USE OF A COMBINATION OF MYXOMA VIRUS AND RAPAMYCIN FOR THERAPEUTIC TREATMENT
    75.
    发明申请
    USE OF A COMBINATION OF MYXOMA VIRUS AND RAPAMYCIN FOR THERAPEUTIC TREATMENT 审中-公开
    使用MYXOMA病毒和RAPAMYCIN进行治疗治疗的组合

    公开(公告)号:US20110195050A1

    公开(公告)日:2011-08-11

    申请号:US12850599

    申请日:2010-08-04

    摘要: The present invention relates to therapeutic use of a combination of Myxoma virus, including in combination with rapamycin. Treatment with rapamycin enhances the ability of Myxoma virus to selectively infect cells that have a deficient innate anti-viral response, including cells that are not responsive to interferon. The combination of rapamycin and Myxoma virus can be used to treat diseases characterized by the presence of such cells, including cancer. The invention also relates to therapeutic use of Myxoma virus that does not express functional M135R.

    摘要翻译: 本发明涉及粘液瘤病毒的组合的治疗用途,包括与雷帕霉素组合。 用雷帕霉素治疗增强粘液瘤病毒选择性感染具有缺陷先天性抗病毒应答的细胞的能力,包括对干扰素无反应的细胞。 雷帕霉素和粘液瘤病毒的组合可用于治疗特征在于存在这种细胞(包括癌症)的疾病。 本发明还涉及不表达功能性M135R的粘液瘤病毒的治疗用途。

    Universal exercise system
    76.
    发明授权
    Universal exercise system 失效
    普遍运动系统

    公开(公告)号:US5827156A

    公开(公告)日:1998-10-27

    申请号:US589919

    申请日:1996-01-23

    申请人: John Barrett

    发明人: John Barrett

    IPC分类号: A63B21/072 A63B21/075

    摘要: This invention relates to methods, devices and systems for exercise. An embodiment of this invention comprises a circular exercise wheel in the shape of a conventional automobile steering wheel with a weight attached along its diameter with a pair of wing nuts. The wing-nuts and bolts are attached such that they cannot be lost or stolen or misplaced.

    摘要翻译: 本发明涉及用于运动的方法,装置和系统。 本发明的一个实施例包括一种常规汽车方向盘形状的圆形运动轮,其重量沿其直径与一对翼形螺母相连。 翼螺母和螺栓的连接不会丢失或被盗或放错。