3D microelectrode device for live tissue applications
    8.
    发明授权
    3D microelectrode device for live tissue applications 有权
    用于活组织应用的3D微电极装置

    公开(公告)号:US09248273B2

    公开(公告)日:2016-02-02

    申请号:US13919013

    申请日:2013-06-17

    摘要: A 3D microelectrode device includes a flexible substrate containing poly-dimethyl siloxane (PDMS). The device may be fabricated in a miniature form factor suitable for attachment to a small organ such as a lateral gastrocnemius muscle of a live rat. In addition to providing a miniaturized, conformable attachment, the device provides an anchoring action via one or more microelectrodes, each having an insertable tip particularly shaped to provide the anchoring action. Furthermore, a base portion of each of the microelectrodes is embedded inside conductive poly-dimethyl siloxane (cPDMS). The cPDMS is contained in a pad that is coupled to a conductive track embedded in the flexible substrate. Embedding of the base portion inside the cPDMS material not only allows the microelectrode to bend in various directions, but also provides good electrical conductivity while eliminating the need for attachment processes using solder or epoxy adhesives.

    摘要翻译: 3D微电极装置包括含有聚二甲基硅氧烷(PDMS)的柔性基材。 该装置可以以适于附着到活体大鼠的腓肠肌外侧的小器官的微型形状来制造。 除了提供小型化,顺应性附件之外,该装置通过一个或多个微电极提供锚定作用,每个微电极具有特别成形以提供锚定作用的可插入尖端。 此外,每个微电极的基底部分嵌入导电性聚二甲基硅氧烷(cPDMS)内部。 cPDMS包含在耦合到嵌入在柔性基板中的导电轨道的焊盘中。 在cPDMS材料内部嵌入基部不仅允许微电极在各个方向上弯曲,而且还提供良好的导电性,同时不需要使用焊料或环氧树脂粘合剂的连接工艺。