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188 条记录 (耗时 0.073 秒)

    Antibodies against vascular endothelial growth factor receptor-1
    74.
    发明授权
    Antibodies against vascular endothelial growth factor receptor-1 有权
    抗血管内皮生长因子受体-1的抗体

    公开(公告)号：US07972596B2

    公开(公告)日：2011-07-05

    申请号：US11719677

    申请日：2005-11-18

    申请人： Yan Wu ,  Danny J. Hicklin ,  Peter Bohlen

    发明人： Yan Wu ,  Danny J. Hicklin ,  Peter Bohlen

    IPC分类号： A61K39/395 ,  C12P21/08 ,  C07K16/18 ,  C07K16/28

    CPC分类号： C07K16/2863 ,  A61K39/39541 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  A61K2300/00

    摘要： Monoclonal antibodies that are specific for vascular endothelial growth factor receptor 1 (VEGFR-I). This invention also provides nucleotide sequences encoding and amino acid sequences comprising variable heavy and light chain immunoglobulin molecules, including sequences corresponding to the complementarity determining regions of CDR1, CDR2, and CDR3. The invention also provides methods for generation and expression of anti -VEGFR-I antibodies and methods of treating angiogenic-related disorders and reducing tumor growth by administering anti-VEGFR-I antibodies.

    摘要翻译： 对血管内皮生长因子受体1（VEGFR-1）特异的单克隆抗体。 本发明还提供编码核苷酸序列和包含可变重链和轻链免疫球蛋白分子的氨基酸序列，其包括对应于CDR1，CDR2和CDR3的互补决定区的序列。 本发明还提供了产生和表达抗-VEGFR-1抗体的方法以及通过施用抗VEGFR-1抗体治疗血管生成相关病症并降低肿瘤生长的方法。

    Back channel communication
    76.
    发明授权
    Back channel communication 有权
    后通道通信

    公开(公告)号：US07925935B2

    公开(公告)日：2011-04-12

    申请号：US12100355

    申请日：2008-04-09

    申请人： Massimo Sorbara ,  Patrick Duvaut ,  Yan Wu

    发明人： Massimo Sorbara ,  Patrick Duvaut ,  Yan Wu

    IPC分类号： G06F11/00 ,  G01R31/28 ,  H04B1/38 ,  H04B3/46

    CPC分类号： H04L12/66 ,  H04B3/32

    摘要： Included are embodiments for back channel communication. At least one embodiment of a method includes receiving data at customer premises equipment and determining at least one error in the received data. Some embodiments include formatting the determined error for communication to a central office and sending the formatted error to the central office via a back channel.

    摘要翻译： 包括用于反向信道通信的实施例。 方法的至少一个实施例包括在客户驻地设备处接收数据并确定接收到的数据中的至少一个错误。 一些实施例包括将所确定的错误格式化为中央局的通信，并通过后向信道将格式化的错误发送到中心局。

    Systems and methods for improved bit loading for discrete multi-tone modulated multiple latency applications
    77.
    发明授权
    Systems and methods for improved bit loading for discrete multi-tone modulated multiple latency applications 有权
    用于离散多色调多个延迟应用的改进位加载的系统和方法

    公开(公告)号：US07813434B2

    公开(公告)日：2010-10-12

    申请号：US11559772

    申请日：2006-11-14

    申请人： Yan Wu ,  Lujing Cai ,  William Scholtz ,  Ehud Langberg

    发明人： Yan Wu ,  Lujing Cai ,  William Scholtz ,  Ehud Langberg

    IPC分类号： H04K1/10 ,  H04L27/28

    CPC分类号： H04L27/2608 ,  H04L1/0006 ,  H04L1/0009 ,  H04L1/0057 ,  H04L1/0058 ,  H04L1/006 ,  H04L1/007 ,  H04L5/14

    摘要： Systems and methods for performing bit loading in a dual latency data transmission system. In a computer network, such as an XDSL-based network, carrier channels are allocated between two latency paths. Error sensitive information is transmitted over a latency path employing one or more forward error correction techniques. Latency sensitive information that is relatively more tolerant of errors is transmitted over the other latency path. Rather than employing the lowest coding gain for carrier channels having the two different latency paths, the highest coding gain for each path is used by applying different target S-N-R margins for carrier channels having different latency paths.

    摘要翻译： 用于在双延迟数据传输系统中执行比特加载的系统和方法。 在诸如基于XDSL的网络的计算机网络中，在两个等待时间路径之间分配载波信道。 误差敏感信息通过采用一个或多个前向纠错技术的等待时间路径传输。 通过另一个等待时间路径发送相对更容忍错误的延迟敏感信息。 不是对具有两个不同等待时间路径的载波信道采用最低的编码增益，而是通过对具有不同等待时间路径的载波信道应用不同的目标S-N-R边缘来使用每个路径的最高编码增益。

    Exchange biased pole for reducing the likelihood of domain lockup in perpendicular recording
    78.
    发明授权
    Exchange biased pole for reducing the likelihood of domain lockup in perpendicular recording 有权
    交换偏置极点，以减少垂直记录中域锁定的可能性

    公开(公告)号：US07692895B1

    公开(公告)日：2010-04-06

    申请号：US11401208

    申请日：2006-04-10

    申请人： Yan Wu ,  Gang Herbert Lin

    发明人： Yan Wu ,  Gang Herbert Lin

    IPC分类号： G11B5/147

    CPC分类号： G11B5/3146 ,  G11B5/1278 ,  G11B5/3116

    摘要： A magnetic head for perpendicular recording includes a main pole having a first end and a second end. Coils are positioned with respect to the main pole. A return pole forms first and second return paths for magnetic flux extending from the second end of the main pole. The main pole includes an anti-ferromagnetic layer to pin a remnant magnetic moment in the horizontal direction.

    摘要翻译： 用于垂直记录的磁头包括具有第一端和第二端的主极。 线圈相对于主极定位。 返回杆形成从主极的第二端延伸的磁通的第一和第二返回路径。 主极包括反铁磁层，以在水平方向上引导残余磁矩。