公开(公告)号：US07037684B2

公开(公告)日：2006-05-02

申请号：US10221677

申请日：2001-03-13

申请人： Shigezo Udaka ,  Seiji Sato ,  Toshiyuki Kudo ,  Shusaku Oka ,  Naohiko Higashikuni ,  Masaaki Kondo

发明人： Shigezo Udaka ,  Seiji Sato ,  Toshiyuki Kudo ,  Shusaku Oka ,  Naohiko Higashikuni ,  Masaaki Kondo

IPC分类号： C07H21/04 ,  C12P21/04 ,  C12N1/20 ,  C12N15/00 ,  A61K38/28

CPC分类号： C12P21/02 ,  C07K14/32 ,  C07K14/62 ,  C07K2319/02 ,  C07K2319/035 ,  C07K2319/75 ,  C12N9/90 ,  C12N15/625 ,  C12N15/75

摘要： The invention relates to a DNA that enables co-expression of a protein disulfide isomerase and a polypeptide having disulfide bonds. The invention further relates to a process of producing polypeptides using the DNA and a process of enhancing the efficiency of formation of correct disulfide bond in an expression system of a gene recombinant polypeptide having disulfide bonds.

摘要翻译： 本发明涉及能够共表达蛋白质二硫键异构酶和具有二硫键的多肽的DNA。 本发明还涉及使用该DNA产生多肽的方法和在具有二硫键的基因重组多肽的表达系统中提高正确二硫键形成的效率的方法。

公开(公告)号：US06935978B2

公开(公告)日：2005-08-30

申请号：US10685703

申请日：2003-10-16

申请人： Hisashi Hayakawa ,  Seiji Sato

发明人： Hisashi Hayakawa ,  Seiji Sato

IPC分类号： F16H7/08 ,  F16H7/22

CPC分类号： F16H7/0836 ,  F16H2007/0806 ,  F16H2007/0812 ,  F16H2007/0853 ,  F16H2007/0855 ,  F16H2007/0859 ,  F16H2007/0878

摘要： A chain tensioner is provided, in which the design conditions of a register ring are optimized in compliance with the required functions so as to improve the durability, the operational stability and the like of the chain tensioner. A register ring is formed of a steel material having a tensile strength of 1000 to 3500 N/mm2. At the same time, an overlapping allowance of the register ring with respect to engagement grooves of a plunger is set within the range of 30 to 50% of a wire diameter of the register ring. Furthermore, a bending stress generated in the register ring when the register ring is made to slide between the engagement grooves to increase its diameter is set within the range of 500 to 1700 N/mm2.

摘要翻译： 提供了一种链条张紧器，其中根据所需的功能优化对准环的设计条件，从而提高链条张紧器的耐用性，操作稳定性等。 记录环由拉伸强度为1000〜3500N / mm 2的钢材形成。 同时，相对于柱塞的接合槽的定位环的重叠余量设定在对准环的线径的30〜50％的范围内。 此外，当使定位环在接合槽之间滑动以增加其直径时在定位环中产生的弯曲应力设定在500至1700N / mm 2的范围内。

公开(公告)号：US06864862B2

公开(公告)日：2005-03-08

申请号：US10149264

申请日：2001-02-07

申请人： Seiji Sato ,  Hidehiko Sekizawa

发明人： Seiji Sato ,  Hidehiko Sekizawa

IPC分类号： G02F1/13 ,  G02B27/22 ,  G02B27/26 ,  G09F9/00 ,  H04N13/00 ,  H04N13/04 ,  G09G3/00

CPC分类号： G02B27/2214 ,  G02B27/26 ,  H04N13/305 ,  H04N13/307 ,  H04N13/31 ,  H04N13/32 ,  H04N13/324 ,  H04N13/351 ,  H04N13/38 ,  H04N13/398

摘要： A light source (60) is provided in the rear of display means (30), which has a light transmission type display and is made up of pixels (31) for left and right eyes and a first image separation mechanism (32) for the left and right eyes, with a lens unit (41) having a collecting power in a vertical direction and a second image separation mechanism (52) therebetween. The transmission light from the light source (60) spreads in the vertical direction as shown in the drawing. Such spread of the light occurs over the whole of a display surface. It is therefore possible to view the image on the display surface, when the viewer's head is located at any of positions 1 to 4. Accordingly, it becomes possible to make a degree of freedom in vertical (up-and-down) positional movement of the viewer's head.

摘要翻译： 在显示装置（30）的后部设置光源（60），其具有透光型显示器，并且由用于左眼和右眼的像素（31）和用于左眼和右眼的第一图像分离机构（32）构成， 左眼和右眼，具有在垂直方向上具有收集力的透镜单元（41）和在其间的第二图像分离机构（52）。 来自光源（60）的透射光如图所示沿垂直方向扩展。 光的这种扩散发生在整个显示表面上。 因此，当观察者的头部位于位置1至4中的任何一个位置时，可以在显示器表面上观看图像。因此，可以使垂直（上下）位置移动的自由度 观众的脑袋。

公开(公告)号：US06681050B1

公开(公告)日：2004-01-20

申请号：US09407881

申请日：1999-09-29

申请人： Takeshi Makiyama ,  Seiji Sato ,  Noritaka Koizumi ,  Tadashi Uchiumi

发明人： Takeshi Makiyama ,  Seiji Sato ,  Noritaka Koizumi ,  Tadashi Uchiumi

IPC分类号： G06K936

CPC分类号： H04N19/00 ,  H04N19/12 ,  H04N19/156 ,  H04N19/164 ,  H04N19/44 ,  H04N19/46 ,  H04N19/51 ,  H04N19/523 ,  H04N19/61 ,  H04N19/70 ,  H04N19/82 ,  H04N21/25858 ,  H04N21/2662 ,  H04N21/435 ,  H04N21/8193

摘要： A coding and decoding apparatus is constructed so that the coding side transmits coded data together with identifying information for identifying the device of decoding the coded data, and the decoding side is capable of storing a number of decoding schemes so as to perform decoding based on one of the previously stored schemes. The apparatus further has devices for storing the received tools and tool-correspondent information which numerically represents the capacities of the tools so that it can make a comparison between the decoding capacity and the processing capacities of the tools to determine the possibility of the operations of the received tools. Further, a set of the tools are hierarchized so that the coded data produced by the n-ranked tool can be decoded by the (n+1)-ranked tool. Alternatively, the tools are defined in a hierarchical manner so that the decoding tools installed in the decoding apparatus will be able to assure the minimum quality and the requested decoding process can be performed by the received decoding tool. Further, the identification code of the decoding scheme used can be transmitted as required so that the decoding scheme can be expanded by transmitting the differential information from the basic decoding scheme.

公开(公告)号：US06614475B1

公开(公告)日：2003-09-02

申请号：US09214737

申请日：1999-04-12

申请人： Satoshi Yamaga ,  Seiji Sato ,  Keiichi Ito

发明人： Satoshi Yamaga ,  Seiji Sato ,  Keiichi Ito

IPC分类号： H04N5202

CPC分类号： H04N5/3572 ,  H04N5/361

摘要： An average signal level of imaging signals obtained by a solid-state image pickup device of an image pickup unit 112 is detected by an average signal level detection circuit 116. Based on APL (average picture level) data specifying the average signal level APL as detected by this average signal level detection circuit 116, a system control micro-computer 117 refers to a table of an average signal level versus correction level finction specifying the correction level in the plural average signal levels previously stored in a memory 118 to read out flare correction data conforming to the APL data. A D/A-LPF circuit 119 converts the flare correction data by digital/analog (D/A) conversion to generate flare correction data, which are summed by adders 114R, 114G and 114B to imaging signal obtained by said solid-state image pickup device.

摘要翻译： 由平均信号电平检测电路116检测由摄像单元112的固态图像摄取装置获得的成像信号的平均信号电平。基于指定检测到的平均信号电平APL的APL（平均图像电平）数据 通过该平均信号电平检测电路116，系统控制微计算机117参考平均信号电平对校正电平精度的表，其指定先前存储在存储器118中的多个平均信号电平中的校正电平，以读出耀斑校正 数据符合APL数据。 AD / A-LPF电路119通过数字/模拟（D / A）转换来转换闪光校正数据，以产生闪光校正数据，其由加法器114R，114G和114B相加到由所述固态图像拾取装置获得的成像信号 。

公开(公告)号：US06506595B2

公开(公告)日：2003-01-14

申请号：US09280030

申请日：1999-03-26

申请人： Seiji Sato ,  Naohiko Higashikuni ,  Toshiyuki Kudo ,  Masaaki Kondo

发明人： Seiji Sato ,  Naohiko Higashikuni ,  Toshiyuki Kudo ,  Masaaki Kondo

IPC分类号： C12N1500

CPC分类号： C12N15/625 ,  C07K14/605 ,  C07K14/61 ,  C07K14/62 ,  C07K14/655 ,  C07K2319/034 ,  C07K2319/21 ,  C07K2319/50 ,  C07K2319/75

摘要： This invention relates to a DNA comprising a nucleotide sequence encoding a fusion protein, wherein the fusion protein comprises: a sequence of signal peptide for Bacillus cell wall protein (CWP); a tag sequence for separation and purification of the fusion protein; a linker sequence; a sequence for chemical or enzymatic cleavage; and an exogenous polypeptide sequence, the sequences being linked in order, the signal peptide, tag and linker being optional sequences; and wherein the nucleotide sequence encoding a fusion protein is ligated to 3′-end of a nucleic acid sequence comprising a Bacillus promoter region; to a vector comprising the DNA; to a bacterium belonging to the genus Bacillus comprising the vector; and to a process for preparation of a useful polypeptide by culture of the bacterium.

摘要翻译： 本发明涉及包含编码融合蛋白的核苷酸序列的DNA，其中融合蛋白包含：用于芽孢杆菌细胞壁蛋白（CWP）的信号肽序列; 用于分离和纯化融合蛋白的标签序列; 接头序列; 用于化学或酶切割的序列; 和外源多肽序列，序列依次连接，信号肽，标签和接头是任选的序列; 并且其中将编码融合蛋白的核苷酸序列连接到包含芽孢杆菌启动子区的核酸序列的3'-末端; 涉及包含该DNA的载体; 涉及属于包含载体的芽孢杆菌属的细菌; 以及通过细菌培养制备有用多肽的方法。

公开(公告)号：US06444703B1

公开(公告)日：2002-09-03

申请号：US09091588

申请日：1998-08-12

申请人： Osamu Kamoda ,  Toshiharu Yanagi ,  Eiji Tamaki ,  Seiji Sato ,  Jun-ichi Mizoguchi

发明人： Osamu Kamoda ,  Toshiharu Yanagi ,  Eiji Tamaki ,  Seiji Sato ,  Jun-ichi Mizoguchi

IPC分类号： A61K3124

CPC分类号： B82Y5/00 ,  A61K31/24 ,  A61K47/6951

摘要： The present invention relates to a pharmaceutical composition which is appropriate for eradication or extermination of Helicobacter pylori wherein [4-[4-(4-methylbenzyloxycarbonyl)phenyl[phenyl trans-4-guanidinomethylcyclohexanecarboxylate or an acid addition salt thereof are compounded and it also relates to a complex consisting them.

摘要翻译： 本发明涉及一种适用于根除或消灭幽门螺杆菌的药物组合物，其中[4- [4-（4-甲基苄氧基羰基）苯基] [反式-4-胍基甲基环己烷甲酸苯酯或其酸加成盐被复合并且也涉及 到一个复杂的组成他们。

公开(公告)号：US5853660A

公开(公告)日：1998-12-29

申请号：US542828

申请日：1995-10-13

申请人： Yasuo Murakami ,  Nobuaki Mitamura ,  Seiji Sato

发明人： Yasuo Murakami ,  Nobuaki Mitamura ,  Seiji Sato

IPC分类号： F16C33/62 ,  C21D1/18 ,  C21D1/32 ,  C21D1/78 ,  C21D9/40 ,  C22C38/00 ,  C22C38/18

CPC分类号： C22C38/18 ,  C21D1/78 ,  C21D9/40 ,  C21D1/18 ,  C21D1/32 ,  Y10S148/906

摘要： A bearing steel includes 0.70 to 0.93 wt % of C, 0.15 to 0.50 wt % of Si, 0.50 to 1.10 wt % of Mn and 0.3 to 0.65 wt % of Cr, with the balance being Fe and incidental impurities, and it has the ratio Cr/C specified to fall within 0.4 to 0.7. Because of these compositional features, the generation of macro carbides is prevented and the need to perform soaking at high temperature for a prolonged time is eliminated. Further, the bearing steel saves the materials cost and the overall cost of heat treatments in the manufacture of bearings and which yet is capable of satisfying the requirements of various characteristics of bearings, as well as a rolling bearing that employs the bearing steel.

摘要翻译： 轴承钢包括C：0.70〜0.93重量％，Si：0.15〜0.50重量％，Mn：0.50〜1.10重量％，Cr：0.3〜0.65重量％，余量：Fe和附带杂质， Cr / C规定为0.4〜0.7。 由于这些组成特征，防止了大量碳化物的产生，并且消除了在高温下长时间浸泡的需要。 此外，轴承钢节省了轴承制造中的材料成本和热处理的总体成本，并且能够满足轴承的各种特性的要求，以及采用轴承钢的滚动轴承。

公开(公告)号：US5836143A

公开(公告)日：1998-11-17

申请号：US892064

申请日：1997-07-14

申请人： Kiyomi Yoshida ,  Seiji Sato ,  Hiroyuki Matsuda

发明人： Kiyomi Yoshida ,  Seiji Sato ,  Hiroyuki Matsuda

IPC分类号： B65B9/06 ,  B65B9/073 ,  B65B61/24 ,  B65B65/02 ,  B65D35/00 ,  B65B9/20

CPC分类号： B65B61/24

摘要： A packaging machine comprises a device for forming incomplete containers by forming a web into a tube, filling contents into the tube, thereafter transporting the tube by a length corresponding to one container at a time, and sealing and cutting the tube transversely thereof every time the tube is transported; a container conveyor for receiving the incomplete containers from the device and transporting the containers; and a complete container forming device for making each incomplete container into a complete rectangular parallelepipedal container during transport on the conveyor. A drive device for use in the machine comprises a main shaft coupled to the incomplete container forming device so as to transmit power thereto, and a transmission shaft having one end connected to the main shaft by a main clutch and the other end coupled to a motor by a secondary clutch, the transmission shaft being coupled to the conveyor so as to transmit power.

摘要翻译： 一种包装机包括：通过将纤维网成形为管形成不完整的容器的装置，将内容物填充到管中，然后一次将管输送一个对应于一个容器的长度，并且每次将其横向密封和切割 管子运输; 容器输送机，用于从装置接收不完整的容器并运送容器; 以及一个完整的容器形成装置，用于在输送机上运输期间使每个不完整的容器成为一个完整的长方体容器。 一种用于机器的驱动装置，包括：一个联结到不完全容器成形装置的主轴，以便传递动力;一个传动轴，其一端通过一个主离合器与主轴连接;另一端连接一个电动机 通过二次离合器，传动轴联接到输送机以传递动力。

公开(公告)号：US5661011A

公开(公告)日：1997-08-26

申请号：US458393

申请日：1995-06-02

申请人： Toshiyuki Kudo ,  Yoshiaki Itagaki ,  Seiji Sato ,  Shizuyo Sutou ,  Toyoo Nakamura

发明人： Toshiyuki Kudo ,  Yoshiaki Itagaki ,  Seiji Sato ,  Shizuyo Sutou ,  Toyoo Nakamura

IPC分类号： C12N15/09 ,  C12Q1/68 ,  C12P19/34

CPC分类号： C12Q1/6879

摘要： The present invention provides PCR primers with which sexing of bovine embryos can be easily attained and provides a practical, rapid and reliable method for determining the sex of bovine embryos using these primers. The methods for determining the sex of the bovine embryos are characterized by discriminating PCR products which are obtained by amplifying specific DNA sequences by PCR with pairs of male-specific and gender-neutral primers. These primers are derived from DNAs which specifically hybridize to the bovine male genome and from DNAs which gender-neutrally hybridize to both bovine male and female genomes.

摘要翻译： 本发明提供可以容易地获得牛胚胎性别的PCR引物，并提供使用这些引物确定牛胚胎性别的实用，快速和可靠的方法。 用于确定牛胚胎性别的方法的特征在于区分通过用雄性特异性和性别中性引物的PCR扩增特异性DNA序列获得的PCR产物。 这些引物衍生自与牛雄性基因组特异性杂交的DNA，以及与牛雄性和雌性基因组性别中性杂交的DNA。