ANHYDROUS DICALCIUM PHOSPHATE PARTICLES AND PRODUCTION METHOD THEREOF
    90.
    发明申请
    ANHYDROUS DICALCIUM PHOSPHATE PARTICLES AND PRODUCTION METHOD THEREOF 审中-公开
    无机磷酸氢钙颗粒及其生产方法

    公开(公告)号:US20150151969A1

    公开(公告)日:2015-06-04

    申请号:US14619563

    申请日:2015-02-11

    发明人: Kazuo KITAKADO

    IPC分类号: C01B25/32

    摘要: The present invention provides anhydrous dicalcium phosphate particles which satisfies the conflicting requirements of the improvement of handling properties such as high flowability and a small bulk and the improvement of tableting properties at the same time during preparation and a method of producing the same.The method of producing anhydrous dicalcium phosphate by heating water suspensions of a phosphoric acid compound and a calcium compound at 50 to 100° C., comprises the step of: heating the phosphoric acid compound and the calcium compound, at 75° C. or higher in advance to carry out a neutralization reaction in the presence of an alkali to obtain agglomerated anhydrous dicalcium phosphate particles.

    摘要翻译: 本发明提供了无水磷酸二钙颗粒及其制备方法,其满足诸如高流动性和小体积等操作性能的改善和制备时同时改善压片性能的矛盾要求。 通过在50〜100℃下加热磷酸化合物和钙化合物的水悬浮液来生产无水磷酸氢钙的方法包括以下步骤:在75℃或更高温度下加热磷酸化合物和钙化合物 提前在碱的存在下进行中和反应,得到凝聚的无水磷酸二钙粒子。