公开(公告)号：US20180220964A1

公开(公告)日：2018-08-09

申请号：US15750952

申请日：2016-08-05

Applicant: SHARP KABUSHIKI KAISHA ,  OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： HIROSHI SAKAYA ,  TETSUYA HAYASHI ,  AZUSA NAKANO ,  SHUNSUKE SHIMAMURA ,  TERUMASA SHIMADA

IPC: A61B5/00 ,  A61B5/0408 ,  A61B5/0428

CPC classification number: A61B5/6831 ,  A61B5/0408 ,  A61B5/04286 ,  A61B5/4872 ,  A61B5/6823 ,  A61B2503/40 ,  A61B2562/0209 ,  A61D13/00

Abstract: A wearable instrument is provided that measures biological information over an extended period of time by enabling an electrode to be readily pressed to an axilla of an animal. The wearable instrument includes: electrodes to be placed under the left and right axillae of a dog to produce an electrocardiogram; pull-up straps to be placed in direct contact with the axilla to press the electrodes onto the axilla; and a cinch strap placed across the anterior chest of the dog to draw the left and right sections of the pull-up strap together.

公开(公告)号：US11155775B2

公开(公告)日：2021-10-26

申请号：US15779951

申请日：2016-11-07

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION ,  NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY

Inventor： Masaya Hagiwara ,  Tomohiro Kawahara

IPC: C12M1/00 ,  C12M1/12

Abstract: The present invention provides a cell culture vessel or a sample cell for observation use that makes it possible to observe three-dimensionally-cultured cells from various angles. The cell culture vessel or the sample cell for observation use according to the present invention is characterized by being equipped with a culture gel in which a cell or cell tissue is embedded and a first vessel which encloses the culture gel, wherein a space in the first vessel is filled with the culture gel; and the first vessel has a light-permeable window made from a hydrogel.

公开(公告)号：US10208246B2

公开(公告)日：2019-02-19

申请号：US14901496

申请日：2014-10-21

Applicant: OSAKA PREFECTURE UNIVERSITY Public Corporation ,  YASU MEDICAL IMAGING TECHNOLOGY CO., LTD.

Inventor： Taketoshi Kawai ,  Fumiaki Kunimoto

IPC: C09K11/62 ,  B32B37/10 ,  C09K11/61

Abstract: An additive containing an ion as a luminescence center is added to alkali halide powder as a base material. Mechanical energy for applying an impact force, a shearing force, a shear stress, or a friction force is applied so as to grind or mix the alkali halide powder and the additive. The ion as the luminescence center is doped into the alkali halide as the base material so as to obtain alkali halide-based scintillator powder. With this process, the alkali halide-based scintillator powder can be manufactured at a room temperature in the atmospheric air without any complicated condition control or any process at a high temperature under high vacuum and a large-sized scintillator sheet can be produced.

公开(公告)号：US09797842B2

公开(公告)日：2017-10-24

申请号：US13992475

申请日：2011-12-08

Applicant: Shiho Tokonami ,  Takuya Iida ,  Yojiro Yamamoto ,  Hiroshi Shiigi ,  Tsutomu Nagaoka

Inventor： Shiho Tokonami ,  Takuya Iida ,  Yojiro Yamamoto ,  Hiroshi Shiigi ,  Tsutomu Nagaoka

IPC: G01N21/65 ,  G01N21/552 ,  G01N33/543

CPC classification number: G01N21/658 ,  G01N21/554 ,  G01N33/54346

Abstract: Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.

公开(公告)号：US09512534B2

公开(公告)日：2016-12-06

申请号：US13974113

申请日：2013-08-23

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION ,  NITTO BOSEKI CO., LTD.

Inventor： Kazuo Kondo ,  Takeyasu Saito ,  Naoki Okamoto ,  Masaru Bunya ,  Minoru Takeuchi

IPC: C25D5/18 ,  H01L21/768 ,  C25D3/38 ,  H01L21/288

CPC classification number: C25D5/18 ,  C25D3/38 ,  H01L21/2885 ,  H01L21/76861 ,  H01L21/76877 ,  H01L21/76898

Abstract: There is provided a method of well filling copper in a conductivity-rendered non-through hole having an aspect ratio (depth/hole diameter) of 5 or more on a substrate in a short period of time, and the method comprises using an acidic copper plating bath comprising a water-soluble copper salt, sulfuric acid, chlorine ion, a brightener and a copolymer of diallylamines and sulfur dioxide and filling copper in the non-through hole by periodic current reversal copper plating.

Abstract translation: 提供了一种在短时间内在衬底上具有5或更大的纵横比（深度/孔直径）的导电性非贯通孔中充满铜的方法，该方法包括使用酸性铜 包含水溶性铜盐，硫酸，氯离子，增白剂和二烯丙基胺和二氧化硫的共聚物的电镀浴，并通过周期性电流反转铜电镀在非贯通孔中填充铜。

公开(公告)号：US09371574B2

公开(公告)日：2016-06-21

申请号：US13395773

申请日：2010-09-14

Applicant: Yasuyuki Kaneno ,  Takayuki Takasugi

Inventor： Yasuyuki Kaneno ,  Takayuki Takasugi

IPC: C22F1/10 ,  C22C19/03

CPC classification number: C22F1/10 ,  C22C19/03 ,  Y10T428/12

Abstract: The present invention provides a structural material having enhanced ductility characteristics at high temperatures and enhanced strength characteristics. The present invention provides an Ni3(Si, Ti)-based intermetallic compound characterized by containing from 25 to 500 ppm by weight of B with respect to a weight of an intermetallic compound having a composition of 100% by atom in total consisting of Ni as a main component, from 7.5 to 12.5% by atom of Si, from 4.5 to 11.5% by atom of Ti and from 0.5 to 5.0% by atom of W.

Abstract translation: 本发明提供了一种在高温下具有增强的延展性特征和增强的强度特性的结构材料。 本发明提供了一种Ni3（Si，Ti）基金属间化合物，其特征在于，相对于总计100重量％的组成为金属间化合物的重量，含有25〜500重量ppm的B，由Ni作为 主要成分为硅原子为7.5〜12.5原子％，Ti为4.5〜11.5原子％，W为0.5〜5.0原子％

公开(公告)号：US20160123968A1

公开(公告)日：2016-05-05

申请号：US14894452

申请日：2014-05-30

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION

Inventor： Takuya IIDA ,  Shiho TOKONAMI

IPC: G01N33/543 ,  G01N21/21 ,  G01N21/65 ,  G01N33/553 ,  G01N33/53

CPC classification number: G01N33/54346 ,  C12Q1/6834 ,  C12Q2563/155 ,  C12Q2565/628 ,  G01N21/21 ,  G01N21/554 ,  G01N21/658 ,  G01N33/5308 ,  G01N33/553 ,  G01N2201/061 ,  G01N2201/0683

Abstract: A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.

Abstract translation: 检测装置检测可能包含在样本中的分析物。 检测装置包括多个金纳米颗粒，光学捕获光源，照明光源，物镜，图像拾取装置和计算单元。 多个金纳米颗粒各自用探针DNA修饰，允许分析物特异性地粘附于其上。 光捕获光源发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜聚焦并将偏振光引入含有样品和多个金纳米颗粒的液体中。 摄像装置接收来自液体的光。 计算单元基于从图像拾取装置接收的信号检测分析物。

公开(公告)号：US20150368655A1

公开(公告)日：2015-12-24

申请号：US14655228

申请日：2013-12-25

Applicant: OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION ,  euglena Co., Ltd.

Inventor： Masami Nakazawa ,  Daiki Haruguchi ,  Mitsuhiro Ueda ,  Kazutaka Miyatake

IPC: C12N15/79

CPC classification number: C12N15/79 ,  C12N15/8205 ,  C12N15/8209

Abstract: A Euglena carrying a foreign gene of interest in an expressible manner is provided.A Euglena carrying a drug resistance gene and a foreign gene of interest in an expressible manner.

Abstract translation: 提供以可表达的方式携带感兴趣的外来基因的Euglena。 以可表达的方式携带耐药性基因和感兴趣的外源基因的Euglena。

公开(公告)号：US09206461B2

公开(公告)日：2015-12-08

申请号：US14003613

申请日：2012-03-06

Applicant: Shiho Tokonami ,  Hiroshi Shiigi ,  Tsutomu Nagaoka ,  Mugihei Ikemizu ,  Mari Takahashi

Inventor： Shiho Tokonami ,  Hiroshi Shiigi ,  Tsutomu Nagaoka ,  Mugihei Ikemizu ,  Mari Takahashi

IPC: C12Q1/04 ,  G01N33/569 ,  G01N33/543 ,  C25D5/00

CPC classification number: C12Q1/04 ,  C25D5/00 ,  G01N33/5438 ,  G01N33/569 ,  Y10T428/24479

Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.

Abstract translation: 本发明提供了一种传感器，其包括具有检测电极和聚合物层的检测单元，该检测单元设置在检测电极上，并且包括具有与待检测微生物的空间结构互补的三维结构的模具。 传感器基于在模具中捕获微生物的状态来检测微生物。 聚合物层是通过以下制造方法形成的：包括：在待检测微生物存在下聚合单体的聚合步骤，以形成在检测电极上捕获微生物的聚合物层; 部分破坏在聚合物层中捕获的微生物的破坏步骤; 以及使聚合物层过氧化以从聚合物层中释放微生物的过氧化步骤。

公开(公告)号：US09173634B2

公开(公告)日：2015-11-03

申请号：US13637999

申请日：2011-03-25

Applicant: Toshiyuki Matsunaka ,  Hiromichi Horinaka ,  Hiroyasu Morikawa ,  Tomohiro Ogawa

Inventor： Toshiyuki Matsunaka ,  Hiromichi Horinaka ,  Hiroyasu Morikawa ,  Tomohiro Ogawa

IPC: A61B8/08 ,  A61B5/00 ,  A61B8/14

CPC classification number: A61B8/0858 ,  A61B5/4872 ,  A61B8/14 ,  A61B8/5223

Abstract: A fatty tissue image display device includes a light source, an ultrasonic wave transmission/reception mechanism, an analysis unit which calculates a velocity change of ultrasonic waves after irradiation with a heating beam as compared to before irradiation with light, a display control unit which displays the distribution of the calculated velocity change of the ultrasonic waves, a designation unit which waits for the designation of a region of interest, a histogram calculation unit which, based on luminance information or color information within the designated region of interest, calculates the histograms of a fatty region showing a negative velocity change of the ultrasonic waves and a normal region showing a positive velocity change of the ultrasonic waves, and an index calculation unit which, from the calculated histograms of the fatty and normal regions, calculates a fatty change index that is an index of a proportion of fatty tissue.

Abstract translation: 脂肪组织图像显示装置包括光源，超声波发送/接收机构，分析单元，其计算与用光照射之前的加热束照射之后的超声波的速度变化;显示控制单元，其显示 计算超声波的速度变化的分布，等待感兴趣区域的指定的指定单元，基于指定的感兴趣区域内的亮度信息或颜色信息的直方图计算单元计算直方图 示出超声波的负速度变化的脂肪区域和表示超声波的正速度变化的正常区域，以及指标计算单元，根据计算出的脂肪和正常区域的直方图，计算脂肪变化指数， 是脂肪组织比例的指标。