公开(公告)号：US20230295639A1

公开(公告)日：2023-09-21

申请号：US18155179

申请日：2023-01-17

Applicant: University of Washington

Inventor： Christoffer NORN ,  Ivan ANISHCHANKA ,  David BAKER ,  Sam PELLOCK ,  Douglas TISCHER ,  Hsien-Wei YEH

IPC: C12N15/62 ,  C12N15/63 ,  C12N15/10

CPC classification number: C12N15/62 ,  C12N15/1044 ,  C12N15/63

Abstract: Polypeptide are disclosed that comprise an amino acid sequence at least 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NO:1-1615, not including any functional domains added fused to the protein (whether N-terminal, C-terminal, or internal), and wherein the 1, 2, 3, 4, or 5 N-terminal and/or C-terminal amino acid residues may be present or absent when considering the percent identity.

公开(公告)号：US20230292762A1

公开(公告)日：2023-09-21

申请号：US18120319

申请日：2023-03-10

Applicant: INTRINSYX BIO INC. ,  University of Washington

Inventor： John L. Freeman III ,  Douglas Baker ,  Nigel Grech ,  William John Haywood ,  Sharon L. Doty

IPC: A01N63/20 ,  A01N57/20 ,  A01P21/00 ,  A01P13/00 ,  C05F11/08

CPC classification number: A01N63/20 ,  A01N57/20 ,  A01P21/00 ,  A01P13/00 ,  C05F11/08

Abstract: Endophyte inoculant compositions, methods of making such compositions, methods of using such compositions, and physiologically altered plants treating with such compositions are disclosed. The endophyte inoculant composition may include one or more of endophyte strains WW5, WW6, WW7, and PTD1, which promote plant mineral nutrient acquisition and uptake, vigor, health, growth, and yield when applied to non-native host plants.

公开(公告)号：US20230287402A1

公开(公告)日：2023-09-14

申请号：US18040684

申请日：2021-08-23

Applicant: University of Washington ,  MEDICAL RESEARCH COUNCIL, AS PART OF UNITED KINGDOM RESEARCH AND INNOVATION

Inventor： Ariel Ben SASSON ,  David BAKER ,  William SHEFFLER ,  Hannele RUOHOLA-BAKER ,  Logeshwaran SOMASUNDARM ,  Emmanuel DERIVERY ,  Joseph WATSON

IPC: C12N15/11 ,  C12N15/63

CPC classification number: C12N15/11 ,  C12N15/63

Abstract: The disclosure provides two-dimensional protein structures including first and second polypeptides that are different, each form homo-oligomers, and interact to form a rigid interface, polypeptide components of such two-dimensional protein structures, and uses thereof.

公开(公告)号：US20230272462A1

公开(公告)日：2023-08-31

申请号：US18004489

申请日：2021-07-09

Applicant: UNIVERSITY OF WASHINGTON

Inventor： Enos Kline ,  Michael Roller ,  Robert G. Atkinson ,  Nuttada Panpradist ,  Daniel Leon ,  Ian Hull ,  Qin Wang ,  Barry R. Lutz

IPC: C12Q1/6844 ,  C12Q1/6883 ,  C12N15/63 ,  B01L7/00

CPC classification number: C12Q1/6844 ,  C12Q1/6883 ,  C12N15/63 ,  B01L7/52 ,  C12N2310/122 ,  B01L2300/1822

Abstract: Kits, methods, polypeptides, systems, and non-transitory, machine-readable storage media for detecting a nucleic acid in a sample are described. In an embodiment, the kit comprises a loop primer nucleic acid molecule configured for loop-mediated isothermal amplification (LAMP), the loop primer nucleic acid molecule comprising: a targeting sequence complementary to a target portion of a target nucleic acid sequence; and an adapter sequence; a displacement nucleic acid probe comprising: a fluorophore adapter sequence; and the adapter sequence; and a fluorophore adapter complement nucleic acid molecule complementary to the fluorophore adapter sequence, wherein the fluorophore adapter sequence or the fluorophore adapter complement nucleic acid molecule is coupled to a fluorophore. In an embodiment, the system comprises a thermal subsystem for heating a sample disposed therein, and an optical subsystem for optically excited the sample and detecting light emitted from the sample.

公开(公告)号：US11728038B2

公开(公告)日：2023-08-15

申请号：US16497513

申请日：2018-04-06

Applicant: Oregon Health & Science University ,  University of Washington

Inventor： Charles Springer ,  Gregory Wilson ,  Jeffrey Maki ,  Thomas Barbara ,  Xin Li ,  William Rooney ,  Wei Huang ,  Brendan Moloney ,  Eric Baker

IPC: G16H50/50 ,  G16H30/20 ,  G01R33/563

CPC classification number: G16H50/50 ,  G01R33/56341 ,  G16H30/20

Abstract: Methods, computer-readable storage media and systems are described for constructing a three-dimensional electronic library of simulated decays of the diffusion-weighted 1H2O MR signal in b-space. Methods, computer-readable media, and systems are described for preparing a parametric tissue map for tissue in a subject. Computer readable media, having an electronic library of simulated decays of the diffusion-weighted 1H2O signal in b-space and method of using such a library.

公开(公告)号：US20230252913A1

公开(公告)日：2023-08-10

申请号：US18167629

申请日：2023-02-10

Applicant: University of Washington

Inventor： Shahram Aarabi ,  Jason Germany ,  Abhijith Shasheendra ,  Ketan Sunil Mhetre

IPC: G09B23/34 ,  G01K7/02 ,  G01K13/10 ,  G01N25/32

CPC classification number: G09B23/34 ,  G01K7/021 ,  G01K13/10 ,  G01N25/32 ,  G01K2213/00

Abstract: A thermally representative phantom mammalian manikin assembly is provided. The assembly can include a cover portion representative of mammalian tissue partially enclosing a thermal cavity having a thermally representative material therein. The cover portion can have an opening with a cap extending across the opening and configured to further enclose the thermal cavity. The cap can have an aperture extending therethrough to receive a device extending through the aperture and into the thermally representative material within the thermal cavity. The device can be a thermocouple configured to measure a temperature of the thermally representative material. In assemblies representing mammalian limbs, the assembly can further include a second thermal cavity representing an additional portion of the limb, e.g., thermally representative upper and lower leg cavities.

公开(公告)号：USD994893S1

公开(公告)日：2023-08-08

申请号：US29754409

申请日：2020-10-09

Applicant: University of Washington

Designer： Larry Kessler ,  Sang-Gyeun Ahn ,  Ji-Eun Kim ,  Jeremy Barribeau

Abstract: FIG. 1 is a top front left perspective view of a portable medical device in accordance with our new design;
FIG. 2 is bottom rear right perspective view thereof;
FIG. 3 is a front elevation view thereof;
FIG. 4 is a rear elevation view thereof;
FIG. 5 is a top plan view thereof;
FIG. 6 is a bottom plan view thereof;
FIG. 7 is a left side elevation view thereof; and,
FIG. 8 is a right side elevation view thereof.

公开(公告)号：US11722017B2

公开(公告)日：2023-08-08

申请号：US17376861

申请日：2021-07-15

Applicant: University of Washington through its Center for Commercialization

Inventor： Joshua R. Smith ,  Benjamin H. Waters ,  Scott Wisdom ,  Alanson P. Sample

IPC: H02J50/90 ,  H02J50/12 ,  H03H7/40 ,  A61M60/216 ,  A61M60/873 ,  A61M60/523 ,  A61M60/538 ,  A61M60/178 ,  A61M60/148

CPC classification number: H02J50/90 ,  A61M60/178 ,  A61M60/216 ,  A61M60/523 ,  A61M60/538 ,  A61M60/873 ,  H02J50/12 ,  A61M60/148 ,  A61M2205/04 ,  A61M2205/3515 ,  A61M2205/3523 ,  A61M2205/3561 ,  A61M2205/8243 ,  H03H7/40

Abstract: An adaptive system for efficient and long-range wireless power delivery using magnetically coupled resonators responds to changes in a dynamic environment, and maintains high efficiency over a narrow or fixed frequency range. The system uses adaptive impedance matching to maintain high efficiency. The wireless power transfer system includes a drive inductor coupled to a high-Q transmitter coil, and a load inductor coupled to a high-Q receiver coil. The transmitter coil and receiver coil for a magnetically coupled resonator. A first matching network is (i) operably coupled to the drive inductor and configured to selectively adjust the impedance between the drive inductor and the transmitter coil, or (ii) is operably coupled to the load inductor and configured to selectively adjust the impedance between the load inductor and the receiver coil.

公开(公告)号：US11707483B2

公开(公告)日：2023-07-25

申请号：US16579662

申请日：2019-09-23

Applicant: University of Washington ,  GENEVANT SCIENCES GMBH

Inventor： Patrick S. Stayton ,  Allan S. Hoffman ,  Anthony Convertine ,  Craig L. Duvall ,  Danielle Benoit ,  Robert Overell ,  Paul H. Johnson ,  Anna S. Gall ,  Mary G. Prieve ,  Amber E. E. Paschal ,  Charbel Diab ,  Priyadarsi De

IPC: A61K31/713 ,  A61K9/107 ,  C08F290/06 ,  C08F293/00 ,  C12N15/11 ,  C12N15/87 ,  A61K47/69 ,  A61K47/58 ,  A61K47/54 ,  A61K47/60 ,  A61K48/00

CPC classification number: A61K31/713 ,  A61K9/1075 ,  A61K47/549 ,  A61K47/58 ,  A61K47/60 ,  A61K47/6907 ,  A61K48/0041 ,  C08F290/062 ,  C08F293/005 ,  C12N15/111 ,  C12N15/87 ,  C12N2320/32 ,  Y02A50/30

Abstract: Provided herein are micellic assemblies comprising a plurality of copolymers. In certain instauces, micellic assemblies provided herein are pH sensitive particles.

公开(公告)号：US20230227891A1

公开(公告)日：2023-07-20

申请号：US18158487

申请日：2023-01-24

Applicant: University of Washington

Inventor： Georg Seelig ,  Richard Muscat ,  Alexander B. Rosenberg

IPC: C12Q1/6806 ,  C12Q1/6855

CPC classification number: C12Q1/6806 ,  C12Q1/6855

Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.