公开(公告)号：US07579263B2

公开(公告)日：2009-08-25

申请号：US10935228

申请日：2004-09-08

Applicant: Sang Han ,  Qiming Li

Inventor： Sang Han ,  Qiming Li

IPC: H01L21/20 ,  C30B25/02

CPC classification number: H01L21/0245 ,  H01L21/02381 ,  H01L21/02521 ,  H01L21/02532 ,  H01L21/02642 ,  H01L21/02647

Abstract: A method of forming a virtually defect free lattice mismatched nanoheteroepitaxial layer is disclosed. The method includes forming an interface layer on a portion of a substrate. A plurality of seed pads are then formed by self-directed touchdown by exposing the interface layer to a material comprising a semiconductor material. The plurality of seed pads, having an average width of about 1 nm to 10 nm, are interspersed within the interface layer and contact the substrate. An epitaxial layer is then formed by lateral growth of the seed pads over the interface layer.

Abstract translation: 公开了形成几乎无缺陷的晶格失配的纳米外延层的方法。 该方法包括在衬底的一部分上形成界面层。 然后通过将界面层暴露于包含半导体材料的材料，通过自我定向的触地来形成多个种子垫。 具有约1nm至10nm的平均宽度的多个种子垫分散在界面层内并与基底接触。 然后通过界面层上的种子垫的横向生长形成外延层。

公开(公告)号：US20090175557A1

公开(公告)日：2009-07-09

申请号：US12406730

申请日：2009-03-18

Applicant: OUSSEINI LANKOANDE ,  Majeed Hayat ,  Balu Santhanam

Inventor： OUSSEINI LANKOANDE ,  Majeed Hayat ,  Balu Santhanam

IPC: G06K9/40

CPC classification number: G06K9/0063 ,  G01S13/9035 ,  G06K9/40 ,  G06K9/4638 ,  G06T5/002 ,  G06T7/11 ,  G06T7/143 ,  G06T2207/10032 ,  G06T2207/10132 ,  G06T2207/30004 ,  G06T2207/30181

Abstract: The present invention includes methods for the reduction of speckle noise in an image and methods for segmenting an image. Each of the methods disclosed herein includes steps for analyzing the uniformity of a pixel within a plurality of pixels forming a portion of the image and, based on the uniformity of the intensity of the plurality of pixels, adjusting and/or replacing the pixel in order to produce a speckle-noise reduced image, a segmented image, or a segmented and speckle-noise reduced image. The methods of the present invention can employ for example conditional probability density functions, nonlinear estimator functions, convex energy functions and simulated annealing algorithms in the performance of their respective steps.

Abstract translation: 本发明包括用于减少图像中的斑点噪声的方法和用于分割图像的方法。 本文公开的每种方法包括用于分析形成图像的一部分的多个像素内的像素的均匀性的步骤，并且基于多个像素的强度的均匀性，按顺序调整和/或替换像素 以产生斑点噪声缩小图像，分割图像或分割和斑点噪声缩小图像。 本发明的方法可以在其各自的步骤的执行中使用例如条件概率密度函数，非线性估计函数，凸能量函数和模拟退火算法。

公开(公告)号：US20090099087A1

公开(公告)日：2009-04-16

申请号：US12286933

申请日：2008-10-03

Applicant: Walter Kisiel ,  Hitendra S. Chand

Inventor： Walter Kisiel ,  Hitendra S. Chand

IPC: A61K38/17 ,  C12N5/02 ,  A61P35/04

CPC classification number: C07K14/8114 ,  A61K38/00

Abstract: A human Kunitz-type inhibitor polypeptide with enhanced antifibrinolytic activity, methods of making, and methods of use. The novel polypeptide is structurally similar to the KD1 domain of human tissue factor pathway inhibitor-2 (TFPI-2). In another aspect, methods of treating a subject afflicted with cancer or a precancerous condition are described. Generally, the method includes administering to a subject in need of treatment an effective amount of a polypeptide. In some embodiments, the polypeptide comprises a KD1 domain of human TFPI-2. In some embodiments, the polypeptide comprises human TFPI-2, itself. In certain embodiments, the polypeptide is administered in an amount effective to induce apoptosis in tumor cells.

Abstract translation: 具有增强的抗纤维蛋白溶解活性的人Kunitz型抑制剂多肽，制备方法和使用方法。 新型多肽在结构上类似于人组织因子途径抑制剂-2（TFPI-2）的KD1结构域。 另一方面，描述了治疗患有癌症或癌前病症的受试者的方法。 通常，该方法包括向需要治疗的受试者施用有效量的多肽。 在一些实施方案中，多肽包含人TFPI-2的KD1结构域。 在一些实施方案中，多肽本身包含人TFPI-2。 在某些实施方案中，以有效诱导肿瘤细胞凋亡的量施用多肽。

公开(公告)号：US20090069175A1

公开(公告)日：2009-03-12

申请号：US11873568

申请日：2007-10-17

Applicant: Elise Switzer ,  Plamen Atanassov ,  Abhaya Datye

Inventor： Elise Switzer ,  Plamen Atanassov ,  Abhaya Datye

IPC: B01J23/42 ,  B01J23/62

CPC classification number: H01M4/921

Abstract: An aerosol-assisted method for synthesis of nanostructured metallic electrocatalysts and the electrocatalysts formed thereby. The electrocatalyst may be formed from metals such as, but not limited to, platinum, platinum group metals, and binary and tertiary compositions thereof such as, for example, platinum-ruthenium and platinum-tin. The resulting unsupported electrocatalyst is homogenous and highly disperse.

Abstract translation: 用于合成纳米结构金属电催化剂的气溶胶辅助方法和由此形成的电催化剂。 电催化剂可以由金属形成，例如但不限于铂，铂族金属及其二元和三级组合物，例如铂 - 钌和铂 - 锡。 所得的无载体电催化剂是均匀的并且高度分散。

公开(公告)号：US20080315370A1

公开(公告)日：2008-12-25

申请号：US12200139

申请日：2008-08-28

Applicant: Seung-Chang Lee ,  Steven R. J. Brueck

Inventor： Seung-Chang Lee ,  Steven R. J. Brueck

IPC: H01L29/04

CPC classification number: H01L21/02642 ,  H01L21/02373 ,  H01L21/02387 ,  H01L21/02433 ,  H01L21/02609 ,  H01L33/007 ,  H01S5/0205

Abstract: Methods for forming {110} type facets on a (001) oriented substrate of Group III-V compounds and Group IV semiconductors using selective epitaxial growth is provided. The methods include forming a dielectric film on a (100) substrate. The dielectric film can then be patterned to expose a portion of the substrate and to form a substrate-dielectric film boundary substantially parallel to a direction. A {110} type sidewall facet can then be formed by epitaxially growing a semiconductor layer on the exposed portion of the substrate and the dielectric film.

Abstract translation: 提供了使用选择性外延生长在III-V族化合物和IV族半导体的（001）取向衬底上形成{110}型面的方法。 所述方法包括在（100）衬底上形成电介质膜。 然后可以对电介质膜进行构图以暴露衬底的一部分并且形成基本上平行于<110>方向的衬底 - 电介质膜边界。 然后可以通过在衬底和电介质膜的暴露部分上外延生长半导体层来形成{110}型侧壁面。

公开(公告)号：US20080311391A1

公开(公告)日：2008-12-18

申请号：US12134874

申请日：2008-06-06

Applicant: Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

Inventor： Gautam Gupta ,  Gabriel Lopez ,  Plamen Atanassov

IPC: B32B9/00 ,  B05D3/12

CPC classification number: A61K9/06 ,  A61K9/127 ,  Y10T428/265 ,  Y10T436/25

Abstract: The disclosure provides a simple and effective way of synthesizing robust organic-inorganic hybrid gels and ultra-thin films using vaporization of a gel precursor. The gels are synthesized at relatively low temperature allowing the activity of the immobilized species to be maintained. The disclosure provides robust, synthetic, selective, active and/or passive transport systems in the form of functional biologically active species and mechanisms for forming them. These systems allow selective and passive or active transport of ionic, molecular and biological species through the incorporation of functional biological molecules and biomolecular assemblies in a rigid matrix.

Abstract translation: 本公开提供了使用凝胶前体的蒸发来合成鲁棒的有机 - 无机杂化凝胶和超薄膜的简单而有效的方法。 凝胶在相对较低的温度下合成，允许保持固定化物质的活性。 本公开提供了功能性生物活性物质形式的强大的，合成的，选择性的，主动的和/或被动的运输系统和用于形成它们的机制。 这些系统通过将功能性生物分子和生物分子组装结合到刚性基质中来允许离子，分子和生物物质的选择性和被动或主动传递。

公开(公告)号：US20080225269A1

公开(公告)日：2008-09-18

申请号：US12016711

申请日：2008-01-18

Applicant: James L. Thomas ,  Wolfgang G. Rudolph ,  Xuejun Liu

Inventor： James L. Thomas ,  Wolfgang G. Rudolph ,  Xuejun Liu

IPC: G01J3/00 ,  G01B9/02

CPC classification number: G01J3/44 ,  G01J3/10 ,  G01N21/31 ,  G01N2021/3155 ,  G01N2021/3185

Abstract: The present invention includes a system and method for coherent imaging. The system of the present invention includes a light source adapted to provide coherent light to illuminate a sample resulting in optically mixed coherent signals and a detector adapted to receive the optically mixed coherent signals and produce an output signal in response thereto. The optically mixed coherent signals will be a set of sum and difference frequency combinations of the frequencies in the coherent light. A processor is connected to the detector and adapted to ratio a selected two of the optically mixed coherent signals in response to the output signal received by the detector and to generate an image in response to the ratioed optically mixed coherent signals, which can be displayed for a user.

Abstract translation: 本发明包括用于相干成像的系统和方法。 本发明的系统包括适于提供相干光以照亮产生光学混合相干信号的样本的光源，以及适于接收光学混合相干信号并响应于此产生输出信号的检测器。 光学混合的相干信号将是相干光中的频率的和和差频组合的集合。 处理器连接到检测器并且适于响应于由检测器接收的输出信号来比较所选择的两个光学混合相干信号，并且响应于比率的光学混合相干信号而产生图像，其可以显示为 一个用户

公开(公告)号：US07393391B2

公开(公告)日：2008-07-01

申请号：US10969341

申请日：2004-10-21

Applicant: Gabriel P. Lopez ,  Plamen B. Atanassov ,  Dmitri A. Brevnov ,  Marcos Barela

Inventor： Gabriel P. Lopez ,  Plamen B. Atanassov ,  Dmitri A. Brevnov ,  Marcos Barela

IPC: B01D53/22 ,  B01D71/06 ,  B01D67/00

CPC classification number: B01D69/02 ,  B01D67/0065 ,  B01D67/0079 ,  B01D67/0088 ,  B01D69/127 ,  C25D11/045 ,  C25D11/12 ,  C25D11/24

Abstract: Anisotropic hydrophobic/hydrophilic nanoporous membranes and methods of forming anisotropic hydrophobic/hydrophilic nanoporous membranes are disclosed. The method of forming the nanoporous membrane includes growing a nanoporous oxide film on a substrate. A nanoporous membrane having a top side and a bottom side can then be formed by partially separating the nanoporous oxide film from the substrate. A fluorocarbon film can be deposited on the top side of the nanoporous membrane by plasma polymerization. The disclosed anisotropic hydrophobic/hydrophilic nanoporous membranes can have extremely different hydrophobicity between the top side and the bottom side of the nanoporous membrane.

Abstract translation: 公开了各向异性疏水/亲水纳米多孔膜和形成各向异性疏水/亲水纳米多孔膜的方法。 形成纳米多孔膜的方法包括在衬底上生长纳米多孔氧化物膜。 然后可以通过从纳米孔氧化膜与基底部分分离而形成具有顶侧和底侧的纳米多孔膜。 氟碳膜可以通过等离子体聚合沉积在纳米多孔膜的顶侧。 所公开的各向异性疏水/亲水纳米孔膜可以在纳米多孔膜的顶侧和底侧之间具有非常不同的疏水性。

公开(公告)号：US07368084B2

公开(公告)日：2008-05-06

申请号：US11066843

申请日：2005-02-25

Applicant: Larry A. Sklar ,  Bruce S. Edwards ,  Frederick W. Kuckuck

Inventor： Larry A. Sklar ,  Bruce S. Edwards ,  Frederick W. Kuckuck

IPC: B32B5/02

CPC classification number: G01N15/1436 ,  B01L3/5085 ,  G01N15/1404 ,  G01N15/1459 ,  G01N21/6428 ,  G01N21/6486 ,  G01N35/0099 ,  G01N35/085 ,  G01N35/1095 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1413 ,  G01N2015/1477 ,  G01N2015/149 ,  G01N2021/6439 ,  G01N2201/06113 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/119163 ,  Y10T436/2575

Abstract: The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means for introducing a separation gas between each of the plurality of samples in the fluid flow stream; and means for selectively analyzing each of the plurality of samples for the particles. The present invention also provides a flow cytometry method employing such an apparatus.

公开(公告)号：US07332264B2

公开(公告)日：2008-02-19

申请号：US10373565

申请日：2003-02-26

Applicant: Dhaval Doshi ,  Hongyou Fan ,  Nicola Huesing ,  Alan Hurd ,  Charles Jeffrey Brinker

Inventor： Dhaval Doshi ,  Hongyou Fan ,  Nicola Huesing ,  Alan Hurd ,  Charles Jeffrey Brinker

IPC: G03F7/26

CPC classification number: G03F7/0047 ,  G03F7/075

Abstract: The present invention provides a mesoporous material comprising at least one region of mesoporous material patterned at a lithographic scale. The present invention also provides a method for forming a patterned mesoporous material comprising: coating a sol on a substrate to form a film, the sol comprising: at least one photoactivator generator, at least one material capable of being sol-gel processed; and exposing the film to light to form a patterned mesoporous material.

Abstract translation: 本发明提供一种介孔材料，其包括在光刻尺度上图案化的介孔材料的至少一个区域。 本发明还提供了一种用于形成图案化介孔材料的方法，包括：在基底上涂覆溶胶以形成膜，所述溶胶包括：至少一种光活化剂发生剂，至少一种能够进行溶胶 - 凝胶加工的材料; 并将该膜曝光以形成图案化的介孔材料。