公开(公告)号：US5352191A

公开(公告)日：1994-10-04

申请号：US960838

申请日：1992-10-14

申请人： Seizo Sunago ,  Osamu Aoki

发明人： Seizo Sunago ,  Osamu Aoki

IPC分类号： A61J1/00 ,  A61J1/20 ,  A61M5/00

CPC分类号： A61J1/2089 ,  A61J1/10 ,  A61J1/1462 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2065

摘要： A transfusion device comprising a flexible vessel containing a solvent fluid, a plugged drug container containing a drug, and a communicating portion for communicating the vessel and the container with each other, the communicating portion comprising a communicating passage disposed at a top portion of the flexible vessel and having the drug container partially or wholly fitted therein, a plugged mouth portion of the container facing downward, a membrane disposed in the communicating passage for closing the passage, and a particular puncturing needle unit mounted in the communicating passage for enabling the vessel and container to communicate with each other. When the puncturing needle unit is pressed externally through the flexible vessel, the needle breaks the membrane and the plug member of the drug container to enable the vessel and container to communicate with each other.

摘要翻译： 一种输液装置，包括容纳溶剂流体的柔性容器，容纳药物的堵塞药物容器和用于使容器和容器彼此连通的连通部分，所述连通部分包括设置在柔性容器的顶部的连通通道 容器并将药物容器部分地或全部地装配在其中，容器的面向下的堵塞的口部，设置在连通通道中用于封闭通道的膜，以及安装在连通通道中用于使容器和 容器相互通信。 当穿刺针单元通过柔性容器被向外按压时，针破坏药物容器的膜和插塞构件，以使容器和容器彼此连通。

公开(公告)号：US5334162A

公开(公告)日：1994-08-02

申请号：US31683

申请日：1993-03-15

申请人： Dale C. Harris

发明人： Dale C. Harris

IPC分类号： A61J1/05 ,  A61J1/00 ,  A61J1/06 ,  A61J1/20 ,  A61M5/24 ,  A61M5/00 ,  A61B19/00 ,  A61M37/00

CPC分类号： A61J1/2096 ,  A61J1/062 ,  A61M5/24 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2065 ,  A61M2005/2411 ,  A61M2005/2488 ,  A61M5/31553 ,  A61M5/3158 ,  A61M5/5086

摘要： A cartridge assembly for holding a lyophilized product, forming a disposable portion of a pen injector includes a cylindrical glass cartridge adapted to receive the product, a closure cap, a cartridge case, and a plunger mechanism. The closure cap is adapted to retain an elastomeric disc seal during lyophilization and includes diametrically opposed ledges. The closure cap and seal are adapted to cover a neck portion of the ampule, the neck portion having on its end a radially extending circumferential flange. The ledges of the closure cap and the flange of the neck portion allow the closure cap to remain open during lyophilization, oxygen purge and nitrogen overlay. An oval-shaped indentation formed on the inside of the closure cap aids in snapping the closure cap about the flange without crimping to retain the closure cap underneath the flange. Reconstitution of the lyophilized drug is accomplished without foaming by use of an obliquely angled connector which causes the diluent to indirectly impinge on the drug. The injection pen and cartridge assembly cooperate such that the length of travel of the plunger rod during retraction is less than the axial length of a recess in the rod tip.

摘要翻译： 用于保持冷冻干燥产品的盒式组件，形成笔式注射器的一次性部分包括适于容纳产品的圆柱形玻璃盒，封闭盖，盒壳和柱塞机构。 闭合盖适于在冻干期间保持弹性体盘密封并且包括直径相对的凸缘。 闭合盖和密封件适于覆盖安瓿的颈部，颈部在其端部上具有径向延伸的圆周凸缘。 闭合盖的凸缘和颈部的凸缘允许封闭帽在冻干，氧气吹扫和氮气覆盖期间保持打开。 形成在封闭盖的内侧上的椭圆形凹口有助于围绕凸缘卡扣闭合盖，而不会卷曲以将封闭盖保持在凸缘下方。 冻干药物的重建是通过使用倾斜成角度的连接器而实现的而不发泡，这导致稀释剂间接地侵入药物。 注射笔和墨盒组件配合使得柱塞杆在缩回期间的行程长度小于杆尖中的凹部的轴向长度。

公开(公告)号：US5329976A

公开(公告)日：1994-07-19

申请号：US948278

申请日：1992-09-21

申请人： Terry M. Haber ,  William H. Smedley ,  Clark B. Foster

发明人： Terry M. Haber ,  William H. Smedley ,  Clark B. Foster

IPC分类号： A61J1/00 ,  A61J1/20 ,  A61M1/00

CPC分类号： A61J1/2096 ,  A61J1/2089 ,  A61J1/201 ,  A61J1/2017 ,  A61J1/2055 ,  A61J1/2058 ,  A61J1/2065 ,  A61J1/2075 ,  A61J1/2082

摘要： A medication dispenser (2, 120) is used to directly fill a syringe (8, 134) with measured amounts of one or more liquid medications, typically two different types of insulin, from containers, such as vials (4, 6) and cartridges (230, 232, 234) each having a septum at one end; each cartridge has a pierceable piston (256) at the other end. The septum of each container is pierced by hollow liquid spikes (54) while hollow gas spikes (56) pierce the septum of the vial and the piston of the cartridge. Liquid is pumped out of the container and air is replaced into the container through the liquid and gas spikes. Two of the cartridges can contain a diluent (231) and a lyophilized component (233) respectively; the diluent in the first cartridge can be pumped into the second cartridge through a one-way valve to create a mixed pharmaceutical which is then pumped into the syringe, with or without another pharmaceutical.

摘要翻译： 药物分配器（2,120）用于直接将测量量的一种或多种液体药物（通常为两种不同类型的胰岛素）从容器（例如小瓶（4,6）和药筒）中填充到注射器（8,134）中 （230,232,234），每个在一端具有隔膜; 每个药筒在另一端具有可刺破的活塞（256）。 每个容器的隔膜由中空的液体尖钉（54）刺穿，而中空的气体尖钉（56）刺穿小瓶的隔膜和筒的活塞。 液体从容器中抽出，空气通过液体和气体尖峰被替换成容器。 两个盒可分别包含稀释剂（231）和冻干组分（233）; 第一盒中的稀释剂可以通过单向阀泵送到第二盒中，以产生混合药物，然后将其混合到注射器中，使用或不用另一种药物。

公开(公告)号：US4784657A

公开(公告)日：1988-11-15

申请号：US939576

申请日：1986-12-09

申请人： Lawrence A. Shimp ,  L. Brian Starling ,  Frank L. Cordova

发明人： Lawrence A. Shimp ,  L. Brian Starling ,  Frank L. Cordova

IPC分类号： A61J1/00 ,  A61J1/20 ,  A61B19/00

CPC分类号： A61J1/2096 ,  A61J1/2065

摘要： An interconnect connects a vial to a syringe for the transfer of material to the syringe or back to the vial. The interconnect includes a vial connecting mechanism and a tapered sleeve to receive the syringe. A metering port allows control of the material transfer rate and prevents partial transfers which could cause material spillage.

摘要翻译： 互连将小瓶连接到注射器以将材料转移到注射器或返回到小瓶。 互连包括小瓶连接机构和锥形套筒以接收注射器。 计量端口允许控制材料转移速率，并防止可能导致材料溢出的部分转移。

公开(公告)号：US4175597A

公开(公告)日：1979-11-27

申请号：US820512

申请日：1977-08-01

申请人： James J. Peterson

发明人： James J. Peterson

IPC分类号： A61M3/00 ,  A61J1/00 ,  A61J1/20 ,  A61M5/00 ,  B65B3/32

CPC分类号： A61J1/2096 ,  A61M5/00 ,  A61J1/2065

摘要： An irrigation solution device comprising, a syringe having a barrel, a container having a solution receiving chamber, and a barrier member extending from an upper portion of the container into the chamber. The barrier member has an inner end portion defining an opening communicating with the chamber, and defines a channel having a sufficiently large width to receive the barrel of the syringe and a sufficient length to substantially cover the syringe barrel when inserted into the channel. The device has a closure member to releasably close the channel from passage of air between the atmosphere and the chamber.

摘要翻译： 一种灌溉溶液装置，包括：具有桶的注射器，具有溶液接收室的容器和从所述容器的上部延伸到所述室中的阻挡构件。 阻挡构件具有限定与腔室连通的开口的内端部分，并且限定了具有足够大的宽度以容纳注射器的筒体的通道和足够的长度，以便当插入通道时基本上覆盖注射器筒体。 该装置具有封闭构件，用于可释放地将通道封闭在空气与气室之间。

公开(公告)号：US4092546A

公开(公告)日：1978-05-30

申请号：US690831

申请日：1976-06-08

申请人： Edward Whittum Larrabee

发明人： Edward Whittum Larrabee

IPC分类号： A61J1/00 ,  A61J1/20 ,  A61M5/00 ,  A61M5/178 ,  A61M5/32 ,  G21F5/018 ,  G21C11/00

CPC分类号： A61J1/2096 ,  A61M5/1782 ,  A61M5/1785 ,  A61M5/32 ,  G21F5/018 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2065

摘要： The disclosure of this application is directed to a protective shielding assembly suitable for use in the loading of a hypodermic syringe with radioactive material. The protective shielding device receives and securely holds, at one end, a vial which contains the material to be loaded and at its opposite end a hypodermic syringe with the needle of the syringe approximately centered with respect to the septum of the vial. Penetration of the septum of the vial is effected by moving the slidable members of the protective shielding assembly toward the vial which in turn moves the hypodermic syringe causing the needle of the hypodermic syringe to rupture the vial septum and enter the vial.

摘要翻译： 本申请的公开内容涉及适用于将放射性物质装入皮下注射器中的保护屏蔽组件。 保护屏蔽装置在一端接收并牢固地容纳包含待加载材料的小瓶，并且在其相对端容纳注射器，注射器针头相对于小瓶的隔膜大致居中。 通过将保护屏蔽组件的可滑动构件移向小瓶来实现小瓶的隔膜的穿透，该小瓶再次移动皮下注射器，使得皮下注射器的针头破裂小瓶隔膜并进入小瓶。

公开(公告)号：US3908654A

公开(公告)日：1975-09-30

申请号：US49388074

申请日：1974-08-02

申请人： RIT RECH IND THERAPEUT

发明人： LHOEST WILLY ,  HOYE ELOI VAN

IPC分类号： A61J1/00 ,  A61J1/20 ,  A61M5/00

CPC分类号： A61J1/2089 ,  A61J1/201 ,  A61J1/2065 ,  A61M5/282 ,  A61M5/284

摘要： A dispensing package for a dry biological and a liquid diluent has a hollow resilient member for containing a liquid diluent, said member being open at one end and having a nozzle at the other end with a removable closure. A plug is secured in the open end of the hollow member and a skirt integral with the plug forms a chamber for the reception of a container. A hollow needle secured in the plug is in communication with the interior of the hollow resilient member and extends into the interior of the skirt. A container for a dry biological has a pierceable stopper and is frictionally engaged by the skirt in a position such that the end of the needle within the skirt is embedded in the pierceable stopper to block the flow of liquid through the needle. The stopper is spaced away from the plug. On the further advance of the container towards the plug, the needle passes through the stopper into the container to permit the transfer of the liquid diluent into the container and then back into the tube for administration through the nozzle on the removal of the nozzle closure. A syringe type needle may be substituted for the nozzle to provide for subcutaneous or intramuscular administration.

摘要翻译： 用于干生物和液体稀释剂的分配包装具有用于容纳液体稀释剂的中空弹性构件，所述构件在一端开口并且在另一端具有可拆卸封闭件的喷嘴。 塞子固定在中空构件的开口端，并且与塞子成一体的裙部形成容纳容器的室。 固定在插头中的中空针与中空弹性构件的内部连通并延伸到裙部的内部。 用于干生物的容器具有可刺穿的止动件，并且通过裙部摩擦地接合在使得裙部内的针的端部嵌入可刺穿止动件中以阻止液体通过针的位置的位置。 塞子与插头间隔开。 在容器向插头进一步前进时，针穿过止动器进入容器，以允许液体稀释剂转移到容器中，然后返回到管中，以在去除喷嘴盖时通过喷嘴进行管理。 注射器型针可以代替喷嘴以提供皮下或肌内给药。

公开(公告)号：US12121497B2

公开(公告)日：2024-10-22

申请号：US18144577

申请日：2023-05-08

申请人： DEKA Products Limited Partnership

发明人： Gregory R. Lanier, Jr. ,  Richard J. Lanigan ,  Stephen L. Fichera ,  Dean Kamen ,  Larry B. Gray

IPC分类号： A61M5/14 ,  A61J1/14 ,  A61J1/20 ,  A61M5/142 ,  A61M5/168 ,  A61M39/08 ,  A61M5/152 ,  A61M39/00 ,  G16H20/13 ,  G16H20/17

CPC分类号： A61J1/2065 ,  A61J1/1406 ,  A61J1/2096 ,  A61M5/14224 ,  A61M5/14248 ,  A61M5/16809 ,  A61M39/08 ,  A61M2005/14268 ,  A61M5/152 ,  A61M2039/009 ,  A61M2205/0266 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3515 ,  A61M2205/3569 ,  A61M2205/581 ,  A61M2205/7536 ,  A61M2205/8212 ,  A61M2205/8237 ,  A61M2205/8262 ,  A61M2209/01 ,  A61M2209/045 ,  A61M2209/086 ,  G16H20/13 ,  G16H20/17

摘要： A method for filling a reservoir a filling assembly having a needle, and a fluid. The reservoir is in a disposable housing assembly with a septum fluidly connected to the reservoir, a septum access assembly having a first position covering the septum and a second position providing access to the septum, and a bias mechanism for biasing the septum access assembly to the first position. The method includes piercing the septum with the needle, inserting fluid to the reservoir through the needle, contacting the filling assembly to the septum access assembly, and removing the needle from the septum. Removing the needle from the septum allows the bias mechanism to move the septum access assembly from the second position to the first position. The disposable housing assembly is attached to a reusable housing assembly.

公开(公告)号：US20240325249A1

公开(公告)日：2024-10-03

申请号：US18738532

申请日：2024-06-10

申请人： Avent, Inc.

发明人： Benjamin M. Davis ,  Mark M. Costello ,  Brian Ledwith

IPC分类号： A61J1/20 ,  A61J1/14 ,  B65D41/04 ,  B65D43/16 ,  B65D47/14 ,  B65D51/24 ,  B67D7/02

CPC分类号： A61J1/2096 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1481 ,  A61J1/1487 ,  A61J1/2048 ,  A61J1/2065 ,  B65D41/0485 ,  B65D43/163 ,  B65D47/14 ,  B65D47/141 ,  B65D51/24 ,  B67D7/0288

摘要： A fluid transfer connector or adapter for coupling a container or pharmacy bottle for facilitating the transfer of fluid or medicine from the bottle to a syringe, or from the syringe to the bottle. Optionally, an additional connector can be provided for coupling the fluid transfer connector to the syringe.

公开(公告)号：US12090308B2

公开(公告)日：2024-09-17

申请号：US15871363

申请日：2018-01-15

申请人： Becton Dickinson and Company Limited

发明人： Laurie Sanders

IPC分类号： A61M5/34 ,  A61J1/14 ,  A61J1/18 ,  A61J1/20 ,  A61M5/31 ,  A61M39/10

CPC分类号： A61M5/34 ,  A61J1/1406 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2096 ,  A61M39/10 ,  A61M39/1011 ,  A61J2205/20 ,  A61M2005/3103 ,  A61M2039/1072

摘要： A syringe adapter including a housing, a cannula having a first end and second end with the second end of the cannula positioned within the housing, and a seal arrangement positioned within the housing with the seal arrangement movable within the housing between a first position where the seal arrangement is disengaged from a mating connector and a second position where the seal arrangement is engaged with a mating connector, the seal arrangement comprising a membrane. The syringe adapter including a lock mechanism, where the seal arrangement includes a lock interface that is configured to engage the lock mechanism when the seal arrangement is in the second position and when the lock mechanism is in the locked position, and where the lock mechanism is disengaged from the lock interface when the seal arrangement is in the second position and when the lock mechanism is in the unlocked position.