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公开(公告)号：US20130274597A1
公开(公告)日：2013-10-17
申请号：US13878729
申请日：2011-10-12
CPC分类号： A61B1/00165 , A61B1/00096 , A61B1/00117 , A61B1/00172 , A61B1/005 , A61B5/0066 , A61B5/0068 , A61B5/0084 , G02B23/2469 , G02B23/2476 , G02B26/103
摘要： A scanner for an endoscope comprising: a scanning mechanism comprising a light transmitter and arranged to move the light transmitter to perform a scan; a lens system arranged to optically couple the light transmitter to a target during a scan; a first housing which houses at least a first portion of the lens system; a second housing which houses at least the fibre scanning mechanism; and a bendable joint joining the first and second housings such that in a scanning configuration the bendable joint joins the first and second housings so that optical elements in the first and second housings are aligned at a working separation, the bendable joint arranged to bend in response to insertion forces applied to the scanner during insertion of the scanner and revert to the scanning configuration in the absence of insertion forces.
摘要翻译： 一种用于内窥镜的扫描器，包括：扫描机构，包括光发射器，并被布置成移动所述光发射器以执行扫描; 透镜系统，布置成在扫描期间将光发射器光学耦合到目标; 容纳透镜系统的至少第一部分的第一壳体; 至少容纳光纤扫描机构的第二壳体; 以及连接所述第一和第二壳体的可弯曲接头，使得在扫描构造中，所述可弯曲接头连接所述第一和第二壳体，使得所述第一和第二壳体中的光学元件在工作分离处对准，所述可弯曲接头被布置成响应于弯曲 在插入扫描仪期间施加到扫描仪的插入力，并且在没有插入力的情况下恢复到扫描配置。
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公开(公告)号：US07123790B2
公开(公告)日：2006-10-17
申请号：US10533440
申请日：2003-10-29
CPC分类号： G01Q10/06 , G02B6/3504 , G02B6/3572 , G02B21/002 , G02B23/2407 , G02B26/101
摘要： A scanning apparatus and method, the apparatus comprising: a light transmission means (90) having an exit tip; first and second drive means (92,94) for resonantly driving the light transmission means (90) in orthogonal directions; wherein the first and second drive means (92,94) are operable to move the tip in an elliptical pattern while varying the eccentricity of the elliptical pattern, whereby a portion of the elliptical pattern having a centre on the minor axis of the elliptical pattern approximates—at least in appearance—a raster pattern.
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公开(公告)号：US08449825B2
公开(公告)日：2013-05-28
申请号：US12940564
申请日：2010-11-05
IPC分类号： G01N27/00
CPC分类号： G01N33/502 , B01L3/5025 , B01L2300/0829 , B01L2300/0851 , B01L2300/0893 , B01L2300/16 , G01N27/28 , G01N33/48728 , G01N33/5438 , G01N33/6872 , G01N2500/04 , G01N2500/10 , Y10T29/49826
摘要： The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.
摘要翻译： 本发明涉及一种包括生物膜和多孔或穿孔基底，生物膜，基底，高通量筛选，结构膜和基底的制备方法以及筛选大量试验的方法的结构 化合物在短时间内。 更具体地说，涉及一种结构，该结构包括附着于多孔或多孔基底的生物膜，能够将高电阻密封粘附到诸如多孔玻璃的基底上的生物膜，以及形成主要具有离子通道或转运体 兴趣，用于确定测试化合物对离子通道或转运蛋白活性的影响的高通量筛选，用于制造结构，膜和底物的方法，以及用于监测膜中的离子通道或转运蛋白活性的方法。
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公开(公告)号：US07920312B2
公开(公告)日：2011-04-05
申请号：US11855001
申请日：2007-09-13
IPC分类号： G02B26/08
CPC分类号： A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , G02B21/0036 , G02B23/2407 , G02B26/103
摘要： A scanning apparatus and method, the apparatus comprising a light transmitter, a mount for supporting the light transmitter located remotely from its exit tip, a drive for driving the light transmitter to vibrate resonantly in a first direction and to vibrate non-resonantly in a second direction orthogonal to the first direction, and a synchronizer for synchronizing vibration of the light transmitter in the first and second directions so that the exit tip of the light transmitter executes a scan pattern. The drive applies a driving force to the light transmitter between the mount and the exit tip.
摘要翻译： 一种扫描装置和方法，所述装置包括光发射器，用于支撑远离其出射尖端的光发射器的安装件，用于驱动光发射器以在第一方向上共振地振动并且在第二方向上非谐振地振动的驱动器 以及同步器，用于使光发射器在第一和第二方向上的振动同步，使得光发射器的出射端执行扫描图案。 驱动器将驱动力施加到安装座和出口尖端之间的光发射器。
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公开(公告)号：US20090015894A1
公开(公告)日：2009-01-15
申请号：US11855001
申请日：2007-09-13
IPC分类号： G02B26/10
CPC分类号： A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0084 , G02B21/0036 , G02B23/2407 , G02B26/103
摘要： A scanning apparatus and method, the apparatus comprising a light transmitter, a mount for supporting the light transmitter located remotely from its exit tip, a drive for driving the light transmitter to vibrate resonantly in a first direction and to vibrate non-resonantly in a second direction orthogonal to the first direction, and a synchronizer for synchronizing vibration of the light transmitter in the first and second directions so that the exit tip of the light transmitter executes a scan pattern. The drive applies a driving force to the light transmitter between the mount and the exit tip.
摘要翻译： 一种扫描装置和方法，所述装置包括光发射器，用于支撑远离其出射尖端的光发射器的安装件，用于驱动光发射器以在第一方向上共振地振动并且在第二方向上非谐振地振动的驱动器 以及同步器，用于使光发射器在第一和第二方向上的振动同步，使得光发射器的出射端执行扫描图案。 驱动器将驱动力施加到安装座和出口尖端之间的光发射器。
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公开(公告)号：US5543642A
公开(公告)日：1996-08-06
申请号：US476058
申请日：1995-06-07
申请人： Gerard Byrne
发明人： Gerard Byrne
CPC分类号： H01L27/0218 , H01L29/0847
摘要： A p-channel transistor has a drain electrode (12), a source electrode (13), a gate electrode (16) and a bulk electrode (14), the drain and source electrodes (12, 13) being constructed as p-regions in an n-well (10) and the well (10) itself being embedded in a surrounding p-region.The bulk electrode is simultaneously the well terminal and is connected to the source electrode (13), while the drain electrode (12) is connected to the positive pole (U.sup.+) of the operating voltage. This arrangement confers a reliable resistance to polarity reversal in conjunction with a minimum area requirement; even at relatively high temperatures, only negligible leakage currents flow; and, there is a need only for a single well (10) on which it is also possible to accommodate still other components.
摘要翻译： P沟道晶体管具有漏电极（12），源电极（13），栅极电极（16）和体电极（14），所述漏极和源电极（12,13）被构造为p区 在n阱（10）中，阱（10）本身嵌入在周围的p区中。 体电极同时是阱端子并连接到源电极（13），而漏电极（12）连接到工作电压的正极（U +）。 这种布置赋予极性反转的可靠阻力以及最小面积要求; 即使在相对高的温度下，只有可忽略的漏电流流过; 并且仅需要单孔（10），其中也可以容纳其它组件。
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公开(公告)号：US5852375A
公开(公告)日：1998-12-22
申请号：US797565
申请日：1997-02-07
IPC分类号： H03K19/003 , H03K3/00 , H02H3/20
CPC分类号： H03K19/00315
摘要： An integrated circuit has an I/O circuit that is connected to an I/O PAD. The I/O PAD may have greater voltage than the VDD associated with the integrated circuit so there is provided a switching circuit that is connected between the VDD and the I/O PAD. An output circuit is also provided that comprises n-channel transistors connected between the PAD and the ground. There is a cascode arrangement of p-channel transistors connected between the I/O PAD and VDD.
摘要翻译： 集成电路具有连接到I / O PAD的I / O电路。 I / O PAD可能具有比与集成电路相关的VDD更大的电压，因此提供了连接在VDD和I / O PAD之间的开关电路。 还提供了包括连接在PAD和地之间的n沟道晶体管的输出电路。 在I / O PAD和VDD之间连接有p沟道晶体管的共源共栅布置。
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8.发明授权Integrated circuit with an onboard regulator having an optional external pass transistor 失效具有板载调节器的集成电路具有可选的外部通过晶体管
公开(公告)号：US5828205A
公开(公告)日：1998-10-27
申请号：US810428
申请日：1997-03-04
申请人： T. Gerard Byrne
发明人： T. Gerard Byrne
摘要： An integrated circuit has an on-chip voltage regulator circuit. The voltage regulator circuit includes a control circuit, a pass element and a control connection and also provided is a connection for connecting an external pass element to the voltage regulator. There is a switch circuit that when an external pass element is connected to the voltage regulator, the switch circuit will turn off the internal pass element.
摘要翻译： 集成电路具有片上稳压电路。 电压调节器电路包括控制电路，通过元件和控制连接，并且还提供用于将外部通过元件连接到电压调节器的连接。 有一个开关电路，当外部通过元件连接到电压调节器时，开关电路将关闭内部通过元件。
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公开(公告)号：US5460028A
公开(公告)日：1995-10-24
申请号：US341230
申请日：1994-12-05
申请人： Peter Werner , Hermann Hemminger , Beate Glockner , Gerard Byrne , Stephan Johne
发明人： Peter Werner , Hermann Hemminger , Beate Glockner , Gerard Byrne , Stephan Johne
IPC分类号： G01N27/409 , F02D41/14 , F02D41/24 , G01N27/26 , F02B3/08
CPC分类号： F02D41/28 , F02D41/1493 , F02D41/1456
摘要： The invention is directed to a circuit for conditioning the output signal of a measuring sensor for further processing in a control apparatus which has a fixed ground potential which does not necessarily correspond to the ground potential of the measuring sensor. A conditioning circuit is provided which can be integrated on a chip and has the following characteristics. The conditioning circuit compensates for the fluctuating ground offset between exhaust gas probe and control apparatus ground when utilizing an exhaust gas probe burdened with a potential. The circuit arrangement includes an external circuit which can be changed to influence the input signal to the conditioning circuit. With this changeable external circuit, the output signal of the circuit arrangement can be so modified that the control apparatus outputs an output voltage with offset and an output voltage without offset. In the case of the external circuit for an output voltage without offset, an offset is impressed upon the input voltage which is then again subtracted at the output with an amplification factor so that the absolute value of the impressed offset has no influence on the output voltage.
摘要翻译： 本发明涉及一种用于调节测量传感器的输出信号的电路，用于在具有固定接地电位的控制装置中进一步处理，该固定接地电位不一定对应于测量传感器的接地电位。 提供了可以集成在芯片上并具有以下特征的调理电路。 调理电路补偿了排气探头与控制装置接地之间波动的接地偏移，并利用负载有潜力的排气探头。 电路装置包括可以改变以影响调节电路的输入信号的外部电路。 利用这种可变的外部电路，可以对电路装置的输出信号进行如此修改，使得控制装置输出具有偏移的输出电压和没有偏移的输出电压。 在没有偏移的输出电压的外部电路的情况下，在输入电压上施加偏移，然后在放大系数的输出处再次减去输入电压，使得被施加的偏移的绝对值对输出电压没有影响 。
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公开(公告)号：US09456734B2
公开(公告)日：2016-10-04
申请号：US13878729
申请日：2011-10-12
CPC分类号： A61B1/00165 , A61B1/00096 , A61B1/00117 , A61B1/00172 , A61B1/005 , A61B5/0066 , A61B5/0068 , A61B5/0084 , G02B23/2469 , G02B23/2476 , G02B26/103
摘要： A scanner for an endoscope comprising: a scanning mechanism comprising a light transmitter and arranged to move the light transmitter to perform a scan; a lens system arranged to optically couple the light transmitter to a target during a scan; a first housing which houses at least a first portion of the lens system; a second housing which houses at least the fiber scanning mechanism; and a bendable joint joining the first and second housings such that in a scanning configuration the bendable joint joins the first and second housings so that optical elements in the first and second housings are aligned at a working separation, the bendable joint arranged to bend in response to insertion forces applied to the scanner during insertion of the scanner and revert to the scanning configuration in the absence of insertion forces.
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