公开(公告)号：US08889652B2

公开(公告)日：2014-11-18

申请号：US12448064

申请日：2007-12-06

申请人： Kenji Miyamoto ,  Keiji Yoshioka ,  Katsuya Takahashi

发明人： Kenji Miyamoto ,  Keiji Yoshioka ,  Katsuya Takahashi

IPC分类号： A61K31/728 ,  A61K31/738 ,  A61P19/02

CPC分类号： A61K31/728 ,  A61K9/0019 ,  A61K9/06 ,  A61K31/738 ,  A61K47/02 ,  C08B37/0072

摘要： The present invention relates to an injection solution for intra-articular administration for treating arthritic disorders comprising a cross-linked hyaluronic acid derivative wherein part of functional groups of a hyaluronic acid are cross-linked with a cross-linking group to the extent of 0.6 to 15% of cross-linking extent as an active ingredient in an amount having a long-lasting analgesic effect and a pharmaceutically acceptable carrier, and an analgesic composition for suppressing a cartilage degeneration caused by arthritic disorders or a composition for suppressing a cartilage degeneration or an inflammation of synovium caused by arthritic disorders each comprising the cross-linked hyaluronic acid derivative and a pharmaceutically acceptable carrier.

摘要翻译： 本发明涉及用于治疗关节炎疾病的关节内给药的注射液，其包含交联的透明质酸衍生物，其中透明质酸的官能团的一部分与交联基团交联至0.6〜 具有持久镇痛效果的量的作为活性成分的交联程度的15％和药学上可接受的载体，以及用于抑制由关节炎病症引起的软骨退化的镇痛组合物或用于抑制软骨退化的组合物或 由关节炎病症引起的滑膜的炎症各自包含交联的透明质酸衍生物和药学上可接受的载体。

公开(公告)号：US20080249062A1

公开(公告)日：2008-10-09

申请号：US11579673

申请日：2005-04-28

申请人： Katsuya Takahashi ,  Tomoya Sato ,  Yukihiro Matsuyama

发明人： Katsuya Takahashi ,  Tomoya Sato ,  Yukihiro Matsuyama

IPC分类号： A61K31/737

CPC分类号： A61L27/20 ,  A61L2430/38 ,  C08L5/08

摘要： The present invention provides a nucleus pulposus filler or the like which is to be packed into an area in deformed intervertebral disc wherein normal nucleus should be located and can be stabley maintained for a long time. More preferably, the present invention provides a nucleus pulposus filler comprising a crosslinked chondroitin sulfate as an active ingredient. The photocrosslinked chondroitin sulfate is preferably the following one: a photocrosslinked chondroitin sulfate obtainable by freezing a photoreactive chondroitin sulfate-containing solution comprising: a photoreactive chondroitin sulfate to which a photoreactive group is bound; an aqueous solvent capable of dissolving the photoreactive chondroitin sulfate; and any one substance selected from the group consisting of an alcohol having aqueous solvent miscibility, a surfactant, and a cheleting agent; irradiating the resulting frozen product with light; and then melting the frozen product. The filler can be provided as a kit by packing it into a container from which the filler can be pushed out.

摘要翻译： 本发明提供一种髓核填充物等，其将被包装在变形椎间盘的区域中，其中应当定位正常的核并且可以长期稳定地保持。 更优选地，本发明提供了包含交联的硫酸软骨素作为活性成分的髓核填充物。 光交联的硫酸软骨素优选如下：通过冷冻含有光反应性硫酸软骨素溶液的光交联的软骨素硫酸盐，其包含：光反应性硫酸软骨素结合的光反应性硫酸软骨素; 能够溶解光反应性硫酸软骨素的水性溶剂; 和选自具有水溶剂混溶性的醇，表面活性剂和螯合剂的任何一种物质; 用光照射所得冷冻产品; 然后熔化冷冻产品。 填料可以通过将其包装到容器中作为试剂盒提供，填料可从该容器中推出。

公开(公告)号：US06232301B1

公开(公告)日：2001-05-15

申请号：US09142032

申请日：1998-08-27

申请人： Katsuya Takahashi ,  Satoshi Miyauchi

发明人： Katsuya Takahashi ,  Satoshi Miyauchi

IPC分类号： A61K3170

CPC分类号： A61K31/715 ,  A61K9/0034

摘要： In order to provide an agent for treatment of bladder troubles that has vesical mucosa epithelium dilatation promoting action and/or vesical mucosa healing action, and exhibits excellent curative effect for bladder troubles, in particular, non-bacterial intractable bladder troubles, the agent for treatment of bladder troubles is formulated with hyaluronic acid and/or a pharmaceutically acceptable salt thereof, preferably hyaluronic acid and/or a pharmaceutically acceptable salt thereof having the following physicochemical properties: (A) endotoxin content; 0.03 EU (endotoxin unit)/10 mg or less, (B) sulfur content; 0.01% or less as determined by coulometric titration, (C) iron content; 20 ppm or less, (D) protein content; 0.1% or less, and (E) weight average molecular weight; 500,000 or more, in an amount effective for promoting vesical mucosa epithelium dilatation and/or healing vesical mucosa, preferably in an amount of 0.2-0.6% by weight based on total amount of the agent.

摘要翻译： 为了提供具有膀胱粘膜上皮扩张促进作用和/或膀胱粘膜愈合作用的膀胱麻烦的治疗剂，对膀胱麻烦，特别是非细菌难治性膀胱麻烦，治疗剂 膀胱麻烦的透明质酸和/或其药学上可接受的盐，优选透明质酸和/或其药学上可接受的盐，具有以下物理化学性质：（A）内毒素含量; 0.03欧盟（内毒素单位）/ 10毫克或更少，（B）硫含量; 0.01％以下，通过库仑滴定测定，（C）铁含量; 20ppm以下，（D）蛋白质含量; 0.1％以下，（E）重均分子量; 500,000或更多，其量有效促进膀胱粘膜上皮扩张和/或愈合膀胱粘膜，优选为基于试剂总量的0.2-0.6重量％。

公开(公告)号：US5112385A

公开(公告)日：1992-05-12

申请号：US545837

申请日：1990-06-29

申请人： Isao Hashimoto ,  Tatsuyodihi Ishida ,  Kazutaka Tsuru ,  Yuji Yamada ,  Takeshige Miyazawa ,  Yasuo Nakamura ,  Susumu Katou ,  Katsuya Takahashi

发明人： Isao Hashimoto ,  Tatsuyodihi Ishida ,  Kazutaka Tsuru ,  Yuji Yamada ,  Takeshige Miyazawa ,  Yasuo Nakamura ,  Susumu Katou ,  Katsuya Takahashi

IPC分类号： A01N43/28 ,  A01N43/32 ,  A01N43/38 ,  A01N47/28 ,  A01N47/32 ,  A01N47/34 ,  A01N47/38 ,  C07C275/64 ,  C07D209/02 ,  C07D209/44 ,  C07D213/64 ,  C07D213/68 ,  C07D213/79 ,  C07D213/80 ,  C07D213/84 ,  C07D217/06 ,  C07D221/22 ,  C07D237/14 ,  C07D239/34 ,  C07D239/56 ,  C07D241/18 ,  C07D251/26 ,  C07D251/30 ,  C07D251/38 ,  C07D263/06 ,  C07D265/02 ,  C07D265/06 ,  C07D295/215 ,  C07D453/06 ,  C07D487/08 ,  C07D498/08

CPC分类号： C07D213/64 ,  A01N43/28 ,  A01N43/32 ,  A01N43/38 ,  A01N47/28 ,  A01N47/32 ,  A01N47/34 ,  A01N47/38 ,  C07C275/64 ,  C07D209/02 ,  C07D209/44 ,  C07D213/68 ,  C07D213/79 ,  C07D213/80 ,  C07D213/84 ,  C07D217/06 ,  C07D221/22 ,  C07D237/14 ,  C07D239/34 ,  C07D239/56 ,  C07D241/18 ,  C07D251/26 ,  C07D251/30 ,  C07D251/38 ,  C07D263/06 ,  C07D265/02 ,  C07D265/06 ,  C07D295/215 ,  C07D453/06 ,  C07D487/08

摘要： A substituted aryloxyurea of the formula: ##STR1## wherein Ar represents ##STR2## in which X.sup.7 represents a hydrogen atom, a halogen atom, a cyano group, a lower alkoxy group or a trifluoromethyl group, andR.sup.1 and R.sup.2 together form together with carbon and the nitrogen atom to which they are bonded a 4-8 membered heterocyclic ring.The substituted aryloxyureas exhibit an excellent herbicidal efficacy against weeds when applied, for example, to the weeds in a wide range of period from a preemergence stage to a growth stage.The substituted aryloxyureas of the invention have the excellent advantage of maintaining high safety on crops or crop plants in spite of their herbicidal efficacy.

公开(公告)号：US4838924A

公开(公告)日：1989-06-13

申请号：US39457

申请日：1987-04-01

申请人： Tetsuo Takematsu ,  Daisuke Fukuoka ,  Katsuya Takahashi ,  Isao Hashimoto

发明人： Tetsuo Takematsu ,  Daisuke Fukuoka ,  Katsuya Takahashi ,  Isao Hashimoto

IPC分类号： A01N47/30 ,  A01N47/36 ,  C07D307/77 ,  C07D307/79 ,  C07D307/83 ,  C07D307/86 ,  C07D307/91 ,  C07D307/94 ,  C07D311/04 ,  C07D311/20 ,  C07D311/22 ,  C07D311/58 ,  C07D311/64 ,  C07D311/72 ,  C07D311/78 ,  C07D311/94 ,  C07D317/46 ,  C07D317/64 ,  C07D405/12 ,  C07D493/10

CPC分类号： C07D307/79 ,  A01N47/30 ,  A01N47/36 ,  C07D307/83 ,  C07D307/86 ,  C07D307/91 ,  C07D307/94 ,  C07D311/04 ,  C07D311/20 ,  C07D311/22 ,  C07D311/58 ,  C07D311/64 ,  C07D311/72 ,  C07D311/78 ,  C07D311/94 ,  C07D317/46 ,  C07D317/64 ,  C07D405/12 ,  C07D493/10

摘要： This invention relates to novel compounds of formula [I], a process for their production, and their use as a herbicide. ##STR1## wherein A represents the bond ##STR2## in which X is a hydrogen atom, a chlorine atom, a nitro group or a trifluoromethyl group;B represents a hydrogen atom, a methyl group or a methoxy group; andAr represents one member selected from the group consisting of ##STR3## in which R.sup.1 to R.sup.38, are as defined hereinafter.

摘要翻译： PCT No.PCT / JP86 / 00398 Sec。 371日期1987年4月1日 102（e）日期1987年4月1日PCT提交1986年8月4日PCT公布。 第WO87 / 00840号公报 日本公开1987年2月12日。本发明涉及式[I]的新化合物，其生产方法及其作为除草剂的用途。 其中A表示其中X为氢原子，氯原子，硝基或三氟甲基的键。 B表示氢原子，甲基或甲氧基; 并且Ar表示从下列定义的从 + TR 中选择的一个成员。

公开(公告)号：US11066269B2

公开(公告)日：2021-07-20

申请号：US16843227

申请日：2020-04-08

申请人： Katsuya Takahashi

发明人： Katsuya Takahashi

IPC分类号： B65H45/20 ,  B65H45/14 ,  B65H45/04

摘要： A sheet folding processing apparatus suppresses an increase in size and cost of the apparatus and performs folding processing on continuously conveyed sheets. In the sheet folding processing apparatus, a sheet conveyed by a feeding roller pair and hang in a loop shape in a loop forming space is pushed into a nipping portion of a folding roller pair by a pushing plate, so that the sheet is folded in a Z-shape to form a plurality of fold lines. The sheet is conveyed in the conveyance direction until the sheet rear end passes through the feeding roller pair, and after the sheet rear end is stored in a loop forming space by moving the pushing plate from a position for pushing the sheet into a nipping portion to a retracting position, the reinforcing processing of the fold line of the sheet is performed by an additional folding unit.

公开(公告)号：US20060245428A1

公开(公告)日：2006-11-02

申请号：US10547212

申请日：2004-02-19

申请人： Kaoru Yanamoto ,  Tsuyoshi Masato ,  Masaru Ogihara ,  Katsuya Takahashi

发明人： Kaoru Yanamoto ,  Tsuyoshi Masato ,  Masaru Ogihara ,  Katsuya Takahashi

IPC分类号： H04L12/56

CPC分类号： H04L65/608 ,  H04L1/1835 ,  H04L1/1848 ,  H04L1/1874 ,  H04L29/06 ,  H04L65/80 ,  H04L69/16 ,  H04L69/164 ,  H04L69/22 ,  H04L69/40

摘要： The present invention relates to a transmitter and a receiver designed to improve the reliability of communications therebetween. During communication processes under UDP adopted as the transport layer, data having RTP headers is transmitted and received between the transmitter and the receiver. The receiver references the sequence numbers in the received RTP headers to verify the continuity of the numbers. If any data with a serially continuous sequence number is not received, the receiver finds that data to be missing and requests the transmitter to retransmit the data associated with the missing sequence number. The receiver then acquires the missing data that has been retransmitted. This invention applies to transmitters that transmit data and to receivers that receive the transmitted data.

摘要翻译： 本发明涉及一种设计用于提高其间通信的可靠性的发射机和接收机。 在采用UDP作为传输层的通信过程中，在发射机和接收机之间发送和接收具有RTP头的数据。 接收机引用接收的RTP报头中的序列号来验证数字的连续性。 如果没有接收到具有连续序列号的任何数据，则接收机发现数据丢失，并请求发送器重传与丢失序列号相关联的数据。 然后，接收器获取已重传的丢失数据。 本发明适用于发送数据的发送机和接收发送数据的接收机。

公开(公告)号：US5837791A

公开(公告)日：1998-11-17

申请号：US915914

申请日：1997-08-21

申请人： Toshihiro Sagane ,  Masaaki Kawasaki ,  Hidenari Nakahama ,  Tatsuyoshi Ishida ,  Katsuya Takahashi ,  Toshiyuki Tsutsui ,  Hitoshi Onishi ,  Masaaki Yasuda ,  Noriaki Kihara

发明人： Toshihiro Sagane ,  Masaaki Kawasaki ,  Hidenari Nakahama ,  Tatsuyoshi Ishida ,  Katsuya Takahashi ,  Toshiyuki Tsutsui ,  Hitoshi Onishi ,  Masaaki Yasuda ,  Noriaki Kihara

IPC分类号： C07C2/04 ,  C07C11/21 ,  C08F4/659 ,  C08F4/6592 ,  C08F210/18 ,  C08F236/20 ,  C08F255/02

CPC分类号： C08F255/02 ,  C07C11/21 ,  C07C2/04 ,  C08F210/18 ,  C07C2531/14 ,  C07C2531/24 ,  C08F4/65908 ,  C08F4/6592 ,  C08F4/65922

摘要： A novel unsaturated copolymer of ethylene comprises a random copolymer of (i) ethylene, (ii) an .alpha.-olefin of 3 to 20 carbon atoms and (iii) at least one straight chain or branched chain nonconjugated triene or tetraene having one vinyl group in the molecule, which contains 30-92% by mol of ethylene units (i), 6-70% by mol of .alpha.-olefin units (ii) and 0.1-30% by mol of triene or tetraene units (iii), and which has a molar ratio of ethylene units (i) to .alpha.-olefin units (ii) of 40/60 to 92/8 (ethylene units (i)/.alpha.-olefin units (ii)) and an intrinsic viscosity (.eta.), measured in Decalin at 135.degree. C., of 0.05 to 10 dl/g. This novel unsaturated copolymer of ethylene is excellent in weathering resistance, heat resistance and ozone resistance and has a high vulcanizing rate.

摘要翻译： 一种新型的乙烯不饱和共聚物包括（i）乙烯，（ii）3-20个碳原子的α-烯烃和（iii）至少一个具有一个乙烯基的直链或支链非共轭三烯或四烯的无规共聚物 该分子含有30-92摩尔％的乙烯单元（i），6-70摩尔％的α-烯烃单元（ii）和0.1-30摩尔％的三烯或四烯单元（iii），其中 具有40/60至92/8（乙烯单元（i）/α-烯烃单元（ii））的乙烯单元（i）与α-烯烃单元（ii）的摩尔比和特性粘度（η），测量 在135℃的十氢化萘中为0.05〜10dl / g。 该新颖的乙烯不饱和共聚物耐候性，耐热性和耐臭氧性优异，硫化速度高。

公开(公告)号：US5011950A

公开(公告)日：1991-04-30

申请号：US151594

申请日：1988-02-02

申请人： Daisuke Fukuoka ,  Katsuya Takahashi ,  Isao Hashimoto

发明人： Daisuke Fukuoka ,  Katsuya Takahashi ,  Isao Hashimoto

IPC分类号： C07D213/73 ,  C07D307/79 ,  C07D307/80 ,  C07D307/83 ,  C07D307/86 ,  C07D307/91 ,  C07D311/04 ,  C07D311/20 ,  C07D311/22 ,  C07D311/58 ,  C07D311/64 ,  C07D311/78 ,  C07D311/94 ,  C07D311/96 ,  C07D317/46 ,  C07D317/54 ,  C07D317/64 ,  C07D317/72 ,  C07D405/12 ,  C07D493/08 ,  C07D493/10

CPC分类号： C07D307/79 ,  C07D307/83 ,  C07D307/86 ,  C07D307/91 ,  C07D311/20 ,  C07D311/22 ,  C07D311/58 ,  C07D311/64 ,  C07D311/78 ,  C07D311/96 ,  C07D317/46 ,  C07D317/64 ,  C07D317/72 ,  C07D405/12 ,  C07D493/10

摘要： Novel aromatic amine derivatives of specific structure are useful intermediates for herbicides. The aromatic amine compounds have the structure shown by formula [I]: ##STR1## wherein Ar and A are as defined herein.

公开(公告)号：US08416524B2

公开(公告)日：2013-04-09

申请号：US13029143

申请日：2011-02-17

申请人： Masayoshi Saichi ,  Kazuhiko Fukushima ,  Hironori Ando ,  Kazushi Miura ,  Katsuya Takahashi ,  Takehito Tamaoka ,  Jonathan M. Garbarino ,  Robert N. Lion

发明人： Masayoshi Saichi ,  Kazuhiko Fukushima ,  Hironori Ando ,  Kazushi Miura ,  Katsuya Takahashi ,  Takehito Tamaoka ,  Jonathan M. Garbarino ,  Robert N. Lion

IPC分类号： G11B19/20

CPC分类号： G11B19/2009 ,  H02K3/521 ,  H02K5/225 ,  H02K2203/03

摘要： A spindle motor includes a base portion, a rotor hub, a stator, and a circuit board. The base portion preferably includes a through hole and is arranged to spread out radially around a central axis. The rotor hub is arranged above the base portion to rotate about the central axis. The stator is arranged above the base portion, and includes coils each including at least one lead wire. The circuit board is arranged radially outward of the through hole, and arranged on a lower surface of the base portion. The base portion includes a communicating groove arranged to join the through hole and the circuit board to each other. The at least one lead wire of the coils is arranged to pass inside the through hole and the communicating groove to be electrically connected to the circuit board. The through hole is sealed with a sealant.

摘要翻译： 主轴电动机包括基部，转子毂，定子和电路板。 基部优选地包括通孔并布置成围绕中心轴径向扩展。 转子毂布置在基部上方以围绕中心轴线旋转。 定子布置在基部的上方，并且包括各自包括至少一根引线的线圈。 电路板布置在通孔的径向外侧，并且布置在基部的下表面上。 基部包括连通槽，该连通槽将通孔和电路板彼此连接。 线圈的至少一根引线布置成通过通孔和连通槽内的电连接到电路板。 通孔用密封剂密封。