公开(公告)号：US20110267610A1

公开(公告)日：2011-11-03

申请号：US12772063

申请日：2010-04-30

申请人： Min HU ,  Wei Wu ,  Fung Suong Ou ,  Zhen Peng ,  Zhiyong Li ,  R. Stanley Williams

发明人： Min HU ,  Wei Wu ,  Fung Suong Ou ,  Zhen Peng ,  Zhiyong Li ,  R. Stanley Williams

IPC分类号： G01J3/44

CPC分类号： G01N21/658 ,  G01N21/7746

摘要： A compact sensor system comprising: an analysis cell configured for photon-matter interaction, where photons are received from a light source; and an integrated-optical spectral analyzer configured for identifying a set of frequencies, the integrated-optical spectral analyzer comprising: a waveguide coupled with the analysis cell, the waveguide configured for propagating a set of frequencies through the waveguide; one or more ring resonators coupled with the waveguide, the one or more ring resonators comprising a predetermined bandwidth and configured for capturing the set of frequencies corresponding to frequencies within the predetermined bandwidth; and one or more frequency detectors coupled with the one or more tunable ring resonators, the one or more frequency detectors configured for generating electrical signals that identify each of the set of frequencies.

摘要翻译： 一种紧凑的传感器系统，包括：配置用于光子 - 物质相互作用的分析单元，其中从光源接收光子; 所述集成光谱分析仪包括：与所述分析单元耦合的波导，所述波导被配置为通过所述波导传播一组频率;以及波导，其被配置为用于识别一组频率。 一个或多个与所述波导耦合的环形谐振器，所述一个或多个环形谐振器包括预定带宽并被配置用于捕获与所述预定带宽内的频率相对应的频率集合; 以及与所述一个或多个可调环形谐振器耦合的一个或多个频率检测器，所述一个或多个频率检测器被配置用于产生标识所述一组频率中的每一个的电信号。

公开(公告)号：US20110228266A1

公开(公告)日：2011-09-22

申请号：US13129571

申请日：2008-11-17

申请人： Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

发明人： Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44 ,  B05D5/06 ,  B05D3/10 ,  B05D3/00 ,  C23C16/44 ,  B82Y40/00 ,  B82Y20/00

CPC分类号： B82Y20/00 ,  G01N21/658

摘要： A substrate for Surface Enhanced Raman Scattering (SERS). The substrate comprises at least one nanostructure protruding from a surface of the substrate and a SERS active metal over the at least one nanostructure, wherein the SERS active metal substantially covers the at least one nanostructure and the SERS active metal creates a textured layer on the at least one nanostructure.

摘要翻译： 用于表面增强拉曼散射（SERS）的衬底。 衬底包括从衬底的表面突出的至少一个纳米结构和在至少一个纳米结构上的SERS活性金属，其中SERS活性金属基本上覆盖至少一个纳米结构，并且SERS活性金属在其上形成纹理化层 至少一个纳米结构。

公开(公告)号：US20110188035A1

公开(公告)日：2011-08-04

申请号：US12697156

申请日：2010-01-29

申请人： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

发明人： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

IPC分类号： G01J3/44

CPC分类号： G01J3/44

摘要： A vibrating tip surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a nano-needle configured to vibrate. The apparatus includes the nano-needle with a substantially sharp tip at a free end opposite an end attached to a substrate. The tip is configured to adsorb an analyte. The apparatus further includes a vibration source configured to provide an alternating current (AC) electric field that induces a vibration of the free end and the tip of the nano-needle. Vibration of the nano-needle under the influence of the AC electric field facilitates detection of a Raman scattering signal from the analyte adsorbed on the nano-needle tip. The system further includes a synchronous detector configured to be gated cooperatively with the vibration of the nano-needle. The method includes inducing the vibration, illuminating the vibrating tip to produce a Raman signal, and detecting the Raman signal using the detector.

摘要翻译： 振动尖端表面增强拉曼光谱（SERS）装置，系统和方法采用配置为振动的纳米针。 该装置包括在与连接到基底的端相对的自由端处具有基本尖锐的尖端的纳米针。 尖端构造成吸附分析物。 该装置还包括一个被配置为提供交流（AC）电场的振动源，其引起自由端和纳米针的尖端的振动。 在AC电场的影响下，纳米针的振动有助于检测吸附在纳米针尖上的分析物的拉曼散射信号。 该系统还包括配置为与纳米针的振动协同地选通的同步检测器。 该方法包括引起振动，照亮振动尖端以产生拉曼信号，并使用检测器检测拉曼信号。

公开(公告)号：US20110176353A1

公开(公告)日：2011-07-21

申请号：US13120904

申请日：2008-12-23

申请人： Zhiyong Li ,  Fung Suong Ou ,  William M. Tong

发明人： Zhiyong Li ,  Fung Suong Ou ,  William M. Tong

IPC分类号： G11C11/56 ,  H01L45/00

CPC分类号： G11C13/0011 ,  B82Y10/00 ,  G11C11/56 ,  G11C13/00 ,  G11C13/0002 ,  G11C13/0069 ,  G11C13/02 ,  G11C13/025 ,  G11C2013/009 ,  G11C2213/35 ,  G11C2213/55 ,  G11C2213/56 ,  H01L45/08 ,  H01L45/1206 ,  H01L45/1226 ,  H01L45/1233 ,  H01L45/146

摘要： A memristive device (400) includes: a first electrode (405); a second electrode (425); a memristive matrix (415) interposed between the first electrode (405) and the second electrode (425); a porous dopant diffusion element (410) in physical contact with the memristive matrix (415) and in proximity to the first electrode (405) and the second electrode (425); and a first mobile dopant species which moves through the porous dopant diffusion element (410) in response to a programming electrical field. A method for using a memristive device (400) having a porous dopant diffusion element (410) includes applying a voltage bias to generate a programming electrical field such that dopants move through the porous dopant diffusion element (410), thereby changing the distribution of dopants within a memristive matrix (415) to form a first state; removing the voltage bias, the dopants being substantially immobile in the absence of the programming electrical field; and applying a reading energy to the memristive device (400) to sense the first state.

摘要翻译： 忆阻器（400）包括：第一电极（405）; 第二电极（425）; 插入在第一电极（405）和第二电极（425）之间的忆阻矩阵（415）; 与所述忆阻矩阵（415）物理接触并且接近所述第一电极（405）和所述第二电极（425）的多孔掺杂剂扩散元件（410）; 以及响应于编程电场而移动通过多孔掺杂剂扩散元件（410）的第一移动掺杂物种类。 使用具有多孔掺杂剂扩散元件（410）的忆阻器（400）的方法包括施加电压偏压以产生编程电场，使得掺杂剂通过多孔掺杂剂扩散元件（410）移动，由此改变掺杂剂的分布 在忆阻矩阵（415）内形成第一状态; 去除电压偏压，掺杂剂在没有编程电场的情况下基本上是不可移动的; 以及将读取能量施加到所述忆阻装置（400）以感测所述第一状态。

公开(公告)号：US07947485B2

公开(公告)日：2011-05-24

申请号：US11144586

申请日：2005-06-03

申请人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Philip J. Kuekes

发明人： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Philip J. Kuekes

IPC分类号： C12M1/00 ,  G01N15/06 ,  C07H21/04

CPC分类号： G01N33/48721 ,  B82Y5/00 ,  B82Y10/00 ,  G01N27/414

摘要： Devices and methods for detecting the constituent parts of biological polymers are disclosed. A molecular analysis device comprises a molecule sensor and a molecule guide. The molecule sensor comprises a single electron transistor including a first terminal, a second terminal, and a nanogap or at least one quantum dot positioned between the first terminal and the second terminal. A nitrogenous material disposed on the at least one quantum dot is configured for an interaction with an identifiable configuration of a molecule. The molecule sensor develops an electronic effect responsive to the interaction. The molecule guide is configured for guiding at least a portion of the molecule substantially near the molecule sensor to enable the interaction.

摘要翻译： 公开了用于检测生物聚合物的组成部分的装置和方法。 分子分析装置包括分子传感器和分子引导件。 分子传感器包括单电子晶体管，其包括位于第一端子和第二端子之间的第一端子，第二端子和纳米隙隙或至少一个量子点。 设置在至少一个量子点上的含氮材料被配置用于与分子的可识别构型的相互作用。 分子传感器产生响应于相互作用的电子效应。 分子引导件被配置用于基本上在分子传感器附近引导分子的至少一部分，以实现相互作用。

公开(公告)号：US20100325586A1

公开(公告)日：2010-12-23

申请号：US12487134

申请日：2009-06-18

申请人： Zhiyong Li ,  Rajesh Hotchandani ,  Austin Patrick Maher

发明人： Zhiyong Li ,  Rajesh Hotchandani ,  Austin Patrick Maher

IPC分类号： G06F3/048

CPC分类号： G06F3/0481

摘要： Computer-implemented systems and methods are provided for reducing a number of options presented to a user where the options have characteristics that are arranged in a multi-dimensional hierarchical space. A system and method can be configured to identify common dimensions using dimension nodes in dimensional points and identify compatible nodes for each dimension in the multi-dimensional hierarchical space by determining whether an association exists. Compatible pairs of surviving points are generated after applying each of the compatible nodes from the common dimensions. Greatest lower bounds (GLBs) are computed for each of the generated compatible points, and a set of options is generated comprising points from the generated compatible points and the computed GLBs.

摘要翻译： 提供了计算机实现的系统和方法，用于减少呈现给用户的多个选项，其中选项具有排列在多维层级空间中的特征。 可以将系统和方法配置为使用维度点中的维度节点来识别公共维度，并通过确定关联是否存在来识别多维分层空间中的每个维度的兼容节点。 在从普通维度应用每个兼容节点之后生成兼容的幸存点对。 为每个生成的兼容点计算最大下限（GLB），并且生成包括来自所生成的兼容点和计算出的GLB的点的一组选项。

公开(公告)号：US07805028B2

公开(公告)日：2010-09-28

申请号：US12253123

申请日：2008-10-16

申请人： Zhiyong Li ,  Michael Tan ,  Shih-Yuan Wang ,  Wei Wu ,  Jing Tang

发明人： Zhiyong Li ,  Michael Tan ,  Shih-Yuan Wang ,  Wei Wu ,  Jing Tang

IPC分类号： G02B6/00 ,  G02B6/32 ,  G02B6/10

CPC分类号： G02B6/02328 ,  B82Y20/00 ,  G01N21/05 ,  G01N21/31 ,  G01N21/645 ,  G01N21/658 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2021/6467 ,  G01N2021/7763 ,  G01N2021/7783 ,  G02B6/1226

摘要： An optical sensor, sensing system and method of sensing employ a half-core hollow optical waveguide adjacent to a surface of an optical waveguide layer of a substrate. The half-core hollow optical waveguide and the adjacent optical waveguide layer cooperatively provide both an optical path that confines and guides an optical signal and an internal hollow channel. The optical path and channel extend longitudinally along a hollow core of the half-core hollow optical waveguide. The system further includes an optical source at an input of the optical path and an optical detector at an output of the optical path. A spectroscopic interaction between an analyte material that is introduced into the channel and an optical signal propagating along the optical path determines a characteristic of the analyte material.

摘要翻译： 光学传感器，感测系统和感测方法使用与衬底的光波导层的表面相邻的半芯空心光波导。 半芯空心光波导和相邻的光波导层协同地提供限制和引导光信号和内部中空通道的光路。 光路和通道沿半芯空心光波导的中空芯纵向延伸。 该系统还包括在光路的输入处的光源和在光路的输出处的光学检测器。 引入到通道中的分析物质与沿光路传播的光信号之间的光谱相互作用决定了分析物质的特性。

公开(公告)号：US07741204B2

公开(公告)日：2010-06-22

申请号：US11590492

申请日：2006-10-30

申请人： Zhiyong Li ,  Warren Robinett

发明人： Zhiyong Li ,  Warren Robinett

IPC分类号： H01L21/44

CPC分类号： G11C5/06 ,  B82B1/00 ,  B82B3/00 ,  B82Y10/00 ,  B82Y40/00 ,  G11C5/12 ,  G11C2213/81 ,  H01L29/0665 ,  H01L29/0673 ,  H01L29/0676 ,  H01L29/068 ,  H01L51/0595 ,  Y10S977/762 ,  Y10S977/94

摘要： Certain embodiments of the present invention are directed to a method of fabricating a mixed-scale electronic interface. A substrate is provided with a first set of conductive elements. A first layer of nanowires may be formed over the first set of conductive elements. A number of channels may be formed, with each of the channels extending diagonally through a number of the nanowires of the first layer. A number of pads may be formed, each of which is electrically interconnected with an underlying conductive element of the first set of conductive elements and one or more adjacent nanowires of the first layer of nanowires. The pads and corresponding electrically interconnected nanowires define a number of pad-interconnected-nanowire-units. Additional embodiments are directed to a method of forming a nanoimprinting mold and a method of selectively programming nanowire-to-conductive element electrical connections.

摘要翻译： 本发明的某些实施例涉及一种制造混合比例电子接口的方法。 衬底设置有第一组导电元件。 可以在第一组导电元件上形成第一层纳米线。 可以形成多个通道，其中每个通道对角地延伸穿过第一层的多个纳米线。 可以形成多个焊盘，每个焊盘与第一组导电元件的下面的导电元件和第一纳米线层的一个或多个相邻的纳米线电互连。 焊盘和相应的电互连纳米线限定了多个衬垫互连的纳米线单元。 另外的实施例涉及形成纳米压印模具的方法和选择性地编程纳米线至导电元件电连接的方法。

公开(公告)号：US20100091274A1

公开(公告)日：2010-04-15

申请号：US12287549

申请日：2008-10-10

申请人： Alexandre M. Bratkovski ,  Ekaterina Viktorovna Ponizovskaya ,  Zhiyong Li

发明人： Alexandre M. Bratkovski ,  Ekaterina Viktorovna Ponizovskaya ,  Zhiyong Li

IPC分类号： G01J3/44 ,  G01N21/55

CPC分类号： G01N21/658

摘要： Various embodiments of the present invention relate to plasmonic electric-field concentrators and to systems incorporating the plasmonic electric-field concentrators to perform Raman spectroscopy. In one aspect, a plasmonic electric-field concentrator comprises two or more large features, and a relatively small feature similar in shape to large features positioned adjacent to the two or more large features. The features are arranged so that when light of an appropriate wavelength is incident on the features, surface plasmon polaritons form on the outer surfaces of the features. The surface plasmon polaritons have associated electric fields extending perpendicular to the surfaces of the features. The electric fields are concentrated in the space between features forming an electric field hot spot that enhances Raman scattered light emitted from an analyte proximate to or absorbed on the features.

摘要翻译： 本发明的各种实施例涉及等离子体电场集中器以及结合等离子体激元集中器以执行拉曼光谱的系统。 一方面，等离子体电场集中器包括两个或更多个大特征，以及与形状相邻的相对较小的特征，其尺寸与两个或更多个特征邻近的大特征相似。 特征被布置成使得当适当波长的光入射到特征上时，在特征的外表面上形成表面等离子体激元。 表面等离子体激元极化子具有垂直于特征表面延伸的相关电场。 电场集中在形成电场热点的特征之间的空间中，其增强了从附近或被吸收在特征上的分析物发射的拉曼散射光。

公开(公告)号：US20100020327A1

公开(公告)日：2010-01-28

申请号：US12262151

申请日：2008-10-30

申请人： David Fattal ,  Zhiyong Li

发明人： David Fattal ,  Zhiyong Li

IPC分类号： G01N21/55

CPC分类号： G01N21/658

摘要： A plasmonic conveyor, system and method of plasmonic conveyance employ a surface plasmon that is controllably moved on a surface of a plasmonic element. The conveyor includes a first plasmonic element and a second plasmonic element that individually supports a respective surface plasmon. The conveyor further includes a controller that provides controlled movement of a location of the respective surface plasmon on a surface of the plasmonic element. The controlled movement facilitates translocation of an analyte particle around a periphery of the respective plasmonic element using a high field region of the respective surface plasmon. The system includes the conveyor and an excitation signal source that provides an excitation signal having one or both of a polarization and a frequency that are controllably variable. The method includes exciting a surface plasmon with the excitation signal and moving a location of the excited surface plasmon.

摘要翻译： 等离子体激元输送机，等离子体激元传输的系统和方法采用可等离子体激元在等离子体元素表面上移动的表面等离子体激元。 输送机包括单独支撑相应的表面等离子体激元的第一等离子体元素和第二等离子体元素。 输送机还包括一个控制器，该控制器提供相应表面等离子体的位置的受控运动在等离子体元素的表面上。 受控运动有助于使用相应表面等离子体激元的高场区域使分析物质绕相应等离子体元素周围的位移。 该系统包括输送机和激励信号源，其提供具有可控地变化的偏振和频率中的一个或两个的激励信号。 该方法包括用激发信号激发表面等离子体激元并移动受激表面等离子体的位置。