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公开(公告)号:US08414901B2
公开(公告)日:2013-04-09
申请号:US13358905
申请日:2012-01-26
CPC分类号: A61K39/0225 , A61K2039/552 , A61K2039/55566 , Y02A50/401
摘要: The present invention provides a vaccine for canine Lyme disease and methods of making and using the vaccine alone, or in combinations with other protective agents.
摘要翻译: 本发明提供了一种针对犬莱姆病的疫苗,以及单独制备和使用该疫苗或与其它保护剂组合的方法。
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公开(公告)号:US08137678B2
公开(公告)日:2012-03-20
申请号:US11933583
申请日:2007-11-01
CPC分类号: A61K39/0225 , A61K2039/552 , A61K2039/55566 , Y02A50/401
摘要: The present invention provides a vaccine for canine Lyme disease and methods of making and using the vaccine alone, or in combinations with other protective agents.
摘要翻译: 本发明提供了针对犬莱姆病的疫苗,以及单独制备和使用疫苗或与其它保护剂组合的方法。
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公开(公告)号:US07972604B2
公开(公告)日:2011-07-05
申请号:US12869813
申请日:2010-08-27
IPC分类号: A61K39/02
CPC分类号: A61K39/08 , A61K2039/522 , A61K2039/523 , C07K14/33
摘要: The present invention discloses attenuated Clostridium perfringens organisms that express a substantially nontoxic alpha-toxin. The expressed alpha-toxin is a deletion mutein that relative to the alpha-toxin of the mature alpha-toxin of Clostridium perfringens strain 13, is missing at least nine consecutive amino acid residues including His68. The present invention also discloses attenuated organisms that encode the muteins, as well as the use of such attenuated organisms as vaccines.
摘要翻译: 本发明公开了表达基本上无毒的α-毒素的减毒产气荚膜梭菌生物体。 表达的α-毒素是相对于产气荚膜梭菌菌株13的成熟α-毒素的α-毒素的缺失突变蛋白缺失至少九个连续的氨基酸残基,包括His68。 本发明还公开了编码突变蛋白的减毒生物,以及这些减毒生物体作为疫苗的用途。
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公开(公告)号:US07807456B2
公开(公告)日:2010-10-05
申请号:US12640645
申请日:2009-12-17
IPC分类号: C12N15/00
CPC分类号: A61K39/08 , A61K2039/522 , A61K2039/523 , C07K14/33
摘要: The present invention discloses attenuated Clostridium perfringens organisms that express a substantially nontoxic alpha-toxin. The expressed alpha-toxin is a deletion mutein that relative to the alpha-toxin of the mature alpha-toxin of Clostridium perfringens strain 13, is missing at least nine consecutive amino acid residues including His68. The present invention also discloses attenuated organisms that encode the muteins, as well as the use of such attenuated organisms as vaccines.
摘要翻译: 本发明公开了表达基本上无毒的α-毒素的减毒产气荚膜梭菌生物体。 表达的α-毒素是相对于产气荚膜梭菌菌株13的成熟α-毒素的α-毒素的缺失突变蛋白缺失至少九个连续的氨基酸残基,包括His68。 本发明还公开了编码突变蛋白的减毒生物,以及这些减毒生物体作为疫苗的用途。
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公开(公告)号:US20100166803A1
公开(公告)日:2010-07-01
申请号:US12616341
申请日:2009-11-11
申请人: Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
发明人: Steve Hewart Fitz-Coy , Gamini Saman Kumara Withanage , Alexandria Louise McGowan , Stephanie M. Cook
IPC分类号: A61K39/012 , C12Q1/68
CPC分类号: C12Q1/6893 , A61K39/012 , A61K2039/552 , C07K14/455 , Y02A50/489
摘要: The present invention discloses a vaccine that provides protection to turkeys from coccidiosis, and methods of making and using the vaccine alone, or in combinations with other protective agents. In addition, the present invention discloses PCR primer sets that are useful in identifying the species of Eimeria in a biological sample.
摘要翻译: 本发明公开了一种疫苗,其提供来自球虫病的火鸡的保护,以及单独制备和使用疫苗或与其它保护剂组合的方法。 此外,本发明公开了可用于鉴定生物样品中艾美球虫种类的PCR引物组。
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公开(公告)号:US07732187B2
公开(公告)日:2010-06-08
申请号:US11734454
申请日:2007-04-12
IPC分类号: C12N1/20
CPC分类号: A61K39/08 , A61K2039/522 , A61K2039/523 , C07K14/33
摘要: The present invention discloses attenuated Clostridium perfringens organisms that express a substantially nontoxic alpha-toxin. The expressed alpha-toxin is a deletion mutein that relative to the alpha-toxin of the mature alpha-toxin of Clostridium perfringens strain 13, is missing at least nine consecutive amino acid residues including His68. The present invention also discloses attenuated organisms that encode the muteins, as well as the use of such attenuated organisms as vaccines.
摘要翻译: 本发明公开了表达基本上无毒的α-毒素的减毒产气荚膜梭菌生物体。 表达的α-毒素是相对于产气荚膜梭菌菌株13的成熟α-毒素的α-毒素的缺失突变蛋白缺失至少九个连续的氨基酸残基,包括His68。 本发明还公开了编码突变蛋白的减毒生物,以及这些减毒生物体作为疫苗的用途。
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公开(公告)号:US20100015182A1
公开(公告)日:2010-01-21
申请号:US12472805
申请日:2009-05-27
IPC分类号: A61K39/012 , A61K39/002 , A61P33/02
CPC分类号: A61K39/012 , A61K2039/52 , A61K2039/522 , A61K2039/552 , Y02A50/489
摘要: The present invention discloses a vaccine that provides protection from coccidiosis, and methods of making and using the vaccine alone, or in combination with other protective agents.
摘要翻译: 本发明公开了提供针对球虫病的保护的疫苗,以及单独制备和使用疫苗或与其它保护剂组合的方法。
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公开(公告)号:US5750514A
公开(公告)日:1998-05-12
申请号:US439419
申请日:1995-05-11
申请人: Jeffery A. Meyer
发明人: Jeffery A. Meyer
IPC分类号: A01K13/00 , A01M29/00 , A01N25/00 , A01N25/02 , A01N53/00 , A61K9/00 , A61K31/66 , A61K31/675 , A61P17/00 , A61P43/00 , A01N65/00
CPC分类号: A61K9/0017 , A01N25/02 , Y10S514/974 , Y10T428/31511
摘要: An improved method for controlling infestations of flies on an animal wherein a solution of an ectoparasiticide is applied to the skin or coat of the animal comprises increasing the concentration of the ectoparasiticide to about 3% to about 90% of the composition and proportionately reducing the volume of the solution administered to the animal such that the animal receives the same amount of the ectoparasiticide as it would have received prior to the concentration of the solution.
摘要翻译: 用于控制动物感染动物的改进方法,其中将外寄生虫杀螨剂的溶液施用于动物的皮肤或外皮包括将外用寄生虫抗病毒剂的浓度增加至组合物的约3%至约90%,并相应地减小体积 施用于动物的溶液,使得动物接受与溶液浓缩之前接收的相同量的杀螨剂。
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公开(公告)号:US20240358816A1
公开(公告)日:2024-10-31
申请号:US18684529
申请日:2022-06-29
发明人: Erwin Van Den Born , Ian Jones
IPC分类号: A61K39/135 , A61K39/00 , A61P37/04 , C07K14/005 , C12N15/86
CPC分类号: A61K39/135 , A61P37/04 , C07K14/005 , C12N15/86 , A61K2039/5258 , C12N2710/14044 , C12N2770/32122 , C12N2770/32123 , C12N2770/32134 , C12N2770/32152 , C12N2770/32171
摘要: The present invention provides a recombinant foot and mouth disease virus (FMDV) capsid precursor protein comprising a modified VP1 protein and optionally further comprising a modified VP4 protein. The invention further relates to an isolated nucleic acid molecule and an expression vector comprising the nucleic acid molecule for recombinant expression of the modified capsid precursor protein. In further aspects, the invention relates to a virus-like particle (VLP) obtained from the modified capsid precursor protein and a vaccine for use in the protection of a subject against an infection with FMDV produced from the VLP.
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90.
公开(公告)号:US12128032B2
公开(公告)日:2024-10-29
申请号:US17653950
申请日:2022-03-08
申请人: Intervet Inc.
IPC分类号: A01N43/80 , A01N43/90 , A61K9/00 , A61K9/08 , A61K31/42 , A61K31/422 , A61K31/437 , A61K47/10 , A61K47/26
CPC分类号: A61K31/42 , A01N43/80 , A01N43/90 , A61K9/0053 , A61K9/08 , A61K31/422 , A61K31/437 , A61K47/10 , A61K47/26
摘要: The present invention relates to methods of treating or preventing arthropod infestations of poultry animals and methods of controlling arthropod infestations in poultry animal's environment by administering an isoxazoline compound of formula (I)
via drinking water.
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