公开(公告)号：US5409928A

公开(公告)日：1995-04-25

申请号：US138113

申请日：1993-10-20

申请人： Hiroshi Kiyokawa ,  Satoshi Yamada ,  Keisuke Miyajima ,  Koji Edamatsu ,  Kunihiko Tatsumi ,  Takeshi Yamauchi ,  Kazumasa Kishi ,  Kunihiko Kiyono

发明人： Hiroshi Kiyokawa ,  Satoshi Yamada ,  Keisuke Miyajima ,  Koji Edamatsu ,  Kunihiko Tatsumi ,  Takeshi Yamauchi ,  Kazumasa Kishi ,  Kunihiko Kiyono

IPC分类号： C07D487/04 ,  A61K31/53

CPC分类号： C07D487/04

摘要： This invention provides a condensed pyrazole derivative of the Formula (1): ##STR1## (where A denotes CH or N, R.sup.0 and R.sup.3 denote same or different, a hydrogen atom or a lower alkyl group, R.sup.1 and R.sup.2 denote same or different, a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group or a halogen atom, m denotes 1 or 2, and n denotes 1, 2 or 3, provided that, when n is 2, two R.sup.2 may be connected to each other to form a lower alkylenedioxy group), or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of action of androgen, thereby being excellent in therapeutical effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long lasting of efficacy and high oral absorption.

摘要翻译： 本发明提供式（1）的缩合吡唑衍生物：其中A表示CH或N，R 0和R 3表示相同或不同的氢原子或低级烷基，R 1和R 2表示相同 或不同的是，氢原子，低级烷基，低级烷氧基，低级烷硫基，硝基或卤原子，m表示1或2，n表示1,2或3，条件是当n 是2，两个R 2可以彼此连接以形成低级亚烷基二氧基）或其药学上可接受的盐。 该衍生物或其盐在抑制雄激素作用的表达方面具有优异的作用，因此具有良好的前列腺肥大，前列腺癌等的治疗效果，并且具有长效的功效和高的口服吸收。

公开(公告)号：US5398187A

公开(公告)日：1995-03-14

申请号：US922857

申请日：1992-07-31

申请人： Satoshi Yamada ,  Kenji Matsumoto ,  Satoru Shiono

发明人： Satoshi Yamada ,  Kenji Matsumoto ,  Satoru Shiono

IPC分类号： G06F15/18 ,  G06G7/60 ,  G06N3/02 ,  G06N3/04 ,  G06N99/00 ,  G06F15/42

CPC分类号： G06N3/049

摘要： The present invention provides an interneuron crossrelation identification technique and an interneuron connection-structure estimation technique for inferring a connection-structure and the strengths of the connectivities among a plurality of neurons required for constructing a neural network model, by obtaining crossrelations among time-course data of neurons. The interneuron crossrelation detection technique may include steps of: calculating conditional probabilities by, among other things, normalizing crosscoincidence histograms calculated from time-course data of activities of the neurons representing a train of action potentials of the neurons representing a train of action potentials of the neurons, and comparing trains of symbols representing time-course states of the activities of the neurons; distinguishing an inhibitory connectivity form an excitatory connectivity by comparing the conditional probabilities to each other; and quantitatively estimating the magnitude of crossrelation among the time-course data. The interneuron connection-structure estimation technique may include steps of: computing conditional probabilities by normalizing cross-coincidence histograms calculated from time-course data of activities of the neurons representing a train of action potentials of the neurons; computing conditional mutual information and three-point mutual information from the computed conditional probabilities; and inferring a connection structure among the neurons.

摘要翻译： 本发明提供一种中间神经元相关识别技术和中间神经元连接结构估计技术，用于通过获得时间线数据之间的相互关系来推断连接结构和构建神经网络模型所需的多个神经元之间的连接性的强度 的神经元。 中间神经元相关检测技术可以包括以下步骤：通过以下方法来计算条件概率：除了别的以外，归一化从表示代表一系列动作电位的神经元的动作电位的神经元的活动的时间过程数据计算的交叉整数直方图 并且比较表示神经元的活动的时间过程状态的符号列; 通过将条件概率相互比较来区分抑制连通性形成兴奋性连通性; 并定量估计时间序列数据之间的相关性的大小。 中间神经元连接结构估计技术可以包括以下步骤：通过归一化由表示神经元的动作电位列的神经元的活动的时间过程数据计算的交叉重合直方图来计算条件概率; 从计算的条件概率计算条件互信息和三点互信息; 并推断神经元之间的连接结构。

公开(公告)号：US5376016A

公开(公告)日：1994-12-27

申请号：US88539

申请日：1993-07-09

申请人： Shigemitsu Inaba ,  Satoshi Yamada

发明人： Shigemitsu Inaba ,  Satoshi Yamada

IPC分类号： H01R13/639 ,  H01R13/621 ,  H01R13/627 ,  H01R43/26

CPC分类号： H01R13/6273 ,  H01R13/6215 ,  H01R43/26

摘要： A connector which includes a male connector housing (1), a female connector housing (2), and a rotary shaft (3) for camming the male connector housing (1) into engagement with the female connector housing. The male connector housing 1 includes flexible arms (6) having engagement claws (8) for alternatively engaging holes (19) and (20) provided in the female connector housing so as to retain the connector housings in a provisionally engaged position or a completely engaged position. The flexible arms also include a constrictive portion (7) for flexing the arms outwardly when the shaft is inserted into the connector housings. As a result, the engagement claws (8) are disengaged from the provisional engagement holes (19) so that the connector housings can be moved to the completely engaged position. After the connector housings have been moved to the completely engaged position as a result of rotation of the shaft, the shaft can than be removed from the connector housings so that the claws (8) engage holes (20).

摘要翻译： 一种连接器，其包括阳连接器壳体（1），阴连接器壳体（2）和用于使阳连接器壳体（1）与阴连接器壳体接合的旋转轴（3）。 阳连接器壳体1包括具有接合爪（8）的柔性臂（6），用于交替地接合设置在阴连接器壳体中的孔（19）和（20），以便将连接器壳体保持在临时接合位置或完全接合 位置。 柔性臂还包括用于当轴插入连接器壳体时将臂向外弯曲的缩颈部分（7）。 结果，接合爪（8）与临时接合孔（19）脱离，使得连接器壳体能够移动到完全接合位置。 在连接器壳体由于轴的旋转已经移动到完全接合位置之后，轴可以从连接器壳体移除，使得爪（8）接合孔（20）。

公开(公告)号：US5354986A

公开(公告)日：1994-10-11

申请号：US974873

申请日：1992-11-12

申请人： Satoshi Yamada ,  Hirohisa Yamamoto ,  Shigeru Shiratake

发明人： Satoshi Yamada ,  Hirohisa Yamamoto ,  Shigeru Shiratake

IPC分类号： C23C14/48 ,  C23C14/54 ,  G21K1/14 ,  H01J37/02 ,  H01J37/317 ,  H01L21/265 ,  H01J37/30 ,  H05H3/00

CPC分类号： G21K1/14 ,  H01J37/023 ,  H01J37/3171 ,  H01J2237/0044 ,  H01J2237/30455

摘要： An ion implantation apparatus includes a charge neutralizer having a control circuit which controls the quantity of secondary electrons irradiating a semiconductor wafer. Electrons are generated in response to a direction of movement of a semiconductor wafer to neutralize positive charge on the semiconductor wafer. The apparatus can neutralize the positive charge homogeneously and prevent electrical breakdown of the semiconductor wafer.

摘要翻译： 离子注入装置包括具有控制电路的电荷中和器，该控制电路控制照射半导体晶片的二次电子的量。 响应于半导体晶片的移动方向产生电子以中和半导体晶片上的正电荷。 该装置可以均匀地中和正电荷并防止半导体晶片的电击穿。

公开(公告)号：US5304067A

公开(公告)日：1994-04-19

申请号：US928777

申请日：1992-08-13

申请人： Shigemitsu Inaba ,  Toru Nagano ,  Satoshi Yamada ,  Hiroki Kondo

发明人： Shigemitsu Inaba ,  Toru Nagano ,  Satoshi Yamada ,  Hiroki Kondo

IPC分类号： H01R13/648 ,  H01R4/64 ,  H01R9/18 ,  H01R13/52 ,  H01R13/658 ,  H01R

CPC分类号： H01R9/18 ,  H01R13/6582 ,  H01R13/6593 ,  H01R13/648 ,  H01R4/64

摘要： A shielded connector is provided which directly grounds harmful noise in the connector to the mounting body at the same time that the connector is mounted to the body. A metal shell is interposed between the insulating inner housing accommodating a terminal and the insulating outer housing accommodating the inner housing. The metal shell is provided with a metal clamp for grounding which projects outwardly from the outer housing to be directly fixed to a grounding body by a bolt.

摘要翻译： 提供了一种屏蔽连接器，其在连接器安装到身体的同时直接将连接器中的有害噪声接触到安装体。 金属壳插入在容纳端子的绝缘内壳体和容纳内壳体的绝缘外壳之间。 金属外壳设置有用于从外壳向外突出的用于接地的金属夹，以通过螺栓直接固定到接地体。

公开(公告)号：US5209016A

公开(公告)日：1993-05-11

申请号：US798563

申请日：1991-11-26

申请人： Satoshi Yamada

发明人： Satoshi Yamada

IPC分类号： B60R7/04 ,  B65D43/16 ,  E05C21/00 ,  E05D15/50

CPC分类号： E05D15/505 ,  B60R7/04 ,  E05Y2900/538 ,  Y10T16/528 ,  Y10T292/0901 ,  Y10T292/0907 ,  Y10T292/438

摘要： An apparatus for opening and closing a lid disposed rotatably on an opening of a box body selectively in two directions includes a pair of operating members independently movably supported one each at opposite ends of the lid, a spring member having a pair of rotary shafts disposed on an inner side of the lid so as to advance or retreat under the influence of resilient pressure of the spring member, two pairs of storage mouths formed in the edge of the opening of the box body at four corner portions thereof, two pairs of lock members pivotally supported inside the storage mouths for detachably supporting the rotary shafts above the storage mouths, and two pairs of rotary gear mechanisms attached to the lock members so that each pair of rotary gear mechanisms are interconnected to each other and the two pairs of rotary gear mechanisms are interlocked with each other. The rotary shafts are connected to the operating members so as to urge the operating members outwardly away from each other by virtue of the resilient pressure of the spring member. Each of the rotary shafts connected to the operating members is released from the lock members by a pressing operation of the corresponding operating member. The pressing operation of one of the operating members to open the lid in one direction causes one pair of lock members on the side being opened to be rotated and plunged into the corresponding pair of storage mouths due to the interlocking between the two pairs of rotary gear mechanisms.

摘要翻译： 用于打开和关闭可选择性地沿两个方向可旋转地设置在箱体的开口上的盖的装置包括一对可自由移动地支撑在盖的相对端部的操作构件，弹簧构件，其具有设置在盖上的一对旋转轴 盖子的内侧在弹簧构件的弹性压力的影响下前进或后退，两对储存口形成在盒体的开口的四个角部的边缘处，两对锁定构件 枢转地支撑在储存口内部，用于可拆卸地支撑在储存口上方的旋转轴，以及两对连接到锁定构件的旋转齿轮机构，使得每对旋转齿轮机构彼此互连，并且两对旋转齿轮机构 彼此互锁。 旋转轴连接到操作构件，以便借助于弹簧构件的弹性压力使操作构件向外远离彼此。 连接到操作构件的每个旋转轴通过相应的操作构件的按压操作而从锁定构件释放。 一个操作构件的按压操作在一个方向上打开盖子使得打开的一侧的一对锁定构件由于两对旋转齿轮之间的联锁而被旋转并且入口到相应的一对存储口中 机制

公开(公告)号：US5195272A

公开(公告)日：1993-03-23

申请号：US764192

申请日：1991-09-23

申请人： Satoshi Yamada

发明人： Satoshi Yamada

IPC分类号： A45C13/10 ,  B60R7/04 ,  E05C21/00 ,  E05D15/50

CPC分类号： B60R7/04 ,  A45C13/10 ,  E05B83/32 ,  E05D15/505 ,  E05Y2900/538 ,  E05Y2900/602 ,  Y10T16/528 ,  Y10T292/0901 ,  Y10T292/0907 ,  Y10T292/438

摘要： A switching device includes operating members independently movably supported at opposite sides of a lid, a spring having a pair of rotary shaft parts disposed on the inner side of the lid so as to advance or retreat under the influence of the resilient pressure of the spring, and lock members disposed on opposite sides of an opening of a box body so as to detachably fasten the rotary shaft parts thereto. The rotary shaft parts are connected to the operating members so as to urge the operating members outwardly away from each other by virtue of the resilient pressure of the spring and are removed from the lock members by depressing motion the operating members. Owing to the construction, the lid is ensured to produce an infallible shut state on the box body by bringing the rotary shaft parts into engagement with the lock members due to the resilient pressure of the spring. The lid can also be infallibly opened in either of two directions by selectively removing the rotary shaft parts from the lock members by depressing either of the operating members.

公开(公告)号：US4824834A

公开(公告)日：1989-04-25

申请号：US105581

申请日：1987-10-08

申请人： Setsuro Fujii ,  Hiroyuki Kawamura ,  Hiroshi Kiyokawa ,  Satoshi Yamada

发明人： Setsuro Fujii ,  Hiroyuki Kawamura ,  Hiroshi Kiyokawa ,  Satoshi Yamada

IPC分类号： A61K31/53 ,  A61P19/06 ,  A61P43/00 ,  C07D487/04

CPC分类号： C07D487/04 ,  Y02P20/582

摘要： Pyrazolotriazine compounds of the formula: ##STR1## wherein R.sup.1 is OH or alkanoyloxy; R.sup.2 is H, OH, or SH; R.sup.3 is (1) unsaturated N- or S-containing heterocyclic group optionally having 1-2 substituents of halogen, nitro or phenylthio, (2) naphthyl, (3) phenyl optionally having 1-3 substituents of (i) alkyl, (ii) phenyl, (iii) alkoxycarbonyl, (iv) cyano, (v) nitro, (vi) alkoxy, (vii) phenylalkoxy (viii) phenylthio-alkyl, (ix) phenoxy, (x) ##STR2## R is alkyl, halo-substituted alkyl, phenyl optionally having 1-3 substituents, or pyridyl, and l is 0, 1 or 2, (xi) halogen, (xii) phenylalkyl, (xiii) carboxy, (xiv) alkanoyl, (xv) benzoyl optionally having 1-3 substituents, (xvi) amino, (xvii) OH, (xviii) alkanoyloxy, (xix) ##STR3## or (xx) ##STR4## (A is alkylene), said compounds having a xanthine oxidase inhibitory activity and are useful for the prophylaxis and treatment of gout.

摘要翻译： 下式的吡唑并三嗪化合物：其中R1是OH或烷酰氧基; R2是H，OH或SH; R3是（1）任选具有1-2个卤素取代基的不饱和N-或S-杂环基，硝基或苯硫基，（2）萘基，（3）任选具有1-3个（i）烷基取代基的苯基，（ii） ）苯基，（iii）烷氧基羰基，（iv）氰基，（ⅴ）硝基，（vi）烷氧基，（i）苯基烷氧基（ii）苯硫基烷基，（ix）苯氧基，（Ⅹ） 取代的烷基，任选具有1-3个取代基的苯基或吡啶基，l是0,1或2，（xi）卤素，（xii）苯基烷基，（xiii）羧基，（xiv）烷酰基，（xv） 1-3取代基，（xvi）氨基，（xvii）OH，（xviii）烷酰氧基，（xix）或（xx）（A是亚烷基），所述化合物具有黄嘌呤氧化酶抑制活性， 用于预防和治疗痛风。

公开(公告)号：US4710695A

公开(公告)日：1987-12-01

申请号：US914040

申请日：1986-10-01

申请人： Satoshi Yamada ,  Kaoru Furukawa

发明人： Satoshi Yamada ,  Kaoru Furukawa

IPC分类号： H02M3/338 ,  H02J7/02 ,  H02J7/10 ,  H02M3/335

CPC分类号： H02M3/335 ,  H02J7/022

摘要： A transformer employed in a power supply circuit of a ringing choke converter type comprises two feedback windings which share the current to be supplied to the base of a switching transistor for blocking oscillation. By virtue of the provision of the two feedback windings, a speedup capacitor for delivering a trigger current to the switching transistor is allowed to have less capacity, while the amount of heat generation of a resistor for regulating the trigger current can be restrained. These advantageous features of the present invention produces the effect that the bulk and weight of the capacitor and the resistor can be reduced, which leads to curtailing of the cost of the components as well as enhancing of the reliability of the circuit. The effect is more appreciable when a higher output is required.

摘要翻译： 用于振铃电抗器转换器类型的电源电路中的变压器包括两个反馈绕组，它们共享用于阻断振荡的开关晶体管的基极的电流。 通过提供两个反馈绕组，允许用于将触发电流传送到开关晶体管的加速电容器具有较小的容量，而可以抑制用于调节触发电流的电阻器的发热量。 本发明的这些有利特征产生了电容器和电阻器的体积和重量可以减小的效果，这导致部件成本的削减以及电路的可靠性的提高。 当需要更高的产量时，效果更明显。

公开(公告)号：US09461289B2

公开(公告)日：2016-10-04

申请号：US13881869

申请日：2011-09-28

申请人： Youichi Matsuura ,  Yoshitaka Fukagai ,  Satoshi Yamada ,  Etsuo Ogami ,  Satoshi Okano ,  Tomoyuki Ichikawa

发明人： Youichi Matsuura ,  Yoshitaka Fukagai ,  Satoshi Yamada ,  Etsuo Ogami ,  Satoshi Okano ,  Tomoyuki Ichikawa

IPC分类号： H01M2/16 ,  H01M2/02 ,  H01M4/04 ,  H01M4/13 ,  H01M4/139 ,  H01M10/052 ,  H01M10/0566 ,  H01M10/058 ,  H01M4/66

CPC分类号： H01M2/0482 ,  H01M2/08 ,  H01M2/1653 ,  H01M4/0404 ,  H01M4/13 ,  H01M4/139 ,  H01M4/667 ,  H01M4/668 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0566 ,  H01M10/058 ,  Y02E60/122 ,  Y02P70/54 ,  Y10T29/49115

摘要： A secondary battery includes an outer housing and an electrode body including a positive electrode member, separator member and a negative electrode member stacked in this order wherein the positive electrode member and the negative electrode member are formed from a collector and an active material layer formed to cover one end on the collector, an insulating body in which an insulating material that does not exhibit adhesiveness at room temperature is adhered with an adhesive strength of 1 N/15 mm or greater onto the collector constituting the positive electrode member or the negative electrode member, and a peripheral edge of the positive electrode member or the negative electrode member has a cross-sectional surface including the collector and the insulating body.

摘要翻译： 二次电池包括外壳体和电极体，该电极体具有以下顺序堆叠的正极部件，隔膜部件和负极部件，其中正极部件和负极部件由集电体形成，活性物质层形成为 覆盖在集电体上的一端，绝缘体，其中在室温下不显示粘合性的绝缘材料以构成正电极部件或负极部件的集电体的形式粘合有1N / 15mm以上的粘合强度 并且正极部件或负极部件的周缘具有包括集电体和绝缘体的截面。