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88 条记录 (耗时 0.03 秒)

    Nucleotide sequences coding for the pknD gene
    82.
    发明授权
    Nucleotide sequences coding for the pknD gene 失效

    公开(公告)号：US06927052B2

    公开(公告)日：2005-08-09

    申请号：US09949971

    申请日：2001-09-12

    申请人： Brigitte Bathe ,  Indra Schroeder ,  Mike Farwick ,  Thomas Hermann

    发明人： Brigitte Bathe ,  Indra Schroeder ,  Mike Farwick ,  Thomas Hermann

    IPC分类号： C12N9/12 ,  C12N9/00 ,  C07H21/04 ,  C12N1/20 ,  C12N9/10 ,  C12N15/00

    CPC分类号： C12N9/1205 ,  C12R1/15

    摘要： An isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising: (a) a polynucleotide which is at least 70% identical to a polynucleotide coding for a polypeptide containing the amino acid sequence of SEQ ID No. 2, (b) a polynucleotide coding for a polypeptide containing an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID No. 2, (c) a polynucleotide which is complementary to the polynucleotides of (a) or (b), and (d) a polynucleotide containing at least 15 consecutive nucleotides of the polynucleotide sequence of (a), (b), or (c), and a fermentation process for the preparation of L-amino acids using corynebacteria in which at least the pknD gene is amplified, and to the use, as hybridization probes, of polynucleotides containing the sequences according to the invention.

    Methods of making L-amino acids in coryneform using the sigE gene
    84.
    发明授权
    Methods of making L-amino acids in coryneform using the sigE gene 失效
    使用sigE基因在棒状细胞中制备L-氨基酸的方法

    公开(公告)号：US06913908B2

    公开(公告)日：2005-07-05

    申请号：US09935757

    申请日：2001-08-24

    申请人： Bettina Möckel ,  Thoams Hermann ,  Mike Farwick ,  Michael Binder ,  Walter Pfefferle

    发明人： Bettina Möckel ,  Thoams Hermann ,  Mike Farwick ,  Michael Binder ,  Walter Pfefferle

    IPC分类号： C07K14/34 ,  C12P13/08 ,  C12P13/04

    CPC分类号： C12R1/15 ,  C07K14/34 ,  C12P13/08

    摘要： The present invention relates lo an isolated polynucleotide from Corynebacterium glutamicum comprising a polynucleotide sequence chosen from the group c insisting of (a) a polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID NO: 2; (b) a polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID NO: 2; (c) a polynucleotide which is complementary to the polynucleotides of(a) or (b), and (d) a polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of (a), (b), or (c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the sigE gene is present in enhanced form, and the use of polynucleotides which comprise the sequence according to the invention as hybridization probes.

    摘要翻译： 本发明涉及一种来自谷氨酸棒杆菌的分离的多核苷酸，其包含选自下组的多核苷酸序列，所述多核苷酸序列坚持：（a）与编码多肽的多核苷酸的程度相同的多核苷酸，所述多核苷酸包含氨基 SEQ ID NO：2的酸序列; （b）编码多肽的多核苷酸，其包含与SEQ ID NO：2的氨基酸序列至少70％的程度相同的氨基酸序列; （c）与（a）或（b）的多核苷酸互补的多核苷酸，和（d）包含（a），（b）或（c）的多核苷酸序列的至少15个连续核苷酸的多核苷酸， 以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少sigE基因以增强形式存在，以及使用包含根据本发明的序列的多核苷酸作为杂交探针。

    Nucleotide sequences coding for the citA gene
    85.
    发明申请
    Nucleotide sequences coding for the citA gene 有权
    编码citA基因的核苷酸序列

    公开(公告)号：US20050112664A1

    公开(公告)日：2005-05-26

    申请号：US10977474

    申请日：2004-11-01

    申请人： Bettina Mockel ,  Mike Farwick ,  Thomas Hermann ,  Achim Marx ,  Walter Pfefferle

    发明人： Bettina Mockel ,  Mike Farwick ,  Thomas Hermann ,  Achim Marx ,  Walter Pfefferle

    IPC分类号： A61K38/48 ,  C07K14/34 ,  C12N9/12 ,  C12P13/08 ,  C12Q1/68 ,  C07H21/04 ,  C12N1/21 ,  C12N9/10 ,  C12N15/74

    CPC分类号： C12N9/1205 ,  C07K14/34 ,  C12N9/10 ,  C12P13/04 ,  C12P13/06 ,  C12P13/08 ,  C12P13/10 ,  C12P13/12 ,  C12P13/14 ,  C12P13/20 ,  C12P13/222 ,  C12P13/225 ,  C12P13/227 ,  C12P13/24

    摘要： The invention relates to isolated polynucleotides comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which. comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the citA gene is present in attenuated form, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.

    摘要翻译： 本发明涉及分离的多核苷酸，其包含多核苷酸序列，所述多核苷酸序列选自a）多核苷酸，其与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同至少70％ ，b）编码多肽的多核苷酸。 包括与SEQ ID No.2的氨基酸序列至少70％的程度相同的氨基酸序列，c）与a）或b）的多核苷酸互补的多核苷酸，和d）包含在 a），b）或c）的多核苷酸序列的至少15个连续核苷酸，以及使用棒状细菌发酵制备L-氨基酸的方法，其中至少citA基因以减毒形式存在，以及使用 包含根据本发明的序列的多核苷酸作为杂交探针。