Abstract:
The degree of phosphorylation of serine and threonine residues of p100/p120 can affect the permeability of physiological barriers and also cell—cell adhesion properties. By changing physiological levels, various disorders can be treated, including multiple sclerosis, cancer, head injuries, oedema, stroke, inflammation and gastric ulcers. Furthermore, drugs can be allowed to pass across physiological barriers and the barriers can then be closed.
Abstract:
A surface mount, tunable inductor (200) includes a core (205) that is substantially toroidal in shape. The core (205) has a first flattened surface (206) and a second flattened surface (207) opposite the first flattened surface (206), and a hole (208) is formed through the core (205). A wire (210) is wound about the core (205) and terminates in first and second leads (215). The inductor (200) also includes a substrate (220) on which first and second conductive pads (225) are formed. Each of the wire leads (215) is electrically coupled to one of the conductive pads (225), and an adhesive (240) secures the first flattened surface (207) of the core (205) to the substrate (220).
Abstract:
A protein, p100, is disclosed having a molecular weight of about 100 kDa, being associated in vivo with catenin-cadherin complex of epithelial or endothelial cells, and having cross-reactivity with an antibody to the p120 protein involved in cell-cell adhesion. Also disclosed is a method to treat a cancer or developmental disorder characterized by compromised cell-cell adhesion.
Abstract:
An injector is described which comprises a valve element engageable with a seating, the valve element being resiliently biased into engagement with the seating. The valve element includes a thrust surface arranged, in use, to have high pressure fuel applied thereto to lift the valve element from the seating. A stop in the form of a second valve member is arranged to restrict movement of the valve element away from the seating, the second valve member being arranged to have high pressure fluid applied thereto and being movable under the influence of the valve element against the action of the high pressure fluid, in use.
Abstract:
Dyed cellulosic regenerated elongate members such as fibers are produced by dyeing the regenerated members with a cationic direct dye after formation but before first drying. A method of producing the dyed elongate members comprises forming a dope containing cellulose or a cellulose compound in solution in a solvent, extruding the dope through at least one orifice into a bath containing water to form an elongate extrudate from which solvent is dissolved and/or the cellulose compound is converted to cellulose so as to form the elongate member, dyeing the formed but never dried elongate member with a cationic direct dye and optionally also with an anionic direct dye and then drying for the first time the dyed elongate member.
Abstract:
A method for increasing the resistance of a light emitting diode and other semiconductor devices to extremes of temperature is disclosed. During the manufacture of the light emitting diode, a liquid coating is applied to the light emitting die after the die has been placed in its lead frame. After the liquid coating has been placed on the die and its lead frames, a thermosetting encapsulant material is placed over the coating. The operation that cures the thermosetting material leaves the coating liquid intact. As the die and the encapsulant expand and contract at different rates with respect to changes in temperature, and as in known light emitting diodes the encapsulating material adheres to the die and lead frames, this liquid coating reduces the stresses that these different rates of expansion and contraction normally cause by eliminating the adherence of the encapsulating material to the die and frame.
Abstract:
A dental floss dispenser that includes a body having a cavity for holding a spool of the dental floss and a cover removably mounted on the body providing access to the cavity. There is an outlet hole in the body member for pulling therethrough the string of the dental floss. There are a series of side-by-side slots in walls of the body that extend across the top wall and a longitudinal cutting edge on a knife located within the body is exposed in respective ones of the slots.
Abstract:
Apparatus for metering fuel and air for an engine, which apparatus comprises air flow measuring means which measures at least a part of the flow of air for the engine and which generates an electrical output that is proportional to the measured air flow, control means which receives the output from the air flow measuring means and which generates electrical output signals which vary in dependence upon the received signals, and an injector which injects fuel in response to the signals from the control means. Preferably the apparatus of the invention includes fuel dissipating means, such as a heat pipe or a sonic nozzle, for finely atomizing the injected fuel.
Abstract:
A fuel injection nozzle arrangement comprising a fuel injection nozzle having a fuel injection orifice, and vibratory means such as a piezoelectric crystal for vibrating the nozzle to cause atomization of fuel ejected from the nozzle through the orifice, the nozzle having a fuel-retaining valve at the fuel inlet side of the orifice arranged to normally close the orifice and thus prevent the injection of fuel but to be opened when the vibratory means is energised to permit injection of fuel, and the nozzle having a gas-excluding valve at the fuel outlet side of the orifice arranged to normally close the orifice and thus prevent the entry of gases into the nozzle through the orifice but to open under fuel injection pressure to permit the injection of fuel.
Abstract:
A vibratory fuel atomizer in which a small housing is located within the atomizer near the atomizer tip, the housing containing a ball valve for shutting off the flow of fuel and a spring for biasing the ball valve to the closed position.