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公开(公告)号：US09995623B2
公开(公告)日：2018-06-12
申请号：US14775299
申请日：2013-12-03
Applicant: Integrated Plasmonics Corporation
Inventor： Robert Joseph Walters
CPC classification number: G01J3/0208 , G01J3/0216 , G01J3/0224 , G01J3/0229 , G01J3/0264 , G01J3/027 , G01J3/0272 , G01J3/0289 , G01J3/10 , G01J3/12 , G01J3/18 , G01J3/2803 , G01J3/42 , G01J2003/1213 , G01N21/255 , G01N2021/3122
Abstract: A spectroscopic device, which may be a handheld spectroscopic light source, which uses ambient light as a primary broadband light source, but which may be supplemented with an auxiliary light source to supplement band regions which may be deficient in the broad band source. The spectroscopic device makes use of a number of parallel control channels to monitor for sufficient light and to compensate for variations in the input light levels.
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公开(公告)号：US09976963B2
公开(公告)日：2018-05-22
申请号：US14095971
申请日：2013-12-03
Applicant: Integrated Plasmonics Corporation
Inventor： Nilesh Dinbandhu Shah , Albert Jerwen Mach
CPC classification number: G01N21/8483 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2300/043 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/0825 , B01L2300/0864 , B01L2300/0883 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/049
Abstract: A microcuvette cartridge for optical measurement of a specimen includes: a substrate having a recess on an upper surface thereof to receive a fluid specimen therein, the substrate having a plurality of cavities therein to receive the fluid specimen transported from the recess, the substrate further defining a plurality of channels communicating with the recess and with the plurality of cavities, respectively, to transport the fluid specimen from the recess to the plurality of cavities, said substrate further having one or more of windows at positions corresponding to the plurality of cavities, the windows being transparent to wavelength of light with which the optical measurement is to be carried out so as to allow the light to interact with the fluid specimen in the cavities; and a transport mechanism to promote and complete flows of the fluid specimen from the recess to the plurality of cavities through the plurality of channels.
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公开(公告)号：US20180011335A1
公开(公告)日：2018-01-11
申请号：US15694682
申请日：2017-09-01
Applicant: Integrated Plasmonics Corporation
Inventor： Michael Yagoda SHAGAM , Robert Joseph WALTERS
IPC: G02B27/46 , B23K26/402 , G01N21/31 , G01N21/25 , B23K26/384 , C25D5/02 , C23C14/34 , B23K103/18
CPC classification number: G02B27/46 , B23K26/384 , B23K26/402 , B23K2103/18 , B23K2103/50 , C23C14/34 , C25D5/02 , G01N21/255 , G01N21/31 , G01N2201/0633 , G01N2201/068
Abstract: A spatial filter is made by forming a structure comprising a focusing element and an opaque surface, the opaque surface being disposed remotely from the focusing element in substantially the same plane as a focal plane of the focusing element; and by forming a pinhole in the opaque surface at or adjacent to a focal point of the focusing element by transmitting a substantially collimated laser beam through the focusing element so that a point optimally corresponding to the focal point is identified on the opaque surface and imperfection of the focusing element, if any, is reflected on the shape and position of the pinhole so formed.
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公开(公告)号：US09784986B2
公开(公告)日：2017-10-10
申请号：US14774990
申请日：2013-12-03
Applicant: Integrated Plasmonics Corporation
Inventor： Michael Yagoda Shagam , Robert Joseph Walters
IPC: G01N21/00 , G02B27/46 , G01N21/25 , G01N21/31 , B23K26/384 , B23K26/402 , C23C14/34 , C25D5/02 , B23K103/18
CPC classification number: G02B27/46 , B23K26/384 , B23K26/402 , B23K2103/18 , B23K2103/50 , C23C14/34 , C25D5/02 , G01N21/255 , G01N21/31 , G01N2201/0633 , G01N2201/068
Abstract: A spatial filter is made by forming a structure comprising a focusing element and an opaque surface, the opaque surface being disposed remotely from the focusing element in substantially the same plane as a focal plane of the focusing element; and by forming a pinhole in the opaque surface at or adjacent to a focal point of the focusing element by transmitting a substantially collimated laser beam through the focusing element so that a point optimally corresponding to the focal point is identified on the opaque surface and imperfection of the focusing element, if any, is reflected on the shape and position of the pinhole so formed.
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公开(公告)号：US09404797B2
公开(公告)日：2016-08-02
申请号：US14648843
申请日：2013-12-03
Applicant: Integrated Plasmonics Corporation
Inventor： Robert Joseph Walters
CPC classification number: G01J3/0229 , G01J3/0208 , G01J3/42 , G01N21/64 , G02B5/008
Abstract: A spectroscopic measurement system, which may utilize multiple plasmonic filters associated with a cuvette to monitor different wavelengths of light. The spectroscopic measurement system may measure absorbance and or fluorescence, and may have built-in low cost CMOS image sensor(s). Reagents and samples may be introduced to the cuvette from a fluidics manifold. Multiple sets of combined cuvettes, image sensors and plasmonic filters may utilize a single fluidics manifold for reagent and sample distribution.
Abstract translation: 一种光谱测量系统，其可以利用与比色皿相关联的多个等离子体激元滤波器来监测不同波长的光。 光谱测量系统可以测量吸光度和/或荧光，并且可以具有内置的低成本CMOS图像传感器。 试剂和样品可以从流体歧管引入试管。 多套组合的比色皿，图像传感器和等离子体激元过滤器可以利用单个流体歧管进行试剂和样品分布。
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Patent Agency Ranking
公开(公告)号：US20160018329A1
公开(公告)日：2016-01-21
申请号：US14775266
申请日：2013-12-03
Applicant: INTEGRATED PLASMONICS CORPORATION
Inventor： Robert Joseph WALTERS
IPC: G01N21/552
CPC classification number: G01N21/553
Abstract: A detection system includes a planar plasmonic element for analyzing an analyte, the plasmonic element having dielectric and metallic regions, the plasmonic element emitting light that carries detected information; and a planar two-dimensional image sensor positioned in non-parallel angled relationship with respect to a plane of the plasmonic element to enhance a spatial image resolution for the light that carries detected information with respect to at least a portion of the light.
Abstract translation: 检测系统包括用于分析分析物的平面等离子体元件，等离激元元件具有电介质和金属区域，等离子体元素发射携带检测信息的光; 以及平面二维图像传感器，其相对于等离子体元素元件的平面定位成非平行的角度关系，以增强携带相对于至少一部分光的检测信息的光的空间图像分辨率。
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公开(公告)号：US20140176939A1
公开(公告)日：2014-06-26
申请号：US14095971
申请日：2013-12-03
Applicant: Integrated Plasmonics Corporation
Inventor： Nilesh Dinbandhu Shah , Albert Jerwen Mach
IPC: G01N21/03
CPC classification number: G01N21/8483 , B01L3/502715 , B01L3/50273 , B01L2200/027 , B01L2300/043 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/0825 , B01L2300/0864 , B01L2300/0883 , B01L2300/1827 , B01L2400/0406 , B01L2400/0481 , B01L2400/049
Abstract: A microcuvette cartridge for optical measurement of a specimen includes: a substrate having a recess on an upper surface thereof to receive a fluid specimen therein, the substrate having a plurality of cavities therein to receive the fluid specimen transported from the recess, the substrate further defining a plurality of channels communicating with the recess and with the plurality of cavities, respectively, to transport the fluid specimen from the recess to the plurality of cavities, said substrate further having one or more of windows at positions corresponding to the plurality of cavities, the windows being transparent to wavelength of light with which the optical measurement is to be carried out so as to allow the light to interact with the fluid specimen in the cavities; and a transport mechanism to promote and complete flows of the fluid specimen from the recess to the plurality of cavities through the plurality of channels.
Abstract translation: 用于样本的光学测量的微型检测盒包括：在其上表面上具有凹部以接收其中的流体样本的衬底，所述衬底在其中具有多个空腔，以接收从凹部传送的流体样本，所述衬底进一步限定 分别与所述凹部和所述多个空腔连通的多个通道，用于将所述流体样本从所述凹部输送到所述多个空腔，所述基板还具有一个或多个窗口，所述窗口位于对应于所述多个空腔的位置， 窗口对于波长的光线是透明的，通过该窗口进行光学测量以允许光与空腔中的流体样本相互作用; 以及传送机构，以通过多个通道促进和完成流体样本从凹部到多个空腔的流动。
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公开(公告)号：US20140045730A1
公开(公告)日：2014-02-13
申请号：US14051114
申请日：2013-10-10
Applicant: INTEGRATED PLASMONICS CORPORATION
Inventor： Robert Joseph WALTERS
CPC classification number: C12Q1/6837 , G01N21/553 , G01N21/6428 , G01R3/00 , H01L31/02327
Abstract: An integrated plasmonic sensing device is monolithically integrated and provides marker-free detection (eliminating the need to use fluorescent or absorbing markers) and in-situ monitoring of conditions at each detection region. The integrated plasmonic sensing device includes a plasmonic backplane disposed on a monolithically integrated image sensor. One or more plasmonic scattering regions and one or more plasmonic via regions laterally offset from the plasmonic scattering regions are provided in the plasmonic sensing device. Guided plasmonic modes mediate power transfer through the plasmonic backplane to one or more underlying image sensor pixels.
Abstract translation: 集成的等离子体感测装置是单片集成的，并且提供无标记检测（消除了使用荧光或吸收标记的需要）和在每个检测区域的条件的原位监测。 集成等离子体感测装置包括设置在单片集成的图像传感器上的等离子体激元背板。 在等离子体激元感测装置中提供一个或多个等离子体激发散射区域和横向偏离等离子体激发散射区域的一个或多个等离子体通过区域。 引导等离激元模式通过等离子体激元背板将功率传递介导到一个或多个底层图像传感器像素。
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公开(公告)号：US08582108B2
公开(公告)日：2013-11-12
申请号：US13717201
申请日：2012-12-17
Applicant: Integrated Plasmonics Corporation
Inventor： Robert Joseph Walters
IPC: G01N21/55
CPC classification number: C12Q1/6837 , G01N21/553 , G01N21/6428 , G01R3/00 , H01L31/02327
Abstract: An integrated plasmonic sensing device is monolithically integrated and provides marker-free detection (eliminating the need to use fluorescent or absorbing markers) and in-situ monitoring of conditions at each detection region. The integrated plasmonic sensing device includes a plasmonic backplane disposed on a monolithically integrated image sensor. One or more plasmonic scattering regions and one or more plasmonic via regions laterally offset from the plasmonic scattering regions are provided in the plasmonic sensing device. Guided plasmonic modes mediate power transfer through the plasmonic backplane to one or more underlying image sensor pixels.
Abstract translation: 集成的等离子体感测装置是单片集成的，并且提供无标记检测（消除了使用荧光或吸收标记的需要）和在每个检测区域的条件的原位监测。 集成等离子体感测装置包括设置在单片集成的图像传感器上的等离子体激元背板。 在等离子体激元感测装置中提供一个或多个等离子体激发散射区域和横向偏离等离子体激发散射区域的一个或多个等离子体通过区域。 引导等离激元模式通过等离子体激元背板将功率传递介导到一个或多个底层图像传感器像素。
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公开(公告)号：US10241347B2
公开(公告)日：2019-03-26
申请号：US15694682
申请日：2017-09-01
Applicant: Integrated Plasmonics Corporation
Inventor： Michael Yagoda Shagam , Robert Joseph Walters
IPC: G01N21/00 , G02B27/46 , G01N21/25 , G01N21/31 , B23K26/384 , B23K26/402 , C23C14/34 , C25D5/02 , B23K103/18 , B23K103/00
Abstract: A spatial filter is made by forming a structure comprising a focusing element and an opaque surface, the opaque surface being disposed remotely from the focusing element in substantially the same plane as a focal plane of the focusing element; and by forming a pinhole in the opaque surface at or adjacent to a focal point of the focusing element by transmitting a substantially collimated laser beam through the focusing element so that a point optimally corresponding to the focal point is identified on the opaque surface and imperfection of the focusing element, if any, is reflected on the shape and position of the pinhole so formed.
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