公开(公告)号：US08383187B2

公开(公告)日：2013-02-26

申请号：US12688023

申请日：2010-01-15

申请人： Kori Rivard ,  Jeff Rybolt

发明人： Kori Rivard ,  Jeff Rybolt

IPC分类号： A61F2/02 ,  A61F2/28 ,  A61L27/30 ,  B05D3/00

CPC分类号： B22F3/1121 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2002/3092 ,  A61F2310/00179 ,  A61F2310/00401 ,  A61F2310/00407 ,  A61F2310/00425 ,  A61F2310/00431 ,  A61F2310/00449 ,  A61F2310/00461 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61L27/306 ,  A61L27/56 ,  B22F3/1134 ,  B22F7/002 ,  C23C24/087 ,  Y10T428/24413

摘要： The present invention provides a method for processing a green body comprising a powder mixture in which a metal powder and a space filler assume respective positions, comprising applying a material that comprises aspherical metallic particles to at least one surface of the green body, thereby forming a coating on the green body. The present invention also provides implants that are produced in accordance with such method.

摘要翻译： 本发明提供了一种加工生坯体的方法，其包括粉末混合物，其中金属粉末和空间填充物呈现各自的位置，包括将包含非球面金属颗粒的材料施加到生坯的至少一个表面，由此形成 涂在绿色的身上。 本发明还提供根据这种方法生产的植入物。

公开(公告)号：US20080300682A1

公开(公告)日：2008-12-04

申请号：US11961382

申请日：2007-12-20

申请人： Kori Rivard ,  Bernice Aboud

发明人： Kori Rivard ,  Bernice Aboud

IPC分类号： A61F2/02 ,  A61B19/00

CPC分类号： A61F2/30767 ,  A61F2/3094 ,  A61F2/36 ,  A61F2/3662 ,  A61F2002/30011 ,  A61F2002/30929 ,  A61F2002/30968 ,  A61F2002/3631 ,  A61F2250/0023 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00131 ,  A61F2310/00407 ,  A61F2310/00413 ,  A61F2310/00449 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61L27/306 ,  A61L27/56 ,  B22F7/004 ,  B22F2998/00 ,  C23C24/08 ,  B22F1/0007 ,  B22F1/0048

摘要： The present invention concerns articles having an outer surface that bears at least two layers of metal particles, wherein the at least two layers comprise an outermost layer and an intermediate layer; the outermost layer consisting essentially of aspherical metallic particles having a mean particle size of 50 to 500 microns; and the intermediate layer consisting essentially of substantially spherical metallic particles having a mean particle size of from 50 to 500 microns. In some embodiments, the outer surface has a volume porosity of between about 20% to about 80%.

摘要翻译： 本发明涉及具有至少两层金属颗粒的外表面的制品，其中至少两层包括最外层和中间层; 最外层基本上由平均粒径为50至500微米的非球面金属颗粒组成; 并且中间层基本上由平均粒度为50至500微米的基本上球形的金属颗粒组成。 在一些实施方案中，外表面的体积孔隙率为约20％至约80％。

公开(公告)号：US20180353635A1

公开(公告)日：2018-12-13

申请号：US16001964

申请日：2018-06-07

申请人： IMT Masken und Teilungen AG

发明人： Goetz Thorwarth

IPC分类号： A61L2/28 ,  A61L2/07 ,  A61L31/08 ,  A61L27/30

CPC分类号： A61L2/28 ,  A61B17/3211 ,  A61B2090/0814 ,  A61F2/30767 ,  A61F2/4455 ,  A61F2002/30716 ,  A61F2250/0097 ,  A61F2310/00401 ,  A61F2310/00407 ,  A61F2310/00425 ,  A61F2310/00431 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61L2/07 ,  A61L27/30 ,  A61L27/306 ,  A61L31/082 ,  A61L31/088 ,  A61L2202/21 ,  A61L2202/24 ,  A61L2420/02 ,  A61L2420/04 ,  A61L2420/08

摘要： A surface coating for a medical instrument includes an interference filter having at least one dielectric layer and at least one metallic layer arranged one above another. At least one of the at least one metallic layer and the at least one dielectric layer is adapted to be structurally altered by action of a corrosive environment on the surface coating such that the surface coating is convertible from a first state to a second state. In the first state, the surface coating has a first spectral reflectivity. In the second state, the surface coating has a second spectral reflectivity that is different from the first spectral reflectivity.

公开(公告)号：US20130304226A1

公开(公告)日：2013-11-14

申请号：US13770640

申请日：2013-02-19

申请人： ASCENSION ORTHOPEDICS, INC.

发明人： Joseph P. Ritz ,  Clive Scott

IPC分类号： A61L27/08

CPC分类号： A61L27/08 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/4003 ,  A61F2/4241 ,  A61F2002/30163 ,  A61F2002/30299 ,  A61F2002/30769 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2002/4007 ,  A61F2002/4248 ,  A61F2002/4251 ,  A61F2230/0028 ,  A61F2230/0093 ,  A61F2310/00173 ,  A61F2310/00407 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61F2310/00574 ,  A61L27/303 ,  A61L27/306 ,  A61L2430/02

摘要： Methods for forming bone implants for the repair of the ends of bones at orthopedic joints, which implants have a Young's modulus close to that of human cortical bone. Substrates of dense isotropic graphite are coated overall with hard, microporous, isotropic pyrocarbon of specific character such that it can be polished to serve as an articular surface and can also securely receive an anchoring first metal layer through PVD. The first layer has a character such that, by thermal spraying a second biocompatible metal layer thereupon, fusion occurs and thereby anchors an outermost layer that is formed with a network of randomly interconnected pores and a surface character of peaks and valleys designed to promote enhanced appositional growth of cortical bone at the interface therewith.

摘要翻译： 用于形成用于修复矫形关节骨头端部的骨植入物的方法，所述植入物的杨氏模量接近人皮层骨的杨氏模量。 致密各向同性石墨的基体整体涂覆有特定特性的硬质，微孔，各向同性的热解碳，使得其可以被抛光以用作关节表面，并且还可以通过PVD可靠地接收固定的第一金属层。 第一层具有这样的特征，使得通过热喷涂第二生物相容性金属层，发生融合，从而锚定形成有随机互连孔的网络的最外层和设计用于促进增强的附着的峰和谷的表面特征 皮质骨与其界面的生长。

公开(公告)号：US20010036530A1

公开(公告)日：2001-11-01

申请号：US09818054

申请日：2001-03-26

申请人： KYOCERA CORPORATION

发明人： Iwao Noda ,  Junji Ikeda ,  Takefumi Nakanishi ,  Hiroyuki Kitano ,  Shingo Masuda

IPC分类号： A61F002/28 ,  A61F002/02

CPC分类号： C04B41/90 ,  A61C13/0003 ,  A61C13/0006 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2002/30981 ,  A61F2310/00203 ,  A61F2310/00227 ,  A61F2310/00239 ,  A61F2310/00281 ,  A61F2310/00311 ,  A61F2310/00317 ,  A61F2310/00323 ,  A61F2310/00401 ,  A61F2310/00407 ,  A61F2310/00413 ,  A61F2310/00431 ,  A61F2310/00437 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00514 ,  A61F2310/0052 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61F2310/00568 ,  A61F2310/00604 ,  A61F2310/0061 ,  A61F2310/00616 ,  A61F2310/00634 ,  A61F2310/00742 ,  A61F2310/00796 ,  A61F2310/00868 ,  A61F2310/00874 ,  A61F2310/0088 ,  A61F2310/00928 ,  A61L27/04 ,  A61L27/10 ,  A61L27/105 ,  A61L27/306 ,  A61L27/42 ,  A61L2420/08 ,  C04B41/009 ,  C04B41/52 ,  C04B2111/00405 ,  C04B2111/00836 ,  Y10T428/2405 ,  C04B41/4529 ,  C04B41/5133 ,  C04B41/5068 ,  C04B41/522 ,  C04B41/4527 ,  C04B41/5048 ,  C04B35/10 ,  C04B35/00 ,  C04B35/48

摘要： The present invention provides a biomedical implant material comprising a substrate for biomedical implant made of a ceramic material, a first coating layer formed on the surface of said substrate by low-thermal impact coating process, and a second coating layer formed on said first coating layer via a metallic layer formed by thermal spraying process, and a method of producing the same. According to the biomedical implant material, it is made possible to prevent cracks from occurring in the ceramic substrate, and to secure sufficient bonding strength between the thermal-sprayed layer of titanium or the like onto the ceramic substrate.

摘要翻译： 本发明提供了一种生物医学植入材料，其包括由陶瓷材料制成的用于生物医学植入物的基底，通过低热冲击涂覆法形成在所述基底的表面上的第一涂层，以及形成在所述第一涂层上的第二涂层 通过热喷涂法形成的金属层及其制造方法。 根据生物医学植入材料，可以防止在陶瓷基板中发生裂纹，并且确保钛等的热喷涂层在陶瓷基板上的充分的接合强度。

公开(公告)号：US09901456B2

公开(公告)日：2018-02-27

申请号：US13884439

申请日：2011-11-09

申请人： Toshio Matsumoto ,  Yuzo Daigo ,  Shinichi Ohmori ,  Komei Kato

发明人： Toshio Matsumoto ,  Yuzo Daigo ,  Shinichi Ohmori ,  Komei Kato

IPC分类号： A61F2/44 ,  A61F2/30

CPC分类号： A61F2/442 ,  A61F2/4465 ,  A61F2002/30011 ,  A61F2002/30013 ,  A61F2002/30471 ,  A61F2002/30472 ,  A61F2002/30492 ,  A61F2002/30616 ,  A61F2002/30841 ,  A61F2002/30892 ,  A61F2002/30967 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/448 ,  A61F2310/00023 ,  A61F2310/00431 ,  A61F2310/00443 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00514 ,  A61F2310/00532 ,  A61F2310/00544 ,  A61F2310/00562 ,  A61F2310/00976

摘要： A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes dense sheets having a dense part on at least a surface thereof and porous sheets having a porous part on at least a surface thereof. The porous part has a larger porosity than a porosity of the dense part. Each of the porous sheets is sandwiched between the pair of dense sheets. According to the present invention, it is possible to maintain an appropriate size between the vertebral bodies (intervertebral space).

公开(公告)号：US08932663B2

公开(公告)日：2015-01-13

申请号：US13770640

申请日：2013-02-19

申请人： Ascension Orthopedics, Inc.

发明人： Joseph P. Ritz ,  Clive Scott

IPC分类号： A61F2/28 ,  B05D3/10 ,  C23C16/00 ,  A61L27/08 ,  A61L27/30 ,  A61F2/40 ,  A61F2/30 ,  A61F2/42

CPC分类号： A61L27/08 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/4003 ,  A61F2/4241 ,  A61F2002/30163 ,  A61F2002/30299 ,  A61F2002/30769 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2002/4007 ,  A61F2002/4248 ,  A61F2002/4251 ,  A61F2230/0028 ,  A61F2230/0093 ,  A61F2310/00173 ,  A61F2310/00407 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0055 ,  A61F2310/00574 ,  A61L27/303 ,  A61L27/306 ,  A61L2430/02

摘要： Methods for forming bone implants for the repair of the ends of bones at orthopedic joints, which implants have a Young's modulus close to that of human cortical bone. Substrates of dense isotropic graphite are coated overall with hard, microporous, isotropic pyrocarbon of specific character such that it can be polished to serve as an articular surface and can also securely receive an anchoring first metal layer through PVD. The first layer has a character such that, by thermal spraying a second biocompatible metal layer thereupon, fusion occurs and thereby anchors an outermost layer that is formed with a network of randomly interconnected pores and a surface character of peaks and valleys designed to promote enhanced appositional growth of cortical bone at the interface therewith.

摘要翻译： 用于形成用于修复矫形关节骨头端部的骨植入物的方法，所述植入物的杨氏模量接近人皮层骨的杨氏模量。 致密各向同性石墨的基体整体涂覆有特定特性的硬质，微孔，各向同性的热解碳，使得其可以被抛光以用作关节表面，并且还可以通过PVD可靠地接收固定的第一金属层。 第一层具有这样的特征，使得通过热喷涂第二生物相容性金属层，发生融合，从而锚定形成有随机互连孔的网络的最外层和设计用于促进增强的附着的峰和谷的表面特征 皮质骨与其界面的生长。

公开(公告)号：US5723011A

公开(公告)日：1998-03-03

申请号：US219247

申请日：1994-03-28

申请人： Thirumalai Devanathan ,  Steve T. Lin

发明人： Thirumalai Devanathan ,  Steve T. Lin

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61F2/36 ,  B22F7/00 ,  A61F2/28

CPC分类号： A61F2/30907 ,  B22F7/004 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/367 ,  A61F2002/30044 ,  A61F2002/30112 ,  A61F2002/30153 ,  A61F2002/30158 ,  A61F2002/30322 ,  A61F2002/30929 ,  A61F2002/30967 ,  A61F2002/30968 ,  A61F2002/3631 ,  A61F2230/0004 ,  A61F2230/0019 ,  A61F2230/0026 ,  A61F2250/0026 ,  A61F2250/0046 ,  A61F2310/00011 ,  A61F2310/00395 ,  A61F2310/00497

摘要： This invention solves the above identified limitation by providing a prosthetic implant having a porous surface layer metallurgically bonded to the implant body, wherein a barrier film of metal is positioned between a portion of the porous surface layer and the implant body at areas of stress. By preventing bonding and thereby the formation of notches at strategic locations about the implant, the overall fatigue strength of the implant may be increased. In the preferred embodiment, the film of metal is formed from molybdenum which has a higher melting temperature than titanium which is commonly used for porous layers and the implant body. By preventing notches at strategically significant areas about the implant, designers of prosthetic implants are less limited in the amount or location of the porous surface layer to be metallurgically bonded to the implant.

摘要翻译： 本发明通过提供具有冶金结合到植入体的多孔表面层的假体植入物来解决上述确定的限制，其中金属的阻挡膜位于多孔表面层的一部分和应力区域的植入物本体之间。 通过防止接合，从而在围绕植入物的关键位置形成凹口，可以增加植入物的整体疲劳强度。 在优选的实施方案中，金属膜由具有比通常用于多孔层和植入物体的钛的熔融温度更高的钼形成。 通过防止关于植入物的战略重要区域的缺口，假体植入物的设计者在冶金结合到植入物的多孔表面层的量或位置上的限制较少。

公开(公告)号：US08894824B2

公开(公告)日：2014-11-25

申请号：US11168050

申请日：2005-06-28

申请人： David A. Glocker ,  Mark M. Romach

发明人： David A. Glocker ,  Mark M. Romach

IPC分类号： C23C14/00 ,  C23C14/32 ,  C23C14/22 ,  A61L27/30 ,  A61F2/30

CPC分类号： C23C14/225 ,  A61F2/30767 ,  A61F2002/30929 ,  A61F2002/3098 ,  A61F2310/00407 ,  A61F2310/00449 ,  A61F2310/00485 ,  A61F2310/00497 ,  A61F2310/00544 ,  A61F2310/0088 ,  A61F2310/0097 ,  A61L27/306

摘要： A medical implant has a microscopically rough outer coating that serves to bond the implant to animal tissue. The coating is applied to the implant by physical vapor deposition. The coating preferable is applied via a generally oblique coating flux or a low energy coating flux. In some embodiments, the coating has pores. The pores can contain a drug, which can diffuse over a period of time. The coating may be partially nonporous to protect the implant from corrosion. The coating can have an outer porous layer that can bond with animal tissue easily.

摘要翻译： 医疗植入物具有显微粗糙的外涂层，其用于将植入物结合到动物组织。 通过物理气相沉积将涂层施加到植入物上。 优选的涂层通过大体上倾斜的涂层焊剂或低能量涂层焊剂施加。 在一些实施方案中，涂层具有孔。 毛孔可以含有药物，其可以在一段时间内扩散。 涂层可能是部分无孔的，以保护植入物免受腐蚀。 涂层可以具有能够容易地与动物组织结合的外部多孔层。

公开(公告)号：US20130274884A1

公开(公告)日：2013-10-17

申请号：US13884357

申请日：2011-11-09

申请人： Toshio Matsumoto ,  Yuzo Daigo ,  Shinichi Ohmori ,  Komei Kato

发明人： Toshio Matsumoto ,  Yuzo Daigo ,  Shinichi Ohmori ,  Komei Kato

IPC分类号： A61F2/44

CPC分类号： A61F2/4455 ,  A61F2/30771 ,  A61F2/44 ,  A61F2/442 ,  A61F2/4465 ,  A61F2002/30011 ,  A61F2002/30224 ,  A61F2002/30454 ,  A61F2002/30471 ,  A61F2002/30472 ,  A61F2002/30492 ,  A61F2002/30616 ,  A61F2002/30841 ,  A61F2002/30892 ,  A61F2002/3092 ,  A61F2002/30967 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2310/00023 ,  A61F2310/00431 ,  A61F2310/00443 ,  A61F2310/00485 ,  A61F2310/00491 ,  A61F2310/00497 ,  A61F2310/00514 ,  A61F2310/00532 ,  A61F2310/00544 ,  A61F2310/00562 ,  A61F2310/00976

摘要： A vertebral body spacer of the present invention is used by being inserted between a vertebral body and a vertebral body (intervertebral space). The vertebral body spacer has a block body constituted of titanium or a titanium alloy as a main component thereof, and provided with a pair of contact surfaces to be made contact with the vertebral body and the vertebral body. The block body includes needle parts formed into a needle shape having both end portions and a porous part having through holes passing through the porous part in a thickness direction thereof, and a porosity of at least a surface of the porous part is larger than a porosity of each of the needle parts. The needle parts are inserted into the through holes so that the both end portions are projected from the contact surfaces.

摘要翻译： 通过插入椎体和椎体（椎间空间）来使用本发明的椎体间隔件。 椎体间隔物具有由钛或钛合金作为其主要成分构成的块体，并且具有与椎体和椎体接触的一对接触面。 块体包括形成为具有两端部的针状的针部和具有贯穿多孔部的厚度方向的贯通孔的多孔部，多孔部的至少表面的孔隙率大于孔隙率 的每个针部分。 针部分插入到通孔中，使得两个端部从接触表面突出。