公开(公告)号：US20050181536A1

公开(公告)日：2005-08-18

申请号：US11042809

申请日：2005-01-25

申请人： Takashi Tsuji

发明人： Takashi Tsuji

IPC分类号： H01L21/00 ,  H01L21/04 ,  H01L29/04 ,  H01L29/15 ,  H01L29/24 ,  H01L29/267 ,  H01L29/78 ,  H01L31/0312

CPC分类号： H01L29/7802 ,  H01L21/0445 ,  H01L21/046 ,  H01L21/047 ,  H01L29/045 ,  H01L29/1608 ,  H01L29/267 ,  H01L29/66068 ,  H01L29/7813 ,  H01L29/7842 ,  Y10S438/931

摘要： Stress is exerted to the SiC crystal in the region, in which the carriers of a SiC semiconductor device flow, to change the crystal lattice intervals of the SiC crystal. Since the degeneration of the conduction bands in the bottoms thereof is dissolved, since the inter-band scattering is prevented from causing, and since the effective electron mass is reduced due to the crystal lattice interval change, the carrier mobility in the SiC crystal is improved, the resistance of the SiC crystal is reduced and, therefore, the on-resistance of the SiC semiconductor device is reduced.

摘要翻译： 在SiC半导体器件的载流子流动的区域中，对SiC晶体施加应力，以改变SiC晶体的晶格间隔。 由于其底部导带的退化被溶解，因此防止带间散射引起，并且由于晶格间隔变化引起的有效电子质量降低，所以提高了SiC晶体的载流子迁移率 ，SiC晶体的电阻降低，因此SiC半导体器件的导通电阻降低。

公开(公告)号：US06803039B2

公开(公告)日：2004-10-12

申请号：US09859053

申请日：2001-05-16

申请人： Takashi Tsuji ,  Katsunari Tezuka ,  Nobuaki Hori

发明人： Takashi Tsuji ,  Katsunari Tezuka ,  Nobuaki Hori

IPC分类号： A61K39395

CPC分类号： C07K16/18 ,  A01K2217/05 ,  A61K2039/505 ,  C07K16/28 ,  C07K16/2818 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/00 ,  C07K2319/30

摘要： Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that the human monoclonal antibody is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases.

摘要翻译： 用AILIM分子作为抗原，使用基因工程技术产生的产生抗体的转基因小鼠的免疫导致能够结合AILIM并能够控制多种生物反应的各种人单克隆抗体（例如，细胞增殖 ，细胞因子产生，免疫细胞溶解，细胞死亡，诱导ADCC等）与AILIM介导的共刺激信号（二级信号）转导相关。 此外，已经揭示了人单克隆抗体有效治疗和预防与AILIM介导的共刺激信号转导相关的各种疾病，能够抑制疾病的发病和/或进展。

公开(公告)号：US06562808B1

公开(公告)日：2003-05-13

申请号：US09522946

申请日：2000-03-10

申请人： Katsutoshi Sakata ,  Takashi Tsuji ,  Noriko Sasaki ,  Kazuyoshi Takahashi

发明人： Katsutoshi Sakata ,  Takashi Tsuji ,  Noriko Sasaki ,  Kazuyoshi Takahashi

IPC分类号： A61K31553

CPC分类号： C07D413/06

摘要： 5,11-dihydrodibenzo[b,e][1,4]oxazepine derivatives of the following general formulae and analogs thereof have a calcium channel-antagonistic effect and they are effective in treating and preventing intestinal diseases such as abnormal motor function of digestive tracts, particularly, irritable bowel syndrome:

摘要翻译： 具有以下通式的5,11-二氢二苯并[b，e] [1,4]氧氮杂衍生物及其类似物具有钙通道拮抗作用，它们有效治疗和预防肠道疾病如消化道运动功能异常 ，特别是肠易激综合征：

公开(公告)号：US4548550A

公开(公告)日：1985-10-22

申请号：US609084

申请日：1984-05-11

申请人： Takashi Tsuji

发明人： Takashi Tsuji

IPC分类号： A61M1/10 ,  F04B43/06

CPC分类号： A61M1/1086 ,  A61M1/1037

摘要： A method and system for pneumatically driving a pump for an artificial heart is disclosed which can pump blood as approximate as possible to the natural heart without increasing the capacity of any pressure tank. A compensation drive pressure which compensates for the drop of the drive pressure is additionally applied to the pump whenever the drive pressure is applied to the pump.

摘要翻译： 公开了一种气动驱动用于人造心脏的泵的方法和系统，其可以在不增加任何压力罐的容量的情况下将血液尽可能近似地泵送到天然心脏。 当驱动压力施加到泵时，补偿驱动压力下降的补偿驱动压力另外施加到泵。

公开(公告)号：US09982238B2

公开(公告)日：2018-05-29

申请号：US13983701

申请日：2011-07-07

申请人： Koh-ei Toyoshima ,  Takashi Tsuji

发明人： Koh-ei Toyoshima ,  Takashi Tsuji

IPC分类号： A61K35/12 ,  C12N5/071 ,  A61L27/38

CPC分类号： C12N5/0697 ,  A61K35/12 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/3886 ,  A61L2430/18 ,  C12N5/0627 ,  C12N5/0633 ,  C12N2502/13 ,  C12N2502/1376 ,  C12N2533/54

摘要： A method for producing a regenerative organ germ for transplantation includes using regenerative organ germ for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. A method for producing a regenerative organ germ provided with a guide for transplantation includes preparing a regenerative organ germ by closely contacting a first cell mass, which substantially consists of mesenchymal cells, and a second cell mass, which substantially consists of epithelial cells, culturing these cell masses within a support, and inserting the guide into the regenerative organ germ.

公开(公告)号：US09564116B2

公开(公告)日：2017-02-07

申请号：US13992671

申请日：2011-12-09

申请人： Takashi Tsuji ,  Naoya Azuma ,  Yasushi Nagano

发明人： Takashi Tsuji ,  Naoya Azuma ,  Yasushi Nagano

IPC分类号： G01K11/04 ,  G10K11/00 ,  B60R19/48 ,  G01S7/521 ,  G01S15/93

CPC分类号： G10K11/004 ,  B60R19/483 ,  G01S7/521 ,  G01S2015/937 ,  G01S2015/938

摘要： The ultrasonic-transducer mounting structure includes: a housing including: a body part which is formed into a hollow cylindrical shape and is provided at its front surface with a transmission surface allowing an ultrasonic wave to pass therethrough and is designed to accommodate an ultrasonic transducer therein; and plural connection pieces provided to a side surface of the body part; and a holder fixed to a rear surface of a bumper and designed to hold the housing such that the transmission surface of the housing is exposed via an opening of the bumper. The holder includes plural reception pieces to which the plural connection pieces are detachably coupled respectively. The plural reception pieces are fixed to the rear surface of the bumper to surround the opening.

摘要翻译： 超声换能器安装结构包括：壳体，包括：主体部分，其形成为中空圆柱形，并在其前表面设置有允许超声波通过的传输表面，并被设计成在其中容纳超声换能器 ; 以及设置在所述主体部的侧面的多个连接片; 以及保持器，其固定到保险杠的后表面并且被设计成保持壳体，使得壳体的传动表面经由保险杠的开口暴露。 保持器包括多个接合件，多个连接件分别可拆卸地连接到该接收件。 多个接收件被固定到保险杠的后表面以包围开口。

公开(公告)号：US09321998B2

公开(公告)日：2016-04-26

申请号：US14000939

申请日：2012-02-21

申请人： Koh-ei Toyoshima ,  Takashi Tsuji

发明人： Koh-ei Toyoshima ,  Takashi Tsuji

IPC分类号： C12N5/071 ,  C12N5/074 ,  A61L27/38

CPC分类号： C12N5/0697 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/3886 ,  A61L27/3891 ,  A61L2430/18 ,  C12N2506/092 ,  C12N2506/1376

摘要： A method for producing a regenerative hair follicle germ for transplantation, in which a color of hair that grows after transplantation is controlled, includes preparing a first cell mass containing mesenchymal cells; preparing a second cell mass containing epithelial cells; preparing a cell mass containing pigment stem cells; binding the cell mass containing the pigment stem cells to at least one among the first cell mass and the second cell mass, and closely contacting the first cell mass and the second cell mass, at least one of which has been bound to the cell mass containing the pigment stem cells, and culturing them within a support.

摘要翻译： 一种生产用于移植的再生毛囊胚芽的方法，其中控制移植后生长的毛发的颜色，包括制备含有间充质细胞的第一细胞块; 制备含有上皮细胞的第二细胞团; 制备含有色素干细胞的细胞团; 将含有色素干细胞的细胞团结合到第一细胞团和第二细胞团中的至少一个，并且紧密接触第一细胞团和第二细胞团，其中至少一个细胞团与第二细胞团结合， 色素干细胞，并在支持体内培养它们。

公开(公告)号：US08679755B2

公开(公告)日：2014-03-25

申请号：US13718749

申请日：2012-12-18

申请人： Takashi Tsuji ,  Kazuhisa Nakao

发明人： Takashi Tsuji ,  Kazuhisa Nakao

IPC分类号： C12Q1/68 ,  C12N11/18 ,  C12N5/00

CPC分类号： C12N5/0062 ,  A61K35/12 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/3865 ,  A61L27/3886 ,  A61L2430/12 ,  C12N5/0627 ,  C12N5/0654 ,  C12N2502/097 ,  C12N2533/54

摘要： A first cell mass substantially containing only either one of mesenchymal cells or epithelial cells and a second cell mass substantially containing only the other one of the cells are positioned in contact with each other inside a support carrier which can maintain a condition of cell contact; and cultured to obtain a tooth having a specific cell placement. Preferably, after the culturing, the support carrier having both cell masses is cultured with kidney cells.

摘要翻译： 基本上仅含有间充质细胞或上皮细胞中的任一种的第一细胞团和基本上仅含有另一个细胞的第二细胞团彼此定位在可保持细胞接触状态的载体载体内彼此接触; 并培养以获得具有特定细胞放置的牙齿。 优选培养后，将具有两个细胞块的载体载体与肾细胞一起培养。

公开(公告)号：US20140037592A1

公开(公告)日：2014-02-06

申请号：US13983701

申请日：2011-07-07

申请人： Koh-ei Toyoshima ,  Takashi Tsuji

发明人： Koh-ei Toyoshima ,  Takashi Tsuji

IPC分类号： C12N5/071

CPC分类号： C12N5/0697 ,  A61K35/12 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/3886 ,  A61L2430/18 ,  C12N5/0627 ,  C12N5/0633 ,  C12N2502/13 ,  C12N2502/1376 ,  C12N2533/54

摘要： A method for producing a regenerative organ germ for transplantation includes using regenerative organ germ for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. A method for producing a regenerative organ germ provided with a guide for transplantation includes preparing a regenerative organ germ by closely contacting a first cell mass, which substantially consists of mesenchymal cells, and a second cell mass, which substantially consists of epithelial cells, culturing these cell masses within a support, and inserting the guide into the regenerative organ germ.

摘要翻译： 一种用于移植的再生器官胚芽的制备方法包括使用再生器官细菌进行移植，确保移植后接受者的连续性，并促进移植手术。 制备具有移植指南的再生器官细菌的方法包括通过紧密接触基本上由间充质细胞组成的第一细胞块和基本上由上皮细胞组成的第二细胞块来制备再生器官细菌，培养它们 支撑体内的细胞块，将引导件插入再生器官细菌。

公开(公告)号：US20130101951A1

公开(公告)日：2013-04-25

申请号：US13638962

申请日：2011-03-15

申请人： Takashi Tsuji ,  Kazuhisa Nakao ,  Masamitsu Oshima

发明人： Takashi Tsuji ,  Kazuhisa Nakao ,  Masamitsu Oshima

IPC分类号： A61D5/00

CPC分类号： A61D5/00 ,  A61C13/08 ,  A61L27/24 ,  A61L27/38 ,  A61L27/3813 ,  A61L27/3834 ,  A61L27/3886 ,  A61L2430/12

摘要： The object of the present invention is to provide a method for restoring the alveolar bone of a mammal with a missing tooth.The present invention provides a method for restoring the alveolar bone in a mammal with a missing tooth comprising a step of transplanting a regenerated tooth unit to the said missing site. The regenerated tooth unit is characterized in that it has a periodontal tissue portion in addition to a tooth crown portion.

摘要翻译： 本发明的目的是提供一种用于恢复具有缺牙的哺乳动物的牙槽骨的方法。 本发明提供了一种用于恢复具有缺牙的哺乳动物中的牙槽骨的方法，包括将再生牙齿单元移植到所述缺失部位的步骤。 再生齿单元的特征在于除了牙冠部分之外还具有牙周组织部分。