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    Polymer blends for use in making medical devices including catheters and balloons for dilatation catheters
    6.
    发明授权
    Polymer blends for use in making medical devices including catheters and balloons for dilatation catheters 失效

    公开(公告)号：US5554120A

    公开(公告)日：1996-09-10

    申请号：US280764

    申请日：1994-07-25

    申请人： Ziyun Chen ,  Tai Cheng ,  Ketan Muni ,  Udayan Patel ,  Robert Saltman

    发明人： Ziyun Chen ,  Tai Cheng ,  Ketan Muni ,  Udayan Patel ,  Robert Saltman

    IPC分类号： A61L29/00 ,  A61F2/958 ,  A61L29/04 ,  A61M25/00 ,  A61M25/16 ,  C08L23/02 ,  C08L67/00 ,  C08L67/02 ,  C08L77/00 ,  A61M25/10 ,  A61M29/02

    CPC分类号： A61M25/1029 ,  A61L29/049 ,  C08L67/02 ,  A61M2025/1031 ,  A61M25/0009

    摘要： A combination of polymeric components provides desired characteristics in forming medical instruments such as catheters and balloons for dilatation catheters. For example, a balloon material is formed from a blend of polymeric components, including a first crystalline polymeric component and a second softening polymeric component. Where the first two components are generally incompatible, the balloon material can also include a third compatibilizing agent to facilitate blending the first two polymeric components together. The first polymeric component can be a branched or straight chain polyamide having a molecular weight of at least about 5000, or a polyester prepared from aromatic dicarboxylic acids having 8 to 14 carbon atoms or aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and at least one glycol having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol. The second polymeric component can be a polyolefin, an ethylene copolymer, a polyester block copolymer, or a polyamide block copolymer. The third polymeric component is preferably an ethylene copolymer having the formula E/X/Y where E is ethylene; X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1-12 carbon atoms; and Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with the first polymeric component. The polymeric blend can be irradiated to enhance the properties of the balloon material, including significantly increasing burst pressures.

    COREWIRE DESIGN AND CONSTRUCTION FOR MEDICAL DEVICES
    7.
    发明申请
    COREWIRE DESIGN AND CONSTRUCTION FOR MEDICAL DEVICES 有权
    医疗设备的COREWIRE设计和构造

    公开(公告)号：US20090227900A1

    公开(公告)日：2009-09-10

    申请号：US12045308

    申请日：2008-03-10

    申请人： Isaac Kim ,  Ketan Muni

    发明人： Isaac Kim ,  Ketan Muni

    IPC分类号： A61M25/01 ,  B23P11/00

    CPC分类号： A61M25/09 ,  A61B17/24 ,  A61M29/02 ,  A61M2025/09083 ,  A61M2029/025 ,  Y10T29/49908

    摘要： A guidewire for use in ear, nose and throat procedures may include an elongate core wire having a proximal region and a distal region. The distal region of the core wire may include a flattened portion adapted to provide preferential flexure along at least one axis of the wire. The distal region of the core wire may include a tip portion distal of the flattened portion, where at least one cross-sectional dimension of the tip portion is greater than at least one cross-sectional dimension of the flattened portion. The guidewire may include an outer coil disposed around at least a portion of the elongate core wire. The guidewire may also include an atraumatic tip coupled to the core wire or the outer coil.

    摘要翻译： 用于耳，鼻和咽喉手术的导丝可以包括具有近端区域和远侧区域的细长芯线。 芯线的远侧区域可以包括适于沿着线的至少一个轴线提供优先挠曲的平坦部分。 芯线的远侧区域可以包括在平坦部分的远侧的尖端部分，其中尖端部分的至少一个横截面尺寸大于平坦部分的至少一个横截面尺寸。 导丝可以包括围绕细长芯线的至少一部分设置的外部线圈。 导丝还可以包括连接到芯线或外线圈的无创尖端。

    Catheters with non-removable guide members useable for treatment of sinusitis
    8.
    发明申请
    Catheters with non-removable guide members useable for treatment of sinusitis 有权
    导尿管与不可拆卸的导引器可用于治疗鼻窦炎

    公开(公告)号：US20070208301A1

    公开(公告)日：2007-09-06

    申请号：US11438090

    申请日：2006-05-18

    申请人： Philip Evard ,  Ketan Muni ,  John Morriss ,  John Chang

    发明人： Philip Evard ,  Ketan Muni ,  John Morriss ,  John Chang

    IPC分类号： A61M37/00

    CPC分类号： A61M29/02 ,  A61B17/24 ,  A61M25/10 ,  A61M2025/1075 ,  A61M2025/1079 ,  A61M2025/1093 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/0681

    摘要： Balloon catheter, guide catheter and method for dilating openings in paranasal sinuses. A non-removable guide member (e.g., guidewire) extends from the distal end of the balloon catheter. The non-removable guide member initially passes through the opening of the paranasal sinus and is followed by the catheter body on which the balloon is mounted. The balloon is then inflated causing dilation of the opening of the paranasal sinus. In some embodiments, the non-removable guide member may be shapeable so that the operator may place the non-removable guide member in a desired shape prior to insertion of the balloon catheter. In some embodiments, the length of the non-removable guide member may be adjustable such that the operator may adjust the length of the non-removable guide member prior to insertion of the balloon catheter.

    摘要翻译： 气囊导管，引导导管和扩大鼻旁窦口的方法。 不可移除的引导构件（例如，导丝）从气囊导管的远端延伸。 不可拆卸的引导构件最初穿过鼻旁窦的开口，并且其后是安装气囊的导管主体。 然后气球膨胀，导致鼻旁窦开口的扩张。 在一些实施例中，不可拆卸的引导构件可以是可成形的，使得操作者可以在插入球囊导管之前将不可拆卸的引导构件放置在期望的形状。 在一些实施例中，不可移除的引导构件的长度可以是可调节的，使得操作者可以在插入球囊导管之前调节不可移除的引导构件的长度。

    Corewire design and construction for medical devices
    10.
    发明授权
    Corewire design and construction for medical devices 有权
    Corewire医疗设备的设计和施工

    公开(公告)号：US08182432B2

    公开(公告)日：2012-05-22

    申请号：US12045308

    申请日：2008-03-10

    申请人： Isaac Kim ,  Ketan Muni

    发明人： Isaac Kim ,  Ketan Muni

    IPC分类号： A61M25/00

    CPC分类号： A61M25/09 ,  A61B17/24 ,  A61M29/02 ,  A61M2025/09083 ,  A61M2029/025 ,  Y10T29/49908

    摘要： A guidewire for use in ear, nose and throat procedures may include an elongate core wire having a proximal region and a distal region. The distal region of the core wire may include a flattened portion adapted to provide preferential flexure along at least one axis of the wire. The distal region of the core wire may include a tip portion distal of the flattened portion, where at least one cross-sectional dimension of the tip portion is greater than at least one cross-sectional dimension of the flattened portion. The guidewire may include an outer coil disposed around at least a portion of the elongate core wire. The guidewire may also include an atraumatic tip coupled to the core wire or the outer coil.

    摘要翻译： 用于耳，鼻和咽喉手术的导丝可以包括具有近端区域和远侧区域的细长芯线。 芯线的远侧区域可以包括适于沿着线的至少一个轴线提供优先挠曲的平坦部分。 芯线的远侧区域可以包括在平坦部分的远侧的尖端部分，其中尖端部分的至少一个横截面尺寸大于平坦部分的至少一个横截面尺寸。 导丝可以包括围绕细长芯线的至少一部分设置的外部线圈。 导丝还可以包括连接到芯线或外线圈的无创尖端。