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    Method of communication between functional blocks in a system-on-chip and system-on-chip thereof
    1.
    发明授权
    Method of communication between functional blocks in a system-on-chip and system-on-chip thereof 有权

    公开(公告)号：US12255997B2

    公开(公告)日：2025-03-18

    申请号：US17799898

    申请日：2020-02-26

    Applicant: Agency for Science, Technology and Research

    Inventor： Ming Ming Wong ,  Anh Tuan Do ,  Kevin Tshun Chuan Chai

    IPC: G06F21/42 ,  H04L9/00 ,  H04L9/08 ,  H04L9/12 ,  G06F12/14 ,  G06F21/32

    Abstract: There is provided a method of communication between functional blocks in a system-on-chip. The method includes: exchanging a respective public key between a first functional block and a second functional block in the system-on-chip (SoC) for a communication therebetween, the first functional block being a transmitter of the communication and the second function block being a receiver of the communication; generating, at the first functional block, a first code based on the public key of the second functional block; generating, at the second functional block, a second code based on the public key of the first functional block; obfuscating, at the first functional block, an address associated with the communication based on the first code to produce an obfuscated address; transmitting, at the first functional block, the obfuscated address to the second functional block via an interconnect communication infrastructure in the system-on-chip; receiving, at the second functional block, the obfuscated address from the first functional block via the interconnect communication infrastructure; and deobfuscating, at the second functional block, the obfuscated address received based on the second code to produce a deobfuscated address associated with the communication. There is also provided a corresponding system-on-chip.

    A METHOD OF TREATING ACUTE MYELOID LEUKEMIA
    3.
    发明申请
    A METHOD OF TREATING ACUTE MYELOID LEUKEMIA 有权

    公开(公告)号：US20250043270A1

    公开(公告)日：2025-02-06

    申请号：US18715366

    申请日：2022-11-30

    Applicant: Agency for Science, Technology and Research

    Inventor： Amit Singhal ,  Kumar Dilip

    IPC: C12N15/10 ,  A61K35/28 ,  A61K45/06 ,  A61P35/02 ,  C12N5/0789

    Abstract: There is provided a genetically modified cell wherein at least one gene has been deleted from the cell and the gene is selected from the group consisting of p50, p52, p65, c-Rel, and RelB. Also disclosed are methods of identifying a target for treating acute myeloid leukemia (AML) in a subject, methods of treating acute myeloid leukemia (AML) in a subject in need thereof, comprising inhibiting the activity of an NF-KB pathway. Also provided is an ATP13A2 inhibiting agent for use in therapy or medicine, for use in treating AML, and in the manufacture of a medicament for treating AML.

    MULTIMODAL MICROSCOPY SYSTEM
    4.
    发明申请
    MULTIMODAL MICROSCOPY SYSTEM 有权

    公开(公告)号：US20250028159A1

    公开(公告)日：2025-01-23

    申请号：US18712553

    申请日：2022-11-23

    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    Inventor： Shuyan ZHENG ,  Malini OLIVO

    IPC: G02B21/12 ,  A61B1/04 ,  A61B1/07 ,  G01N21/64 ,  G02B21/16 ,  G02B21/26 ,  G02B21/36 ,  G02B27/14 ,  G02B27/30

    Abstract: Embodiments of the invention provide for a multimodal microscopy system. The multimodal microscopy system may include an illumination module configured to provide a light beam to a sample under test via a delivery path; and an optical arrangement configured to receive the light beam from the sample through a detection path to generate a microscopy image of the sample. The optical arrangement may be operable to switch among a plurality of imaging modalities using the detection path shared by the plurality of imaging modalities. The plurality of imaging modalities may include brightfield microscopy, fluorescent microscopy, and endoscopic microscopy. The multimodal microscopy system may be a multimodal hyperspectral microscopy system.

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