公开(公告)号：US5409457A

公开(公告)日：1995-04-25

申请号：US171004

申请日：1993-12-21

申请人： Manuel del Cerro ,  Eliot Lazar

发明人： Manuel del Cerro ,  Eliot Lazar

IPC分类号： A61F2/16 ,  A61F9/007 ,  A61M5/158 ,  A61M31/00

CPC分类号： A61F9/00736 ,  A61M2025/0042 ,  A61M2210/0612

摘要： An intraretinal delivery and withdrawal instrument which has (a) a curved, distal frame for insertion into an orbit, which insertion is effected (i) inferior to the supraorbital ridge, (ii) superior to the eye, and (iii) in a caudal direction so as to reach the retina; (b) a tip for penetration into the subretinal region of the eye connected to the frame; and (c) an adjustable collar connected to the tip which collar is capable of being positioned so that the collar regulates the depth of tip penetration into the subretinal region including methods for uses thereof.

摘要翻译： 具有（a）用于插入轨道的弯曲的远端框架的内侧输送和取出器械，其插入（i）不如眶上脊，（ii）优于眼睛，和（iii）在尾部 方向到达视网膜; （b）用于穿透连接到框架的眼睛的视网膜下区域的尖端; 和（c）连接到所述尖端的可调节环，所述套环能够被定位，使得所述套环调节尖端穿入所述视网膜下区域的深度，包括其使用方法。

公开(公告)号：US5374940A

公开(公告)日：1994-12-20

申请号：US710221

申请日：1991-06-04

申请人： Mark A. Corio

发明人： Mark A. Corio

IPC分类号： G06F3/14 ,  H05K1/18 ,  G09G5/00

CPC分类号： G06F3/1438 ,  H05K1/189

摘要： Multiple video boards of the general purpose type (e.g. EGA or VGA boards) and their associated monitors are operated by a single computer of the personal computer type, without modification of the computer hardware and while the video boards reside in their usual expansion slots which are provided by connectors on the mother board of the personal computer by a system which utilizes a flexible printed circuit board containing circuits which allows the processor (CPU) of the computer to present address and data signals which operate circuitry on the flexible boards to selectively enable or inhibit the communication of control signals (on the I/O and memory read and write control lines) to the video boards thereby enabling them to generate graphical images for their associated monitors. The signals on the address control and data lines are tapped and relayed either directly or after processing to the associated video board thereby enabling multiple video boards of the same or different types to be used concurrently by appropriate programming of the computer without the need to interchange hardware to switch between displays thereby reducing the inconvenience and potential hardware damage necessarily incident to such a hardware interchange procedure.

摘要翻译： 通用型（例如EGA或VGA板）和其相关监视器的多个视频板由个人计算机类型的单个计算机操作，而不修改计算机硬件，而视频板驻留在其通常的扩展槽 由个人计算机母板上的连接器提供，该系统利用包含电路的柔性印刷电路板，该电路允许计算机的处理器（CPU）呈现在柔性板上操作电路的地址和数据信号，以选择性地启用或 禁止控制信号（在I / O和存储器读写控制线上）与视频板的通信，从而使它们能够为其相关监视器生成图形图像。 地址控制和数据线上的信号可以直接地或在处理之后被中继到相关联的视频板，从而使得能够通过对计算机的适当编程并行地使用相同或不同类型的多个视频板，而不需要交换硬件 在显示器之间进行切换，从而减少必然事件对这种硬件交换过程的不便和潜在的硬件损坏。

公开(公告)号：US5339062A

公开(公告)日：1994-08-16

申请号：US88936

申请日：1993-07-08

申请人： William R. Donaldson ,  Deepnarayan Gupta ,  Alan M. Kadin

发明人： William R. Donaldson ,  Deepnarayan Gupta ,  Alan M. Kadin

IPC分类号： H01F6/00 ,  H01L39/10 ,  H03K3/38 ,  H03K3/53 ,  H01F1/00 ,  H01F36/00

CPC分类号： H03K3/53 ,  H01F6/005 ,  H01F6/006 ,  H01L39/10 ,  H03K3/38 ,  Y10S336/01 ,  Y10S505/705

摘要： Electrical energy is transferred or switched by selectively holding off the coupling of a magnetic field to a secondary inductive element (a coil) through a path which contains a high temperature superconductive element (HTS) which is capable of holding off the field when in its superconductive state notwithstanding that it is a high energy magnetic field. The HTS operates to hold off the magnetic field in accordance with the flux exclusion effect. When the HTS element is driven normal by heating with a laser pulse, the flux passes through the element and couples the field to the secondary, which may be connected to a load. A primary coil of superconducting material around the secondary coil can provide superconducting magnetic energy storage. The primary field is held off by HTS elements in the flux path to opposite ends of the secondary coil. These elements may be driven normal by laser pulses to transfer the stored magnetic energy to a load. A plurality of secondary coils, each with associated HTS elements, may be selectively coupled to the load as programmed inductive elements (PIE).

摘要翻译： 通过选择性地将磁场与次级感应元件（线圈）的耦合通过包含高温超导元件（HTS）的路径来转移或切换电能，该高温超导元件（HTS）能够在其超导 尽管它是高能磁场。 HTS根据磁通排除效应来操作来阻止磁场。 当通过用激光脉冲加热将HTS元件驱动为正常时，磁通通过元件并将场耦合到次级，其可以连接到负载。 次级线圈周围的超导材料的初级线圈可以提供超导磁能存储。 初级场被HTS元件保持在通过二次线圈的相对端的通路中。 这些元件可以通过激光脉冲驱动正常，以将存储的磁能转移到负载。 具有相关联的HTS元件的多个次级线圈可以被编程的感应元件（PIE）选择性地耦合到负载。

公开(公告)号：US5078513A

公开(公告)日：1992-01-07

申请号：US610778

申请日：1990-11-08

申请人： Kevin Spaulding ,  G. Michael Morris

发明人： Kevin Spaulding ,  G. Michael Morris

IPC分类号： G02B6/124

CPC分类号： G02B6/1245

摘要： A lens in a waveguide of an integrated optical circuit is achromatized (corrected for chromatic dispersion which varies the focal length of the lens with wavelength) by forming the lens as a hybrid mode-index/diffractive doublet. The chromatic dispersion of the diffractive element cancels the dispersion of the refractive element (the mode-index lens) such that the derivative of the focal length goes to zero at the design wavelength, and significantly reduces chromatic dispersion over a substantial wavelength range. For example, a 10 mm focal length, F/5 hybrid mode-index/diffractive lens may be provided with a useable wavelength range of approximately 80 mm for typical waveguide materials.

摘要翻译： 通过将透镜形成为混合模式折射/衍射双峰，集成光电路的波导中的透镜被消色差（校正为通过波长改变透镜的焦距的色散）。 衍射元件的色散抵消折射元件（模式折射率透镜）的色散，使得焦距的导数在设计波长处变为零，并且在相当大的波长范围内显着地减小色散。 例如，对于典型的波导材料，可以为10mm焦距F / 5混合模式折射率/衍射透镜提供大约80mm的可用波长范围。

公开(公告)号：US5048029A

公开(公告)日：1991-09-10

申请号：US557273

申请日：1990-07-24

申请人： Stanley Skupsky ,  Terrance J. Kessler ,  Robert W. Short ,  Stephen Craxton ,  Samuel A. Letzring ,  John Soures

发明人： Stanley Skupsky ,  Terrance J. Kessler ,  Robert W. Short ,  Stephen Craxton ,  Samuel A. Letzring ,  John Soures

IPC分类号： G02F1/37 ,  G21K1/06 ,  H01S3/00 ,  H01S3/23

CPC分类号： H01S3/0057 ,  G02F1/37 ,  G21K1/06 ,  H01S3/2308 ,  G21K2201/062

摘要： In an SSD (smoothing by spectral dispersion) system which reduces the time-averaged spatial variations in intensity of the laser light to provide uniform illumination of a laser fusion target, an electro-optic phase modulator through which a laser beam passes produces a broadband output beam by imposing a frequency modulated bandwidth on the laser beam. A grating provides spatial and angular spectral dispersion of the beam. Due to the phase modulation, the frequencies ("colors") cycle across the beam. The dispersed beam may be amplified and frequency converted (e.g., tripled) in a plurality of beam lines. A distributed phase plate (DPP) in each line is irradiated by the spectrally dispersed beam and the beam is focused on the target where a smooth (uniform intensity) pattern is produced. The color cycling enhances smoothing and the use of a frequency modulated laser pulse prevents the formation of high intensity spikes which could damage the laser medium in the power amplifiers.

摘要翻译： 在减少激光强度的时间平均空间变化以提供激光融合目标的均匀照明的SSD（通过光谱色散平滑）系统中，激光束通过的电光相位调制器产生宽带输出 通过在激光束上施加调频带宽。 光栅提供光束的空间和角度光谱色散。 由于相位调制，频率（“颜色”）在横梁上循环。 分散的光束可以被放大并在多个光束线中进行频率转换（例如，三倍）。 每行中的分布相位板（DPP）被光谱分散光束照射，光束聚焦在产生光滑（均匀强度）图案的目标上。 颜色循环增强了平滑，并且使用调频激光脉冲防止形成高强度尖峰，这可能损坏功率放大器中的激光介质。

公开(公告)号：US5013133A

公开(公告)日：1991-05-07

申请号：US372735

申请日：1989-06-28

申请人： Dale A. Buralli ,  G. Michael Morris

发明人： Dale A. Buralli ,  G. Michael Morris

IPC分类号： G02B3/00 ,  G02B3/08 ,  G02B5/18 ,  G02B5/32 ,  G02B27/00 ,  G02B27/42 ,  G02B27/44

CPC分类号： G02B27/4216 ,  G02B27/0025 ,  G02B27/0037 ,  G02B3/00 ,  G02B5/1876 ,  Y10S359/90

摘要： A diffractive imaging lens, has a diffractive optical element and an aperture stop remote from the lens in the direction of the object to be imaged which corrects the lens for coma, astigmatism, and field curvature and which can be corrected for spherical aberration by using a phase corrector in the aperture of the stop. The lens system may be provided in anamorphic configuration.

公开(公告)号：US4997454A

公开(公告)日：1991-03-05

申请号：US343761

申请日：1989-04-26

申请人： Michael R. Violante ,  Harry W. Fischer

发明人： Michael R. Violante ,  Harry W. Fischer

IPC分类号： A61K9/14 ,  A61K9/16 ,  A61K49/04

CPC分类号： A61K9/14 ,  A61K49/0476 ,  A61K9/1688 ,  Y10S514/951 ,  Y10S514/965

摘要： The invention involves a method for making uniformly sized particles from solid compounds. First, a suitable solid compound is dissolved in a suitable solvent. Then, a precipitating liquid is infused, precipitating non-aggregated particles with substantially uniform mean diameter. The particles are then separated from the solvent. Depending on the solid compound and the desired particle size, the parameters of temperature, ratio of non-solvent to solvent, infusion rate, stir rate, and volume can be varied according to the invention. The precipitating liquid may be aqueous or non-aqueous, depending upon the relative solubility of the compound and the desired suspending vehicle.

公开(公告)号：US4896119A

公开(公告)日：1990-01-23

申请号：US618274

申请日：1984-06-07

申请人： Steven L. Williamson ,  Girard Mourou ,  Irl N. Duling, III ,  Philippe Bado ,  Carl H. Petras

发明人： Steven L. Williamson ,  Girard Mourou ,  Irl N. Duling, III ,  Philippe Bado ,  Carl H. Petras

IPC分类号： H01S3/23

CPC分类号： H01S3/235 ,  H01S3/0092 ,  H01S3/08054 ,  H01S3/107

摘要： A CW pumped regenerative laser amplifier system capable of producing amplified laser pulses of variable repetition rate (e.g., 10 Hz to 10 kHz) with high energy stability. The regenerative amplifier is seeded by pulses injected into the optical cavity of the amplifier from a CW pumped modelocked laser.

摘要翻译： CW泵浦再生激光放大器系统能够产生具有高能量稳定性的可变重复频率（例如10Hz至10kHz）的放大激光脉冲。 再生放大器通过从CW泵浦锁模激光器注入到放大器的光腔中的脉冲接种。

公开(公告)号：US4801541A

公开(公告)日：1989-01-31

申请号：US58688

申请日：1987-06-03

申请人： Yuko Yoneda ,  Frank E. Young

发明人： Yuko Yoneda ,  Frank E. Young

IPC分类号： C12N9/28 ,  C12N15/00 ,  C12N1/20 ,  C12R1/125

CPC分类号： C12N9/2417 ,  C12N15/00 ,  Y10S435/839

摘要： A method is described for increasing the yield of a product from a microorganism containing a regulatory gene, by altering the microorganism. The method involves introducing into the microorganism at least one structural gene for the product by lysogenizing the microorganism with a recombinant bacteriophage containing the structural gene.

摘要翻译： 描述了通过改变微生物从含有调节基因的微生物中提高产物产量的方法。 该方法包括通过用含有结构基因的重组噬菌体溶解微生物来向微生物引入至少一种产物结构基因。

公开(公告)号：US4761283A

公开(公告)日：1988-08-02

申请号：US845731

申请日：1986-03-28

申请人： Porter W. Anderson

发明人： Porter W. Anderson

IPC分类号： A61K39/102 ,  A61K39/385 ,  A61K39/02 ,  A61K39/09 ,  C07K15/04

CPC分类号： A61K39/385 ,  A61K39/092 ,  A61K39/102 ,  A61K2039/6037 ,  Y10S424/831 ,  Y10S424/832

摘要： An immunogenic conjugate which is the reductive amination product of an immunogenic capsular polymer fragment having a reducing end and derived from a bacterial capsular polymer of a bacterial pathogen, and a bacterial toxin or toxoid. The invention also relates to methods for the preparation of the conjugates, a vaccine containing the conjugates which elicits effective levels of anti-capsular polymer antibodies in humans. Also disclosed are methods for inducing active immunization against systemic infection in young mammals caused by bacterial pathogens comprising the administration of an immunogenic amount of the above-described conjugate.

摘要翻译： 免疫原性缀合物，其是具有还原末端并衍生自细菌病原体的细菌荚膜聚合物和细菌毒素或类毒素的免疫原性荚膜聚合物片段的还原性胺化产物。 本发明还涉及制备缀合物的方法，含有缀合物的疫苗，其引发人体中有效水平的抗荚膜聚合物抗体。 还公开了诱导由包含施用免疫原性量的上述缀合物的细菌病原体引起的幼年哺乳动物的全身感染的主动免疫的方法。