摘要:
A magnetic field probe (1) having a capsule (3), in which an MR-active substance (5) is encapsulated. Two coils (7, 9) are preferably arranged in the capsule (3). Advantageous production methods for magnetic field probes (1) are also described, as well as advantageous uses of the magnetic field probe (1) and methods in which magnetic field probes (1) of this kind and arrangements of magnetic field probes (1) are used.
摘要:
An implantable fluid pump system is disclosed for supporting or initiating flow inside a hollow organ through which fluid circulates, in particular the heart. The fluid pump system comprises an intracardiac module, which includes two separate fluid channels, each of which possesses an intracardiac fluid channel opening and, located opposite the latter, an extracardiac fluid channel opening, a fastening module, which provides a joining contour for purposes of joining onto the intracardiac module in a fluid-tight manner, and a fastening structure for purposes of intracorporeal fastening onto the hollow organ, and a pump module, which can be mounted in a releasable manner directly or indirectly onto the intracardiac module, and can be attached in a fluid-tight manner to the extracardiac fluid channel openings in order to produce a fluid-tight connection of both fluid channels.
摘要:
A fluid pump for pumping a fluid from an inlet toward an outlet comprises a pump body, a pump diaphragm, and a valve seat. The pump body has a first opening and a second opening. The pump diaphragm is attached to the pump body and forms a pump chamber between the pump body and the pump diaphragm. The pump chamber is fluidly connected to the inlet by the first opening and to the outlet by the second opening. The valve seat is disposed inside the pump chamber and around the second opening. The valve seat protrudes with an undeformed height from the second opening into the pump chamber in a direction toward the pump diaphragm. The valve seat has an elastic body and a gasket with a sealing surface. The pump diaphragm is deflectable and is adapted to open and close a fluidic pathway of the outlet by moving into and out of contact with the valve seat.
摘要:
The present invention discloses a matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid group.
摘要:
The present invention is inter alia concerned with a method of diagnosing Alzheimer's disease in a patient, wherein said method is based on determining the amount of at least one premature mitochondrial protein. Further, the present invention relates to the use of such a protein as marker for Alzheimer's disease. Accordingly, antibodies binding to such a preprotein may be used for diagnosing Alzheimer's disease. The present invention is based on the finding that premature mitochondrial proteins accumulate in Alzheimer's disease.
摘要:
Phase segregated block-copolymer based on repeating structural elements represented by formula I wherein PHA represents at least one block based on one or more α-hydroxy acids, PDAS represents a central block based on a dialkylsiloxane, the PDAS block has a weight average molecular weight in the range of from 4000 to 10000, the blocks PHA have a weight average molecular weight in the range of from 2000 to 10 000, the phase segregated block copolymer has a weight average molecular weight of from 40 000 to 120 000.
摘要:
The invention is related to a method and an apparatus for the automated fabrication of a molecular layer made from amphiphilic molecules, in particular lipids for a lipid bilayer membrane, in the apparatus, which has a support substrate for supporting the molecular layer, a rotation element, which can be rotated on top of the support substrate, and an actuator device, by means of which the rotation element can be automatically rotated, wherein the rotation element has an outer surface, which is formed hydrophobic at least in sections, the method having the following steps: placing a first solvent, which contains amphiphilic molecules, in a region above the support substrate; causing the automatic rotation of the rotation element above the support substrate; moving the first solvent between the support substrate and the rotation element by the interaction of the rotating rotation element with the first solvent, thus forming the molecular layer.
摘要:
The invention relates to a thermo-pneumatic actuator having a cavity defined by walls and being hermetically sealed, which is inflated with a working medium that alters the gas pressure thereof when a temperature change occurs. A wall region of the cavity is constructed as a ductile membrane, which can be deflected in at least two working positions located on both sides of a neutral position, in which the membrane is curved in opposite directions to one another. In order to alter the gas pressure in the cavity, and to adjust the membrane from one working position to the other working position, a tempering device is heat-conductively connected to the working medium. In the neutral position, the membrane is compressively loaded such that respectively, it maintains its position in both working positions if no outside force impacts the membrane.
摘要:
The present invention discloses a matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid group.
摘要:
Medicament for the treatment or the prevention of a bacterial infection, characterized in that it contains at least one polypeptide selected from the group of SEQ ID NO: 1 to SEQ ID NO: 9, and contiguous fragments thereof, wherein said at least one polypeptide or contiguous fragment thereof induces opsonic antibodies in a patient in need thereof. The polypeptides or the contiguous fragments thereof according to the present invention can be used for the preparation of a vaccine against an infection against Enterococcus.