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公开(公告)号：US20250143822A1
公开(公告)日：2025-05-08
申请号：US19014150
申请日：2025-01-08
Inventor： WENKE DUAN , OLATUNJI MUMINI OMISORE , LEI WANG
Abstract: The present disclosure relates to a robotic system for respiratory diagnosis and treatment and a control method therefor. The present disclosure includes a master control apparatus for operating and controlling a control instruction, a slave control apparatus for receiving the control instruction of the master control apparatus and operating an operation action, and a navigation apparatus for guiding the slave control apparatus. The slave control apparatus includes a slave robot and a slave embedded controller installed inside the slave robot. The slave robot is provided with a mechanical arm, a propulsion support plate connected to the mechanical arm, a biopsy instrument introduction mechanism connected to a propulsion support plate for delivering a biopsy instrument, a bronchoscope rotation driving mechanism for controlling a bronchoscope, and a bending control mechanism for controlling an angle of a flexible end of the bronchoscope.
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公开(公告)号：US20250137909A1
公开(公告)日：2025-05-01
申请号：US19004464
申请日：2024-12-30
Inventor： LONG MENG , WEI ZHOU , HAIRONG ZHENG , LILI NIU , BENXIAN PENG
IPC: G01N15/149 , G01N15/10 , G01N15/14 , G01N15/1404
Abstract: A cellular mechanical property measurement and sorting method comprises: cells to be sorted being arranged in a straight line after passing through a standing wave acoustic field generated by a first interdigital transducer; the cells flowing through a focused acoustic field generated by a second interdigital transducer, and the focused acoustic field generating a radiation force on the cells, such that the cells are deformed; performing calculation according to information of the radiation force and deformation, so as to obtain elastic moduli of the cells; determining the positions of the cells, and selectively driving, with designed delay time, interdigital transducers in a cell sorting unit according to the moving speeds of the cells and the distances between the cells and the sorting unit, and triggering, according to the elastic moduli, a corresponding interdigital transducer to generate a planar acoustic field, so as to sort the cells.
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公开(公告)号：US12254684B2
公开(公告)日：2025-03-18
申请号：US17763513
申请日：2019-11-19
Inventor： Shuqiang Wang , Wen Yu , Yanyan Shen , Zhuo Chen
Abstract: The present application is suitable for use in the technical field of computers, and provides a smart diagnosis assistance method and terminal based on medical images, comprising: acquiring a medical image to be classified; pre-processing the medical image to be classified to obtain a pre-processed image; and inputting the pre-processed image into a trained classification model for classification processing to obtain a classification type corresponding to the pre-processed image, the classification model comprising tensorized network layers and a second-order pooling module. As the trained classification model comprises tensor decomposed network layers and a second-order pooling module, when processing images on the basis of the classification model, more discriminative features related to pathologies can be extracted, increasing the accuracy of medical image classification.
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公开(公告)号：US20250040827A1
公开(公告)日：2025-02-06
申请号：US18921953
申请日：2024-10-21
Inventor： Ye LI , Zhiguang MO , Xiaoping ZHANG , Huageng LIANG , Chao LUO , Qiaoyan CHEN , Changjun TIE , Qi CAO , Wen XIAO
Abstract: A multichannel endorectal coil for prostate MRI, a system, and a working method. The coil comprises a support body provided with a winding curved surface, a plurality of first endorectal coils (1, 2, 3) wrapped around the surface of the support body, and a second endorectal coil stacked on the plurality of first endorectal coils (1, 2, 3); wherein two adjacent first endorectal coils (1, 2, 3) are decoupled by means of partial overlapping, and two non-adjacent first endorectal coils (1, 2, 3) are decoupled by providing a shared capacitor (5); the second endorectal coil comprises a first coil section and a second coil section which are in intersecting connection with one another, the first coil section and the second coil section are arranged symmetrically, and no electrical connection exists at the intersection thereof. The invention increases the number of channels, and further achieves better high-resolution imaging capabilities.
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公开(公告)号：US12208242B2
公开(公告)日：2025-01-28
申请号：US17312950
申请日：2020-11-13
Inventor： Zedong Nie , Jingzhen Li , Yuhang Liu
Abstract: A closed-loop artificial pancreas system based on a wearable monitoring method is provided. The system includes: a wearable blood glucose monitoring submodule, configured to obtain a blood glucose sensing signal in a noninvasive manner by utilizing a wearable device; a diet and exercise monitoring submodule, configured to obtain diet monitoring data and exercise monitoring data which can cause variations of blood glucose concentration of a subject to be tested; a calculation control submodule, configured to obtain information related to insulin infusion by utilizing a trained deep learning model, the diet monitoring data, and the exercise monitoring data; an insulin infusion submodule, configured to automatically implement insulin infusion; and an effect assessment module, configured to assess an insulin infusion effect, and to feed an assessment result back to the calculation control submodule, such that the calculation control submodule determines whether to update the information related to insulin infusion.
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Patent Agency Ranking
86.发明公开公开(公告)号：US20240342268A1
公开(公告)日：2024-10-17
申请号：US18682494
申请日：2022-08-04
Inventor： Longlong SI
IPC: A61K39/145 , A61K39/00 , A61P37/04 , C07K14/005 , C12N15/86
CPC classification number: A61K39/145 , A61P37/04 , C07K14/005 , C12N15/86 , A61K2039/5254 , A61K2039/5256 , A61K2039/543 , C07K2319/95 , C12N2760/16122 , C12N2760/16134 , C12N2760/16143 , C12N2760/16152 , C12N2760/16162 , C12N2760/16171
Abstract: A recombinant virus containing a degron, a preparation method therefor, and an application thereof. At least one viral protein of the recombinant virus containing the degron contains at least one degron capable of being recognized by a protein degradation system of a host cell, wherein the degron comprises any one of or a combination of at least two of an amino acid sequence, a polypeptide, or a structural motif. Further provided are a nucleic acid molecule, a recombinant vector, a preparation method for the recombinant virus containing the degron, a preparation system for the recombinant virus containing the degron, a vaccine, an oncolytic virus, and a drug. The recombinant virus containing the degron can be recognized and degraded by the protein degradation system in the host cell, the replication capability is weakened or even removed, and after a corresponding vaccine, oncolytic virus or drug is prepared, a good effect and practical application value are achieved.
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公开(公告)号：US20240320833A1
公开(公告)日：2024-09-26
申请号：US18199377
申请日：2023-05-19
Inventor： Yingying HAN , Ying HU , Baoliang ZHAO , Yuxin SONG , Ziwen WANG , Peng ZHANG
CPC classification number: G06T7/0016 , G06T7/11 , G06T2207/10132
Abstract: An ultrasonic image quality quantitative evaluation method includes segmenting a focus area aiming at a target ultrasonic image to extract a region of interest and perform a masking operation to acquire an image segmentation result mask; taking the image segmentation result mask as a reference image, and quantitatively comparing the reference image with a corresponding focus area according to a set evaluation standard to acquire a plurality of evaluation result indexes; and inputting the plurality of evaluation result indexes as an image feature into a classifier to acquire a quality quantification result of the focus area of the target ultrasonic image, where the classifier takes the plurality of evaluation result indexes corresponding to a sample image as an input feature, takes an image quality label of the labeled focus area as an output, and acquires the quality quantification result through training based on a set loss function.
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公开(公告)号：US12092714B2
公开(公告)日：2024-09-17
申请号：US17992868
申请日：2022-11-22
Inventor： Hairong Zheng , Qiaoyan Chen , Ye Li , Chao Luo , Xin Liu
IPC: G01R33/3875 , A61B5/055
CPC classification number: G01R33/3875 , A61B5/055
Abstract: A shimming method and device, an electronic device, and a storage medium are disclosed. The shimming method includes: obtaining object static magnetic field distribution information corresponding to a target object, the object static magnetic field distribution information including the static magnetic field distribution information of the target object under the action of a main magnet of a magnetic resonance system; determining a target static magnetic field based on the object static magnetic field distribution information and a preset shim coil magnetic field distribution model; and adjusting at least one shim coil parameter in the shim coil magnetic field distribution model until a magnetic field uniformity of the target static magnetic field satisfies a preset condition, and accordingly obtaining at least one target shim coil parameter.
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89.发明公开公开(公告)号：US20240181080A1
公开(公告)日：2024-06-06
申请号：US18434358
申请日：2024-02-06
Inventor： Yingzi ZHAO , Botai LI , Dashuang GAO , Fan YANG
IPC: A61K48/00 , A61K31/5513 , A61K38/17 , A61P19/08 , C12N15/86
CPC classification number: A61K48/005 , A61K31/5513 , A61K38/177 , A61P19/08 , C12N15/86 , C12N2740/15043 , C12N2750/14143
Abstract: Disclosed in the present invention is A method for controlling heterogeneity of vascular endothelial cells by utilizing sympathetic nerves is provided, comprising expressing an artificial designer protein receptor exclusively activated by a designer drug in neuron cells, and then activating the artificial designer protein receptor by the designer drug, thereby activating or inhibiting neuronal activity to achieve control of the heterogeneity of the vascular endothelial cells. The method enables local modulation of the sympathetic nervous activity, thereby controlling the heterogeneity of the vascular endothelial cells, and can achieve bidirectional modulation. According to the present invention, the heterogeneity of bone vascular endothelial cells is controlled by manipulating the sympathetic nerves, such that the subtype of the bone vascular endothelial cells is controlled, thereby affecting the bone mineral density coupled therewith. The present invention has important clinical significance in the field of treatment or prevention of osteoporosis.
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公开(公告)号：US11875126B2
公开(公告)日：2024-01-16
申请号：US17367883
申请日：2021-07-06
Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY, CHINESE ACADEMY OF SCIENCES , TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
Inventor： Min Yang , Wei Bi , Xiao Jiang Liu , Lei Chen , Ting Ting Huang
Abstract: A method for training a dialog generation model includes: acquiring a dialog data set, and encoding a post in the dialog data set by using an encoder in the dialog generation model to obtain an encoded representation of the post; fusing, by using a decoder in the dialog generation model, the encoded representation of the post and knowledge information corresponding to the post that is obtained from a knowledge base question answering model through transfer learning to obtain a predicted response corresponding to the post; determining a value of a loss function of the dialog generation model based on the predicted response and the annotated response that correspond to the post; and updating a model parameter of the dialog generation model based on the value of the loss function. A method, an apparatus, a device, and a computer storage medium for generating a dialog are also provided.
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