公开(公告)号：US20230260913A1

公开(公告)日：2023-08-17

申请号：US18003819

申请日：2021-07-08

Applicant: ROHM CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Masayuki FUJITA ,  Daniel Jonathan HEADLAND ,  Tadao NAGATSUMA ,  Yosuke NISHIDA

IPC: H01L23/538 ,  H01L21/768 ,  H01L29/66 ,  H01P3/16 ,  H04B10/572

CPC classification number: H01L23/538 ,  H01L21/76802 ,  H01L29/66219 ,  H01P3/16 ,  H04B10/572

Abstract: A terahertz module includes: a terahertz chip which includes an active device which emits a terahertz wave; and a dielectric substrate coupled to the terahertz chip. The terahertz chip includes a semiconductor substrate. The active device is disposed on an upper surface of the semiconductor substrate. A cutout is formed in a portion of a first side surface, among a plurality of side surfaces of the dielectric substrate, the cutout extending from an upper side of the first side surface to a lower side of the first side surface. The terahertz chip is fit into the cutout in such a direction that the upper surface of the semiconductor substrate is parallel to the first side surface and the semiconductor substrate is arranged in a bottom side of the cutout.

公开(公告)号：US20230243835A1

公开(公告)日：2023-08-03

申请号：US18002344

申请日：2021-06-22

Applicant: MITSUI CHEMICALS, INC. ,  OSAKA UNIVERSITY ,  UNIVERSITY OF MIYAZAKI

Inventor： Komako ISHIKAWA ,  Koh AMANO ,  Toshifumi TAKAO ,  Nobuaki OKUMURA ,  Toshiki TAKEI ,  Masamitsu NAKAZATO ,  Hironobu TSUBOUCHI

IPC: G01N33/574 ,  G01N33/70

CPC classification number: G01N33/57449 ,  G01N33/70 ,  G01N2800/7028

Abstract: An adenocarcinoma detection method based on a protein fragment of WFDC2 protein in a sample originating from a subject, the method comprising determining a presence of adenocarcinoma by comparing a first determination value and a threshold value set in advance, the first determination value being a value derived by dividing a first fragment quantity, which is a quantity of a protein fragment having an amino acid sequence of SEQ ID NO: 1 in the sample as determined by an ELISA method, by a reference quantity defined by a total quantity of WFDC2 protein or a creatinine concentration in the sample as determined by an ELISA method.

公开(公告)号：US11707516B2

公开(公告)日：2023-07-25

申请号：US16336735

申请日：2017-09-26

Applicant: Osaka University

Inventor： Takeshi Kobayashi ,  Yuta Kanai

IPC: A61K39/15 ,  A61P31/14 ,  C07K14/14 ,  C12N15/86 ,  C12N15/09

CPC classification number: A61K39/15 ,  A61P31/14 ,  C07K14/14 ,  C12N15/09 ,  C12N15/86

Abstract: Provided is a method for producing an artificial recombinant virus of the family Reoviridae, the method comprising the steps of:

(1) introducing a FAST protein expression vector and/or a capping enzyme expression vector into host cells;
(2) introducing a vector containing expression cassettes for individual RNA genome segments of a virus or introducing a set of single-stranded RNA transcripts from the expression cassettes into host cells; and
(3) culturing the host cells.


The method of the present invention allows more efficient production of an artificial recombinant virus of the family Reoviridae as compared with conventional methods and allows artificial recombinant rotavirus production without using a helper virus.

公开(公告)号：US20230210805A1

公开(公告)日：2023-07-06

申请号：US17926301

申请日：2021-03-05

Applicant: OSAKA UNIVERSITY

Inventor： Ken-ichi HIRANO

IPC: A61K31/225 ,  A61P9/10

CPC classification number: A61K31/225 ,  A61P9/10

Abstract: The present invention provides an agent for inducing regression of triglyceride (TG) deposit atherosclerosis, which agent comprises tricaprin/trisdecanoin as an active ingredient, an agent for improving blood flow in a patient with TG deposit atherosclerosis, which agent comprises tricaprin/trisdecanoin as an active ingredient, and a pharmaceutical or food or drink product comprising the agent for inducing regression of TG deposit atherosclerosis or the agent for improving blood flow.

公开(公告)号：US20230210441A1

公开(公告)日：2023-07-06

申请号：US17928855

申请日：2020-06-01

Applicant: NEC CORPORATION ,  OSAKA UNIVERSITY

Inventor： Masataka KIKUCHI ,  Yasusi MATSUMURA ,  Kaori KOBAYASHI ,  Kenichi KAMIJO ,  Yasuto FUSHIMI

IPC: A61B5/00

CPC classification number: A61B5/4088 ,  A61B5/4064 ,  A61B5/743

Abstract: A brain image analysis apparatus (2000) acquires input data (40) including a structural brain image (42) and a functional brain image (44) for a subject (10). The brain image analysis apparatus (2000) obtains analysis data (20) by inputting the input data (40) into an analysis model (2020). The analysis model (2020) has been trained in advance so as to output the analysis data (20) representing information about brain dysfunction in response to an input of the input data (40). The brain image analysis apparatus (2000) outputs, based on the analysis data (20), output data (30) representing information about the brain dysfunction of the subject (10).

公开(公告)号：US20230203131A1

公开(公告)日：2023-06-29

申请号：US17923323

申请日：2021-05-07

Applicant: OSAKA UNIVERSITY ,  MATRIXOME, INC.

Inventor： Kiyotoshi SEKIGUCHI ,  Mamoru TAKIZAWA ,  Yukimasa TANIGUCHI

IPC: C07K14/75 ,  C07K14/78 ,  C12N5/00

CPC classification number: C07K14/75 ,  C07K14/78 ,  C12N5/0068 ,  C12N5/0062 ,  C07K2319/00 ,  C12N2513/00

Abstract: The present invention provides a gel formed of fibrin and a molecule generated by thrombin treatment of a chimeric protein that comprises a fibrinogen fragment capable of binding to fibrinogen upon thrombin treatment and a laminin fragment having integrin-binding activity, and optionally further comprises a protein having growth factor-binding activity. The gel of the present invention is suitable as a gel substrate that has properties of the basement membrane and can be used in medical applications.

公开(公告)号：US20230202909A1

公开(公告)日：2023-06-29

申请号：US18067996

申请日：2022-12-19

Applicant: OSAKA UNIVERSITY ,  GC Corporation

Inventor： Satoshi IMAZATO ,  Haruaki KITAGAWA ,  Ayaka AKIYAMA ,  Tomoki KONO ,  Katsuhito KATO

IPC: C03C4/00 ,  C03C3/062 ,  C03C12/00

CPC classification number: C03C4/0035 ,  C03C3/062 ,  C03C4/0021 ,  C03C12/00 ,  C03C2201/12 ,  C03C2201/28 ,  C03C2201/40 ,  C03C2203/10

Abstract: A glass powder composite includes a first glass powder, and a second glass powder having a different solubility from that of the first glass powder depending on pH, wherein both the first glass powder and the second glass powder have ion sustained-release properties.

公开(公告)号：US20230194472A1

公开(公告)日：2023-06-22

申请号：US17605917

申请日：2020-04-24

Applicant: Osaka University

Inventor： Masateru Taniguchi ,  Hideshi Ishii ,  Takahito Ohshiro ,  Masamitsu Konno

IPC: G01N27/62 ,  C12Q1/6886

CPC classification number: G01N27/62 ,  C12Q1/6886

Abstract: The present disclosure provides a method for analyzing a microRNA using a tunneling current. The present disclosure provides a method for identifying the base sequence and/or modification state of a microRNA using a tunneling current, and a system and a program to be used in the method. Furthermore, the present disclosure provides a method for analyzing the conditions of a subject, said method comprising determining the base sequence and/or modification state of a microRNA using a tunneling current. For example, methylation modification can be analyzed thereby.

公开(公告)号：US20230173212A1

公开(公告)日：2023-06-08

申请号：US18070991

申请日：2022-11-29

Applicant: OSAKA UNIVERSITY ,  NIHON KOHDEN CORPORATION

Inventor： Takeshi YOSHIDA ,  Shigeo WADA ,  Naoki TAKEISHI ,  Satoshi YASUMURA ,  Isao MATSUBARA

IPC: A61M16/08 ,  A61M16/04

CPC classification number: A61M16/0816 ,  A61M16/0463

Abstract: A tracheal connector is connected to a respiratory gas generator and a tracheal tube. The tracheal connector includes a tracheal connector body connected to the tracheal tube, a connector tube connected to the tracheal connector body and the respiratory gas generator, and a restriction mechanism configured to narrow a respiratory gas flow path configured to allow the respiratory gas to flow therein. The tracheal connector body includes a tracheal port connected to the tracheal tube, an exhaust port facing the tracheal port and configured to discharge at least expired air of the subject, and a respiratory port connected to the connector tube. The restriction mechanism is provided on the respiratory gas flow path between the respiratory port and the tracheal port.

公开(公告)号：US20230167292A1

公开(公告)日：2023-06-01

申请号：US17988988

申请日：2022-11-17

Applicant: OSAKA UNIVERSITY ,  KABUSHIKI KAISHA TOSHIBA

Inventor： Yuji OHKUBO ,  Kazuya YAMAMURA ,  Erika MIYAKE ,  Izuru KOMATSU

IPC: C08L27/18 ,  B32B27/08 ,  B32B27/28 ,  B32B27/20 ,  B32B27/32 ,  B32B33/00

CPC classification number: C08L27/18 ,  B32B27/08 ,  B32B27/283 ,  B32B27/20 ,  B32B27/322 ,  B32B33/00 ,  B32B2264/1021 ,  B32B2307/70 ,  B32B2310/14 ,  B32B2250/02 ,  B32B2250/24 ,  B32B2305/30 ,  B32B2383/00 ,  B32B2327/18

Abstract: Provided is a laminated body that has high adhesiveness between a resin body containing a fluorine-based resin and a silicone gel and that can be attached to and detached from an adherend for use. A laminated body comprising: a resin body; and a gel body, wherein the resin body comprises a fluorine-based resin, and the gel body comprises a silicone gel and lipophilic silica particles.