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    Photodefined aperture plate and method for producing the same
    71.
    发明授权
    Photodefined aperture plate and method for producing the same 有权

    公开(公告)号：US10508353B2

    公开(公告)日：2019-12-17

    申请号：US15625639

    申请日：2017-06-16

    Applicant: Stamford Devices Ltd.

    Inventor： Hong Xu

    IPC: C25D7/00 ,  B41J2/16 ,  C25D5/02 ,  C25D5/10 ,  C25D1/00 ,  B05B17/00 ,  C25D3/38 ,  C25D3/46 ,  C25D3/48 ,  C25D3/54 ,  C25D5/34 ,  C25D5/48 ,  C25D5/54

    Abstract: In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.

    Nebulizer vibrating aperture plate drive frequency control and monitoring
    72.
    发明授权
    Nebulizer vibrating aperture plate drive frequency control and monitoring 有权

    公开(公告)号：US10449307B2

    公开(公告)日：2019-10-22

    申请号：US15933082

    申请日：2018-03-22

    Applicant: Stamford Devices Limited

    Inventor： Joseph Grehan ,  Niall Smith

    IPC: A61M11/00 ,  B05B17/06 ,  G01N29/22 ,  G01N29/42 ,  G06F19/00 ,  B05B17/00 ,  B06B1/02 ,  G16H20/13 ,  B05B15/14 ,  B05B12/00 ,  B05B12/08

    Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.

    AEROSOL GENERATOR
    73.
    发明申请
    AEROSOL GENERATOR 审中-公开

    公开(公告)号：US20190224709A1

    公开(公告)日：2019-07-25

    申请号：US16314830

    申请日：2017-06-29

    Applicant: Stamford Devices Limited

    Inventor： Patrick Martin KELLY ,  Joseph GREHAN ,  Finbarr MAGUIRE

    IPC: B05B17/00 ,  A61F9/00

    Abstract: An aperture plate 1 comprises an inlet surface 2 for receiving a liquid to be aerosolised, an outlet surface 3 and a plurality of apertures 4 extending therebetween. The apertures 4 are tapered from an inlet opening 10 at the inlet surface 2 to an outlet or exit opening 12. The aperture plate 1 is convex in the direction of the inlet openings 10 and concave in the direction of the exit openings 12. The aerosol exits on the concave side of the aperture plate. The aperture plate of the invention generates an aerosol plume which converges and is particularly suitable for application to the eye.

    AEROSOL GENERATOR
    76.
    发明申请
    AEROSOL GENERATOR 审中-公开

    公开(公告)号：US20170203319A1

    公开(公告)日：2017-07-20

    申请号：US15476242

    申请日：2017-03-31

    Applicant: Stamford Devices Limited

    Inventor： Brendan Hogan ,  Kieran HYLAND ,  Anthony REDMOND

    IPC: B05B17/00 ,  A61M11/00

    CPC classification number: B05B17/0646 ,  A61M11/001 ,  A61M11/005 ,  A61M15/0085

    Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.

    AEROSOL GENERATORS
    77.
    发明申请
    AEROSOL GENERATORS 审中-公开

    公开(公告)号：US20170136485A1

    公开(公告)日：2017-05-18

    申请号：US15358446

    申请日：2016-11-22

    Applicant: Stamford Devices Limited

    Inventor： Brendan Hogan ,  Daniela BUTAN ,  Seamus CLIFFORD ,  Michael POMEROY ,  Mark SOUTHERN ,  David SHEIL

    IPC: B05B17/00 ,  B05B17/06

    CPC classification number: B05B17/0646 ,  B05B15/18 ,  B05B17/06 ,  B05B17/0653 ,  B05B17/0669

    Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulisers, eliminates the risk of premature and unpredictable failure of a nebuliser in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.

    Aerosol generators
    78.
    发明授权
    Aerosol generators 有权
    气溶胶发生器

    公开(公告)号：US09522409B2

    公开(公告)日：2016-12-20

    申请号：US13720759

    申请日：2012-12-19

    Applicant: Stamford Devices Limited

    Inventor： Brendan Hogan ,  Daniela Butan ,  Seamus Clifford ,  Michael Pomeroy ,  Mark Southern ,  David Sheil

    IPC: B05B17/00 ,  B05B17/06

    CPC classification number: B05B17/0646 ,  B05B15/18 ,  B05B17/06 ,  B05B17/0653 ,  B05B17/0669

    Abstract: An aperture plate is formed from a palladium nickel alloy comprising about 89% palladium and about 11% nickel. There is a generally fine substantially equiaxed grain microstructure throughout the thickness of the aperture plate. The average grain width (W) is in the range of from 0.2 μm to 5.0 μm, in some cases from 0.2 μm to 2.0 μm. Because the grain structure is equiaxed (L/W=1) the grain length (L) is the same as the grain width. The improved aperture plate extends the life of nebulizers, eliminates the risk of premature and unpredictable failure of a nebulizer in service, eliminates the risk of product returns from hospitals and patients, and eliminates the possible risk of fragments of the aperture plate breaking free from the nebulizer.

    Abstract translation: 孔板由包含约89％钯和约11％镍的钯镍合金形成。 在孔板的整个厚度上存在通常细的基本上等轴晶粒微观结构。 平均晶粒宽度（W）在0.2μm至5.0μm的范围内，在某些情况下为0.2μm至2.0μm。 由于晶粒结构为等轴（L / W = 1），晶粒长度（L）与晶粒宽度相同。 改进的孔板延长了喷雾器的使用寿命，消除了雾化器在使用中过早和不可预测的故障的风险，消除了医院和患者返回产品的风险，并消除了孔板破碎的可能性。 喷雾器。

    SUPPLEMENTAL OXYGEN DELIVERY SYSTEM
    79.
    发明申请
    SUPPLEMENTAL OXYGEN DELIVERY SYSTEM 有权
    补充氧气输送系统

    公开(公告)号：US20130199529A1

    公开(公告)日：2013-08-08

    申请号：US13829044

    申请日：2013-03-14

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： John Sylvester Power ,  James B. Fink ,  Conor Paul Duffy ,  Trevor Stephen Fahy

    IPC: A61M16/16 ,  A61M16/08 ,  A61M16/06 ,  A61M16/00

    CPC classification number: A61M16/14 ,  A61M11/002 ,  A61M11/003 ,  A61M11/005 ,  A61M15/0085 ,  A61M16/0057 ,  A61M16/0666 ,  A61M16/0672 ,  A61M16/0833 ,  A61M16/0875 ,  A61M16/147 ,  A61M16/16 ,  A61M2202/0208 ,  A61M2206/14 ,  B05B12/081 ,  B05B17/0646 ,  B05B17/0669

    Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

    Abstract translation: 描述了补充氧气输送系统，其中气溶胶被输送到壳体10,20中，壳体10,20从补充氧气供应和可选的加湿器位于电路中。 补充的氧通过其中所述气溶胶所在的腔室10,20，并收集通过鼻插管3或面罩4将其运送到患者的气溶胶。气溶胶发生器9安装到壳体10,20上， 将气溶胶递送到在壳体10的入口14和出口15之间流动的氧气流13.壳体10还具有在其底部17中的可移除的塞子16，用于排出积聚在壳体10中的任何液体。不存在中断 使用鼻塞的患者的氧气输送，当接受雾化药物时，目前必须使用单独的面罩。

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