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13 条记录 (耗时 0.02 秒)

    Precoated polymeric prosthesis and process for making same
    1.
    发明授权
    Precoated polymeric prosthesis and process for making same 失效
    预涂聚合物假体及其制备方法

    公开(公告)号：US06558428B2

    公开(公告)日：2003-05-06

    申请号：US09772795

    申请日：2001-01-30

    申请人： Joon B. Park

    发明人： Joon B. Park

    IPC分类号： A61F228

    CPC分类号： C09D133/12 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/38 ,  A61F2/3859 ,  A61F2/389 ,  A61F2002/30014 ,  A61F2002/30153 ,  A61F2002/30878 ,  A61F2002/30929 ,  A61F2002/30934 ,  A61F2002/30968 ,  A61F2002/3611 ,  A61F2002/365 ,  A61F2002/4631 ,  A61F2230/0019 ,  A61F2250/0018 ,  A61F2310/00011 ,  A61F2310/00952 ,  A61L27/26 ,  A61L27/34 ,  A61L2420/02 ,  C08L23/06 ,  Y10S623/923 ,  C08L33/12 ,  C08L2666/04

    摘要： The present invention is directed to a polymeric prosthesis precoated with a bone cement compatible polymer. The bone cement compatible polymer coating, is provided by an activated powder mixture of polymethyl methacrylate and ultra high molecular weight polyethylene which is bonded to the outer surface of the prosthesis by sintering. Once bonded to a polymeric prosthesis in accordance with the present invention, the precoat strengthens the interface between a bone cement and a prosthesis when the prosthesis is later implanted. The inner layer of the prosthesis may be provided of cross-linked UHMWPE powder sintered with virgin UHMWPE powder or fibers to provide a intermediate layer(s) of the coating present on the prosthesis. The precoat also decreases the likelihood that the prosthesis will loosen and break away from the cement over time. The polymeric implant product of the present invention is particularly well suited for use as an acetabular cup or a tibia plateau in replacing hip joints and knee joints respectively.

    摘要翻译： 本发明涉及预先涂覆有骨水泥相容性聚合物的聚合物假体。 骨水泥相容的聚合物涂层由聚甲基丙烯酸甲酯和超高分子量聚乙烯的活化粉末混合物提供，其通过烧结结合到假体的外表面。 一旦结合到根据本发明的聚合物假体，当稍后植入假体时，预涂层加强骨水泥和假体之间的界面。 假体的内层可以提供与原始UHMWPE粉末或纤维烧结的交联UHMWPE粉末，以提供假体上存在的涂层的中间层。 预涂也降低假体随着时间的推移松动和脱离水泥的可能性。 本发明的聚合物植入物特别适合用作分别替代髋关节和膝关节的髋臼杯或胫骨平台。

    Non-stress-shielding bone fracture healing device
    7.
    发明授权
    Non-stress-shielding bone fracture healing device 失效
    非应力屏蔽骨折愈合装置

    公开(公告)号：US5057111A

    公开(公告)日：1991-10-15

    申请号：US116497

    申请日：1987-11-04

    申请人： Joon B. Park

    发明人： Joon B. Park

    IPC分类号： A61B17/00 ,  A61B17/80

    CPC分类号： A61B17/8047 ,  A61B2017/00004

    摘要： A non-stress-shielding bone fracture healing compression device is to be used with screws, pins or nails for attaching the device to bone tissue. A rigid plate has at least two openings therethrough for purposes of attaching the plate to the bone with screws, pins or nails. At least one of the openings is a relaxation opening that has an opening surface shaped at least in part as a truncated spherical section and has an entrance hole through the top of the plate and an exit hole through the bottom of the plate. The polymer member is shaped to conform to the opening surface and to form circular entrance and exit holes concentric with the respective relaxation opening surface entrance and exit holes. The polymer member can be either resorbable material or viscoelastic material and can be configured to cover either all or less than all of the opening surface of the relaxation opening. When the plate is in use, the resorbable material is absorbed into the body to lessen contact between the pin, for example, and the plate, thereby reducing the load carried by the plate and pin and increasing the load carried by the bone attached to the plate and pin. When viscoelastic material is used, the stress gradually causes this material to creep away from contact with the pin, for example, and the load carried by the plate and pin is reduced while the load carried by the bone is increased.

    摘要翻译： 非应力屏蔽骨折愈合压缩装置用于将装置连接到骨组织上的螺钉，销钉或钉子。 刚性板具有穿过其中的至少两个开口，用于通过螺钉，销钉或钉子将板附接到骨头。 开口中的至少一个是松弛开口，其具有至少部分成形为截顶球形的开口表面，并且具有穿过板的顶部的入口孔和穿过板的底部的出口孔。 聚合物构件被成形为符合开口表面并且形成与相应的松弛开口表面入口和出口孔同心的圆形入口和出口孔。 聚合物构件可以是可再吸收材料或粘弹性材料，并且可以被构造成覆盖松弛开口的全部或者小于全部的开口表面。 当使用该板时，可再吸收的材料被吸收到体内以减小例如销和板之间的接触，从而减少由板和销承载的负载，并且增加由附着到板上的骨承载的负载 板和针。 当使用粘弹性材料时，应力逐渐导致该材料与销的接触脱离，并且由骨承载的负载增加时，由板和销承载的载荷减小。

    Surgically implantable spinal correction system
    8.
    发明授权
    Surgically implantable spinal correction system 失效
    手术植入式脊柱矫正系统

    公开(公告)号：US4836196A

    公开(公告)日：1989-06-06

    申请号：US142493

    申请日：1988-01-11

    申请人： Joon B. Park ,  James N. Weinstein ,  Vijay K. Goel

    发明人： Joon B. Park ,  James N. Weinstein ,  Vijay K. Goel

    IPC分类号： A61B17/70 ,  A61B17/86

    CPC分类号： A61B17/701 ,  A61B17/7007 ,  A61B17/7062 ,  A61B17/8695 ,  Y10S606/91

    摘要： An apparatus for connecting a structure with a vertebral body of a spinal column and for transmitting a load between the structure and the vertebral body. The apparatus includes a fastener with a threaded portion for threaded engagement with a surface defining an opening in the vertebral body to connect the vertebral body with the structure. A spacer is adapted to be located between the fastener and the structure for transmitting load therebetween. The spacer is made of a material which plastically deforms as a function of time and load applied thereto to decrease the load transmitted between the vertebral body and the structure.

    摘要翻译： 一种用于将结构与脊柱的椎体连接并用于在结构和椎体之间传递负载的装置。 该装置包括具有螺纹部分的紧固件，用于与限定椎体内的开口的表面螺纹接合，以将椎体与结构连接。 间隔件适于位于紧固件和用于在它们之间传递载荷的结构之间。 间隔件是由施加于其上的时间和负载的函数塑性变形的材料制成的，以减小在椎体和结构之间传递的载荷。

    Bone cement syringe
    9.
    发明授权
    Bone cement syringe 失效
    骨水泥注射器

    公开(公告)号：US4751921A

    公开(公告)日：1988-06-21

    申请号：US789782

    申请日：1985-10-21

    申请人： Joon B. Park

    发明人： Joon B. Park

    IPC分类号： A61F2/46 ,  A61F5/04

    CPC分类号： A61B17/8825 ,  A61B17/8827

    摘要： A pair of screens in the barrel of a bone cement syringe improves the strength of the bone cement by breaking large bubbles into many small bubbles.

    摘要翻译： 骨水泥注射器的桶中的一对筛子通过将大气泡破坏成许多小气泡来改善骨水泥的强度。

    In situ controlled release drug delivery system
    10.
    发明授权
    In situ controlled release drug delivery system 有权
    原位控释药物输送系统

    公开(公告)号：US08940311B2

    公开(公告)日：2015-01-27

    申请号：US11256416

    申请日：2005-10-21

    申请人： Tae-Hong Lim ,  Joon B. Park ,  Jin Whan Lee

    发明人： Tae-Hong Lim ,  Joon B. Park ,  Jin Whan Lee

    IPC分类号： A61K9/00 ,  A61K9/50 ,  A61K9/16 ,  A61K47/34

    CPC分类号： A61K47/34 ,  A61K9/0019 ,  A61K9/0024 ,  A61K9/06 ,  A61K9/1647 ,  A61K9/5031 ,  A61K9/5084 ,  A61K31/137 ,  A61K31/192 ,  A61K31/439 ,  A61K31/44 ,  A61K31/445 ,  A61K31/4741 ,  A61K31/485 ,  A61K31/55 ,  A61K31/60 ,  A61K31/606 ,  A61K31/655 ,  A61K36/66 ,  A61K45/06 ,  A61K47/36

    摘要： A system is described for long-term controlled release delivery of a drug or a therapeutic agent. According to the invention, one or more drugs or therapeutic agents contained in microspheres are mixed with a temperature sensitive hydrogel which is then introduced directly to the desired situs of the drug or therapeutic agent. The temperature sensitive hydrogel may also contain a drug or a therapeutic agent, for example, a pain relieving drug, for a short-term controlled release. The temperature sensitive hydrogel is in liquid state at room temperature, but upon injection, shortly becomes gelatinous. This system is particularly suitable for treatment of diseases, disorders, or conditions, for example, tumors, discogenic back pain, or arthritis, warranting localized administration of a drug or a therapeutic agent. In addition, the specification provides a method for production of a drug- or therapeutic agent-containing microspheres.

    摘要翻译： 描述了用于药物或治疗剂的长期控制释放递送的系统。 根据本发明，将微球中包含的一种或多种药物或治疗剂与温度敏感的水凝胶混合，然后将其直接引入药物或治疗剂的所需位置。 对于短期控释，温敏水凝胶也可含有药物或治疗剂，例如止痛药。 温度敏感的水凝胶在室温下处于液态，但注射后不久便变成凝胶状。 该系统特别适用于治疗疾病，病症或病症，例如肿瘤，椎间盘背痛或关节炎，需要局部施用药物或治疗剂。 此外，本说明书提供了制备含药物或治疗剂的微球体的方法。