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    Test strip with integrated lancet
    3.
    发明授权
    Test strip with integrated lancet 有权
    带集成刺血针的试纸

    公开(公告)号：US08636672B2

    公开(公告)日：2014-01-28

    申请号：US11711621

    申请日：2007-02-28

    申请人： Gary Neel ,  Allan Javier Caban

    发明人： Gary Neel ,  Allan Javier Caban

    IPC分类号： A61B5/151 ,  A61B5/15

    CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/15019 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15107 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/1519 ,  A61B5/157 ,  A61B2562/0295

    摘要： The present disclosure provides methods and systems to collect blood from a patient using a lancet integrated with a test strip. The present disclosure provides integrated test strips having an integrated lancet, as well as meters for actuating the lancet integrated within a test strip. The analyte test strip comprises a first test strip substrate material and a second test strip substrate material. At least one test strip substrate material comprises an elongate cavity. The test strip further comprises a reaction test site for testing analyte concentrations in blood. The test strip further comprises at least one opening communicating with the at least one cavity.

    摘要翻译： 本公开提供了使用与测试条整合的刺血针从患者采集血液的方法和系统。 本公开提供具有集成的柳叶刀的集成测试条以及用于致动集成在测试条中的刺血针的计量器。 分析物测试条包括第一测试条基材和第二测试条基材。 至少一个测试条衬底材料包括细长空腔。 测试条还包括用于测试血液中分析物浓度的反应测试位点。 测试条还包括与至少一个空腔连通的至少一个开口。

    Biosensor manufacturing method
    4.
    发明授权
    Biosensor manufacturing method 有权
    生物传感器制造方法

    公开(公告)号：US08128981B2

    公开(公告)日：2012-03-06

    申请号：US11783568

    申请日：2007-04-10

    申请人： Natasha Popovich ,  Dennis Slomski ,  David Deng

    发明人： Natasha Popovich ,  Dennis Slomski ,  David Deng

    IPC分类号： G01N1/28

    CPC分类号： G01N27/3272

    摘要： A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique.

    摘要翻译： 描述具有第一导电部件的生物传感器，其中第一导电部件包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第二处理技术形成的至少一个边界。 生物传感器还可以具有包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第三处理技术形成的至少一个边界的第二导电部件。 此外，生物传感器具有包括由第二处理技术形成的至少一个边界和由与第二处理技术不相同的第三处理技术形成的至少一个边界的第三导电成分。

    System and methods for determination of analyte concentration using time resolved amperometry
    5.
    发明授权
    System and methods for determination of analyte concentration using time resolved amperometry 有权
    使用时间分辨安培法测定分析物浓度的系统和方法

    公开(公告)号：US08101062B2

    公开(公告)日：2012-01-24

    申请号：US12410048

    申请日：2009-03-24

    申请人： David Deng

    发明人： David Deng

    IPC分类号： G01N27/26

    CPC分类号： A61B5/14532 ,  A61B5/1486 ,  A61B5/1495 ,  A61B2562/0295 ,  G01N27/3273 ,  Y10S435/817

    摘要： A method for determining a concentration of an analyte is disclosed. The method includes applying a potential excitation to a fluid sample containing an analyte and determining if a current decay curve associated with the fluid sample has entered an analyte depletion stage. The method also includes measuring a plurality of current values associated with the fluid sample during the analyte depletion stage and calculating an analyte concentration based on at least one of the plurality of current values.

    摘要翻译： 公开了一种用于测定分析物浓度的方法。 该方法包括对含有分析物的流体样品施加势能激励，并确定与流体样品相关联的电流衰减曲线是否已进入分析物耗尽阶段。 该方法还包括在分析物耗尽阶段期间测量与流体样品相关联的多个电流值，并且基于多个电流值中的至少一个来计算分析物浓度。

    System and methods for determination of analyte concentration using time resolved amperometry
    6.
    发明授权
    System and methods for determination of analyte concentration using time resolved amperometry 有权
    使用时间分辨安培法测定分析物浓度的系统和方法

    公开(公告)号：US08088272B2

    公开(公告)日：2012-01-03

    申请号：US12179853

    申请日：2008-07-25

    申请人： David Deng

    发明人： David Deng

    IPC分类号： G01N27/26

    CPC分类号： G01N27/3273

    摘要： This invention is a method for determining a concentration of an analyte. The steps include applying a potential excitation to a fluid sample containing an analyte, and measuring a current associated with the potential excitation at a plurality of time-points. The method also includes calculating an analyte concentration based on the measured current and a calibration curve, wherein the calibration curve is selected from a plurality of calibration curves and each calibration curve is associated with a time-segment selected from a plurality of time-segments.

    摘要翻译： 本发明是用于测定分析物浓度的方法。 这些步骤包括对含有分析物的流体样品施加潜在的激发，并在多个时间点测量与潜在激发相关的电流。 该方法还包括基于测量的电流和校准曲线计算分析物浓度，其中校准曲线选自多个校准曲线，并且每个校准曲线与从多个时间段中选择的时间段相关联。

    Reagent compositions for use in electrochemical detection
    7.
    发明授权
    Reagent compositions for use in electrochemical detection 有权
    用于电化学检测的试剂组合物

    公开(公告)号：US08062490B2

    公开(公告)日：2011-11-22

    申请号：US12724280

    申请日：2010-03-15

    申请人： Douglas E. Bell ,  Michele Albino

    发明人： Douglas E. Bell ,  Michele Albino

    IPC分类号： G01N27/327 ,  G01N21/00

    CPC分类号： C12Q1/006 ,  Y10T29/53204

    摘要： Biological reagent compositions with improved sensitivity to the concentration of blood glucose in patient samples for use in measuring systems and methods. The reagent compositions comprise a glucose oxidoreductase enzyme, a flavin nucleoside coenzyme and a mediator formulation. The mediator formulation comprises at least one electroactive organic molecule and at least one coordination complex.

    摘要翻译： 对患者样品中血糖浓度的敏感性提高的生物试剂组合物用于测量系统和方法。 试剂组合物包含葡萄糖氧化还原酶，黄素核苷辅酶和介体制剂。 介体制剂包含至少一种电活性有机分子和至少一种配位络合物。