michael C. Sherman ,  Jeff R. Justis

IPC分类号： A61B17/80

CPC分类号： A61B17/7032 ,  A61B17/6491 ,  A61B17/68 ,  A61B17/686 ,  A61B17/7007 ,  A61B17/7059 ,  A61B17/8004 ,  A61B17/8042 ,  A61B2017/00004 ,  Y10S606/908

摘要： The present invention generally relates to orthopedic devices and methods for treating bone defects. The orthopedic devices can provide sufficient support to the bone defect while allowing bone ingrowth and minimizing the risk to stress shield and/or pseudo-arthrodesis. The bone fixation devices include a biodegradable material or component that further resists relative motion of attached bones and allows the device to gradually transfer at least some load from the device to the growing bone structure in vivo and permitting an increase in the relative motion of bones attached to the device.

摘要翻译： 本发明一般涉及矫形装置和治疗骨缺损的方法。 整形外科设备可以为骨缺损提供足够的支撑，同时允许骨向内生长并最小化应力屏蔽和/或伪关节固定的风险。 骨固定装置包括进一步抵抗附着骨的相对运动的可生物降解的材料或组分，并允许该装置在体内逐渐将至少一些载荷从装置转移到生长的骨骼结构，并允许增加附着的骨骼的相对运动 到设备。

公开(公告)号：US20090222099A1

公开(公告)日：2009-09-03

申请号：US12039021

申请日：2008-02-28

申请人： Mingyan Liu ,  Hai H. Trieu ,  Michael C. Sherman

发明人： Mingyan Liu ,  Hai H. Trieu ,  Michael C. Sherman

IPC分类号： A61F2/44

CPC分类号： A61F2/442 ,  A61F2002/30016 ,  A61F2002/30069 ,  A61F2002/444 ,  A61F2250/0019 ,  A61F2310/00011 ,  A61F2310/00179

摘要： An intervertebral disc augmentation implant for implantation between a pair of vertebral bodies comprises an elastically deformable outer casing having at least one thickness dimension and a core member having isotropic material properties. The core member is entirely encased within the outer casing and has a height dimension along an axis defined by the pair of vertebral bodies. The modulus of elasticity of the core member is greater than a modulus of elasticity of the outer casing, and the height dimension of the core member is greater than the at least one thickness dimension of the outer casing.

摘要翻译： 用于在一对椎体之间植入的椎间盘增大植入物包括具有至少一个厚度尺寸的可弹性变形的外壳和​​具有各向同性材料性质的芯构件。 芯构件完全包裹在外壳内，并且沿着由一对椎体限定的轴线具有高度尺寸。 芯构件的弹性模量大于外壳的弹性模量，并且芯构件的高度尺寸大于外壳的至少一个厚度尺寸。

公开(公告)号：US07556630B2

公开(公告)日：2009-07-07

申请号：US11499145

申请日：2006-08-04

申请人： Fred J. Molz, IV ,  Michael C. Sherman ,  Troy D. Drewry

发明人： Fred J. Molz, IV ,  Michael C. Sherman ,  Troy D. Drewry

IPC分类号： A61B17/56

CPC分类号： A61B17/8869 ,  A61B17/2812 ,  A61B17/282 ,  A61B17/88

摘要： An instrument for tensioning a flexible elongate member in a surgical procedure includes a tensioning mechanism engageable to a portion of the flexible elongate member and operable to apply a tensioning force to the elongate member. The instrument includes a distal end portion at a distal end of the tensioning mechanism that is adapted to allow orientation of the elongate member in a first direction for implantation and to allow the instrument to extend transversely to the implantation orientation during application of a tensioning force. The distal end portion can also include a receptacle to receive a structure at the surgical site to facilitate positioning of the distal end portion at the desired location.

摘要翻译： 用于在外科手术过程中张紧柔性细长构件的装置包括可与柔性细长构件的一部分接合并可操作以向细长构件施加张紧力的张紧机构。 仪器包括在张紧机构的远端处的远端部分，其适于允许细长构件沿着第一方向进行植入，并且允许器械在施加张紧力期间横向于植入取向延伸。 远端部分还可以包括用于在外科手术部位处接收结构的容器，以便于将远端部分定位在所需位置。

公开(公告)号：US20080154367A1

公开(公告)日：2008-06-26

申请号：US11643177

申请日：2006-12-21

申请人： Jeff R. Justis ,  Dimitri Protopsaltis ,  Hai H. Trieu ,  Michael C. Sherman

发明人： Jeff R. Justis ,  Dimitri Protopsaltis ,  Hai H. Trieu ,  Michael C. Sherman

IPC分类号： A61F2/02 ,  A61B17/58

CPC分类号： A61B17/7032 ,  A61B17/7013 ,  A61B17/80 ,  A61B17/8085 ,  A61B17/866 ,  A61B2017/00004 ,  A61B2017/00831 ,  A61F2/441 ,  A61F2/442 ,  A61F2/4425 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/30062 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30649 ,  A61F2002/30841 ,  A61F2002/30884 ,  A61F2210/0004 ,  A61F2210/0085

摘要： A device is provided that is non-rigid, i.e., flexible and/or malleable, in a first form, and then transformable after insertion to an in vivo site into a rigid, or hardened, form; a cure-initiating energy is applied to the device; and the device is then positioned in the in vivo site where it hardens to provide a load-bearing function or other structural and/or mechanical function. The device includes a biocompatible sheath and a curable material sealed within the sheath. The curable material is provided in a first form that provides flexibility to the device and is structured to rigidize in a second form after application of a quantity of an initiating energy to the material.

摘要翻译： 提供了以第一种形式是非刚性的，即柔性的和/或可延展的装置，然后在插入到体内部位之后可变形为刚性或硬化的形式; 对装置施加固化起始能量; 然后将该装置定位在体内部位，在那里其硬化以提供承载功能或其它结构和/或机械功能。 该装置包括生物相容护套和密封在护套内的可固化材料。 可固化材料以提供该装置的柔性的第一形式提供，并且被构造成在将一定量的起始能量施加到材料之后以第二形式刚性化。

公开(公告)号：US20080058932A1

公开(公告)日：2008-03-06

申请号：US11493783

申请日：2006-07-26

申请人： Hai H. Trieu ,  Dimitri Protopsaltis ,  Jeff R. Justis ,  Michael C. Sherman

发明人： Hai H. Trieu ,  Dimitri Protopsaltis ,  Jeff R. Justis ,  Michael C. Sherman

IPC分类号： A61F2/44

CPC分类号： A61F2/4425 ,  A61B17/7013 ,  A61B17/7031 ,  A61B17/7059 ,  A61B17/8085 ,  A61B17/864 ,  A61B2017/00831 ,  A61F2/44 ,  A61F2/441 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/3009 ,  A61F2002/302 ,  A61F2002/30537 ,  A61F2002/30563 ,  A61F2002/30565 ,  A61F2002/30583 ,  A61F2002/30586 ,  A61F2002/30884 ,  A61F2002/444 ,  A61F2210/0004 ,  A61F2210/0085 ,  A61F2230/0065 ,  A61F2250/0004 ,  A61F2250/0091

摘要： Orthopedic devices include a body having an internal chamber housing a curable material. At least a portion of the body provides a barrier member structured to transmit an energy source therethrough to contact the curable material disposed in the internal chamber. The curable material is provided in a first form that provides flexibility to the body and is structured to rigidize in a second form when exposed to the energy source.

摘要翻译： 矫形装置包括具有容纳可固化材料的内室的主体。 身体的至少一部分提供了阻挡构件，其构造成透过其中的能量源以与设置在内部腔室中的可固化材料接触。 可固化材料以第一形式提供，其向身体提供柔性，并且被构造成当暴露于能量源时以第二形式刚性化。

公开(公告)号：US07094240B2

公开(公告)日：2006-08-22

申请号：US10339837

申请日：2003-01-10

申请人： Fred J. Molz, IV ,  Michael C. Sherman ,  Troy D. Drewry

发明人： Fred J. Molz, IV ,  Michael C. Sherman ,  Troy D. Drewry

IPC分类号： A61B17/56

CPC分类号： A61B17/8869 ,  A61B17/2812 ,  A61B17/282 ,  A61B17/88

摘要： An instrument for tensioning a flexible elongate member in a surgical procedure includes a tensioning mechanism engageable to a portion of the flexible elongate member and operable to apply a tensioning force to the elongate member. The instrument includes a distal end portion at a distal end of the tensioning mechanism that is adapted to allow orientation of the elongate member in a first direction for implantation and to allow the instrument to extend transversely to the implantation orientation during application of a tensioning force. The distal end portion can also include a receptacle to receive a structure at the surgical site to facilitate positioning of the distal end portion at the desired location.