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公开(公告)号:US20130234432A1
公开(公告)日:2013-09-12
申请号:US13686260
申请日:2012-11-27
发明人: Craig Graham
IPC分类号: F16L21/00
CPC分类号: F16L37/244 , B01L3/502715 , B01L3/563 , B01L2200/025 , B01L2200/027 , B01L2200/0631 , B01L2200/0689 , B01L2300/0832 , B01L2300/0851 , F16L15/08 , F16L19/0237 , F16L19/065 , F16L21/00 , G01N30/6026 , G01N30/6095 , G01N30/88 , Y10T29/49826
摘要: A microfluidic interconnect system and method for assembly thereof is described. The microfluidic interconnect has a port and a seal, with the port having a reverse taper. The port has a first port end, a second port end, and an inner port surface with a tapered portion. Each port end has an opening with a diameter, and in certain embodiments, the diameter of the first port end is smaller than the diameter of the second port end. The seal has a first end and a second end, and each seal end has a rim and an opening with an inner diameter and an outer diameter. The seal also has an inner surface and an outer surface, where in certain embodiments, each surface has a tapered portion. In certain embodiments, the inner diameter of the first seal end is equal to or larger than the inner diameter of the second seal end, the outer diameter of the first seal end is equal to or smaller than the outer diameter of the second seal end, and the outer diameter of the second seal end is larger than the outer diameter of each port end. In certain embodiments, a tube is slidably coupled to the inner surface of the seal, and the tube has an outer diameter that is equal to or larger than the inner diameter of the second seal end.
摘要翻译: 描述了一种微流控互连系统及其装配方法。 微流体互连具有端口和密封,端口具有倒锥度。 该端口具有第一端口端,第二端口端和具有锥形部分的内端口表面。 每个端口端部具有直径的开口,在某些实施例中,第一端口的直径小于第二端口的直径。 密封件具有第一端和第二端,并且每个密封端具有边缘和具有内径和外径的开口。 密封件还具有内表面和外表面,其中在某些实施例中,每个表面具有锥形部分。 在某些实施例中,第一密封端的内径等于或大于第二密封端的内径,第一密封端的外径等于或小于第二密封端的外径, 并且第二密封端的外径大于每个端口的外径。 在某些实施例中,管可滑动地联接到密封件的内表面,并且管具有等于或大于第二密封端的内径的外径。
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公开(公告)号:US08528592B2
公开(公告)日:2013-09-10
申请号:US12932493
申请日:2011-02-28
申请人: Zhenxing Dong
发明人: Zhenxing Dong
IPC分类号: F16K15/04
CPC分类号: F16K27/0245 , F04B53/1002 , F16K15/048 , Y10T137/7838 , Y10T137/791
摘要: A check valve construction is provided in which a moveable a movable ball having a convex surface resides in a cage having a conical frustum chamber and a seat for the ball. A fluid path between the ball and the cage is defined by the equation: G = D cos ( b - a ) 2 cos b - d 2 wherein G is the gap of the narrowest passageway of the fluid path, D is the diameter of the small end of the conical frustum chamber of the cage, d is the diameter of the convex surface of the ball, a is the angle between a vertical diameter of the ball and the position of the narrowest gap on the convex surface of the ball, and, b is the angle between the vertical diameter of the movable element and the position of the small end of conical frustum chamber of the cage.
摘要翻译: 提供了一种止回阀结构,其中具有凸表面的可移动的可移动球体位于具有锥形截头锥体室和用于球的座的保持架中。 球和保持架之间的流体通道由下列公式定义:G = D·吐函数(b-a)2d wherein wherein wherein wherein wherein wherein wherein wherein wherein wherein wherein wherein ,D是保持架的锥形截头锥室的小端的直径,d是球的凸面的直径,a是球的垂直直径与最小间隙的位置之间的角度 球的凸面,b是可动元件的垂直直径与保持架的锥形截头锥体的小端的位置之间的角度。
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公开(公告)号:US20130227831A1
公开(公告)日:2013-09-05
申请号:US13411352
申请日:2012-03-02
申请人: Nathaniel Nienhuis
发明人: Nathaniel Nienhuis
CPC分类号: F16L15/04 , B01L3/563 , B01L3/565 , B01L2300/0838 , F16L19/00 , G01N30/6004 , G01N30/6026 , G01N30/6039
摘要: A fitting assembly is provided having a nut and a ferrule, which in certain embodiments may be assembled by an operator. The nut and ferrule of the fitting assembly have passageways therethrough for receiving and removably holding tubing. The nut and ferrule fitting assembly may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.
摘要翻译: 提供了具有螺母和套圈的配件组件,其在某些实施例中可由操作者组装。 配件组件的螺母和套管具有穿过其的通道,用于接收和可移除地保持管道。 螺母和套圈配件组件可以适用于平底端口,例如在分析仪器中,如液相色谱,气相色谱,离子色谱或体外诊断系统。
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公开(公告)号:US20120024411A1
公开(公告)日:2012-02-02
申请号:US13206873
申请日:2011-08-10
申请人: Mark Hahn , Scott J. Ellis , Eric Beemer
发明人: Mark Hahn , Scott J. Ellis , Eric Beemer
CPC分类号: F16L9/147 , B01D15/22 , F16L9/14 , F16L19/041 , F16L58/10 , G01N30/6004 , G01N30/6026 , G01N30/6039 , G01N30/6073 , Y10T29/49826
摘要: A biocompatible tube that can be used in a liquid chromatography system is described. The tube can have flanged or straight ends, and can be used in conjunction with one or more fitting, assembly.
摘要翻译: 描述了可用于液相色谱系统的生物相容性管。 管可以具有凸缘或直的端部,并且可以与一个或多个配件组装一起使用。
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公开(公告)号:USD630710S1
公开(公告)日:2011-01-11
申请号:US29321095
申请日:2008-07-10
申请人: Caitlin McEathron
设计人: Caitlin McEathron
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公开(公告)号:US11703485B2
公开(公告)日:2023-07-18
申请号:US17235444
申请日:2021-04-20
发明人: David Medeiros , Scott Ellis , Eric Beemer , Jason Polly
CPC分类号: G01N30/32 , F04B19/04 , F04B53/16 , G01N2030/326
摘要: A structural reinforcement and biocompatible pump head for a pump includes a reinforcement structure having a plurality of ports and fluid pathways therein. The fluid pathways in the reinforcement may be coated or lined with a biocompatible material to form a biocompatible pump head useful for liquid chromatography and other analytical instrument systems. The biocompatible material may be injection molded into the fluid pathways of the reinforcement structure and may be machined after core pins are removed to obtain a desired surface finish and/or size of the biocompatible fluid pathways of the pump head.
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公开(公告)号:US11526001B2
公开(公告)日:2022-12-13
申请号:US16557384
申请日:2019-08-30
IPC分类号: G02B26/08 , H01S3/23 , G02B27/10 , G02B27/14 , G02B27/30 , H01S3/02 , H01S3/04 , G01N21/64 , H01S3/00
摘要: Various embodiments of a multi-laser system are disclosed. In some embodiments, the multi-laser system includes a plurality of lasers, a plurality of laser beams, a beam positioning system, a thermally stable enclosure, and a temperature controller. The thermally stable enclosure is substantially made of a material with high thermal conductivity such as at least 5 W/(m K). The thermally stable enclosure can help maintain alignment of the laser beams to a target object over a range of ambient temperatures. Various embodiments of an optical system for directing light for optical measurements such laser-induced fluorescence and spectroscopic analysis are disclosed. In some embodiments, the optical system includes a thermally conductive housing and a thermoelectric controller, a plurality of optical fibers, and one or more optical elements to direct light emitted by the optical fibers to illuminate a flow cell. The housing is configured to attach to a flow cell.
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公开(公告)号:US11054054B2
公开(公告)日:2021-07-06
申请号:US15962748
申请日:2018-04-25
发明人: Quan Liu , Jeremy Hayes
IPC分类号: G01N30/20 , F16K31/04 , F16K25/00 , F16K11/074 , B01D15/22
摘要: A valve for use with liquid chromatography or other analytical systems may include a separate and removable stator plate. The stator plate may be a with a multi-piece stator plate with different layers. A mounting device mounting device may be adapted to engage the stator plate. The mounting plate may include a plurality of ports for fluidic connections in fluid communication with fluid passageways in the stator plate. Liquid chromatography elements, such as a packed chromatography column, a sample loop, or an electronic device may be formed on one or more layers of the stator plate. A first stator plate may be removed from a valve and replaced by a second stator having additional or different liquid chromatography elements than the first stator plate.
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公开(公告)号:US10962146B2
公开(公告)日:2021-03-30
申请号:US15796385
申请日:2017-10-27
发明人: Mark Hahn , Scott J. Ellis , Eric Beemer
摘要: A biocompatible tube and fitting system that can be used in a liquid chromatography system is described. The tube can have a polymer tip and can be used in conjunction with one or more fitting assembly.
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公开(公告)号:US20210086105A1
公开(公告)日:2021-03-25
申请号:US17028171
申请日:2020-09-22
IPC分类号: B01D19/00
摘要: The pressure fluctuations in a fluid degassing system may be diminished by independently controlling the intake phase and the exhaust phase of an evacuation pump. The speed of the pump's drive element may be modulated at least during the intake phase to more closely align with a pressure set point in a degassing module.
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