公开(公告)号：US20070045422A1

公开(公告)日：2007-03-01

申请号：US11511223

申请日：2006-08-29

申请人： Makoto Ito

发明人： Makoto Ito

IPC分类号： G06K7/10

CPC分类号： G06K7/10722

摘要： In an optical information reader, a case, and a light source is installed in the case. The light source supplies light. A lens is installed in the case and focuses the supplied light through part of the case onto optical information attached to a target. A particle blocking member is installed in the case to be arranged between the part of the case and the light source. The particle blocking member allows light reflected from the optical information to pass therethrough. The particle blocking member is integrally provided with a holder configured to support the light source. The particle blocking member blocks flow of particles into the light source side in the case.

摘要翻译： 在光学信息阅读器中，壳体和光源安装在壳体中。 光源提供光源。 镜头安装在外壳中，并将提供的光通过外壳的一部分聚焦到连接到目标的光学信息上。 颗粒阻挡构件安装在壳体中以布置在壳体的一部分和光源之间。 粒子阻挡构件允许从光学信息反射的光通过。 颗粒阻挡构件一体地设置有支撑光源的支架。 在这种情况下，颗粒阻挡构件阻挡颗粒流入光源侧。

公开(公告)号：US20060251296A1

公开(公告)日：2006-11-09

申请号：US11377149

申请日：2006-03-16

申请人： Nobukatsu Nishida ,  Kazuyuki Uragami ,  Makoto Ito ,  Naoto Takeda

发明人： Nobukatsu Nishida ,  Kazuyuki Uragami ,  Makoto Ito ,  Naoto Takeda

IPC分类号： G06K9/00 ,  H04N1/409

CPC分类号： H04N1/6052 ,  B41M1/14 ,  G03F3/101 ,  H04N1/6033

摘要： In a method for improving the color reproducibility of printed matter to be produced by a printing press in proof print produced by a proof press, a look-up table containing converted values of image data over the entire color space with respect to the proof press is created, the look-up table is corrected based on the color of a printing paper for the printing press and a paper exposed area factor in the proofing, and proof print is created by the use of the corrected look-up table. Furthermore, proof printing image data, in which each of levels of monochromatic color gradation of black on the printed matter is represented on the proof print, out of the proof printing image data over the entire color space in a subtractive process resulting from color matching between proof print by the proof press and the printed matter by means of the printing press is corrected in such a manner that a part having a black ink area factor of 100% on the printed matter is represented only with black ink also on the proof print, but that a part other than the part having a black ink area factor of 100% on the printed matter is represented on the proof print by using under color removal, so that the representing characteristics of the black ink on the printed matter are reproduced on the proof print.

公开(公告)号：US07101699B2

公开(公告)日：2006-09-05

申请号：US10381471

申请日：2001-09-26

申请人： Makoto Ito ,  Masako Furusato ,  Noriyuki Sueyoshi

发明人： Makoto Ito ,  Masako Furusato ,  Noriyuki Sueyoshi

IPC分类号： C12N9/80 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

CPC分类号： C07K16/40 ,  A61K38/00 ,  C12N9/80

摘要： A polypeptide possessing a sphingolipid ceramide deacylase activity; a nucleic acid encoding the polypeptide; a recombinant DNA comprising the nucleic acid; a carrier for introducing into a cell, carrying the nucleic acid or the recombinant DNA; a transformant harboring the nucleic acid or the recombinant DNA; an oligonucleotide probe or primer for the nucleic acid; a method for detecting the nucleic acid using the probe or the primer and a kit usable therefor; an antibody or a fragment thereof against the polypeptide; and a method for detecting the polypeptide using the antibody or a fragment thereof and a kit usable therefor. According to the present invention, there can be applied to engineering of sphingolipids, and to treatments for diseases such as diseases of nervous system (for instance, neurodegenerative diseases and the like), leukemia and wounds.

摘要翻译： 具有神经鞘脂神经酰胺脱酰酶活性的多肽; 编码该多肽的核酸; 包含该核酸的重组DNA; 用于引入细胞携带核酸或重组DNA的载体; 携带核酸或重组DNA的转化体; 用于核酸的寡核苷酸探针或引物; 使用探针或引物检测核酸的方法和可用于其的试剂盒; 针对多肽的抗体或其片段; 以及使用抗体或其片段检测多肽的方法和可用于其的试剂盒。 根据本发明，可以应用鞘脂的工程化，神经系统疾病（例如神经变性疾病等），白血病和伤口等疾病的治疗。

公开(公告)号：US06949731B2

公开(公告)日：2005-09-27

申请号：US10783097

申请日：2004-02-23

申请人： Makoto Ito

发明人： Makoto Ito

IPC分类号： H01L31/02 ,  H01J40/14 ,  H01L29/74 ,  H01L31/111

CPC分类号： H03F3/087 ,  H01L31/0203 ,  H01L2224/05554 ,  H01L2224/48137 ,  H01L2224/48465

摘要： The present invention provides a light-receiving module that realized a reliable wire bonding from a light-receiving device to a die-capacitor on which the light-receiving device is mounted with adhesive. The light-receiving module of the present invention includes a stem and a die-capacitor disposed on the set. The upper electrode of the die-capacitor has a mounting area where the light-receiving device is mounted, a bonding area to which the bonding-wire is to be bonded, and a structure for interrupting the adhesive from spreading from the mounting area to the bonding area. Since the adhesive for die-bonding the light-receiving device in the mounting area does not spread to the bonding area, the wire-bonding to the bonding area can be reliably performed.

摘要翻译： 本发明提供了一种光接收模块，其实现了从光接收装置到其上安装有光接收装置的模具电容器的可靠的引线接合。 本发明的光接收模块包括设置在组件上的杆和模具电容器。 模具电容器的上部电极具有安装光接收装置的安装区域，接合线将被接合的接合区域，以及用于阻止粘合剂从安装区域延伸到 粘合区域。 由于在安装区域中用于芯片接合光接收装置的粘合剂不会扩散到接合区域，因此可以可靠地进行与接合区域的接合。

公开(公告)号：US06900512B2

公开(公告)日：2005-05-31

申请号：US10373186

申请日：2003-02-26

申请人： Kenichiro Kohmoto ,  Takeshi Sekiguchi ,  Motoyoshi Tanaka ,  Makoto Ito

发明人： Kenichiro Kohmoto ,  Takeshi Sekiguchi ,  Motoyoshi Tanaka ,  Makoto Ito

IPC分类号： H01L31/02 ,  H01L27/14 ,  H01L29/06 ,  H01L31/00 ,  H01L31/0203 ,  H01L31/0232

CPC分类号： H01L25/167 ,  H01L31/0203 ,  H01L2224/05554 ,  H01L2224/48137 ,  H01L2224/49171 ,  H01L2924/3011 ,  H01L2924/30111 ,  H01L2924/00

摘要： This invention relates to a light-receiving module in which transmission impedance of lead terminals are matched by simple method. The module has a semiconductor light-receiving device, such as a photo diode, a plurality of lead terminals for transmitting an electrical signal converted by the semiconductor device, and a metal base with a plurality of through holes, the lead terminals passes therethrough. The diameter of the lead terminal for signal transmission is smaller as compared with that of other lead terminal and the diameter of the through holes is adjusted and filled by a sealant glass with a dielectric constant so as to match the impedance thereof.

摘要翻译： 本发明涉及通过简单的方法匹配引线端子的传输阻抗的光接收模块。 该模块具有诸如光电二极管的半导体光接收装置，用于传输由半导体器件转换的电信号的多个引线端子和具有多个通孔的金属基座，引线端子穿过其中。 用于信号传输的引线端子的直径与其它引线端子的直径相比较小，并且通孔的直径由具有介电常数的密封剂玻璃调节和填充以匹配其阻抗。

公开(公告)号：US06823288B2

公开(公告)日：2004-11-23

申请号：US10655003

申请日：2003-09-05

申请人： Makoto Ito ,  Tadashi Takai ,  Tomotsune Taira ,  Masanori Takagi ,  Yukio Ito

发明人： Makoto Ito ,  Tadashi Takai ,  Tomotsune Taira ,  Masanori Takagi ,  Yukio Ito

IPC分类号： G06F1130

CPC分类号： F24F11/30 ,  F24F11/57 ,  F24F11/58

摘要： A service system which includes the monitoring center which has a customer database, an operation information database for storing operation information of the air conditioners for each customer, and a device information database 203 having device information on the air conditioners related with each customer of the customer database. When the system decides that there is anomaly in the operation information, the monitoring center sends to the cellular phone over the Internet information representing the content of the anomaly and customer and device information associated with the operation information which was judged abnormal.

摘要翻译： 一种服务系统，包括具有客户数据库的监控中心，用于存储每个客户的空调的操作信息的操作信息数据库，以及具有与客户的每个客户相关的空调的设备信息的设备信息数据库203 数据库。 当系统确定操作信息有异常时，监控中心通过因特网向移动电话发送表示异常内容的信息和与被判定为异常的操作信息相关的客户和设备信息。

公开(公告)号：US06806547B2

公开(公告)日：2004-10-19

申请号：US10397839

申请日：2003-03-27

申请人： Kenichiro Kohmoto ,  Takeshi Sekiguchi ,  Makoto Ito

发明人： Kenichiro Kohmoto ,  Takeshi Sekiguchi ,  Makoto Ito

IPC分类号： H01L310203

CPC分类号： H01L31/0203 ,  G02B6/4263 ,  G02B6/4279 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48137 ,  H01L2224/48465 ,  H01L2924/30107 ,  H01L2924/3011 ,  H01L2924/00

摘要： An optical module comprises a photodiode, an amplifying device, and a die capacitor. The die capacitor has at least a center pad, the photodiode is mounted thereon, and other pads on both side of the center pad. The die capacitor is mounted on a mounting surface of the module so as to locate the photodiode to be center of the surface. The amplifying device has a signal pad and a plural ground pad surrounding the signal pad. The signal pad is connected to the photodiode, while the ground pads are connected to the mounting surface through other pads on both side of the die capacitor.

摘要翻译： 光学模块包括光电二极管，放大器件和管芯电容器。 管芯电容器至少具有中心焊盘，光电二极管安装在其上，以及位于中心焊盘两侧的其它焊盘。 模具电容器安装在模块的安装表面上，以将光电二极管定位在表面的中心。 放大装置具有信号焊盘和围绕信号焊盘的多个接地焊盘。 信号焊盘连接到光电二极管，而接地焊盘通过芯片电容器两侧的其他焊盘连接到安装表面。

公开(公告)号：US06492199B2

公开(公告)日：2002-12-10

申请号：US09773653

申请日：2001-01-31

申请人： Kenji Osawa ,  Kazuhiro Sato ,  Makoto Ito

发明人： Kenji Osawa ,  Kazuhiro Sato ,  Makoto Ito

IPC分类号： H01L2148

CPC分类号： H01L23/24 ,  H01L23/495 ,  H01L24/45 ,  H01L24/48 ,  H01L2224/45144 ,  H01L2224/48091 ,  H01L2224/48472 ,  H01L2924/00014 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/07802 ,  H01L2924/15311 ,  H01L2924/181 ,  H01L2924/3025 ,  H01L2924/00 ,  H01L2924/00015 ,  H01L2224/05599 ,  H01L2924/00012

摘要： A method of manufacturing a semiconductor chip that has electrode pads on the chip front surface and disposed inside a conductive outer ring. A film circuit is disposed on the chip front surface side. External connection thermals are formed on the film circuit so as to project there from. First leads electrically connect part of the electrode pads to part of the external connection terminals. A second lead electrically connects a grounding or power supply electrode pad to the outer ring, and a third lead electrically connects a grounding or power supply external connection terminal to the outer ring.

摘要翻译： 一种制造半导体芯片的方法，该半导体芯片在芯片前表面上具有设置在导电外圈内部的电极焊盘。 薄片电路设置在芯片正面侧。 在薄膜电路上形成外部连接热量，从而在其上突出。 第一引线将电极焊盘的一部分电连接到外部连接端子的一部分。 第二引线将接地或电源电极焊盘电连接到外环，而第三引线将接地或电源外部连接端子电连接到外环。

公开(公告)号：US06489117B2

公开(公告)日：2002-12-03

申请号：US09777710

申请日：2001-02-07

申请人： Nozomu Okino ,  Makoto Ito

发明人： Nozomu Okino ,  Makoto Ito

IPC分类号： C12G168

CPC分类号： C12N9/80

摘要： To provide a polypeptide having ceramidase activity, and a gene encoding thereof useful as an reagent for lipid engineering and as indices for diagnosis of atopic dermatitis, an easy method for detecting the polypeptide and method for detecting the gene as well as a method for detecting atopic dermatitis. A polypeptide having an amino acid sequence as shown in SEQ ID NO: 1 in Sequence Listing, or a polypeptide having an amino acid sequence which has substitution, deletion, addition or insertion of one or more amino acids in the amino acid sequence of SEQ ID NO: 1 and having ceramidase activity; a gene encoding the polypeptide; a gene capable of hybridizing with the above genes under stringent conditions, and encoding a polypeptide having ceramidase activity; an oligonucleotide probe or primer, which is capable of hybridizing under stringent conditions with the above genes or with a gene having a nucleotide sequence complementary thereto; a method for detecting a gene encoding a polypeptide having ceramidase activity, by using the oligonucleotide probe and/or primer; an antibody or a fragment thereof, which is capable of specifically binding to the polypeptide; a method for detecting a polypeptide having ceramidase activity, by using the above antibody or fragment thereof; a method for detecting atopic dermatitis, by the methods.

摘要翻译： 为了提供具有神经酰胺酶活性的多肽，以及编码其可用作脂质工程试剂的基因和用于诊断特应性皮炎的指标，用于检测多肽的简便方法和用于检测该基因的方法以及用于检测特应性的方法 皮炎。 具有序列表中SEQ ID NO：1所示的氨基酸序列的多肽或具有氨基酸序列的氨基酸序列的氨基酸序列中具有氨基酸序列的氨基酸序列的取代，缺失，添加或插入的多肽 NO：1并具有神经酰胺酶活性; 编码该多肽的基因; 能够在严格条件下与上述基因杂交的基因，并编码具有神经酰胺酶活性的多肽; 寡核苷酸探针或引物，其能够在严格条件下与上述基因或与其核苷酸序列互补的基因杂交; 通过使用寡核苷酸探针和/或引物检测编码具有神经酰胺酶活性的多肽的基因的方法; 能够特异性结合多肽的抗体或其片段; 通过使用上述抗体或其片段检测具有神经酰胺酶活性的多肽的方法; 一种通过该方法检测特应性皮炎的方法。

公开(公告)号：US06258581B1

公开(公告)日：2001-07-10

申请号：US09328501

申请日：1999-06-09

申请人： Nozomu Okino ,  Makoto Ito

发明人： Nozomu Okino ,  Makoto Ito

IPC分类号： C12N914

CPC分类号： C12N9/80

摘要： To provide a polypeptide having ceramidase activity, and a gene encoding thereof useful as an reagent for lipid engineering and as indices for diagnosis of atopic dermatitis, an easy method for detecting the polypeptide and method for detecting the gene as well as a method for detecting atopic dermatitis. A polypeptide having an amino acid sequence as shown in SEQ ID NO: 1 in Sequence Listing, or a polypeptide having an amino acid sequence which has substitution, deletion, addition or insertion of one or more amino acids in the amino acid sequence of SEQ ID NO: 1 and having ceramidase activity; a gene encoding the polypeptide; a gene capable of hybridizing with the above genes under stringent conditions, and encoding a polypeptide having ceramidase activity; an oligonucleotide probe or primer, which is capable of hybridizing under stringent conditions with the above genes or with a gene having a nucleotide sequence complementary thereto; a method for detecting a gene encoding a polypeptide having ceramidase activity, by using the oligonucleotide probe and/or primer; an antibody or a fragment thereof, which is capable of specifically binding to the polypeptide; a method for detecting a polypeptide having ceramidase activity, by using the above antibody or fragment thereof; a method for detecting atopic dermatitis, by the methods.

摘要翻译： 为了提供具有神经酰胺酶活性的多肽，以及编码其可用作脂质工程试剂的基因和用于诊断特应性皮炎的指标，用于检测多肽的简便方法和用于检测该基因的方法以及用于检测特应性的方法 皮炎。 具有序列表中SEQ ID NO：1所示的氨基酸序列的多肽或具有氨基酸序列的氨基酸序列的氨基酸序列中具有氨基酸序列的氨基酸序列的取代，缺失，添加或插入的多肽 NO：1并具有神经酰胺酶活性; 编码该多肽的基因; 能够在严格条件下与上述基因杂交的基因，并编码具有神经酰胺酶活性的多肽; 寡核苷酸探针或引物，其能够在严格条件下与上述基因或与其核苷酸序列互补的基因杂交; 通过使用寡核苷酸探针和/或引物检测编码具有神经酰胺酶活性的多肽的基因的方法; 能够特异性结合多肽的抗体或其片段; 通过使用上述抗体或其片段检测具有神经酰胺酶活性的多肽的方法; 一种通过该方法检测特应性皮炎的方法。