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    Cold stress-responsive CRTintP gene and use thereof
    3.
    发明申请
    Cold stress-responsive CRTintP gene and use thereof 失效
    冷应激反应性CRTintP基因及其用途

    公开(公告)号：US20030200567A1

    公开(公告)日：2003-10-23

    申请号：US10304454

    申请日：2002-11-25

    Applicant: National Institute of Agrobiological Sciences ,  Japan Science and Technology Corporation

    Inventor： Setsuko Komatsu ,  Arun Sharma ,  Junji Hashimoto ,  Kengo Sakaguchi

    IPC: A01H001/00 ,  C07H021/04 ,  C12N015/82 ,  C12N005/04

    CPC classification number: C12N15/8273 ,  C07K14/415

    Abstract: An objective of the present invention is to isolate and identify a gene encoding the polypeptide that interacts with calreticulin (CRT), and to provide the gene and the use thereof. Specifically, an objective of the present invention is to provide the CRTintP gene, the transformed plants comprising the CRTintP gene, and a method of producing these transformed plants. The present inventors successfully detected a group of CRT-interacting genes using the yeast two-hybrid method. As a result, the present inventors detected the polynucleotide encoding the CRT-interacting polypeptide (named as CRTintP). Furthermore, the present inventors isolated the full-length cDNA encoding the CRTintP and revealed that the gene encoding the cDNA was novel. It was found that the expression of the CRT and CRTintP genes was significantly increased following application of cold stress in rice leaves.

    Abstract translation: 本发明的目的是分离和鉴定编码与钙网蛋白（CRT）相互作用的多肽的基因，并提供该基因及其用途。 具体地，本发明的目的是提供CRTintP基因，包含CRTintP基因的转化植物以及这些转化植物的生产方法。 本发明人使用酵母双杂交方法成功地检测了一组CRT相互作用的基因。 结果，本发明人检测到编码CRT相互作用多肽（命名为CRTintP）的多核苷酸。 此外，本发明人分离了编码CRTintP的全长cDNA，并显示编码cDNA的基因是新的。 发现应用冷胁迫后，CRT和CRTintP基因的表达显着增加。

    Development of method for screening physiologically active pyrrole imidazole derivative
    4.
    发明申请
    Development of method for screening physiologically active pyrrole imidazole derivative 失效
    开发用于筛选生理活性吡咯咪唑衍生物的方法

    公开(公告)号：US20030099998A1

    公开(公告)日：2003-05-29

    申请号：US10285030

    申请日：2002-11-01

    Applicant: Japan Science and Technology Corporation

    Inventor： Hiroshi Sugiyama ,  Isao Saito ,  Hirokazu Iida

    IPC: C12Q001/68 ,  C07H021/04

    CPC classification number: G01N33/5011

    Abstract: A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.

    Abstract translation: 通过使用人造化学物质筛选片段A（化学物质A）对含有DNA或RNA的物质（例如细胞）的影响的方法。 即，通过使用能够识别DNA碱基序列的由以下通式（I）表示的一种或多种化学物质来检测或鉴定含有DNA或RNA的物质上的化学物质A的功能的方法; 一套工具; 和其中使用的板：B-L-A（I）其中B表示含有能够识别DNA碱基序列的非天然碱基的化学结构; A表示与DNA相互作用的化学结构; L表示连接物，化学结构A和B可以连接在一起。

    Placental organic anion transporter and gene thereof
    5.
    发明申请
    Placental organic anion transporter and gene thereof 有权
    胎盘有机阴离子转运蛋白及其基因

    公开(公告)号：US20030096947A1

    公开(公告)日：2003-05-22

    申请号：US10339513

    申请日：2003-01-09

    Applicant: Japan Science and Technology Corporation, Japan

    Inventor： Hitoshi Endou ,  Takashi Sekine ,  Seok Ho Cha

    IPC: C07K014/47 ,  C12Q001/68 ,  C07H021/04 ,  C12P021/02 ,  C12N005/06

    CPC classification number: C07K14/47 ,  C07K14/705 ,  C12Q1/6876 ,  C12Q2600/158

    Abstract: A novel organic anion transporter gene participating in organic anion transport in the placenta; and an organic anion transporter which is a polypeptide encoded by the gene. A placental organic anion transporter OAT4, more particularly, a placental organic anion transporter OAT4 having the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence derived therefrom by deletion, substitution or addition of a part of the amino acids thereof. A nucleic acid (preferably DNA) having a base sequence encoding the placental organic anion transporter OAT4 or a base sequence hybridizable therewith under stringent conditions.

    Abstract translation: 参与胎盘中有机阴离子转运的新型有机阴离子转运蛋白基因; 和由该基因编码的多肽的有机阴离子转运蛋白。 胎盘有机阴离子转运蛋白OAT4，更特别是具有由SEQ ID NO：2表示的氨基酸序列的胎盘有机阴离子转运蛋白OAT4或其部分氨基酸的缺失，取代或添加导致的氨基酸序列。 具有编码胎盘有机阴离子转运蛋白OAT4的碱基序列或在严格条件下可与其杂交的碱基序列的核酸（优选DNA）。

    Microscope
    6.
    发明申请
    Microscope 有权
    显微镜

    公开(公告)号：US20020167724A1

    公开(公告)日：2002-11-14

    申请号：US10103190

    申请日：2002-03-21

    Applicant: JAPAN SCIENCE AND TECHNOLOGY CORPORATION

    Inventor： Yoshinori Iketaki ,  Masaaki Fujii ,  Takashige Omatsu ,  Kimihisa Yamamoto ,  Toshio Suzuki

    IPC: G02B001/00

    CPC classification number: G02B21/06

    Abstract: A microscope includes a first light source to emit a first light to excite a molecule of a sample to a higher energy level vibration state which belongs to a lowest energy level electron state from the ground state, a second light source to emit a second light source to excite the molecule to a higher energy level quantum state from the higher energy vibration state, an optical system to overlap the first light and the second light partially on the sample, and an optical detector to detect a given fluorescence from the irradiated region of the first light and the second light on the sample.

    Abstract translation: 显微镜包括：第一光源，用于发射第一光以将样品的分子激发到属于基本状态的最低能量级电子态的较高能级振动状态，第二光源发射第二光源 从更高的能量振动状态激发分子到更高的能量级量子态，光学系统将部分地与样品上的第一光和第二光重叠，以及光学检测器，用于检测来自辐射源的照射区域的给定荧光 样品上的第一个光和第二个光。

    Polyester synthase and a gene coding for the same
    7.
    发明申请
    Polyester synthase and a gene coding for the same 失效
    聚酯合酶和编码相同的基因

    公开(公告)号：US20020086377A1

    公开(公告)日：2002-07-04

    申请号：US09989786

    申请日：2001-11-19

    Applicant: Japan Science and Technology Corporation

    Inventor： Yoshiharu Doi ,  Toshiaki Fukui ,  Hiromi Matsusaki

    IPC: C12P007/62 ,  C07H021/04 ,  C12N009/00 ,  C12N009/16 ,  C12P021/02 ,  C12N005/06

    CPC classification number: C12N9/88

    Abstract: The present invention relates to a polypeptide comprising the amino acid sequence of SEQ ID NO: 1 or a sequence where in said amino acid sequence, one or more amino acids are deleted, replaced or added, said polypeptide having polyester synthase activity; a polyester synthase gene comprising DNA coding for said polypeptide; a recombinant vector comprising the gene; and a transformant transformed with the recombinant vector.

    Abstract translation: 本发明涉及包含SEQ ID NO：1的氨基酸序列的多肽或其中在所述氨基酸序列中缺失，置换或添加一个或多个氨基酸的所述多肽具有聚酯合酶活性的序列; 包含编码所述多肽的DNA的聚酯合酶基因; 包含该基因的重组载体; 和用重组载体转化的转化体。

    Photo-induced phase transition organic material
    8.
    发明申请
    Photo-induced phase transition organic material 失效
    光诱导相变有机物质

    公开(公告)号：US20020007072A1

    公开(公告)日：2002-01-17

    申请号：US09927931

    申请日：2001-08-13

    Applicant: JAPAN SCIENCE AND TECHNOLOGY CORPORATION

    Inventor： Masahiro Irie

    IPC: C07D43/02 ,  A23L001/00

    CPC classification number: G02F1/0126 ,  C07D333/18 ,  C09K9/02 ,  G02F1/0009

    Abstract: A photo-induced phase transition organic material is composed of a diheteroarylethene-based compound within which the photo-chromic reaction occurs in the crystalline state. The diheteroarylethene-based compound of the present invention reversibly changes in color with light irradiation and also changes in phase from the open-ring form in the crystalline state to the closed-ring form in the crystalline state, or from the closed-ring form in the crystalline state to the open-ring form in the crystalline state via the liquid state, and can be applicable to optical recording media, display panels, sensors, optical switch devices and the like, by taking advantages of its variations in color with light irradiation and also its changes in physical property, such as the refractive index and the permeability, with its changes in phase.

    Abstract translation: 光诱导的相变有机材料由二元基乙烯基化合物组成，其中光致铬反应在其结晶状态下发生。 本发明的基于二杂芳基乙烯的化合物随着光照射而可逆地改变颜色，并且在结晶状态下也可以从结晶状态的开环形式到结晶状态的闭环形式，或者从闭环形式 通过液体状态处于结晶态的开环形状的结晶状态，并且可以通过利用其在光照射下的颜色变化的优点而适用于光学记录介质，显示面板，传感器，光学开关装置等 以及物理性质的变化，如折射率和渗透率，其相位变化。

    Micro electron gun of quantum size effect type and flat display using such electron guns as well as methods of their manufacture
    10.
    发明申请
    Micro electron gun of quantum size effect type and flat display using such electron guns as well as methods of their manufacture 失效
    量子尺寸效应型微电子枪和使用这种电子枪的平面显示器及其制造方法

    公开(公告)号：US20040055530A1

    公开(公告)日：2004-03-25

    申请号：US10667517

    申请日：2003-09-23

    Applicant: JAPAN SCIENCE AND TECHNOLOGY CORPORATION

    Inventor： Shunri Oda ,  Xinwei Zhao ,  Katsuhiko Nishiguchi

    IPC: C30B023/00 ,  H01L021/20 ,  H01L021/00 ,  H01L021/36

    CPC classification number: B82Y10/00 ,  H01J1/312 ,  H01J9/027

    Abstract: A micro electron gun that is capable of extracting electrons from a semiconductor utilizing a quantum size effect and that can be mounted individually for each of pixels is disclosed, as well as a picture display apparatus using such electron guns which is high in quantum efficiency, of high brightness and thin, as well as methods of manufacture thereof. Conduction electrons from a n-type semiconductor substrate (2) are accelerated under an electric field through a layer or layers (4) of quantum size effect micro particles (3) formed on surfaces of the n-type semiconductor substrate (2) and passed therethrough without undergoing phonon scattering, so that they when arriving at an electrode (5) may possess an amount of energy not less than the work function of the electrode (5) and are thus allowed to spring out into a vacuum. Such a quantum size effect micro particle (3) comprises a micro particle of a single crystal semiconductor in a nanometer order having electron energy levels made so discrete that no phonon scattering is brought about, and on its surface area an insulator so thin that an electron is capable of tunneling therethrough.

    Abstract translation: 公开了能够利用量子尺寸效应从半导体中提取电子并且可以针对每个像素单独安装的微电子枪，以及使用这样的量子效率高的电子枪的图像显示装置， 高亮度和薄，以及其制造方法。 来自n型半导体衬底（2）的传导电子在电场下通过形成在n型半导体衬底（2）的表面上的量子尺寸效应微粒（3）的层（4）加速并通过 从而使其在到达电极（5）时可能具有不小于电极（5）的功函数的能量，并因此允许弹出到真空中。 这样的量子尺寸效应微粒（3）包括纳米级的单晶半导体微粒子，其具有使得离散的电子能级不能产生声子散射，并且在其表面积上具有如此薄的绝缘体 能穿过隧道。

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