Crystalline and amorphous forms of beta-L-2′-deoxythymidine
    72.
    发明授权
    Crystalline and amorphous forms of beta-L-2′-deoxythymidine 有权
    β-L-2'-deoxythymidine的结晶和无定形形式

    公开(公告)号:US07858594B2

    公开(公告)日:2010-12-28

    申请号:US12505839

    申请日:2009-07-20

    IPC分类号: A01N43/04 A61K31/70

    摘要: Physical forms of beta-L-2′-deoxythymidine are disclosed that can be characterized by physical appearance, purity levels, Infra-Red and Raman spectroscopy, X-ray powder diffraction patterns, thermal properties, and methods of manufacture. These forms of beta-L-2′-deoxythymidine can be used in the manufacture of other forms of beta-L-2′-deoxythymidine, or in pharmaceutical compositions. Particularly preferred uses are in the treatment of hepatitis B.

    摘要翻译: 公开了可以通过物理外观,纯度水平,红外和拉曼光谱学,X射线粉末衍射图,热性质和制造方法来表征的β-L-2'-脱氧胸苷的物理形式。 这些形式的β-L-2'-脱氧胸苷可用于制造其它形式的β-L-2'-脱氧胸苷,或用于药物组合物中。 特别优选的用途是治疗乙型肝炎。

    Crystalline and amorphous forms of beta-L-2′-deoxythymidine
    75.
    发明授权
    Crystalline and amorphous forms of beta-L-2′-deoxythymidine 有权
    β-L-2'-deoxythymidine的结晶和无定形形式

    公开(公告)号:US07323451B2

    公开(公告)日:2008-01-29

    申请号:US10636349

    申请日:2003-08-06

    摘要: Physical forms of beta-L-2′-deoxythymidine are disclosed that can be characterized by physical appearance, purity levels, Infra-Red and Raman spectroscopy, X-ray powder diffraction patterns, thermal properties, and methods of manufacture. These forms of beta-L-2′-deoxythymidine can be used in the manufacture of other forms of beta-L-2′-deoxythymidine, or in pharmaceutical compositions. Particularly preferred uses are in the treatment of hepatitis B.

    摘要翻译: 公开了可以通过物理外观,纯度水平,红外和拉曼光谱学,X射线粉末衍射图,热性质和制造方法来表征的β-L-2'-脱氧胸苷的物理形式。 这些形式的β-L-2'-脱氧胸苷可用于制造其它形式的β-L-2'-脱氧胸苷,或用于药物组合物中。 特别优选的用途是治疗乙型肝炎。

    Bird vaccinating device and method of operation
    80.
    发明授权
    Bird vaccinating device and method of operation 有权
    鸟疫苗装置及其操作方法

    公开(公告)号:US06609479B2

    公开(公告)日:2003-08-26

    申请号:US10035341

    申请日:2002-01-04

    IPC分类号: A01K3700

    CPC分类号: A01K45/00 A61D1/025

    摘要: The bird vaccinating device comprises a frame, a drum or carosel rotatable on a vertical axis or this frame, schackle means for attaching birds, and being angularly spaced on said drum, motor means to rotate said drum, to present the bird successively to different operating stations, wherein said drum has a polygonal shape, preferably octagonal, each lateral side of the polygon providing a flat surface, said schackle means protruding from said surface so that an attached bird can be backed on to this flat surface by the vaccinator for proper vaccination. Preferably means are provided to cause the drum to stop if grasped by a vaccinator and to release automatically the vaccinated bird, preferably on a slide, as well as to count the vaccinated birds.

    摘要翻译: 禽鸟疫苗装置包括可在垂直轴线或该框架上旋转的框架,滚筒或carosel,用于附接鸟类的钩形装置,并且在所述滚筒上成角度地间隔开,马达装置使所述滚筒旋转,将鸟类连续呈现不同的操作 站,其中所述滚筒具有多边形形状,优选八边形,多边形的每个侧面提供平坦表面,所述分支装置从所述表面突出,使得附接的鸟可以由所述接触器支撑到所述平坦表面上以进行适当的接种 。 优选地,提供用于使鼓停止的装置,如果由接种者抓住并且自动释放接种疫苗的鸟,优选在载玻片上释放,以及计数接种疫苗的鸟。