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公开(公告)号:US20180202010A9
公开(公告)日:2018-07-19
申请号:US13468374
申请日:2012-05-10
IPC分类号: C12R1/01 , A23C9/123 , A61K35/745 , C12N1/20 , A23L33/135 , A23G9/36
CPC分类号: C12R1/01 , A23C9/1234 , A23G9/363 , A23L33/135 , A23V2002/00 , A23Y2300/55 , A61K35/745 , C12N1/20 , Y02A50/473 , A23V2200/3204 , A23V2200/324
摘要: Probiotic Bifidobacterium strain AH1714 is significantly immunomodulatory following oral consumption. The strain is useful as an immunomodulatory biotherapeutic agent.
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公开(公告)号:US09259019B2
公开(公告)日:2016-02-16
申请号:US13468512
申请日:2012-05-10
申请人: Liam O'Mahony , Barry Kiely
发明人: Liam O'Mahony , Barry Kiely
IPC分类号: C12N1/20 , A61P29/00 , A61P1/12 , A61P37/06 , A61P37/02 , A61K35/74 , A61P1/00 , A23K1/00 , A23L1/30 , C12R1/01 , A23K1/16 , A23K1/18
CPC分类号: A23K1/009 , A23K10/18 , A23K20/158 , A23K50/40 , A23L33/135 , A23Y2300/55 , A61K35/74 , C12R1/01
摘要: Bifidobacterium strain AH121A is significantly immunomodulatory following oral consumption. The strain is useful as an immunomodulatory biotherapeutic agent.
摘要翻译: 双歧杆菌菌株AH121A在口服消费后显着免疫调节。 该菌株可用作免疫调节生物治疗剂。
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公开(公告)号:US08357794B2
公开(公告)日:2013-01-22
申请号:US12451250
申请日:2008-05-02
申请人: Raymond Alan Grant , Liam O'Mahony , Barbara Sheil
发明人: Raymond Alan Grant , Liam O'Mahony , Barbara Sheil
IPC分类号: C08B37/00 , C07H5/04 , C07H5/06 , A01N43/04 , A61K31/715
CPC分类号: C07H5/06 , A23L33/135 , A61K31/715 , C08B37/006
摘要: An isolated polysaccharide has the structure [-β(1,3)-D-GalpNAc-β(1,4)-D-Glcp-]n The polysaccharide may be from a Bifidobacterium strain NCIMB41003. The polysaccharide exhibits immunomodulatory activity.
摘要翻译: 分离的多糖具有结构[ - &bgr;(1,3)-D-GalpNAc-&bgr;(1,4)-D-Glcp-] n多糖可以来自双歧杆菌菌株NCIMB41003。 多糖表现出免疫调节活性。
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公开(公告)号:US20130004540A1
公开(公告)日:2013-01-03
申请号:US13468512
申请日:2012-05-10
申请人: Liam O'mahony , Barry Kiely
发明人: Liam O'mahony , Barry Kiely
CPC分类号: A23K1/009 , A23K10/18 , A23K20/158 , A23K50/40 , A23L33/135 , A23Y2300/55 , A61K35/74 , C12R1/01
摘要: Bifidobacterium strain AH121A is significantly immunomodulatory following oral consumption. The strain is useful as an immunomodulatory biotherapeutic agent.
摘要翻译: 双歧杆菌菌株AH121A在口服消费后显着免疫调节。 该菌株可用作免疫调节生物治疗剂。
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公开(公告)号:US20110046084A1
公开(公告)日:2011-02-24
申请号:US12451250
申请日:2008-05-02
申请人: Raymond Alan Grant , Liam O'mahony , Barbara Sheil
发明人: Raymond Alan Grant , Liam O'mahony , Barbara Sheil
CPC分类号: C07H5/06 , A23L33/135 , A61K31/715 , C08B37/006
摘要: An isolated polysaccharide has the structure [-β(1,3)-D-GalpNAc-β(1,4)-D-Glcp-]n The polysaccharide may be from a Bifidobacterium strain NCIMB41003. The polysaccharide exhibits immunomodulatory activity.
摘要翻译: 分离的多糖具有结构[ - &bgr;(1,3)-D-GalpNAc-&bgr;(1,4)-D-Glcp-] n多糖可以来自双歧杆菌菌株NCIMB41003。 多糖表现出免疫调节活性。
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公开(公告)号:US07390519B2
公开(公告)日:2008-06-24
申请号:US11105590
申请日:2005-04-14
申请人: John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人: John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号: A61K35/747 , A23L33/135 , A23Y2220/79 , C12N1/20 , C12R1/225
摘要: A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
摘要翻译: A唾液乳杆菌菌株AH102,AH103,AH105,AH109或AH110或其突变体或变体可用于预防和/或治疗炎性活动,特别是不期望的胃肠炎症活动,例如炎性肠病或肠易激综合征。
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公开(公告)号:US20070141039A1
公开(公告)日:2007-06-21
申请号:US11478545
申请日:2006-06-29
CPC分类号: C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译: 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎性活动,特别是胃肠道炎症活动,如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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公开(公告)号:US07195906B2
公开(公告)日:2007-03-27
申请号:US10783020
申请日:2004-02-23
CPC分类号: C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要: A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译: 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎症活性,特别是胃肠炎症活动如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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公开(公告)号:US20060292133A1
公开(公告)日:2006-12-28
申请号:US11311632
申请日:2005-12-20
CPC分类号: C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要: Lactobacillus salivarius is useful in the prophylaxis or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer. The Lactobacillus salivarius is of human origin isolated from resected and washed human gastrointestinal tract. One such strain is UCC 118 described in WO-A-9835014.
摘要翻译: 唾液乳杆菌可用于预防或治疗不希望的炎性活动,特别是胃肠炎症活动,如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。 唾液乳杆菌是从切除和洗涤的人类胃肠道分离的人源。 一种这样的菌株是在WO-A-9835014中描述的UCC 118。
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公开(公告)号:US20060269534A1
公开(公告)日:2006-11-30
申请号:US11443765
申请日:2006-05-31
申请人: Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Greg Sunvold
发明人: Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Greg Sunvold
CPC分类号: C12R1/01 , A23C9/1234 , A23C19/0323 , A23K10/18 , A23K50/40 , A23K50/42 , A23K50/48 , A61K35/745 , C12N1/20 , Y10S435/822
摘要: According to the invention there is provided a strain of lactic acid bacteria of the genus Bifidobacteria obtainable by isolation from resected and washed feline gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacteria of the present invention are also provided.
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