公开(公告)号：US07776057B2

公开(公告)日：2010-08-17

申请号：US10992228

申请日：2004-11-19

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

IPC: A61B17/04

CPC classification number: A61B17/0057 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/0686 ,  A61B17/122 ,  A61B17/1285 ,  A61B17/285 ,  A61B17/29 ,  A61B2017/00292 ,  A61B2017/00296 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2017/3488 ,  A61B2090/065 ,  A61M25/0133 ,  A61M25/0147

Abstract: A method includes advancing an apparatus having an elongated member transorally into the stomach. The apparatus includes a distal end effector having first and second members configured to engage tissue. The first and second members are movable relatively toward one another generally in a first plane. The method includes moving the distal end effector relative to the elongated member in the first plane such that the distal end effector is retroflexed out of alignment with the elongated member to position the first and second members for engagement with the tissue. At least one of the first and second members carries a fixation device for fixing engaged portions of tissue together.

Abstract translation: 一种方法包括将具有细长构件的装置经腹进入胃。 该装置包括远端执行器，其具有构造成接合组织的第一和第二构件。 第一和第二构件通常在第一平面中可相对于彼此移动。 该方法包括在第一平面中使远端执行器相对于细长构件移动，使得远端执行器被逆转而不与细长构件对准，以定位第一和第二构件以与组织接合。 第一和第二构件中的至少一个承载用于将组织的接合部分固定在一起的固定装置。

公开(公告)号：US06835200B2

公开(公告)日：2004-12-28

申请号：US10197574

申请日：2002-07-18

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

IPC: A61B1708

CPC classification number: A61B17/0057 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/0686 ,  A61B17/122 ,  A61B17/1285 ,  A61B17/285 ,  A61B17/29 ,  A61B2017/00292 ,  A61B2017/00296 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2017/3488 ,  A61B2090/065 ,  A61M25/0133 ,  A61M25/0147

Abstract: A method includes advancing an apparatus having an elongated member transorally into the stomach. The apparatus includes a distal end effector having first and second members configured to engage tissue. The first and second members are movable relatively toward one another generally in a first plane. The method includes moving the distal end effector relative to the elongated member in the first plane such that the distal end effector is retroflexed out of alignment with the elongated member to position the first and second members for engagement with the tissue. At least one of the first and second members carries a fixation device for fixing engaged portions of tissue together.

Abstract translation: 一种方法包括将具有细长构件的装置经腹进入胃。 该装置包括远端执行器，其具有构造成接合组织的第一和第二构件。 第一和第二构件通常在第一平面中可相对于彼此移动。 该方法包括在第一平面中使远端执行器相对于细长构件移动，使得远端执行器被逆转而不与细长构件对准，以定位第一和第二构件以与组织接合。 第一和第二构件中的至少一个承载用于将组织的接合部分固定在一起的固定装置。

公开(公告)号：US06821285B2

公开(公告)日：2004-11-23

申请号：US09859579

申请日：2001-05-18

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

IPC: A61B1708

CPC classification number: A61B17/0686 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00296 ,  A61B2017/00314 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2090/065 ,  A61M25/0147

Abstract: A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.

公开(公告)号：US08821527B2

公开(公告)日：2014-09-02

申请号：US13602747

申请日：2012-09-04

Applicant: Robert C. Farnan ,  Arielle Drummond ,  Jerry Brightbill ,  Timothy Walter Robinson ,  Richard Wisdom ,  Jonathan O'Keefe ,  Richard Abraham ,  Sarah Kostanski ,  Bryan Fritz

Inventor： Robert C. Farnan ,  Arielle Drummond ,  Jerry Brightbill ,  Timothy Walter Robinson ,  Richard Wisdom ,  Jonathan O'Keefe ,  Richard Abraham ,  Sarah Kostanski ,  Bryan Fritz

IPC: A61B17/00 ,  A61M5/32

CPC classification number: A61M1/1008 ,  A61B17/11 ,  A61B17/32 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61M1/12 ,  A61M1/122

Abstract: A surgical cannula system. The surgical cannula system includes a cannula having a proximal end, a distal end, and a lumen extending therebetween. A tissue attachment ring, being configured to be coupled to a biological tissue, includes a lumen extending therethrough. A locking mechanism has a first locking state, in which the cannula is configured to move with respect to the tissue attachment ring, and a second locking state, in which movement of the cannula with respect to the tissue attachment ring is resisted.

Abstract translation: 手术插管系统。 外科插管系统包括具有近端，远端和在其间延伸的腔的套管。 被配置为联接到生物组织的组织附接环包括延伸穿过其中的内腔。 锁定机构具有第一锁定状态，其中套管构造成相对于组织附接环移动，并且第二锁定状态，其中套管相对于组织附接环的运动被抵抗。

公开(公告)号：US08277468B2

公开(公告)日：2012-10-02

申请号：US12953625

申请日：2010-11-24

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos G. Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Piucci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos G. Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Piucci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randal B. Chinnock

IPC: A61B17/08

CPC classification number: A61B17/0686 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00296 ,  A61B2017/00314 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2090/065 ,  A61M25/0147

Abstract: A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.

Abstract translation: 用于接合组织的医疗器械包括柔性轴，在轴的远端部分处的组织穿刺线圈和定位在轴上并且在远侧方向偏置的组织稳定器，使得当组织穿刺线圈进入组织时，组织稳定器 被推靠在组织的表面上。 用于重构组织的医疗器械包括限定腔室壳体致动控制器的柔性轴和具有密封部分的远端致动组件，所述密封部分构造成基本上密封轴腔与身体液体的接触。 盒组件包括构造成用于可释放地附接到医疗器械的第一和第二构件，以及保持器，构造成容纳第一和第二构件并且在第一和第二构件附接到医疗装置的作用下从第一构件和第二构件释放 仪器。

公开(公告)号：US07722633B2

公开(公告)日：2010-05-25

申请号：US10819957

申请日：2004-04-08

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

IPC: A61B17/08 ,  A61B17/04

CPC classification number: A61B17/0686 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00296 ,  A61B2017/00314 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2090/065 ,  A61M25/0147

Abstract: A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.

Abstract translation: 用于接合组织的医疗器械包括柔性轴，在轴的远端部分处的组织穿刺线圈和定位在轴上并且在远侧方向偏置的组织稳定器，使得当组织穿刺线圈进入组织时，组织稳定器 被推靠在组织的表面上。 用于重构组织的医疗器械包括限定腔室壳体致动控制器的柔性轴和具有密封部分的远端致动组件，所述密封部分构造成基本上密封轴腔与身体液体的接触。 盒组件包括构造成用于可释放地附接到医疗器械的第一和第二构件，以及保持器，构造成容纳第一和第二构件并且在第一和第二构件附接到医疗装置的作用下从第一构件和第二构件释放 仪器。

公开(公告)号：US07713277B2

公开(公告)日：2010-05-11

申请号：US10828469

申请日：2004-04-21

Applicant: Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C. Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

IPC: A61B17/08

CPC classification number: A61B17/0686 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00296 ,  A61B2017/00314 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2090/065 ,  A61M25/0147

Abstract: A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.

公开(公告)号：US5769091A

公开(公告)日：1998-06-23

申请号：US599636

申请日：1996-02-09

Applicant: John G. Simon ,  Paul D. McLaughlin ,  Leo C. Felice ,  Sharad Joshi ,  Azhar Syed ,  Richelle Tartacower ,  Jonathan O'Keefe

Inventor： John G. Simon ,  Paul D. McLaughlin ,  Leo C. Felice ,  Sharad Joshi ,  Azhar Syed ,  Richelle Tartacower ,  Jonathan O'Keefe

IPC: A61F5/37 ,  A61F2/00 ,  A61F5/48 ,  A61M31/00

CPC classification number: A61F2/0013 ,  A61F2/0009 ,  A61F2/005 ,  A61F5/48 ,  A61M31/00 ,  Y10S128/25

Abstract: A novel urethral plug having adhesive thereon, wherein the adhesive seals the plug against the tissues surrounding the meatus and/or urethra, thereby arresting movement of the plug while it functions in the urethra to block the flow of urine. The urethral plug comprises a hollow or solid body which is of a sufficient length and diameter to occlude the urethra. In one embodiment, adhesive is disposed on the meatal plate of the plug so as to secure the plug against the tissues surrounding the urethral meatus. In a second embodiment, adhesive is disposed on the body of the plug so as to seal the plug against the urethral wall. In a third embodiment, the adhesive is disposed on a portion of the meatal plate so as to seal the plug against the tissues surrounding the urethral meatus. The adhesive seals the urethral plug in place until the user wishes to void, at which time, the seal may be broken by exerting a pulling force on the plug.

Abstract translation: 一种在其上具有粘合剂的新型尿道塞，其中所述粘合剂将塞子密封在围绕牙槽孔和/或尿道的组织上，从而阻止塞子在尿道中起作用以阻止尿液流动。 尿道塞包括中空或实体，其具有足够的长度和直径以阻塞尿道。 在一个实施例中，将粘合剂设置在插塞的肉片上，以将塞子固定在尿道口周围的组织上。 在第二实施例中，粘合剂设置在塞子的主体上，以将塞子密封抵靠尿道壁。 在第三实施例中，粘合剂设置在肉片的一部分上，以将塞子密封在围绕尿道口的组织上。 粘合剂将尿道塞子密封到位，直到使用者希望无效，此时可能通过在塞子上施加拉力来破坏密封。

公开(公告)号：US20180228557A1

公开(公告)日：2018-08-16

申请号：US15567109

申请日：2016-04-20

Applicant: Ian J. Darisse ,  Gabriel A. Johnston ,  Richard Walker, Jr. ,  Leland Witherspoon ,  David Warnock ,  Thomas Calef ,  Eric Daley ,  Stephen Tully ,  Amoz Cruz ,  Jonathan O'Keefe ,  JEffrey Cerier ,  Emily Triggs ,  Simon Grover ,  Andras Pungor ,  J. Christopher Flaherty ,  R. Maxwell Flaherty

Inventor： Ian J. Darisse ,  Gabriel A. Johnston ,  Richard Walker, Jr. ,  Leland Witherspoon ,  David Warnock ,  Thomas Calef ,  Eric Daley ,  Stephen Tully ,  Amoz Cruz ,  Jonathan O'Keefe ,  JEffrey Cerier ,  Emily Triggs ,  Simon Grover ,  Andras Pungor ,  J. Christopher Flaherty ,  R. Maxwell Flaherty

IPC: A61B34/30 ,  A61B1/05 ,  A61B1/12 ,  A61B50/13 ,  A61B1/00 ,  A61B1/005 ,  A61B1/008

CPC classification number: A61B34/30 ,  A61B1/00009 ,  A61B1/00055 ,  A61B1/00114 ,  A61B1/00117 ,  A61B1/00149 ,  A61B1/00158 ,  A61B1/0016 ,  A61B1/005 ,  A61B1/0057 ,  A61B1/008 ,  A61B1/018 ,  A61B1/05 ,  A61B1/0646 ,  A61B1/0676 ,  A61B1/0684 ,  A61B1/07 ,  A61B1/126 ,  A61B1/32 ,  A61B10/02 ,  A61B17/3201 ,  A61B46/20 ,  A61B50/13 ,  A61B2034/301 ,  A61B2034/306 ,  A61F5/005 ,  A61M5/14 ,  A61N5/1007 ,  H01H47/002 ,  Y10S901/41 ,  Y10S901/47

Abstract: A system for performing a medical procedure comprises a first assembly and a second assembly. The first assembly comprises an articulating probe assembly and a first housing. The articulating probe assembly comprises an outer probe and an inner probe. The outer probe comprises: multiple articulating outer links and a first connector. The inner probe comprises multiple articulating inner links and a second connector. The first housing comprises: a proximal portion; a distal portion; and an opening positioned in the first housing distal portion. The articulating probe is constructed and arranged to pass through the first housing opening. The second assembly comprises: a first carriage constructed and arranged to operably engage the first connector of the outer probe; a second carriage constructed and arranged to operably engage the second connector of the inner probe; a dual linear drive assembly configured to independently translate the first carriage and the second carriage; and a second housing comprising a proximal portion and a distal portion. The first assembly is constructed and arranged to operably attach to the second assembly. Methods of performing a medical procedure are also described.

公开(公告)号：US07857823B2

公开(公告)日：2010-12-28

申请号：US10819996

申请日：2004-04-08

Applicant: Michael D. Laufer ,  Jeffrey C Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

Inventor： Michael D. Laufer ,  Jeffrey C Cerier ,  Amos Cruz ,  Jonathan O'Keefe ,  Richard Andrews ,  Ram Chuttani ,  Vincent A. Puicci, Jr. ,  Michael Barenboym ,  Neal H. Marshall ,  Randall B. Chinnock

IPC: A61B17/08

CPC classification number: A61B17/0686 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0401 ,  A61B17/0467 ,  A61B17/0482 ,  A61B17/0485 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00296 ,  A61B2017/00314 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00827 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/061 ,  A61B2017/2905 ,  A61B2017/2915 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/308 ,  A61B2090/065 ,  A61M25/0147

Abstract: A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.